Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner

Journal of Natural Products

Volumn 81, Issue 5, 2018, Pages 1131-1142

  Eräsalo, Heikki ^a   Hämäläinen, Mari ^a   Leppänen, Tiina ^a   Mäki Opas, Ilari ^a   Laavola, Mirka ^a   Haavikko, Raisa ^b   Yli Kauhaluoma, Jari ^b   Moilanen, Eeva ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTIINFLAMMATORY AGENT; ASTRINGIN; DEXAMETHASONE; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOMETHYLPINOSYLVIN; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PICEATANNOL; PINOSYLVIN; PINOSYLVIN MONOALLYL ETHER; PINOSYLVIN MONOBENZYL ETHER; PINOSYLVIN MONOETHYL ETHER; PINOSYLVIN MONOISOBUTYL ETHER; PINOSYLVIN MONOPROPYL ETHER; POLYPHENOL DERIVATIVE; PROTEIN KINASE B; PTEROSTILBENE; RESVERATROL; RHAPONTIGENIN; RHAPONTIN; STILBENOID DERIVATIVE; UNCLASSIFIED DRUG; AUTACOID; BIOLOGICAL PRODUCT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARRAGEENAN-INDUCED PAW EDEMA; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG SYNTHESIS; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PI3K/AKT SIGNALING; ANIMAL; C57BL MOUSE; CELL LINE; DRUG EFFECT; INFLAMMATION; MALE; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL PRODUCTS; CELL LINE; CHEMOKINE CCL2; DOWN-REGULATION; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 85047530291     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/acs.jnatprod.7b00384     Document Type: Article

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