Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production

Kidney International

Volumn 89, Issue 1, 2016, Pages 135-146

  David, Valentin ^a   Martin, Aline ^a   Isakova, Tamara ^a   Spaulding, Christina ^a   Qi, Lixin ^a   Ramirez, Veronica ^a   Zumbrennen Bullough, Kimberly B ^b   Sun, Chia Chi ^b   Lin, Herbert Y ^b   Babitt, Jodie L ^b   Wolf, Myles ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

anemia; bone; FGF23; hypoxia; inflammation; mineral metabolism

Indexed keywords

FIBROBLAST GROWTH FACTOR 23; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; IRON; MESSENGER RNA; AUTOANTIGEN; COLLAGEN TYPE 4; DEFEROXAMINE; FIBROBLAST GROWTH FACTOR; HIF1A PROTEIN, MOUSE; SIDEROPHORE; TYPE IV COLLAGEN ALPHA3 CHAIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRUCELLA ABORTUS; CARBOXY TERMINAL SEQUENCE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; GENE EXPRESSION; INFLAMMATION; IRON BLOOD LEVEL; IRON DEFICIENCY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OSTEOCYTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CLEAVAGE; PROTEIN SYNTHESIS REGULATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; WILD TYPE MOUSE; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; CHRONIC KIDNEY FAILURE; DEFICIENCY; DRUG EFFECTS; FEMUR; GENETIC TRANSCRIPTION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM;

ANIMALS; AUTOANTIGENS; CELL LINE; COLLAGEN TYPE IV; DEFEROXAMINE; FEMUR; FIBROBLAST GROWTH FACTORS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; INTERLEUKIN-1BETA; IRON; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RENAL INSUFFICIENCY, CHRONIC; RNA, MESSENGER; SIDEROPHORES; TRANSCRIPTION, GENETIC;

EID: 84946130633     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2015.290     Document Type: Article

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