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Volumn 94, Issue 2, 2018, Pages 315-325

Interleukin-6 contributes to the increase in fibroblast growth factor 23 expression in acute and chronic kidney disease

Author keywords

chronic inflammation; cytokines; mineral metabolism; osteoblasts; STAT3

Indexed keywords

DEXAMETHASONE; FIBROBLAST GROWTH FACTOR 23; INTERLEUKIN 6; MESSENGER RNA; STAT3 PROTEIN; ADENINE; FIBROBLAST GROWTH FACTOR; FOLIC ACID; FUSION PROTEIN; GLUCOCORTICOID; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN-6, MOUSE; STAT3 PROTEIN, MOUSE;

EID: 85047762467     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2018.02.026     Document Type: Article
Times cited : (126)

References (53)
  • 1
    • 49249104701 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis
    • Gutierrez, O.M., Mannstadt, M., Isakova, T., et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 359 (2008), 584–592.
    • (2008) N Engl J Med , vol.359 , pp. 584-592
    • Gutierrez, O.M.1    Mannstadt, M.2    Isakova, T.3
  • 2
    • 85041467059 scopus 로고    scopus 로고
    • Longitudinal FGF23 trajectories and mortality in patients with CKD
    • Isakova, T., Cai, X., Lee, J., et al. Longitudinal FGF23 trajectories and mortality in patients with CKD. J Am Soc Nephrol 29 (2018), 579–590.
    • (2018) J Am Soc Nephrol , vol.29 , pp. 579-590
    • Isakova, T.1    Cai, X.2    Lee, J.3
  • 3
    • 64949097327 scopus 로고    scopus 로고
    • Latest findings in phosphate homeostasis
    • Prie, D., Urena, T.P., Friedlander, G., Latest findings in phosphate homeostasis. Kidney Int 75 (2009), 882–889.
    • (2009) Kidney Int , vol.75 , pp. 882-889
    • Prie, D.1    Urena, T.P.2    Friedlander, G.3
  • 4
    • 1642416884 scopus 로고    scopus 로고
    • Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
    • Shimada, T., Kakitani, M., Yamazaki, Y., et al. Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest 113 (2004), 561–568.
    • (2004) J Clin Invest , vol.113 , pp. 561-568
    • Shimada, T.1    Kakitani, M.2    Yamazaki, Y.3
  • 5
    • 36849017126 scopus 로고    scopus 로고
    • The parathyroid is a target organ for FGF23 in rats
    • Ben Dov, I.Z., Galitzer, H., Lavi-Moshayoff, V., et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 117 (2007), 4003–4008.
    • (2007) J Clin Invest , vol.117 , pp. 4003-4008
    • Ben Dov, I.Z.1    Galitzer, H.2    Lavi-Moshayoff, V.3
  • 6
    • 35848947037 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells
    • Krajisnik, T., Bjorklund, P., Marsell, R., et al. Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells. J Endocrinol 195 (2007), 125–131.
    • (2007) J Endocrinol , vol.195 , pp. 125-131
    • Krajisnik, T.1    Bjorklund, P.2    Marsell, R.3
  • 8
    • 74449094013 scopus 로고    scopus 로고
    • Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease
    • Galitzer, H., Ben Dov, I.Z., Silver, J., et al. Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease. Kidney Int 77 (2010), 211–218.
    • (2010) Kidney Int , vol.77 , pp. 211-218
    • Galitzer, H.1    Ben Dov, I.Z.2    Silver, J.3
  • 9
    • 74449086740 scopus 로고    scopus 로고
    • Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients
    • Komaba, H., Goto, S., Fujii, H., et al. Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients. Kidney Int 77 (2010), 232–238.
    • (2010) Kidney Int , vol.77 , pp. 232-238
    • Komaba, H.1    Goto, S.2    Fujii, H.3
  • 10
    • 17744395066 scopus 로고    scopus 로고
    • The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting
    • White, K.E., Jonsson, K.B., Carn, G., et al. The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting. J Clin Endocrinol Metab 86 (2001), 497–500.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 497-500
    • White, K.E.1    Jonsson, K.B.2    Carn, G.3
  • 11
    • 33745828096 scopus 로고    scopus 로고
    • Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis - secretion of fibroblast growth factor 23 requires O-glycosylation
    • Kato, K., Jeanneau, C., Tarp, M.A., et al. Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis - secretion of fibroblast growth factor 23 requires O-glycosylation. J Biol Chem 281 (2006), 18370–18377.
