메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

Down-Regulation of Protein Kinase Cδ Inhibits Inducible Nitric Oxide Synthase Expression through IRF1

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 1BETA; L NIL; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN KINASE C DELTA; ROTTLERIN; SMALL INTERFERING RNA; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84872256730     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052741     Document Type: Article
Times cited : (16)

References (57)
  • 4
    • 79960014508 scopus 로고    scopus 로고
    • Nitric oxide, a janus-faced therapeutic target for diabetic microangiopathy-Friend or foe?
    • Yamagishi S, Matsui T, (2011) Nitric oxide, a janus-faced therapeutic target for diabetic microangiopathy-Friend or foe? Pharmacol Res 64: 187-194.
    • (2011) Pharmacol Res , vol.64 , pp. 187-194
    • Yamagishi, S.1    Matsui, T.2
  • 5
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: structure, function and inhibition
    • Alderton WK, Cooper CE, Knowles RG, (2001) Nitric oxide synthases: structure, function and inhibition. Biochem J 357: 593-615.
    • (2001) Biochem J , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 6
    • 77954624383 scopus 로고    scopus 로고
    • Regulation of the expression of inducible nitric oxide synthase
    • Pautz A, Art J, Hahn S, Nowag S, Voss C, et al. (2010) Regulation of the expression of inducible nitric oxide synthase. Nitric Oxide 23: 75-93.
    • (2010) Nitric Oxide , vol.23 , pp. 75-93
    • Pautz, A.1    Art, J.2    Hahn, S.3    Nowag, S.4    Voss, C.5
  • 7
    • 0028348307 scopus 로고
    • Requirement for transcription factor IRF-1 in NO synthase induction in macrophages
    • Kamijo R, Harada H, Matsuyama T, Bosland M, Gerecitano J, et al. (1994) Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 263: 1612-1615.
    • (1994) Science , vol.263 , pp. 1612-1615
    • Kamijo, R.1    Harada, H.2    Matsuyama, T.3    Bosland, M.4    Gerecitano, J.5
  • 8
    • 0027939931 scopus 로고
    • Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase
    • Xie QW, Kashiwabara Y, Nathan C, (1994) Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J Biol Chem 269: 4705-4708.
    • (1994) J Biol Chem , vol.269 , pp. 4705-4708
    • Xie, Q.W.1    Kashiwabara, Y.2    Nathan, C.3
  • 9
    • 0030838532 scopus 로고    scopus 로고
    • Attenuation of nitric oxide synthase induction in IRF-1-deficient glial cells
    • Fujimura M, Tominaga T, Kato I, Takasawa S, Kawase M, et al. (1997) Attenuation of nitric oxide synthase induction in IRF-1-deficient glial cells. Brain Res 759: 247-250.
    • (1997) Brain Res , vol.759 , pp. 247-250
    • Fujimura, M.1    Tominaga, T.2    Kato, I.3    Takasawa, S.4    Kawase, M.5
  • 10
    • 0035067108 scopus 로고    scopus 로고
    • Requirement for STAT1 in LPS-induced gene expression in macrophages
    • Ohmori Y, Hamilton TA, (2001) Requirement for STAT1 in LPS-induced gene expression in macrophages. J Leukoc Biol 69: 598-604.
    • (2001) J Leukoc Biol , vol.69 , pp. 598-604
    • Ohmori, Y.1    Hamilton, T.A.2
  • 11
    • 0031022516 scopus 로고    scopus 로고
    • An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide
    • Gao J, Morrison DC, Parmely TJ, Russell SW, Murphy WJ, (1997) An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide. J Biol Chem 272: 1226-1230.
    • (1997) J Biol Chem , vol.272 , pp. 1226-1230
    • Gao, J.1    Morrison, D.C.2    Parmely, T.J.3    Russell, S.W.4    Murphy, W.J.5
  • 12
    • 33646169337 scopus 로고    scopus 로고
    • Selective inhibitors of inducible nitric oxide synthase: potential agents for the treatment of inflammatory diseases?
