-
1
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
20124702
-
Adams PD, Afonine PV, Bunkóczi G, Chen VB, Davis IW, Echols N, Headd JJ, Hung LW, Kapral GJ, Grosse-Kunstleve RW, McCoy AJ, Moriarty NW, Oeffner R, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH. 2010. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta crystallographica. Section D, Biological crystallography 66:213–221. DOI: https://doi.org/10.1107/S0907444909052925, PMID: 20124702
-
(2010)
Acta Crystallographica. Section D, Biological Crystallography
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkóczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
McCoy, A.J.11
Moriarty, N.W.12
Oeffner, R.13
Read, R.J.14
Richardson, D.C.15
Richardson, J.S.16
Terwilliger, T.C.17
Zwart, P.H.18
-
2
-
-
84955307962
-
Sampling the conformational space of the catalytic subunit of human γ-secretase
-
26623517
-
Bai XC, Rajendra E, Yang G, Shi Y, Scheres SH. 2015. Sampling the conformational space of the catalytic subunit of human γ-secretase. eLife 4:e11182. DOI: https://doi.org/10.7554/eLife.11182, PMID: 26623517
-
(2015)
Elife
, vol.4
-
-
Bai, X.C.1
Rajendra, E.2
Yang, G.3
Shi, Y.4
Scheres, S.H.5
-
3
-
-
84959080555
-
EMRinger: Side chain-directed model and map validation for 3D cryo-electron microscopy
-
26280328
-
Barad BA, Echols N, Wang RY, Cheng Y, DiMaio F, Adams PD, Fraser JS. 2015. EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy. Nature Methods 12:943–946. DOI: https://doi.org/10.1038/nmeth.3541, PMID: 26280328
-
(2015)
Nature Methods
, vol.12
, pp. 943-946
-
-
Barad, B.A.1
Echols, N.2
Wang, R.Y.3
Cheng, Y.4
Dimaio, F.5
Adams, P.D.6
Fraser, J.S.7
-
4
-
-
84930667920
-
2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor
-
25953817
-
Bartesaghi A, Merk A, Banerjee S, Matthies D, Wu X, Milne JL, Subramaniam S. 2015. 2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor. Science 348:1147–1151. DOI: https://doi.org/10.1126/science.aab1576, PMID: 25953817
-
(2015)
Science
, vol.348
, pp. 1147-1151
-
-
Bartesaghi, A.1
Merk, A.2
Banerjee, S.3
Matthies, D.4
Wu, X.5
Milne, J.L.6
Subramaniam, S.7
-
5
-
-
85020201461
-
Recent developments in the CCP-EM software suite
-
28580908
-
Burnley T, Palmer CM, Winn M. 2017. Recent developments in the CCP-EM software suite. Acta Crystallographica. Section D, Structural Biology 73:469–477. DOI: https://doi.org/10.1107/S2059798317007859, PMID: 28580908
-
(2017)
Acta Crystallographica. Section D, Structural Biology
, vol.73
, pp. 469-477
-
-
Burnley, T.1
Palmer, C.M.2
Winn, M.3
-
6
-
-
84982803363
-
Structure of the adenosine A(2A) receptor bound to an engineered G protein
-
27462812
-
Carpenter B, Nehmé R, Warne T, Leslie AG, Tate CG. 2016. Structure of the adenosine A(2A) receptor bound to an engineered G protein. Nature 536:104–107. DOI: https://doi.org/10.1038/nature18966, PMID: 27462812
-
(2016)
Nature