    • (2006) J Biol Chem , vol.281 , pp. 18370-18377
    • Kato, K.1    Jeanneau, C.2    Tarp, M.A.3
  • 12
    • 77957993384 scopus 로고    scopus 로고
    • PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop
    • Lavi-Moshayoff, V., Wasserman, G., Meir, T., et al. PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop. Am J Physiol Renal Physiol 299 (2010), F882–F889.
    • (2010) Am J Physiol Renal Physiol , vol.299 , pp. F882-F889
    • Lavi-Moshayoff, V.1    Wasserman, G.2    Meir, T.3
  • 13
    • 84890806413 scopus 로고    scopus 로고
    • FGF-23 and secondary hyperparathyroidism in chronic kidney disease
    • Silver, J., Naveh-Many, T., FGF-23 and secondary hyperparathyroidism in chronic kidney disease. Nat Rev Nephrol 9 (2013), 641–649.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 641-649
    • Silver, J.1    Naveh-Many, T.2
  • 14
    • 84964267910 scopus 로고    scopus 로고
    • Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription
    • Meir, T., Durlacher, K., Pan, Z., et al. Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription. Kidney Int 86 (2014), 1106–1115.
    • (2014) Kidney Int , vol.86 , pp. 1106-1115
    • Meir, T.1    Durlacher, K.2    Pan, Z.3
  • 15
    • 84956870443 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia
    • Hassan, A., Durlacher, K., Silver, J., et al. The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia. Am J Physiol Renal Physiol 310 (2015), F217–F221.
    • (2015) Am J Physiol Renal Physiol , vol.310 , pp. F217-F221
    • Hassan, A.1    Durlacher, K.2    Silver, J.3
  • 16
    • 85017509498 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 regulation by systemic and local osteoblast-synthesized 1,25-dihydroxyvitamin D
    • Nguyen-Yamamoto, L., Karaplis, A.C., St-Arnaud, R., et al. Fibroblast growth factor 23 regulation by systemic and local osteoblast-synthesized 1,25-dihydroxyvitamin D. J Am Soc Nephrol 28 (2017), 586–597.
    • (2017) J Am Soc Nephrol , vol.28 , pp. 586-597
    • Nguyen-Yamamoto, L.1    Karaplis, A.C.2    St-Arnaud, R.3
  • 17
    • 84864750137 scopus 로고    scopus 로고
    • Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone
    • Krieger, N.S., Culbertson, C.D., Kyker-Snowman, K., et al. Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone. Am J Physiol Renal Physiol 303 (2012), F431–F436.
    • (2012) Am J Physiol Renal Physiol , vol.303 , pp. F431-F436
    • Krieger, N.S.1    Culbertson, C.D.2    Kyker-Snowman, K.3
  • 18
    • 84927949848 scopus 로고    scopus 로고
    • Membrane and integrative nuclear fibroblastic growth factor receptor (FGFR) regulation of FGF-23
    • Han, X., Xiao, Z., Quarles, L.D., Membrane and integrative nuclear fibroblastic growth factor receptor (FGFR) regulation of FGF-23. J Biol Chem 290 (2015), 10447–10459.
    • (2015) J Biol Chem , vol.290 , pp. 10447-10459
    • Han, X.1    Xiao, Z.2    Quarles, L.D.3
  • 19
    • 84946130633 scopus 로고    scopus 로고
    • Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production
    • David, V., Martin, A., Isakova, T., et al. Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production. Kidney Int 89 (2016), 135–146.
    • (2016) Kidney Int , vol.89 , pp. 135-146
    • David, V.1    Martin, A.2    Isakova, T.3
  • 20
    • 84881241741 scopus 로고    scopus 로고
    • Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women
    • Wolf, M., Koch, T.A., Bregman, D.B., Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women. J Bone Miner Res 28 (2013), 1793–1803.
    • (2013) J Bone Miner Res , vol.28 , pp. 1793-1803
    • Wolf, M.1    Koch, T.A.2    Bregman, D.B.3
  • 21
    • 33846096308 scopus 로고    scopus 로고
    • Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury
    • Hoke, T.S., Douglas, I.S., Klein, C.L., et al. Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury. J Am Soc Nephrol 18 (2007), 155–164.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 155-164
    • Hoke, T.S.1    Douglas, I.S.2    Klein, C.L.3
  • 22
    • 84951570571 scopus 로고    scopus 로고
    • Key role of the kidney in the regulation of fibroblast growth factor 23
    • Mace, M.L., Gravesen, E., Hofman-Bang, J., et al. Key role of the kidney in the regulation of fibroblast growth factor 23. Kidney Int 88 (2015), 1304–1313.