    • Tinker AC, Wallace AV, (2006) Selective inhibitors of inducible nitric oxide synthase: potential agents for the treatment of inflammatory diseases? Curr Top Med Chem 6: 77-92.
    • (2006) Curr Top Med Chem , vol.6 , pp. 77-92
    • Tinker, A.C.1    Wallace, A.V.2
  • 13
    • 1542619344 scopus 로고    scopus 로고
    • Protein kinase C isozymes as potential targets for anticancer therapy
    • Hofmann J, (2004) Protein kinase C isozymes as potential targets for anticancer therapy. Curr Cancer Drug Targets 4: 125-146.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 125-146
    • Hofmann, J.1
  • 14
    • 4444245423 scopus 로고    scopus 로고
    • Protein kinase C and beyond
    • Spitaler M, Cantrell DA, (2004) Protein kinase C and beyond. Nat Immunol 5: 785-790.
    • (2004) Nat Immunol , vol.5 , pp. 785-790
    • Spitaler, M.1    Cantrell, D.A.2
  • 15
    • 10944238407 scopus 로고    scopus 로고
    • Distinctive activation mechanisms and functions for protein kinase Cdelta
    • Steinberg SF, (2004) Distinctive activation mechanisms and functions for protein kinase Cdelta. Biochem J 384: 449-459.
    • (2004) Biochem J , vol.384 , pp. 449-459
    • Steinberg, S.F.1
  • 16
    • 43349100127 scopus 로고    scopus 로고
    • Protein kinase C isozymes as potential therapeutic targets in immune disorders
    • Lee MR, Duan W, Tan SL, (2008) Protein kinase C isozymes as potential therapeutic targets in immune disorders. Expert Opin Ther Targets 12: 535-552.
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 535-552
    • Lee, M.R.1    Duan, W.2    Tan, S.L.3
  • 17
    • 0035179086 scopus 로고    scopus 로고
    • Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice
    • Leitges M, Mayr M, Braun U, Mayr U, Li C, et al. (2001) Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice. J Clin Invest 108: 1505-1512.
    • (2001) J Clin Invest , vol.108 , pp. 1505-1512
    • Leitges, M.1    Mayr, M.2    Braun, U.3    Mayr, U.4    Li, C.5
  • 18
    • 0037171731 scopus 로고    scopus 로고
    • Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta
    • Miyamoto A, Nakayama K, Imaki H, Hirose S, Jiang Y, et al. (2002) Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta. Nature 416: 865-869.
    • (2002) Nature , vol.416 , pp. 865-869
    • Miyamoto, A.1    Nakayama, K.2    Imaki, H.3    Hirose, S.4    Jiang, Y.5
  • 21
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM, (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 22
    • 73649106499 scopus 로고    scopus 로고
    • Inhibition of protein kinase Cdelta reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages
    • Leppänen T, Jalonen U, Korhonen R, Tuominen RK, Moilanen E, (2010) Inhibition of protein kinase Cdelta reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages. Eur J Pharmacol 628: 220-225.
    • (2010) Eur J Pharmacol , vol.628 , pp. 220-225
    • Leppänen, T.1    Jalonen, U.2    Korhonen, R.3    Tuominen, R.K.4    Moilanen, E.5
  • 23
    • 33645542619 scopus 로고    scopus 로고
    • Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages
    • Salonen T, Sareila O, Jalonen U, Kankaanranta H, Tuominen R, et al. (2006) Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages. Br J Pharmacol 147: 790-799.