, vol.536
, pp. 104-107
-
-
Carpenter, B.1
Nehmé, R.2
Warne, T.3
Leslie, A.G.4
Tate, C.G.5
-
7
-
-
85018328852
-
Engineering a minimal G protein to facilitate crystallisation of G protein-coupled receptors in their active conformation
-
27672048
-
Carpenter B, Tate CG. 2016. Engineering a minimal G protein to facilitate crystallisation of G protein-coupled receptors in their active conformation. Protein engineering, design & selection: PEDS 29:583–593. DOI: https://doi.org/10.1093/protein/gzw049, PMID: 27672048
-
(2016)
Protein Engineering, Design & Selection: PEDS
, vol.29
, pp. 583-593
-
-
Carpenter, B.1
Tate, C.G.2
-
9
-
-
85038004467
-
Expression and purification of mini G proteins from Escherichia coli
-
28480316
-
Carpenter B, Tate CG. 2017b. Expression and purification of mini G proteins from Escherichia coli. Bio-Protocol 7. DOI: https://doi.org/10.21769/BioProtoc.2235, PMID: 28480316
-
(2017)
Bio-Protocol
, vol.7
-
-
Carpenter, B.1
Tate, C.G.2
-
10
-
-
74549178560
-
MolProbity: All-atom structure validation for macromolecular crystallography
-
20057044
-
Chen VB, Arendall WB, Headd JJ, Keedy DA, Immormino RM, Kapral GJ, Murray LW, Richardson JS, Richardson DC. 2010. MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallographica Section D Biological Crystallography 66:12–21. DOI: https://doi.org/10.1107/S0907444909042073, PMID: 20057044
-
(2010)
Acta Crystallographica Section D Biological Crystallography
, vol.66
, pp. 12-21
-
-
Chen, V.B.1
Arendall, W.B.2
Headd, J.J.3
Keedy, D.A.4
Immormino, R.M.5
Kapral, G.J.6
Murray, L.W.7
Richardson, J.S.8
Richardson, D.C.9
-
11
-
-
84858034356
-
Discovery of 1,2,4-triazine derivatives as adenosine A(2A) antagonists using structure based drug design
-
22220592
-
Congreve M, Andrews SP, Doré AS, Hollenstein K, Hurrell E, Langmead CJ, Mason JS, Ng IW, Tehan B, Zhukov A, Weir M, Marshall FH. 2012. Discovery of 1,2,4-triazine derivatives as adenosine A(2A) antagonists using structure based drug design. Journal of Medicinal Chemistry 55:1898–1903. DOI: https://doi.org/10.1021/jm201376w, PMID: 22220592
-
(2012)
Journal of Medicinal Chemistry
, vol.55
, pp. 1898-1903
-
-
Congreve, M.1
Andrews, S.P.2
Doré, A.S.3
Hollenstein, K.4
Hurrell, E.5
Langmead, C.J.6
Mason, J.S.7
Ng, I.W.8
Tehan, B.9
Zhukov, A.10
Weir, M.11
Marshall, F.H.12
-
12
-
-
84914674933
-
Volta potential phase plate for in-focus phase contrast transmission electron microscopy
-
25331897
-
Danev R, Buijsse B, Khoshouei M, Plitzko JM, Baumeister W. 2014. Volta potential phase plate for in-focus phase contrast transmission electron microscopy. PNAS 111:15635–15640. DOI: https://doi.org/10.1073/pnas. 1418377111, PMID: 25331897
-
(2014)
PNAS
, vol.111
, pp. 15635-15640
-
-
Danev, R.1
Buijsse, B.2
Khoshouei, M.3
Plitzko, J.M.4
Baumeister, W.5
-
13
-
-
84893316235
-
Adenosine A2A receptor as a drug discovery target
-
24164628
-
