Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Matsuda, Yudai ^a,b,c   Bai, Tongxuan ^b   Phippen, Christopher B W ^a   Nødvig, Christina S ^a   Kjærbølling, Inge ^a   Vesth, Tammi C ^a   Andersen, Mikael R ^a   Mortensen, Uffe H ^a   Gotfredsen, Charlotte H ^a   Abe, Ikuro ^b   Larsen, Thomas O ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF TOKYO   (Japan)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOPEROXIDE; FUNGAL ENZYME; HEME; ISOMERASE; NOVOFUMIGATONIN; UNCLASSIFIED DRUG; 2 OXOGLUTARIC ACID; FUNGAL PROTEIN; IRON; PEROXIDE; PROSTAGLANDIN E SYNTHASE; TERPENE;

CHEMICAL BINDING; ENZYME; ENZYME ACTIVITY; FUNGUS; GENE EXPRESSION; HOMOLOGY; IDENTIFICATION KEY; METABOLITE; MONOTERPENE;

ARTICLE; ASPERGILLUS; ASPERGILLUS NOVOFUMIGATUS; ASPERGILLUS ORYZAE; BIOSYNTHESIS; CRISPR-CAS9 SYSTEM; DECARBOXYLATION; DNA END JOINING REPAIR; EPIMER; GENE DELETION; HETEROLOGOUS EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; ISOMER; LACTONIZATION; METHYLATION; NONHUMAN; OXIDATION; STEREOCHEMISTRY; CATALYSIS; CRISPR CAS SYSTEM; GENETICS; METABOLISM;

ASPERGILLUS; FUNGI;

ASPERGILLUS; BIOSYNTHETIC PATHWAYS; CATALYSIS; CRISPR-CAS SYSTEMS; FUNGAL PROTEINS; GENE DELETION; IRON; KETOGLUTARIC ACIDS; PEROXIDES; PROSTAGLANDIN-E SYNTHASES; TERPENES;

EID: 85049511618     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-04983-2     Document Type: Article

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