Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

Science Translational Medicine

Volumn 10, Issue 447, 2018, Pages

  Lee, Hyun Jae ^a,e   Georgiadou, Athina ^b   Walther, Michael ^c   Nwakanma, Davis ^c   Stewart, Lindsay B ^c   Levin, Michael ^b   Otto, Thomas D ^d,f   Conway, David J ^c   Coin, Lachlan J ^a   Cunnington, Aubrey J ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^e ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; TRANSCRIPTOME;

ARTICLE; CELL ADHESION; CHILD; CLINICAL ARTICLE; COMA; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC VARIABILITY; GRANULOPOIESIS; HOST PATHOGEN INTERACTION; HUMAN; HYPERLACTATEMIA; IMMUNE RESPONSE; LEUKOCYTE; MALARIA FALCIPARUM; MALE; NEUTROPHIL GRANULE; NONHUMAN; PARASITE DEVELOPMENT; PARASITE LOAD; PATHOGEN LOAD; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; SIGNAL TRANSDUCTION; THROMBOCYTOPENIA; TRANSCRIPTOMICS; TRANSLATION REGULATION; VASCULAR ENDOTHELIUM; BLOOD; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; METABOLISM; NEUTROPHIL; PARASITEMIA; PARASITOLOGY; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; SEQUENCE ANALYSIS; SPECIES DIFFERENCE;

CHILD; CHILD, PRESCHOOL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HOST-PATHOGEN INTERACTIONS; HUMANS; MALARIA, FALCIPARUM; MALE; NEUTROPHILS; PARASITEMIA; PLASMODIUM FALCIPARUM; SEQUENCE ANALYSIS, RNA; SPECIES SPECIFICITY;

EID: 85049260442     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aar3619     Document Type: Article

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