Structure of the adenosine A2A receptor bound to an engineered G protein

Nature

Volumn 536, Issue 7614, 2016, Pages 104-107

  Carpenter, Byron ^a   Nehmé, Rony ^a   Warne, Tony ^a   Leslie, Andrew G W ^a   Tate, Christopher G ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2A RECEPTOR; ARGININE; G PROTEIN MINI GS; GUANINE NUCLEOTIDE BINDING PROTEIN; TYROSINE; UNCLASSIFIED DRUG; ADENOSINE A2 RECEPTOR AGONIST; BETA 2 ADRENERGIC RECEPTOR; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND;

AMINO ACID; CHEMICAL BINDING; GENETIC ENGINEERING; LIGAND; MOLECULAR ANALYSIS; PROTEIN; SENSORY SYSTEM;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; CRYSTALLIZATION; ENZYME SPECIFICITY; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; X RAY CRYSTALLOGRAPHY;

ADENOSINE A2 RECEPTOR AGONISTS; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; CYTOPLASM; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RECEPTOR, ADENOSINE A2A; RECEPTORS, ADRENERGIC, BETA-2; SUBSTRATE SPECIFICITY;

EID: 84982803363     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature18966     Document Type: Article

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