de Lera Ruiz M, Lim YH, Zheng J. 2014. Adenosine A2A receptor as a drug discovery target. Journal of Medicinal Chemistry 57:3623–3650. DOI: https://doi.org/10.1021/jm4011669, PMID: 24164628
-
(2014)
Journal of Medicinal Chemistry
, vol.57
, pp. 3623-3650
-
-
de Lera Ruiz, M.1
Lim, Y.H.2
Zheng, J.3
-
14
-
-
79960181417
-
Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
-
Doré AS, Robertson N, Errey JC, Ng I, Hollenstein K, Tehan B, Hurrell E, Bennett K, Congreve M, Magnani F, Tate CG, Weir M, Marshall FH. 2011. Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine. Structure 19:1283–1293. DOI: https://doi.org/10.1016/j.str.2011.06.014, PMID: 21885291
-
(2011)
Structure
, vol.19
, pp. 1283-1293
-
-
Doré, A.S.1
Robertson, N.2
Errey, J.C.3
Ng, I.4
Hollenstein, K.5
Tehan, B.6
Hurrell, E.7
Bennett, K.8
Congreve, M.9
Magnani, F.10
Tate, C.G.11
Weir, M.12
Marshall, F.H.13
-
16
-
-
84988037279
-
Unravelling biological macromolecules with cryo-electron microscopy
-
27629640
-
Fernandez-Leiro R, Scheres SH. 2016. Unravelling biological macromolecules with cryo-electron microscopy. Nature 537:339–346. DOI: https://doi.org/10.1038/nature19948, PMID: 27629640
-
(2016)
Nature
, vol.537
, pp. 339-346
-
-
Fernandez-Leiro, R.1
Scheres, S.H.2
-
18
-
-
0035209620
-
International union of pharmacology. XXV. nomenclature and classification of adenosine receptors
-
11734617
-
Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J. 2001. International union of pharmacology. XXV. nomenclature and classification of adenosine receptors. Pharmacological Reviews 53:527–552. PMID: 11734617
-
(2001)
Pharmacological Reviews
, vol.53
, pp. 527-552
-
-
Fredholm, B.B.1
Ijzerman, A.P.2
Jacobson, K.A.3
Klotz, K.N.4
Linden, J.5
-
19
-
-
79952033865
-
International union of basic and clinical pharmacology. LXXXI. nomenclature and classification of adenosine receptors–an update
-
21303899
-
Fredholm BB, IJzerman AP, Jacobson KA, Linden J, Müller CE. 2011. International union of basic and clinical pharmacology. LXXXI. nomenclature and classification of adenosine receptors–an update. Pharmacological Reviews 63:1–34. DOI: https://doi.org/10.1124/pr.110.003285, PMID: 21303899
-
(2011)
Pharmacological Reviews
, vol.63
, pp. 1-34
-
-
Fredholm, B.B.1
Ijzerman, A.P.2
Jacobson, K.A.3
Linden, J.4
Müller, C.E.5
-
20
-
-
0029003107
-
The potential and limitations of neutrons, electrons and X-rays for atomic resolution microscopy of unstained biological molecules
-
Henderson R. 1995. The potential and limitations of neutrons, electrons and X-rays for atomic resolution microscopy of unstained biological molecules. Quarterly Reviews of Biophysics 28:171–193. DOI: https://doi. org/10.1017/S003358350000305X, PMID: 7568675
-
(1995)
Quarterly Reviews of Biophysics
, vol.28
, pp. 171-193
-
-
Henderson, R.1
-
21
-
-
84865640480
-
Adenosine A2A antagonists in Parkinson’s disease: What’s next?
