GSD MD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever

Journal of Experimental Medicine

Volumn 215, Issue 6, 2018, Pages 1519-1529

  Kanneganti, Apurva ^a,b,c,d,e   Malireddi, R K Subbarao ^f   Saavedra, Pedro H V ^a,b   Walle, Lieselotte Vande ^a,b   Van Gorp, Hanne ^a,b   Kambara, Hiroto ^d,e   Tillman, Heather ^f   Vogel, Peter ^f   Luo, Hongbo R ^d,e   Xavier, Ramnik J ^c,g   Chi, Hongbo ^f   Lamkanfi, Mohamed ^a,b,h  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^h JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHIMERIC PROTEIN; GASDERMIN D; INFLAMMASOME; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 1BETA; RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASE C; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; AUTACOID; CYTOKINE; GSDMD PROTEIN, MOUSE; MEFV PROTEIN, MOUSE; PYRIN;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOINFLAMMATORY DISEASE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FAMILIAL MEDITERRANEAN FEVER; GENE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MACROPHAGE; MEFV GENE; MISSENSE MUTATION; MOUSE; NEUTROPHILIA; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYROPTOSIS; TISSUE INJURY; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; INFLAMMATION; METABOLISM; MICROBIOLOGY; NEUTROPHIL; PATHOLOGY; PEPTOCLOSTRIDIUM DIFFICILE; PHYSIOLOGY; SPLEEN; WASTING SYNDROME;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CLOSTRIDIUM DIFFICILE; CYTOKINES; DISEASE MODELS, ANIMAL; FAMILIAL MEDITERRANEAN FEVER; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MACROPHAGES; MICE; NEUTROPHILS; PYRIN; PYROPTOSIS; SPLEEN; WASTING SYNDROME;

EID: 85048103635     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20172060     Document Type: Article

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