-
1
-
-
84922789990
-
Nutrient-sensing mechanisms and pathways
-
Efeyan, A., Comb, W. C. & Sabatini, D. M. Nutrient-sensing mechanisms and pathways. Nature 517, 302-310 (2015).
-
(2015)
Nature
, vol.517
, pp. 302-310
-
-
Efeyan, A.1
Comb, W.C.2
Sabatini, D.M.3
-
2
-
-
84896696867
-
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae
-
Conrad, M. et al. Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae. FEMS Microbiol. Rev. 38, 254-299 (2014).
-
(2014)
FEMS Microbiol. Rev
, vol.38
, pp. 254-299
-
-
Conrad, M.1
-
3
-
-
84869845804
-
Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state
-
Babbitt, S. E. et al. Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state. Proc. Natl Acad. Sci. USA 109, E3278-E3287 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. E3278-E3287
-
-
Babbitt, S.E.1
-
4
-
-
84863828202
-
The kinomes of apicomplexan parasites
-
Miranda-Saavedra, D., Gabaldón, T., Barton, G. J., Langsley, G. & Doerig, C. The kinomes of apicomplexan parasites. Microbes Infect. 14, 796-810 (2012).
-
(2012)
Microbes Infect
, vol.14
, pp. 796-810
-
-
Miranda-Saavedra, D.1
Gabaldón, T.2
Barton, G.J.3
Langsley, G.4
Doerig, C.5
-
5
-
-
77954928710
-
Evolution of the TSC1/TSC2-TOR signaling pathway
-
Serfontein, J., Nisbet, R. E., Howe, C. J. & de Vries, P. J. Evolution of the TSC1/TSC2-TOR signaling pathway. Sci. Signal. 3, ra49 (2010).
-
(2010)
Sci. Signal
, vol.3
, pp. ra49
-
-
Serfontein, J.1
Nisbet, R.E.2
Howe, C.J.3
De Vries, P.J.4
-
6
-
-
84896871162
-
Transcriptomics and metabonomics identify essential metabolic signatures in calorie restriction (CR) regulation across multiple mouse strains
-
Collino, S. et al. Transcriptomics and metabonomics identify essential metabolic signatures in calorie restriction (CR) regulation across multiple mouse strains. Metabolites 3, 881-911 (2013).
-
(2013)
Metabolites
, vol.3
, pp. 881-911
-
-
Collino, S.1
-
7
-
-
2342647592
-
Long-Term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
-
Fontana, L., Meyer, T. E., Klein, S. & Holloszy, J. O. Long-Term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc. Natl Acad. Sci. USA 101, 6659-6663 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 6659-6663
-
-
Fontana, L.1
Meyer, T.E.2
Klein, S.3
Holloszy, J.O.4
-
8
-
-
77951176737
-
Extending healthy life span-from yeast to humans
-
Fontana, L., Partridge, L. & Longo, V. D. Extending healthy life span-from yeast to humans. Science 328, 321-326 (2010).
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
9
-
-
84902257983
-
Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice
-
Meidenbauer, J. J., Ta, N. & Seyfried, T. N. Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice. Nutr. Metab. (Lond.) 11, 23 (2014).
-
(2014)
Nutr. Metab. (Lond.)
, vol.11
, pp. 23
-
-
Meidenbauer, J.J.1
Ta, N.2
Seyfried, T.N.3
-
10
-
-
0027433266
-
Amelioration of murine cerebral malaria by dietary restriction
-
Hunt, N. H., Manduci, N. & Thumwood, C. M. Amelioration of murine cerebral malaria by dietary restriction. Parasitology 107, 471-476 (1993).
-
(1993)
Parasitology
, vol.107
, pp. 471-476
-
-
Hunt, N.H.1
Manduci, N.2
Thumwood, C.M.3
-
11
-
-
84936973222
-
Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression
-
Mejia, P. et al. Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression. Nat. Commun. 6, 6050 (2015).
-
(2015)
Nat. Commun
, vol.6
, pp. 6050
-
-
Mejia, P.1
-
12
-
-
84874053235
-
Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins
-
Pasini, E. M. et al. Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins. Mol. Cell. Proteomics 12, 426-448 (2013).
-
(2013)
Mol. Cell. Proteomics
, vol.12
, pp. 426-448
-
-
Pasini, E.M.1
-
13
-
-
85024382484
-
-
eds Hohmann, S. & Mager, W. H Ch. 2 Springer
-
Gasch, A. P. in Yeast Stress Responses (eds Hohmann, S. & Mager, W. H.) Ch. 2, (Springer, 2003).