    • (2015) Kidney Int , vol.88 , pp. 1304-1313
    • Mace, M.L.1    Gravesen, E.2    Hofman-Bang, J.3
  • 23
    • 84885300497 scopus 로고    scopus 로고
    • Plasma FGF23 levels increase rapidly after acute kidney injury
    • Christov, M., Waikar, S.S., Pereira, R.C., et al. Plasma FGF23 levels increase rapidly after acute kidney injury. Kidney Int 84 (2013), 776–785.
    • (2013) Kidney Int , vol.84 , pp. 776-785
    • Christov, M.1    Waikar, S.S.2    Pereira, R.C.3
  • 24
    • 84979011044 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease
    • Singh, S., Grabner, A., Yanucil, C., et al. Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease. Kidney Int 90 (2016), 985–996.
    • (2016) Kidney Int , vol.90 , pp. 985-996
    • Singh, S.1    Grabner, A.2    Yanucil, C.3
  • 25
  • 26
    • 0028175027 scopus 로고
    • Plasma levels of IL-1β TNFα and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients
    • Pereira, B.J.G., Shapiro, L., King, A.J., et al. Plasma levels of IL-1β TNFα and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients. Kidney Int 45 (1994), 890–896.
    • (1994) Kidney Int , vol.45 , pp. 890-896
    • Pereira, B.J.G.1    Shapiro, L.2    King, A.J.3
  • 27
    • 77949540909 scopus 로고    scopus 로고
    • Plasma interleukin-6 is independently associated with mortality in both hemodialysis and pre-dialysis patients with chronic kidney disease
    • Barreto, D.V., Barreto, F.C., Liabeuf, S., et al. Plasma interleukin-6 is independently associated with mortality in both hemodialysis and pre-dialysis patients with chronic kidney disease. Kidney Int 77 (2010), 550–556.
    • (2010) Kidney Int , vol.77 , pp. 550-556
    • Barreto, D.V.1    Barreto, F.C.2    Liabeuf, S.3
  • 28
    • 85018447093 scopus 로고    scopus 로고
    • Interleukin-6 signaling pathway and its role in kidney disease: an update
    • Su, H., Lei, C.-T., Zhang, C., Interleukin-6 signaling pathway and its role in kidney disease: an update. Front Immunol, 8, 2017, 405.
    • (2017) Front Immunol , vol.8 , pp. 405
    • Su, H.1    Lei, C.-T.2    Zhang, C.3
  • 29
    • 85010749584 scopus 로고    scopus 로고
    • Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease
    • Munoz Mendoza, J., Isakova, T., Cai, X., et al. Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease. Kidney Int 91 (2017), 711–719.
    • (2017) Kidney Int , vol.91 , pp. 711-719
    • Munoz Mendoza, J.1    Isakova, T.2    Cai, X.3
  • 30
    • 48049096638 scopus 로고    scopus 로고
    • IL-6/IL-6R axis plays a critical role in acute kidney injury
    • Nechemia-Arbely, Y., Barkan, D., Pizov, G., et al. IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol 19 (2008), 1106–1115.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1106-1115
    • Nechemia-Arbely, Y.1    Barkan, D.2    Pizov, G.3
  • 31
    • 0344236404 scopus 로고    scopus 로고
    • Leukemia inhibitory factor is involved in tubular regeneration after experimental acute renal failure
    • Yoshino, J., Monkawa, T., Tsuji, M., et al. Leukemia inhibitory factor is involved in tubular regeneration after experimental acute renal failure. J Am Soc Nephrol 14 (2003), 3090–3101.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 3090-3101
    • Yoshino, J.1    Monkawa, T.2    Tsuji, M.3
  • 32
    • 0034653592 scopus 로고    scopus 로고
    • Prominent and sustained up-regulation of gp130-signaling cytokines and the chemokine MIP-2 in murine renal ischemia-reperfusion injury
    • Lemay, S., Rabb, H., Postler, G., et al. Prominent and sustained up-regulation of gp130-signaling cytokines and the chemokine MIP-2 in murine renal ischemia-reperfusion injury. Transplantation 69 (2000), 959–963.