-
22585137
-
Hickey P, Stacy M. 2012. Adenosine A2A antagonists in Parkinson’s disease: what’s next? Current Neurology and Neuroscience Reports 12:376–385. DOI: https://doi.org/10.1007/s11910-012-0279-2, PMID: 22585137
-
(2012)
Current Neurology and Neuroscience Reports
, vol.12
, pp. 376-385
-
-
Hickey, P.1
Stacy, M.2
-
22
-
-
84862776818
-
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
-
22286059
-
Hino T, Arakawa T, Iwanari H, Yurugi-Kobayashi T, Ikeda-Suno C, Nakada-Nakura Y, Kusano-Arai O, Weyand S, Shimamura T, Nomura N, Cameron AD, Kobayashi T, Hamakubo T, Iwata S, Murata T. 2012. G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody. Nature 482:237–240. DOI: https://doi.org/10. 1038/nature10750, PMID: 22286059
-
(2012)
Nature
, vol.482
, pp. 237-240
-
-
Hino, T.1
Arakawa, T.2
Iwanari, H.3
Yurugi-Kobayashi, T.4
Ikeda-Suno, C.5
Nakada-Nakura, Y.6
Kusano-Arai, O.7
Weyand, S.8
Shimamura, T.9
Nomura, N.10
Cameron, A.D.11
Kobayashi, T.12
Hamakubo, T.13
Iwata, S.14
Murata, T.15
-
23
-
-
56749103466
-
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist
-
18832607
-
Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. 2008. The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science 322:1211– 1217. DOI: https://doi.org/10.1126/science.1164772, PMID: 18832607
-
(2008)
Science
, vol.322
, pp. 1211-1217
-
-
Jaakola, V.P.1
Griffith, M.T.2
Hanson, M.A.3
Cherezov, V.4
Chien, E.Y.5
Lane, J.R.6
Ijzerman, A.P.7
Stevens, R.C.8
-
24
-
-
85021646321
-
Cryo-EM structure of haemoglobin at 3.2 å determined with the volta phase plate
-
28665412
-
Khoshouei M, Radjainia M, Baumeister W, Danev R. 2017. Cryo-EM structure of haemoglobin at 3.2 å determined with the volta phase plate. Nature Communications 8:16099. DOI: https://doi.org/10.1038/ncomms16099, PMID: 28665412
-
(2017)
Nature Communications
, vol.8
-
-
Khoshouei, M.1
Radjainia, M.2
Baumeister, W.3
Danev, R.4
-
25
-
-
85015864190
-
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
-
Kimanius D, Forsberg BO, Scheres SH, Lindahl E. 2016. Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2. eLife 5:e18722. DOI: https://doi.org/10.7554/eLife.18722, PMID: 27 845625
-
(2016)
Elife
, vol.5
-
-
Kimanius, D.1
Forsberg, B.O.2
Scheres, S.H.3
Lindahl, E.4
-
26
-
-
84935522404
-
Molecular determinants of CGS21680 binding to the human adenosine A2A receptor
-
25762024
-
Lebon G, Edwards PC, Leslie AG, Tate CG. 2015. Molecular determinants of CGS21680 binding to the human adenosine A2A receptor. Molecular Pharmacology 87:907–915. DOI: https://doi.org/10.1124/mol.114.097360, PMID: 25762024
-
(2015)
Molecular Pharmacology
, vol.87
, pp. 907-915
-
-
Lebon, G.1
Edwards, P.C.2
Leslie, A.G.3
Tate, C.G.4
-
27
-
-
79959564813
-
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
-
Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG, Tate CG. 2011. Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature 474:521–525. DOI: https://doi.org/10.1038/nature10136, PMID: 21593763
-
(2011)
Nature
, vol.474
, pp. 521-525
-
-
Lebon, G.1
Warne, T.2
Edwards, P.C.3
Bennett, K.4
Langmead, C.J.5
Leslie, A.G.6
Tate, C.G.7
-
28
-
-
