Persistent gut microbiota immaturity in malnourished Bangladeshi children

Nature

Volumn 510, Issue 7505, 2014, Pages 417-421

  Subramanian, Sathish ^a   Huq, Sayeeda ^b   Yatsunenko, Tanya ^a   Haque, Rashidul ^b   Mahfuz, Mustafa ^b   Alam, Mohammed A ^a,c   Benezra, Amber ^a   Destefano, Joseph ^a   Meier, Martin F ^a   Muegge, Brian D ^a   Barratt, Michael J ^a   VanArendonk, Laura G ^a   Zhang, Qunyuan ^d   Province, Michael A ^d   Petri, William A ^e   Ahmed, Tahmeed ^b   Gordon, Jeffrey I ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

^c NEW SCHOOL FOR SOCIAL RESEARCH   (United States)

^d WASHINGTON UNIVERSITY   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMPICILLIN; GENTAMICIN; RNA 16S;

AGE CLASS; BACTERIUM; CHILD HEALTH; ENVIRONMENTAL FACTOR; FECES; FOOD SECURITY; MALNUTRITION; MICROBIAL COMMUNITY; PERSISTENCE; URBAN AREA;

ANTHROPOMETRIC PARAMETERS; ARTICLE; ARTIFICIAL MILK; BANGLADESH; CHILD; CHILD GROWTH; CHILDHOOD DISEASE; CHILDHOOD MORTALITY; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DIZYGOTIC TWINS; FECES MICROFLORA; FOLLOW UP; FOOD INTAKE; HUMAN; INFANT; INFECTION; INFECTION CONTROL; INTESTINE FLORA; MAJOR CLINICAL STUDY; MALNUTRITION; MATURATION; MICROBIOME; MICROBIOTA IMMATURITY; MONOZYGOTIC TWINS; MULTIPLE PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEVERE ACUTE MALNUTRITION;

BANGLADESH; DHAKA [BANGLADESH];

BACTERIA (MICROORGANISMS);

BACTERIA; BACTERIAL PHYSIOLOGICAL PHENOMENA; BANGLADESH; BIODIVERSITY; FECES; FEMALE; GASTROINTESTINAL TRACT; HUMANS; INFANT; INFANT NUTRITION DISORDERS; MALE; MICROBIOTA; MODELS, BIOLOGICAL; NUTRITIONAL STATUS; RNA, RIBOSOMAL, 16S;

EID: 84903134830     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13421     Document Type: Article

References (28)

1. Ahmed, T. et al.Mortality in severely malnourished children with diarrhoea and use of a standardised management protocol. Lancet 353, 1919-1922 (1999).
2. Ashraf, H. et al. A follow-up experience of 6 months after treatment of children with severe acute malnutrition in Dhaka, Bangladesh. J. Trop. Pediatr. 58, 253-257 (2012).
3. World Health Organization Department of Nutrition for Health and Development. WHO child growth standards growth velocity based on weight, length and head circumference: methods and development. (World Health Organization, 2009).
4. Victora, C. G., de Onis, M., Hallal, P. C., Blössner, M. & Shrimpton, R. Worldwide timing of growth faltering: revisiting implications for interventions. Pediatrics 125, e473-e480 (2010).
5. Ahmed, T. & Begum, B. Badiuzzaman, Ali, M. & Fuchs, G. Management of severe malnutrition and diarrhea. Indian J. Pediatr. 68, 45-51 (2001).
6. Ahmed, T. et al.P0580 Use of a standardized protocol based on local diet results in satisfactory rates of weight gain of severely malnourished children undergoing nutritional rehabilitation. J. Pediatr. Gastroenterol. Nutr. 39, S277 (2004).
7. Lazzerini, M., Rubert, L. & Pani, P. Specially formulated foods for treating children with moderate acute malnutrition in low- and middle-income countries. Cochrane Database Syst. Rev. CD009584 (2013).
8. Prentice, A. M. et al. Critical windows for nutritional interventions against stunting. Am. J. Clin. Nutr. 97, 911-918 (2013).
9. Muegge, B. D. et al. Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science 332, 970-974 (2011).
10. Wu, G. D. et al. Linking long-term dietary patterns with gut microbial enterotypes. Science 334, 105-108 (2011).
11. Yatsunenko, T. et al. Human gut microbiome viewed across age and geography. Nature 486, 222-227 (2012).
12. Smith, M. I. et al. Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Science 339, 548-554 (2013).
13. David, L. A. et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature 505, 559-563 (2014).
14. Tang, W. H. W. et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N. Engl. J. Med. 368, 1575-1584 (2013).
15. Faith, J. J. et al. The long-term stability of the human gut microbiota. Science 341 (2013).
16. Breiman, L. Random Forests. Mach. Learn. 45, 5-32 (2001).
17. Dewey, K. G. et al. Infant weight-for-length is positively associated with subsequent linear growth across four different populations. Matern. Child Nutr. 1,11-20(2005).
18. Lin, A. et al. Distinct distal gut microbiome diversity and composition in healthy children from Bangladesh and the United States. PLoS ONE 8, e53838 (2013).
19. Nahar, B. et al. Effects of a community-based approach of food and psychosocial stimulation on growth and development of severely malnourished children in Bangladesh: a randomised trial. Eur. J. Clin. Nutr. 66, 701-709 (2012).
20. Bates, D., Maechler, M. & Bolker, B. lme4: Linear mixed-effects models using S4 classes. http://CRAN.R-project.org/package5lme4 (2011).
21. Mondal, D. et al. Contribution of enteric infection, altered intestinal barrier function, and maternal malnutrition to infant malnutrition in Bangladesh. Clin. Infect. Dis. 54, 185-192 (2012).
22. Pathela, P. et al. Diarrheal illness in a cohort of children 0-2 years of age in rural Bangladesh: I. Incidence and risk factors. Acta Paediatr. 95, 430-437 (2006).
23. Bokulich, N. A. et al. Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing. Nature Meth. 10, 57-59 (2013).
24. Caparaso, J. G. et al. QIIME allows analysis of high-throughput community sequencing data. Nature Meth. 7, 335-336 (2010).
25. McDonald, D. et al. An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses ofbacteria andarchaea. ISMEJ. 6,610-618 (2012).
26. Liaw, A. & Weiner, M. Classification and regression by randomForest. R package version 4.6-7.R News 2, 18-22 (2002).
27. Kuznetsova, A., Brockhoff, P. B.& Christensen, R. H. B. lmerTest: tests for random and fixed effects for linear mixed effect models (lmer objects of lme4 package). http://CRAN.R-project.org/package5lmerTest (2013).
28. National Institute of Population Research and Training (NIPORT), Mitra and Associates, and ICF International. Bangladesh Demographic and Health Survey 2011. Dhaka, Bangladesh and Calverton, Maryland, USA: NIPORT, Mitra and Associates, and ICF International (2013).