-
(2003)
Yeast Stress Responses
-
-
Gasch, A.P.1
-
14
-
-
77958094517
-
The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission
-
Tewari, R. et al. The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission. Cell Host Microbe 8, 377-387 (2010).
-
(2010)
Cell Host Microbe
, vol.8
, pp. 377-387
-
-
Tewari, R.1
-
15
-
-
41449103202
-
Disruption of the PfPK7 gene impairs schizogony and sporogony in the human malaria parasite Plasmodium falciparum
-
Dorin-Semblat, D., Sicard, A., Doerig, C., Ranford-Cartwright, L. & Doerig, C. Disruption of the PfPK7 gene impairs schizogony and sporogony in the human malaria parasite Plasmodium falciparum. Eukaryot. Cell 7, 279-285 (2008).
-
(2008)
Eukaryot. Cell
, vol.7
, pp. 279-285
-
-
Dorin-Semblat, D.1
Sicard, A.2
Doerig, C.3
Ranford-Cartwright, L.4
Doerig, C.5
-
16
-
-
84895900845
-
Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei
-
Mony, B. M. et al. Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei. Nature 505, 681-685 (2014).
-
(2014)
Nature
, vol.505
, pp. 681-685
-
-
Mony, B.M.1
-
17
-
-
0029927806
-
PfKIN, an SNF1 type protein kinase of Plasmodium falciparum predominantly expressed in gametocytes
-
Bracchi, V., Langsley, G., Thélu, J., Eling, W. & Ambroise-Thomas, P. PfKIN, an SNF1 type protein kinase of Plasmodium falciparum predominantly expressed in gametocytes. Mol. Biochem. Parasitol. 76, 299-303 (1996).
-
(1996)
Mol. Biochem. Parasitol
, vol.76
, pp. 299-303
-
-
Bracchi, V.1
Langsley, G.2
Thélu, J.3
Eling, W.4
Ambroise-Thomas, P.5
-
18
-
-
84868005485
-
AMP-Activated protein kinase: A target for drugs both ancient and modern
-
Hardie, D. G., Ross, F. A. & Hawley, S. A. AMP-Activated protein kinase: A target for drugs both ancient and modern. Chem. Biol. 19, 1222-1236 (2012).
-
(2012)
Chem. Biol
, vol.19
, pp. 1222-1236
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
19
-
-
84902259326
-
Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases
-
Crozet, P. et al. Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases. Front. Plant Sci. 5, 190 (2014).
-
(2014)
Front. Plant Sci
, vol.5
, pp. 190
-
-
Crozet, P.1
-
20
-
-
85047146562
-
Complete avian malaria parasite genomes reveal hostspecific parasite evolution in birds and mammals. Preprint at
-
Boehme, U. et al. Complete avian malaria parasite genomes reveal hostspecific parasite evolution in birds and mammals. Preprint at bioRxiv http://dx.doi.org/10.1101/086504 (2016).
-
(2016)
BioRxiv
-
-
Boehme, U.1
-
21
-
-
0034141355
-
The regulation of AMP-Activated protein kinase by phosphorylation
-
Stein, S. C., Woods, A., Jones, N. A., Davison, M. D. & Carling, D. The regulation of AMP-Activated protein kinase by phosphorylation. Biochem. J. 345, 437-443 (2000).
-
(2000)
Biochem. J
, vol.345
, pp. 437-443
-
-
Stein, S.C.1
Woods, A.2
Jones, N.A.3
Davison, M.D.4
Carling, D.5
-
22
-
-
84861222690
-
The ancient drug salicylate directly activates AMP-Activated protein kinase
-
Hawley, S. A. et al. The ancient drug salicylate directly activates AMP-Activated protein kinase. Science 336, 918-922 (2012).
-
(2012)
Science
, vol.336
, pp. 918-922
-
-
Hawley, S.A.1
-
23
-
-
84905719900
-
Structural basis for AMPK activation: Natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms
-
Calabrese, M. F. et al. Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms. Structure 22, 1161-1172 (2014).
-
(2014)
Structure
, vol.22
, pp. 1161-1172
-
-
Calabrese, M.F.1
-
24
-
-
84890963021
-
Structural basis of AMPK regulation by small molecule activators
-
Xiao, B. et al. Structural basis of AMPK regulation by small molecule activators. Nat. Commun. 4, 3017 (2013).
-
(2013)
Nat. Commun
, vol.4
, pp. 3017
-
-
Xiao, B.1
-
25
-
-
78649747523
-
Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating
-
Pankevich, D. E., Teegarden, S. L., Hedin, A. D., Jensen, C. L. & Bale, T. L. Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating. J. Neurosci. 30, 16399-16407 (2010).