84865304129
-
Agonist-bound structures of G protein-coupled receptors
-
22480933
-
Lebon G, Warne T, Tate CG. 2012. Agonist-bound structures of G protein-coupled receptors. Current Opinion in Structural Biology 22:482–490. DOI: https://doi.org/10.1016/j.sbi.2012.03.007, PMID: 22480933
-
(2012)
Current Opinion in Structural Biology
, vol.22
, pp. 482-490
-
-
Lebon, G.1
Warne, T.2
Tate, C.G.3
-
29
-
-
84941796489
-
A2aR antagonists: Next generation checkpoint blockade for Cancer immunotherapy
-
25941561
-
Leone RD, Lo YC, Powell JD. 2015. A2aR antagonists: next generation checkpoint blockade for Cancer immunotherapy. Computational and Structural Biotechnology Journal 13:265–272. DOI: https://doi.org/10. 1016/j.csbj.2015.03.008, PMID: 25941561
-
(2015)
Computational and Structural Biotechnology Journal
, vol.13
, pp. 265-272
-
-
Leone, R.D.1
Lo, Y.C.2
Powell, J.D.3
-
30
-
-
85042499588
-
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex
-
29466332
-
Liang YL, Khoshouei M, Glukhova A, Furness SGB, Zhao P, Clydesdale L, Koole C, Truong TT, Thal DM, Lei S, Radjainia M, Danev R, Baumeister W, Wang MW, Miller LJ, Christopoulos A, Sexton PM, Wootten D. 2018. Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex. Nature 555:121– 125. DOI: https://doi.org/10.1038/nature25773, PMID: 29466332
-
(2018)
Nature
, vol.555
, pp. 121-125
-
-
Liang, Y.L.1
Khoshouei, M.2
Glukhova, A.3
Furness, S.G.B.4
Zhao, P.5
Clydesdale, L.6
Koole, C.7
Truong, T.T.8
Thal, D.M.9
Lei, S.10
Radjainia, M.11
Danev, R.12
Baumeister, W.13
Wang, M.W.14
Miller, L.J.15
Christopoulos, A.16
Sexton, P.M.17
Wootten, D.18
-
31
-
-
85019746188
-
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex
-
28437792
-
Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM. 2017. Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Nature 546:118–123. DOI: https://doi.org/10.1038/nature22327, PMID: 28437792
-
(2017)
Nature
, vol.546
, pp. 118-123
-
-
Liang, Y.L.1
Khoshouei, M.2
Radjainia, M.3
Zhang, Y.4
Glukhova, A.5
Tarrasch, J.6
Thal, D.M.7
Furness, S.G.B.8
Christopoulos, G.9
Coudrat, T.10
Danev, R.11
Baumeister, W.12
Miller, L.J.13
Christopoulos, A.14
Kobilka, B.K.15
Wootten, D.16
Skiniotis, G.17
Sexton, P.M.18
-
32
-
-
84861961427
-
Structural basis for allosteric regulation of GPCRs by sodium ions
-
22798613
-
Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC. 2012. Structural basis for allosteric regulation of GPCRs by sodium ions. Science 337: 232–236. DOI: https://doi.org/10.1126/science.1219218, PMID: 22798613
-
(2012)
Science
, vol.337
, pp. 232-236
-
-
Liu, W.1
Chun, E.2
Thompson, A.A.3
Chubukov, P.4
Xu, F.5
Katritch, V.6
Han, G.W.7
Roth, C.B.8
Heitman, L.H.9
Ijzerman, A.P.10
Cherezov, V.11
Stevens, R.C.12
-
33
-
-
25644458666
-
Automated electron microscope tomography using robust prediction of specimen movements
-
16182563
-
Mastronarde DN. 2005. Automated electron microscope tomography using robust prediction of specimen movements. Journal of Structural Biology 152:36–51. DOI: https://doi.org/10.1016/j.jsb.2005.07.007, PMID: 16182563
-
(2005)
Journal of Structural Biology
, vol.152
, pp. 36-51
-
-
