2.2 å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor

Science

Volumn 348, Issue 6239, 2015, Pages 1147-1151

  Bartesaghi, Alberto ^a   Merk, Alan ^a   Banerjee, Soojay ^a   Matthies, Doreen ^a   Wu, Xiongwu ^b   Milne, Jacqueline L S ^a   Subramaniam, Sriram ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; MAGNESIUM; PHENYLETHYL BETA DEXTRO THIOGALACTOPYRANOSIDE; PYRANOSIDE; SODIUM ION; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN; PHENYLETHYLTHIO-BETA-GALACTOPYRANOSIDE; THIOGLYCOSIDE; WATER;

BACTERIUM; BIOCHEMISTRY; ELECTRON MICROSCOPY; ENZYME; INHIBITOR; LIGAND; MAGNESIUM; PROTEIN; RESOLUTION; SODIUM;

ARTICLE; CRYSTAL STRUCTURE; DATA PROCESSING; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ESCHERICHIA COLI; HYDROGEN BOND; HYPOCREA JECORINA; IMAGE PROCESSING; INFORMATION PROCESSING; NONHUMAN; NUCLEIC ACID STRUCTURE; PRIORITY JOURNAL; SURFACE PROPERTY; X RAY CRYSTALLOGRAPHY; CHEMISTRY; CRYOELECTRON MICROSCOPY; ENZYME ACTIVE SITE; ENZYMOLOGY;

ESCHERICHIA COLI B;

BETA-GALACTOSIDASE; CATALYTIC DOMAIN; CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; THIOGALACTOSIDES; WATER;

EID: 84930667920     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aab1576     Document Type: Article

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