    • (2006) Br J Pharmacol , vol.147 , pp. 790-799
    • Salonen, T.1    Sareila, O.2    Jalonen, U.3    Kankaanranta, H.4    Tuominen, R.5
  • 24
    • 0034687690 scopus 로고    scopus 로고
    • Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells
    • Felley-Bosco E, Bender FC, Courjault-Gautier F, Bron C, Quest AF, (2000) Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells. Proc Natl Acad Sci U S A 97: 14334-14339.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 14334-14339
    • Felley-Bosco, E.1    Bender, F.C.2    Courjault-Gautier, F.3    Bron, C.4    Quest, A.F.5
  • 25
    • 0035968305 scopus 로고    scopus 로고
    • Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway
    • Musial A, Eissa NT, (2001) Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway. J Biol Chem 276: 24268-24273.
    • (2001) J Biol Chem , vol.276 , pp. 24268-24273
    • Musial, A.1    Eissa, N.T.2
  • 26
    • 36448936446 scopus 로고    scopus 로고
    • PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages
    • Paukkeri EL, Leppänen T, Sareila O, Vuolteenaho K, Kankaanranta H, et al. (2007) PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages. Br J Pharmacol 152: 1081-1091.
    • (2007) Br J Pharmacol , vol.152 , pp. 1081-1091
    • Paukkeri, E.L.1    Leppänen, T.2    Sareila, O.3    Vuolteenaho, K.4    Kankaanranta, H.5
  • 27
    • 0036765329 scopus 로고    scopus 로고
    • Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages
    • Korhonen R, Lahti A, Hämäläinen M, Kankaanranta H, Moilanen E, (2002) Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages. Mol Pharmacol 62: 698-704.
    • (2002) Mol Pharmacol , vol.62 , pp. 698-704
    • Korhonen, R.1    Lahti, A.2    Hämäläinen, M.3    Kankaanranta, H.4    Moilanen, E.5
  • 28
    • 0345547431 scopus 로고    scopus 로고
    • Regulation of the expression of inducible nitric oxide synthase
    • Kleinert H, Schwarz PM, Förstermann U, (2003) Regulation of the expression of inducible nitric oxide synthase. Biol Chem 384: 1343-1364.
    • (2003) Biol Chem , vol.384 , pp. 1343-1364
    • Kleinert, H.1    Schwarz, P.M.2    Förstermann, U.3
  • 29
    • 0042844654 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages
    • Lahti A, Jalonen U, Kankaanranta H, Moilanen E, (2003) c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages. Mol Pharmacol 64: 308-315.
    • (2003) Mol Pharmacol , vol.64 , pp. 308-315
    • Lahti, A.1    Jalonen, U.2    Kankaanranta, H.3    Moilanen, E.4
  • 30
    • 34247546617 scopus 로고    scopus 로고
    • Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase
    • Korhonen R, Linker K, Pautz A, Förstermann U, Moilanen E, et al. (2007) Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase. Mol Pharmacol 71: 1427-1434.
    • (2007) Mol Pharmacol , vol.71 , pp. 1427-1434
    • Korhonen, R.1    Linker, K.2    Pautz, A.3    Förstermann, U.4    Moilanen, E.5
  • 31
    • 0001378811 scopus 로고    scopus 로고
    • Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene
    • Gao JJ, Filla MB, Fultz MJ, Vogel SN, Russell SW, et al. (1998) Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene. J Immunol 161: 4803-4810.
    • (1998) J Immunol , vol.161 , pp. 4803-4810
    • Gao, J.J.1    Filla, M.B.2    Fultz, M.J.3    Vogel, S.N.4    Russell, S.W.5
  • 32
    • 0030669553 scopus 로고    scopus 로고
    • Molecular mechanisms regulating induction of interleukin-6 gene transcription by interferon-gamma
    • Faggioli L, Merola M, Hiscott J, Furia A, Monese R, et al. (1997) Molecular mechanisms regulating induction of interleukin-6 gene transcription by interferon-gamma. Eur J Immunol 27: 3022-3030.