Mastronarde, D.N.1
-
34
-
-
79953763877
-
REFMAC5 for the refinement of macromolecular crystal structures
-
21460454
-
Murshudov GN, Skubák P, Lebedev AA, Pannu NS, Steiner RA, Nicholls RA, Winn MD, Long F, Vagin AA. 2011. REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallographica Section D Biological Crystallography 67:355–367. DOI: https://doi.org/10.1107/S0907444911001314, PMID: 21460454
-
(2011)
Acta Crystallographica Section D Biological Crystallography
, vol.67
, pp. 355-367
-
-
Murshudov, G.N.1
Skubák, P.2
Lebedev, A.A.3
Pannu, N.S.4
Steiner, R.A.5
Nicholls, R.A.6
Winn, M.D.7
Long, F.8
Vagin, A.A.9
-
35
-
-
85018486920
-
Mini-G proteins: Novel tools for studying GPCRs in their active conformation
-
28426733
-
Nehmé R, Carpenter B, Singhal A, Strege A, Edwards PC, White CF, Du H, Grisshammer R, Tate CG. 2017. Mini-G proteins: Novel tools for studying GPCRs in their active conformation. PLoS One 12:e0175642. DOI: https://doi.org/10.1371/journal.pone.0175642, PMID: 28426733
-
(2017)
Plos One
, vol.12
-
-
Nehmé, R.1
Carpenter, B.2
Singhal, A.3
Strege, A.4
Edwards, P.C.5
White, C.F.6
Du, H.7
Grisshammer, R.8
Tate, C.G.9
-
36
-
-
84860269955
-
Low-resolution refinement tools in REFMAC5
-
22505260
-
Nicholls RA, Long F, Murshudov GN. 2012. Low-resolution refinement tools in REFMAC5. Acta Crystallographica. Section D, Biological Crystallography 68:404–417. DOI: https://doi.org/10.1107/S090744491105606X, PMID: 22505260
-
(2012)
Acta Crystallographica. Section D, Biological Crystallography
, vol.68
, pp. 404-417
-
-
Nicholls, R.A.1
Long, F.2
Murshudov, G.N.3
-
37
-
-
80051658642
-
Crystal structure of the β2 adrenergic receptor-Gs protein complex
-
21772288
-
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. 2011. Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature 477:549–555. DOI: https://doi.org/10.1038/nature10361, PMID: 21772288
-
(2011)
Nature
, vol.477
, pp. 549-555
-
-
Rasmussen, S.G.1
Devree, B.T.2
Zou, Y.3
Kruse, A.C.4
Chung, K.Y.5
Kobilka, T.S.6
Thian, F.S.7
Chae, P.S.8
Pardon, E.9
Calinski, D.10
Mathiesen, J.M.11
Shah, S.T.12
Lyons, J.A.13
Caffrey, M.14
Gellman, S.H.15
Steyaert, J.16
Skiniotis, G.17
Weis, W.I.18
Sunahara, R.K.19
Kobilka, B.K.20
more..
-
38
-
-
0142042865
-
Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy
-
14568533
-
Rosenthal PB, Henderson R. 2003. Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy. Journal of Molecular Biology 333:721–745. DOI: https://doi.org/10.1016/j.jmb.2003.07.013, PMID: 14568533
-
(2003)
Journal of Molecular Biology
, vol.333
, pp. 721-745
-
-
Rosenthal, P.B.1
Henderson, R.2
-
39
-
-
85040442935
-
2A Receptor crystals
-
29311713
-
2A Receptor crystals. Scientific Reports 88:41. DOI: https://doi.org/10.1038/s41598-017-18570-w, PMID: 29311713
-
(2018)
Scientific Reports
, vol.88
, pp. 41
-
-
Rucktooa, P.1
Cheng, R.K.Y.2
Segala, E.3
Geng, T.4
Errey, J.C.5
Brown, G.A.6
Cooke, R.M.7
Marshall, F.H.8
Doré, A.S.9
-
40
-
-
84868444740
-
RELION: Implementation of a bayesian approach to cryo-EM structure determination
-
23000701
-