-
(2010)
J. Neurosci
, vol.30
, pp. 16399-16407
-
-
Pankevich, D.E.1
Teegarden, S.L.2
Hedin, A.D.3
Jensen, C.L.4
Bale, T.L.5
-
26
-
-
0016592485
-
Refeeding-malaria and hyperferraemia
-
Murray, M. J., Murray, N. J., Murray, A. B. & Murray, M. B. Refeeding-malaria and hyperferraemia. Lancet 1, 653-654 (1975).
-
(1975)
Lancet
, vol.1
, pp. 653-654
-
-
Murray, M.J.1
Murray, N.J.2
Murray, A.B.3
Murray, M.B.4
-
27
-
-
84962949589
-
Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1, 698 populationbased measurement studies with 192 million participants
-
NCD Risk Factor Collaboration (NCD-RisC)
-
NCD Risk Factor Collaboration (NCD-RisC). Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1, 698 populationbased measurement studies with 192 million participants. Lancet 387, 1377-1396 (2016).
-
(2016)
Lancet
, vol.387
, pp. 1377-1396
-
-
-
28
-
-
84911379021
-
Asymptomatic malaria infections: Detectability, transmissibility and public health relevance
-
Bousema, T., Okell, L., Felger, I. & Drakeley, C. Asymptomatic malaria infections: detectability, transmissibility and public health relevance. Nat. Rev. Microbiol. 12, 833-840 (2014).
-
(2014)
Nat. Rev. Microbiol
, vol.12
, pp. 833-840
-
-
Bousema, T.1
Okell, L.2
Felger, I.3
Drakeley, C.4
-
29
-
-
34247507377
-
High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei
-
Janse, C. J., Ramesar, J. & Waters, A. P. High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei. Nat. Protocols 1, 346-356 (2006).
-
(2006)
Nat. Protocols
, vol.1
, pp. 346-356
-
-
Janse, C.J.1
Ramesar, J.2
Waters, A.P.3
-
30
-
-
23844535777
-
Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration
-
Franke-Fayard, B. et al. Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc. Natl Acad. Sci. USA 102, 11468-11473 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 11468-11473
-
-
Franke-Fayard, B.1
-
31
-
-
79952294333
-
Interaction of SNF1 protein kinase with its activating kinase Sak1
-
Liu, Y., Xu, X. & Carlson, M. Interaction of SNF1 protein kinase with its activating kinase Sak1. Eukaryot. Cell 10, 313-319 (2011).
-
(2011)
Eukaryot. Cell
, vol.10
, pp. 313-319
-
-
Liu, Y.1
Xu, X.2
Carlson, M.3
-
32
-
-
34347206860
-
Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method
-
Gietz, R. D. & Schiestl, R. H. Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat. Protocols 2, 35-37 (2007).
-
(2007)
Nat. Protocols
, vol.2
, pp. 35-37
-
-
Gietz, R.D.1
Schiestl, R.H.2
-
33
-
-
66149141833
-
Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture
-
Lemieux, J. E. et al. Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture. Proc. Natl Acad. Sci. USA 106, 7559-7564 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 7559-7564
-
-
Lemieux, J.E.1
-
34
-
-
84861956067
-
New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community
-
Kafsack, B. F., Painter, H. J. & Llinás, M. New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community. Malar. J. 11, 187 (2012).
-
(2012)
Malar. J
, vol.11
, pp. 187
-
-
Kafsack, B.F.1
Painter, H.J.2
Llinás, M.3
-
35
-
-
84876996918
-
TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
-
Kim, D. et al. TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 14, R36 (2013).
-
(2013)
Genome Biol
, vol.14
, pp. R36
-
-
Kim, D.1
-
36
-
-
75249087100
-
EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
-
Robinson, M. D., McCarthy, D. J. & Smyth, G. K. edgeR: A Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26, 139-140 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 139-140
-
-
Robinson, M.D.1
McCarthy, D.J.2
Smyth, G.K.3
-
37
-
-
84926507971
-
Limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015).
-
(2015)
Nucleic Acids Res
, vol.43
, pp. e47
-
-
Ritchie, M.E.1
-
38
-
-
84858041341
-
Differential expression analysis of multifactor RNA-seq experiments with respect to biological variation
-
McCarthy, D. J., Chen, Y. & Smyth, G. K. Differential expression analysis of multifactor RNA-seq experiments with respect to biological variation. Nucleic Acids Res. 40, 4288-4297 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 4288-4297
-
-
McCarthy, D.J.1
Chen, Y.2
Smyth, G.K.3
|