The Drosophila Immune Deficiency Pathway Modulates Enteroendocrine Function and Host Metabolism

Cell Metabolism

Volumn 28, Issue 3, 2018, Pages 449-462.e5

  Kamareddine, Layla ^a   Robins, William P ^b   Berkey, Cristin D ^a   Mekalanos, John J ^b   Watnick, Paula I ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Drosophila insulin like peptide 3; enteroendocrine cell; enteroendocrine peptide; immune deficiency pathway; innate immunity; lipid droplet; metabolism; PGRP LC; short chain fatty acid; tachykinin

Indexed keywords

ACETIC ACID; INSECT PROTEIN; INSULIN; PEPTIDOGLYCAN RECOGNITION PROTEIN; PEPTIDOGLYCAN RECOGNITION PROTEIN LC; RELISH PROTEIN; TACHYKININ; UNCLASSIFIED DRUG; CARRIER PROTEIN; DROSOPHILA PROTEIN; IMD PROTEIN, DROSOPHILA; PROTEIN PRECURSOR; TK PROTEIN, DROSOPHILA; VOLATILE FATTY ACID;

ACETOBACTER; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROL; CONTROLLED STUDY; DROSOPHILA; ENTEROENDOCRINE CELL; FEMALE; GENE KNOCKDOWN; GENETIC TRANSCRIPTION; IMMUNE DEFICIENCY; INNATE IMMUNITY; INSULIN SIGNALING; INTESTINE EPITHELIUM; INTESTINE FLORA; LACTOBACILLUS PLANTARUM; LARVAL DEVELOPMENT; LIPID METABOLISM; METABOLISM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; DROSOPHILA MELANOGASTER; IMMUNOLOGY; INTESTINE; MICROBIOLOGY;

ANIMALS; CARRIER PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENTEROENDOCRINE CELLS; FATTY ACIDS, VOLATILE; GASTROINTESTINAL MICROBIOME; IMMUNITY, INNATE; INSULIN; INTESTINES; LIPID METABOLISM; PROTEIN PRECURSORS; SIGNAL TRANSDUCTION; TACHYKININS;

EID: 85048539275     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2018.05.026     Document Type: Article

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