Scheres SH. 2012. RELION: implementation of a bayesian approach to cryo-EM structure determination. Journal of Structural Biology 180:519–530. DOI: https://doi.org/10.1016/j.jsb.2012.09.006, PMID: 23000701
-
(2012)
Journal of Structural Biology
, vol.180
, pp. 519-530
-
-
Scheres, S.H.1
-
41
-
-
84922727036
-
Semi-automated selection of cryo-EM particles in RELION-1.3
-
25486611
-
Scheres SH. 2015. Semi-automated selection of cryo-EM particles in RELION-1.3. Journal of Structural Biology 189:114–122. DOI: https://doi.org/10.1016/j.jsb.2014.11.010, PMID: 25486611
-
(2015)
Journal of Structural Biology
, vol.189
, pp. 114-122
-
-
Scheres, S.H.1
-
42
-
-
84978734536
-
Controlling the dissociation of ligands from the adenosine A2A receptor through modulation of salt bridge strength
-
27312113
-
Segala E, Guo D, Cheng RK, Bortolato A, Deflorian F, Doré AS, Errey JC, Heitman LH, IJzerman AP, Marshall FH, Cooke RM. 2016. Controlling the dissociation of ligands from the adenosine A2A receptor through modulation of salt bridge strength. Journal of Medicinal Chemistry 59:6470–6479. DOI: https://doi.org/10.1021/acs. jmedchem.6b00653, PMID: 27312113
-
(2016)
Journal of Medicinal Chemistry
, vol.59
, pp. 6470-6479
-
-
Segala, E.1
Guo, D.2
Cheng, R.K.3
Bortolato, A.4
Deflorian, F.5
Doré, A.S.6
Errey, J.C.7
Heitman, L.H.8
Ijzerman, A.P.9
Marshall, F.H.10
Cooke, R.M.11
-
43
-
-
85013250295
-
2A receptor bound to an antagonist reveals a potential allosteric pocket
-
28167788
-
2A receptor bound to an antagonist reveals a potential allosteric pocket. PNAS 114:2066–2071. DOI: https://doi.org/10.1073/pnas.1621423114, PMID: 28167788
-
(2017)
PNAS
, vol.114
, pp. 2066-2071
-
-
Sun, B.1
Bachhawat, P.2
Chu, M.L.3
Wood, M.4
Ceska, T.5
Sands, Z.A.6
Mercier, J.7
Lebon, F.8
Kobilka, T.S.9
Kobilka, B.K.10
-
44
-
-
69249146075
-
Engineering G protein-coupled receptors to facilitate their structure determination
-
Tate CG, Schertler GF. 2009. Engineering G protein-coupled receptors to facilitate their structure determination. Current Opinion in Structural Biology 19:386–395. DOI: https://doi.org/10.1016/j.sbi.2009.07.004, PMID: 19682 887
-
(2009)
Current Opinion in Structural Biology
, vol.19
, pp. 386-395
-
-
Tate, C.G.1
Schertler, G.F.2
-
45
-
-
77950496251
-
Practical considerations of membrane protein instability during purification and crystallisation
-
Tate CG. 2010. Practical considerations of membrane protein instability during purification and crystallisation. Methods in Molecular Biology 601:187–203. DOI: https://doi.org/10.1007/978-1-60761-344-2_12, PMID: 200 99147
-
(2010)
Methods in Molecular Biology
, vol.601
, pp. 187-203
-
-
Tate, C.G.1
-
46
-
-
0028172426
-
Binding of an alpha 2 adrenergic receptor third intracellular loop peptide to G beta and the amino terminus of G alpha
-
7961678
-
Taylor JM, Jacob-Mosier GG, Lawton RG, Remmers AE, Neubig RR. 1994. Binding of an alpha 2 adrenergic receptor third intracellular loop peptide to G beta and the amino terminus of G alpha. The Journal of Biological Chemistry 269:27618–27624. PMID: 7961678
-
(1994)
The Journal of Biological Chemistry
, vol.269
, pp. 27618-27624
-
-
Taylor, J.M.1
Jacob-Mosier, G.G.2
Lawton, R.G.3
