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Volumn 547, Issue 7662, 2017, Pages 213-216

Nutrient sensing modulates malaria parasite virulence

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; TRANSCRIPTION FACTOR SNF; TRANSCRIPTOME; PHOSPHOTRANSFERASE;

EID: 85024370548     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature23009     Document Type: Article
Times cited : (124)

References (38)
  • 1
    • 84922789990 scopus 로고    scopus 로고
    • Nutrient-sensing mechanisms and pathways
    • Efeyan, A., Comb, W. C. & Sabatini, D. M. Nutrient-sensing mechanisms and pathways. Nature 517, 302-310 (2015).
    • (2015) Nature , vol.517 , pp. 302-310
    • Efeyan, A.1    Comb, W.C.2    Sabatini, D.M.3
  • 2
    • 84896696867 scopus 로고    scopus 로고
    • Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae
    • Conrad, M. et al. Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae. FEMS Microbiol. Rev. 38, 254-299 (2014).
    • (2014) FEMS Microbiol. Rev , vol.38 , pp. 254-299
    • Conrad, M.1
  • 3
    • 84869845804 scopus 로고    scopus 로고
    • Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state
    • Babbitt, S. E. et al. Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state. Proc. Natl Acad. Sci. USA 109, E3278-E3287 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. E3278-E3287
    • Babbitt, S.E.1
  • 6
    • 84896871162 scopus 로고    scopus 로고
    • Transcriptomics and metabonomics identify essential metabolic signatures in calorie restriction (CR) regulation across multiple mouse strains
    • Collino, S. et al. Transcriptomics and metabonomics identify essential metabolic signatures in calorie restriction (CR) regulation across multiple mouse strains. Metabolites 3, 881-911 (2013).
    • (2013) Metabolites , vol.3 , pp. 881-911
    • Collino, S.1
  • 7
    • 2342647592 scopus 로고    scopus 로고
    • Long-Term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
    • Fontana, L., Meyer, T. E., Klein, S. & Holloszy, J. O. Long-Term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc. Natl Acad. Sci. USA 101, 6659-6663 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 6659-6663
    • Fontana, L.1    Meyer, T.E.2    Klein, S.3    Holloszy, J.O.4
  • 8
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • Fontana, L., Partridge, L. & Longo, V. D. Extending healthy life span-from yeast to humans. Science 328, 321-326 (2010).
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 9
    • 84902257983 scopus 로고    scopus 로고
    • Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice
    • Meidenbauer, J. J., Ta, N. & Seyfried, T. N. Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice. Nutr. Metab. (Lond.) 11, 23 (2014).
    • (2014) Nutr. Metab. (Lond.) , vol.11 , pp. 23
    • Meidenbauer, J.J.1    Ta, N.2    Seyfried, T.N.3
  • 10
    • 0027433266 scopus 로고
    • Amelioration of murine cerebral malaria by dietary restriction
    • Hunt, N. H., Manduci, N. & Thumwood, C. M. Amelioration of murine cerebral malaria by dietary restriction. Parasitology 107, 471-476 (1993).
    • (1993) Parasitology , vol.107 , pp. 471-476
    • Hunt, N.H.1    Manduci, N.2    Thumwood, C.M.3
  • 11
    • 84936973222 scopus 로고    scopus 로고
    • Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression
    • Mejia, P. et al. Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression. Nat. Commun. 6, 6050 (2015).
    • (2015) Nat. Commun , vol.6 , pp. 6050
    • Mejia, P.1
  • 12
    • 84874053235 scopus 로고    scopus 로고
    • Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins
    • Pasini, E. M. et al. Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins. Mol. Cell. Proteomics 12, 426-448 (2013).
    • (2013) Mol. Cell. Proteomics , vol.12 , pp. 426-448
    • Pasini, E.M.1
  • 13
    • 85024382484 scopus 로고    scopus 로고
    • eds Hohmann, S. & Mager, W. H Ch. 2 Springer
    • Gasch, A. P. in Yeast Stress Responses (eds Hohmann, S. & Mager, W. H.) Ch. 2, (Springer, 2003).
    • (2003) Yeast Stress Responses
    • Gasch, A.P.1
  • 14
    • 77958094517 scopus 로고    scopus 로고
    • The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission
    • Tewari, R. et al. The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission. Cell Host Microbe 8, 377-387 (2010).