    • (2000) Transplantation , vol.69 , pp. 959-963
    • Lemay, S.1    Rabb, H.2    Postler, G.3
  • 33
    • 0032960948 scopus 로고    scopus 로고
    • Leukemia inhibitory factor, interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injury
    • Gadient, R.A., Patterson, P.H., Leukemia inhibitory factor, interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injury. Stem Cells 17 (1999), 127–137.
    • (1999) Stem Cells , vol.17 , pp. 127-137
    • Gadient, R.A.1    Patterson, P.H.2
  • 34
    • 0036894360 scopus 로고    scopus 로고
    • Interleukin-6 induces cellular insulin resistance in hepatocytes
    • Senn, J.J., Klover, P.J., Nowak, I.A., et al. Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes, 51, 2002, 3391.
    • (2002) Diabetes , vol.51 , pp. 3391
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3
  • 35
    • 0036731485 scopus 로고    scopus 로고
    • STATs: transcriptional control and biological impact
    • Levy, D.E., Darnell, J.E., STATs: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3 (2002), 651–662.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell, J.E.2
  • 36
    • 0041677606 scopus 로고    scopus 로고
    • Principles of interleukin (IL)-6-type cytokine signalling and its regulation
    • Heinrich, P.C., Behrmann, I., Haan, S., et al. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 374 (2003), 1–20.
    • (2003) Biochem J , vol.374 , pp. 1-20
    • Heinrich, P.C.1    Behrmann, I.2    Haan, S.3
  • 37
    • 84869797922 scopus 로고    scopus 로고
    • IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6
    • Rose-John, S., IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6. Int J Biol Sci 8 (2012), 1237–1247.
    • (2012) Int J Biol Sci , vol.8 , pp. 1237-1247
    • Rose-John, S.1
  • 38
    • 0035164602 scopus 로고    scopus 로고
    • The soluble interleukin 6 receptor: mechanisms of production and implications in disease
    • Jones, S.A., Horiuchi, S., Topley, N., et al. The soluble interleukin 6 receptor: mechanisms of production and implications in disease. FASEB J 15 (2001), 43–58.
    • (2001) FASEB J , vol.15 , pp. 43-58
    • Jones, S.A.1    Horiuchi, S.2    Topley, N.3
  • 39
    • 13244267455 scopus 로고    scopus 로고
    • Osteoclast-derived activity in the coupling of bone formation to resorption
    • Martin, T.J., Sims, N.A., Osteoclast-derived activity in the coupling of bone formation to resorption. Trends Mol Med 11 (2005), 76–81.
    • (2005) Trends Mol Med , vol.11 , pp. 76-81
    • Martin, T.J.1    Sims, N.A.2
  • 40
    • 84952719967 scopus 로고    scopus 로고
    • Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia
    • Shilo, V., Ben Dov, I.Z., Nechama, M., et al. Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia. FASEB J 29 (2015), 3964–3976.
    • (2015) FASEB J , vol.29 , pp. 3964-3976
    • Shilo, V.1    Ben Dov, I.Z.2    Nechama, M.3
  • 41
    • 85019449771 scopus 로고    scopus 로고
    • Klotho expression in long bones regulates FGF23 production during renal failure
    • Kaludjerovic, J., Komaba, H., Sato, T., et al. Klotho expression in long bones regulates FGF23 production during renal failure. FASEB J 31 (2017), 2050–2064.
    • (2017) FASEB J , vol.31 , pp. 2050-2064
    • Kaludjerovic, J.1    Komaba, H.2    Sato, T.3
  • 42
    • 34248512085 scopus 로고    scopus 로고
    • Mineralized tissue cells are a principal source of FGF23
    • Yoshiko, Y., Wang, H., Minamizaki, T., et al. Mineralized tissue cells are a principal source of FGF23. Bone 40 (2007), 1565–1573.
    • (2007) Bone , vol.40 , pp. 1565-1573
    • Yoshiko, Y.1    Wang, H.2    Minamizaki, T.3
  • 43
    • 85015743972 scopus 로고    scopus 로고
    • Kidney fibroblast growth factor 23 does not contribute to elevation of its circulating levels in uremia
    • Mace, M.L., Gravesen, E., Nordholm, A., et al. Kidney fibroblast growth factor 23 does not contribute to elevation of its circulating levels in uremia. Kidney Int 92 (2017), 165–178.