Remmers, A.E.4
Neubig, R.R.5
-
47
-
-
0030064529
-
Receptor and membrane interaction sites on gbeta. A receptor-derived peptide binds to the carboxyl terminus
-
8631928
-
Taylor JM, Jacob-Mosier GG, Lawton RG, VanDort M, Neubig RR. 1996. Receptor and membrane interaction sites on gbeta. A receptor-derived peptide binds to the carboxyl terminus. The Journal of Biological Chemistry 271:3336–3339. PMID: 8631928
-
(1996)
The Journal of Biological Chemistry
, vol.271
, pp. 3336-3339
-
-
Taylor, J.M.1
Jacob-Mosier, G.G.2
Lawton, R.G.3
Vandort, M.4
Neubig, R.R.5
-
48
-
-
84873685831
-
Molecular signatures of G-protein-coupled receptors
-
23407534
-
Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM. 2013. Molecular signatures of G-protein-coupled receptors. Nature 494:185–194. DOI: https://doi.org/10.1038/nature11896, PMID: 23407534
-
(2013)
Nature
, vol.494
, pp. 185-194
-
-
Venkatakrishnan, A.J.1
Deupi, X.2
Lebon, G.3
Tate, C.G.4
Schertler, G.F.5
Babu, M.M.6
-
49
-
-
84988039141
-
Single particle electron cryomicroscopy: Trends, issues and future perspective
-
DOI
-
Vinothkumar KR, Henderson R. 2016. Single particle electron cryomicroscopy: trends, issues and future perspective. Quarterly Reviews of Biophysics 49:e13. DOI: https://doi.org/10.1017/S0033583516000068, PMID: 27658821
-
(2016)
Quarterly Reviews of Biophysics
, vol.49
-
-
Vinothkumar, K.R.1
Henderson, R.2
-
50
-
-
79954782236
-
Structure of an agonist-bound human A2A adenosine receptor
-
21393508
-
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. 2011. Structure of an agonist-bound human A2A adenosine receptor. Science 332:322–327. DOI: https://doi.org/10.1126/science.1202793, PMID: 21393508
-
(2011)
Science
, vol.332
, pp. 322-327
-
-
Xu, F.1
Wu, H.2
Katritch, V.3
Han, G.W.4
Jacobson, K.A.5
Gao, Z.G.6
Cherezov, V.7
Stevens, R.C.8
-
51
-
-
84955216953
-
Gctf: Real-time CTF determination and correction
-
26592709
-
Zhang K. 2016. Gctf: real-time CTF determination and correction. Journal of Structural Biology 193:1–12. DOI: https://doi.org/10.1016/j.jsb.2015.11.003, PMID: 26592709
-
(2016)
Journal of Structural Biology
, vol.193
, pp. 1-12
-
-
Zhang, K.1
-
52
-
-
85020380548
-
Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein
-
28538729
-
Zhang Y, Sun B, Feng D, Hu H, Chu M, Qu Q, Tarrasch JT, Li S, Sun Kobilka T, Kobilka BK, Skiniotis G. 2017. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature 546:248–253. DOI: https://doi.org/10.1038/nature22394, PMID: 28538729
-
(2017)
Nature
, vol.546
, pp. 248-253
-
-
Zhang, Y.1
Sun, B.2
Feng, D.3
Hu, H.4
Chu, M.5
Qu, Q.6
Tarrasch, J.T.7
Li, S.8
Sun Kobilka, T.9
Kobilka, B.K.10
Skiniotis, G.11
-
53
-
-
85014129582
-
MotionCor2: Anisotropic correction of beam-induced motion for improved cryo-electron microscopy
-
Zheng SQ, Palovcak E, Armache JP, Verba KA, Cheng Y, Agard DA. 2017. MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy. Nature Methods 14:331–332. DOI: https://doi. org/10.1038/nmeth.4193, PMID: 28250466
-
(2017)
Nature Methods
, vol.14
, pp. 331-332
-
-
Zheng, S.Q.1
Palovcak, E.2
Armache, J.P.3
Verba, K.A.4
Cheng, Y.5
Agard, D.A.6
|