    • (2010) Cell Host Microbe , vol.8 , pp. 377-387
    • Tewari, R.1
  • 15
    • 41449103202 scopus 로고    scopus 로고
    • Disruption of the PfPK7 gene impairs schizogony and sporogony in the human malaria parasite Plasmodium falciparum
    • Dorin-Semblat, D., Sicard, A., Doerig, C., Ranford-Cartwright, L. & Doerig, C. Disruption of the PfPK7 gene impairs schizogony and sporogony in the human malaria parasite Plasmodium falciparum. Eukaryot. Cell 7, 279-285 (2008).
    • (2008) Eukaryot. Cell , vol.7 , pp. 279-285
    • Dorin-Semblat, D.1    Sicard, A.2    Doerig, C.3    Ranford-Cartwright, L.4    Doerig, C.5
  • 16
    • 84895900845 scopus 로고    scopus 로고
    • Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei
    • Mony, B. M. et al. Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei. Nature 505, 681-685 (2014).
    • (2014) Nature , vol.505 , pp. 681-685
    • Mony, B.M.1
  • 17
    • 0029927806 scopus 로고    scopus 로고
    • PfKIN, an SNF1 type protein kinase of Plasmodium falciparum predominantly expressed in gametocytes
    • Bracchi, V., Langsley, G., Thélu, J., Eling, W. & Ambroise-Thomas, P. PfKIN, an SNF1 type protein kinase of Plasmodium falciparum predominantly expressed in gametocytes. Mol. Biochem. Parasitol. 76, 299-303 (1996).
    • (1996) Mol. Biochem. Parasitol , vol.76 , pp. 299-303
    • Bracchi, V.1    Langsley, G.2    Thélu, J.3    Eling, W.4    Ambroise-Thomas, P.5
  • 18
    • 84868005485 scopus 로고    scopus 로고
    • AMP-Activated protein kinase: A target for drugs both ancient and modern
    • Hardie, D. G., Ross, F. A. & Hawley, S. A. AMP-Activated protein kinase: A target for drugs both ancient and modern. Chem. Biol. 19, 1222-1236 (2012).
    • (2012) Chem. Biol , vol.19 , pp. 1222-1236
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 19
    • 84902259326 scopus 로고    scopus 로고
    • Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases
    • Crozet, P. et al. Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases. Front. Plant Sci. 5, 190 (2014).
    • (2014) Front. Plant Sci , vol.5 , pp. 190
    • Crozet, P.1
  • 20
    • 85047146562 scopus 로고    scopus 로고
    • Complete avian malaria parasite genomes reveal hostspecific parasite evolution in birds and mammals. Preprint at
    • Boehme, U. et al. Complete avian malaria parasite genomes reveal hostspecific parasite evolution in birds and mammals. Preprint at bioRxiv http://dx.doi.org/10.1101/086504 (2016).
    • (2016) BioRxiv
    • Boehme, U.1
  • 21
    • 0034141355 scopus 로고    scopus 로고
    • The regulation of AMP-Activated protein kinase by phosphorylation
    • Stein, S. C., Woods, A., Jones, N. A., Davison, M. D. & Carling, D. The regulation of AMP-Activated protein kinase by phosphorylation. Biochem. J. 345, 437-443 (2000).
    • (2000) Biochem. J , vol.345 , pp. 437-443
    • Stein, S.C.1    Woods, A.2    Jones, N.A.3    Davison, M.D.4    Carling, D.5
  • 22
    • 84861222690 scopus 로고    scopus 로고
    • The ancient drug salicylate directly activates AMP-Activated protein kinase
    • Hawley, S. A. et al. The ancient drug salicylate directly activates AMP-Activated protein kinase. Science 336, 918-922 (2012).
    • (2012) Science , vol.336 , pp. 918-922
    • Hawley, S.A.1
  • 23
    • 84905719900 scopus 로고    scopus 로고
    • Structural basis for AMPK activation: Natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms
    • Calabrese, M. F. et al. Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms. Structure 22, 1161-1172 (2014).
    • (2014) Structure , vol.22 , pp. 1161-1172
    • Calabrese, M.F.1
  • 24
    • 84890963021 scopus 로고    scopus 로고
    • Structural basis of AMPK regulation by small molecule activators
    • Xiao, B. et al. Structural basis of AMPK regulation by small molecule activators. Nat. Commun. 4, 3017 (2013).
    • (2013) Nat. Commun , vol.4 , pp. 3017
    • Xiao, B.1
  • 25
    • 78649747523 scopus 로고    scopus 로고
    • Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating
    • Pankevich, D. E., Teegarden, S. L., Hedin, A. D., Jensen, C. L. & Bale, T. L. Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating. J. Neurosci. 30, 16399-16407 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 16399-16407