    • (2017) Kidney Int , vol.92 , pp. 165-178
    • Mace, M.L.1    Gravesen, E.2    Nordholm, A.3
  • 44
    • 84878242969 scopus 로고    scopus 로고
    • A novel model of adenine-induced tubulointerstitial nephropathy in mice
    • Jia, T., Olauson, H., Lindberg, K., et al. A novel model of adenine-induced tubulointerstitial nephropathy in mice. BMC Nephrol, 14, 2013, 116.
    • (2013) BMC Nephrol , vol.14 , pp. 116
    • Jia, T.1    Olauson, H.2    Lindberg, K.3
  • 45
    • 0031828429 scopus 로고    scopus 로고
    • The chemokine interleukin-8 regulates parathyroid secretion
    • Angeletti, R.H., D'Amico, T., Ashok, S., et al. The chemokine interleukin-8 regulates parathyroid secretion. J Bone Miner Res 13 (1998), 1232–1237.
    • (1998) J Bone Miner Res , vol.13 , pp. 1232-1237
    • Angeletti, R.H.1    D'Amico, T.2    Ashok, S.3
  • 47
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    • Liu, F., Song, Y., Liu, D., Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 6 (1999), 1258–1266.
    • (1999) Gene Ther , vol.6 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 48
    • 85008351008 scopus 로고    scopus 로고
    • Ironing out the cross talk between FGF23 and inflammation
    • David, V., Francis, C., Babitt, J.L., Ironing out the cross talk between FGF23 and inflammation. Am J Physiol Renal Physiol 312 (2017), F1–F8.
    • (2017) Am J Physiol Renal Physiol , vol.312 , pp. F1-F8
    • David, V.1    Francis, C.2    Babitt, J.L.3
  • 49
    • 84959894121 scopus 로고    scopus 로고
    • FGF23 signaling impairs neutrophil recruitment and host defense during CKD
    • Rossaint, J., Oehmichen, J., Van Aken, H., et al. FGF23 signaling impairs neutrophil recruitment and host defense during CKD. J Clin Invest 126 (2016), 962–974.
    • (2016) J Clin Invest , vol.126 , pp. 962-974
    • Rossaint, J.1    Oehmichen, J.2    Van Aken, H.3
  • 50
    • 0033740853 scopus 로고    scopus 로고
    • Differential anti-inflammatory and anti-oxidative effects of dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation
    • Rocksén, D., Lilliehöök, B., Larsson, R., et al. Differential anti-inflammatory and anti-oxidative effects of dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation. Clin Exp Immunol 122 (2000), 249–256.
    • (2000) Clin Exp Immunol , vol.122 , pp. 249-256
    • Rocksén, D.1    Lilliehöök, B.2    Larsson, R.3
  • 51
    • 84981263305 scopus 로고    scopus 로고
    • Phosphorylation of ribosomal protein S6 mediates mammalian target of rapamycin complex 1-induced parathyroid cell proliferation in secondary hyperparathyroidism
    • Volovelsky, O., Cohen, G., Kenig, A., et al. Phosphorylation of ribosomal protein S6 mediates mammalian target of rapamycin complex 1-induced parathyroid cell proliferation in secondary hyperparathyroidism. J Am Soc Nephrol 27 (2016), 1091–1101.
    • (2016) J Am Soc Nephrol , vol.27 , pp. 1091-1101
    • Volovelsky, O.1    Cohen, G.2    Kenig, A.3
  • 52
    • 85040581451 scopus 로고    scopus 로고
    • The JAK1/2 inhibitor ruxolitinib reverses interleukin-6-mediated suppression of drug detoxifying proteins in cultured human hepatocytes
    • Febvre-James, M., Bruyere, A., Le Vee, M., et al. The JAK1/2 inhibitor ruxolitinib reverses interleukin-6-mediated suppression of drug detoxifying proteins in cultured human hepatocytes. Drug Metab Dispos 46 (2018), 131–140.
    • (2018) Drug Metab Dispos , vol.46 , pp. 131-140
    • Febvre-James, M.1    Bruyere, A.2    Le Vee, M.3
  • 53
    • 33646367420 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D
    • Liu, S., Tang, W., Zhou, J., et al. Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 17 (2006), 1305–1315.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1305-1315
    • Liu, S.1    Tang, W.2    Zhou, J.3


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