    • Pankevich, D.E.1    Teegarden, S.L.2    Hedin, A.D.3    Jensen, C.L.4    Bale, T.L.5
  • 27
    • 84962949589 scopus 로고    scopus 로고
    • Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1, 698 populationbased measurement studies with 192 million participants
    • NCD Risk Factor Collaboration (NCD-RisC)
    • NCD Risk Factor Collaboration (NCD-RisC). Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1, 698 populationbased measurement studies with 192 million participants. Lancet 387, 1377-1396 (2016).
    • (2016) Lancet , vol.387 , pp. 1377-1396
  • 28
    • 84911379021 scopus 로고    scopus 로고
    • Asymptomatic malaria infections: Detectability, transmissibility and public health relevance
    • Bousema, T., Okell, L., Felger, I. & Drakeley, C. Asymptomatic malaria infections: detectability, transmissibility and public health relevance. Nat. Rev. Microbiol. 12, 833-840 (2014).
    • (2014) Nat. Rev. Microbiol , vol.12 , pp. 833-840
    • Bousema, T.1    Okell, L.2    Felger, I.3    Drakeley, C.4
  • 29
    • 34247507377 scopus 로고    scopus 로고
    • High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei
    • Janse, C. J., Ramesar, J. & Waters, A. P. High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei. Nat. Protocols 1, 346-356 (2006).
    • (2006) Nat. Protocols , vol.1 , pp. 346-356
    • Janse, C.J.1    Ramesar, J.2    Waters, A.P.3
  • 30
    • 23844535777 scopus 로고    scopus 로고
    • Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration
    • Franke-Fayard, B. et al. Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc. Natl Acad. Sci. USA 102, 11468-11473 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 11468-11473
    • Franke-Fayard, B.1
  • 31
    • 79952294333 scopus 로고    scopus 로고
    • Interaction of SNF1 protein kinase with its activating kinase Sak1
    • Liu, Y., Xu, X. & Carlson, M. Interaction of SNF1 protein kinase with its activating kinase Sak1. Eukaryot. Cell 10, 313-319 (2011).
    • (2011) Eukaryot. Cell , vol.10 , pp. 313-319
    • Liu, Y.1    Xu, X.2    Carlson, M.3
  • 32
    • 34347206860 scopus 로고    scopus 로고
    • Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method
    • Gietz, R. D. & Schiestl, R. H. Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat. Protocols 2, 35-37 (2007).
    • (2007) Nat. Protocols , vol.2 , pp. 35-37
    • Gietz, R.D.1    Schiestl, R.H.2
  • 33
    • 66149141833 scopus 로고    scopus 로고
    • Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture
    • Lemieux, J. E. et al. Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture. Proc. Natl Acad. Sci. USA 106, 7559-7564 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 7559-7564
    • Lemieux, J.E.1
  • 34
    • 84861956067 scopus 로고    scopus 로고
    • New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community
    • Kafsack, B. F., Painter, H. J. & Llinás, M. New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community. Malar. J. 11, 187 (2012).
    • (2012) Malar. J , vol.11 , pp. 187
    • Kafsack, B.F.1    Painter, H.J.2    Llinás, M.3
  • 35
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim, D. et al. TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 14, R36 (2013).
    • (2013) Genome Biol , vol.14 , pp. R36
    • Kim, D.1
  • 36
    • 75249087100 scopus 로고    scopus 로고
    • EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: A Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 37
    • 84926507971 scopus 로고    scopus 로고
    • Limma powers differential expression analyses for RNA-sequencing and microarray studies
    • Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015).
    • (2015) Nucleic Acids Res , vol.43 , pp. e47
    • Ritchie, M.E.1
  • 38
    • 84858041341 scopus 로고    scopus 로고
    • Differential expression analysis of multifactor RNA-seq experiments with respect to biological variation
    • McCarthy, D. J., Chen, Y. & Smyth, G. K. Differential expression analysis of multifactor RNA-seq experiments with respect to biological variation. Nucleic Acids Res. 40, 4288-4297 (2012).
    • (2012) Nucleic Acids Res , vol.40 , pp. 4288-4297
    • McCarthy, D.J.1    Chen, Y.2    Smyth, G.K.3


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