    • (1997) Eur J Immunol , vol.27 , pp. 3022-3030
    • Faggioli, L.1    Merola, M.2    Hiscott, J.3    Furia, A.4    Monese, R.5
  • 33
    • 0029763960 scopus 로고    scopus 로고
    • Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation
    • Salvemini D, Wang ZQ, Wyatt PS, Bourdon DM, Marino MH, et al. (1996) Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br J Pharmacol 118: 829-838.
    • (1996) Br J Pharmacol , vol.118 , pp. 829-838
    • Salvemini, D.1    Wang, Z.Q.2    Wyatt, P.S.3    Bourdon, D.M.4    Marino, M.H.5
  • 34
    • 0031952104 scopus 로고    scopus 로고
    • A comparison of the effects of L-NAME, 7-NI and L-NIL on carrageenan-induced hindpaw oedema and NOS activity
    • Handy RL, Moore PK, (1998) A comparison of the effects of L-NAME, 7-NI and L-NIL on carrageenan-induced hindpaw oedema and NOS activity. Br J Pharmacol 123: 1119-1126.
    • (1998) Br J Pharmacol , vol.123 , pp. 1119-1126
    • Handy, R.L.1    Moore, P.K.2
  • 36
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies SP, Reddy H, Caivano M, Cohen P, (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351: 95-105.
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 37
    • 36549040859 scopus 로고    scopus 로고
    • The selectivity of protein kinase inhibitors: a further update
    • Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, et al. (2007) The selectivity of protein kinase inhibitors: a further update. Biochem J 408: 297-315.
    • (2007) Biochem J , vol.408 , pp. 297-315
    • Bain, J.1    Plater, L.2    Elliott, M.3    Shpiro, N.4    Hastie, C.J.5
  • 38
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw G, Kamen R, (1986) A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46: 659-667.
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 39
    • 0026729267 scopus 로고
    • Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme
    • Lowenstein CJ, Glatt CS, Bredt DS, Snyder SH, (1992) Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proc Natl Acad Sci U S A 89: 6711-6715.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 6711-6715
    • Lowenstein, C.J.1    Glatt, C.S.2    Bredt, D.S.3    Snyder, S.H.4
  • 40
    • 0026744830 scopus 로고
    • Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line
    • Lyons CR, Orloff GJ, Cunningham JM, (1992) Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J Biol Chem 267: 6370-6374.
    • (1992) J Biol Chem , vol.267 , pp. 6370-6374
    • Lyons, C.R.1    Orloff, G.J.2    Cunningham, J.M.3
  • 41
    • 34247546617 scopus 로고    scopus 로고
    • Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase
    • Korhonen R, Linker K, Pautz A, Förstermann U, Moilanen E, et al. (2007) Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase. Mol Pharmacol 71: 1427-1434.
    • (2007) Mol Pharmacol , vol.71 , pp. 1427-1434
    • Korhonen, R.1    Linker, K.2    Pautz, A.3    Förstermann, U.4    Moilanen, E.5
  • 42
    • 0029033981 scopus 로고
    • Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
    • Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, et al. (1995) Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science 268: 726-731.
    • (1995) Science , vol.268 , pp. 726-731
    • Fenteany, G.1    Standaert, R.F.2    Lane, W.S.3    Choi, S.4    Corey, E.J.5
  • 43
    • 0027368278 scopus 로고
    • Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide
    • Lowenstein CJ, Alley EW, Raval P, Snowman AM, Snyder SH, et al. (1993) Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc Natl Acad Sci U S A 90: 9730-9734.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 9730-9734
    • Lowenstein, C.J.1    Alley, E.W.2    Raval, P.3    Snowman, A.M.4    Snyder, S.H.5
  • 44
    • 72949109164 scopus 로고    scopus 로고
    • Protein kinase Cdelta and protein tyrosine kinase regulate peptidoglycan-induced nuclear factor-kappaB activation and inducible nitric oxide synthase expression in mouse peritoneal macrophages in vitro
    • Bhatt KH, Pandey RK, Dahiya Y, Sodhi A, (2010) Protein kinase Cdelta and protein tyrosine kinase regulate peptidoglycan-induced nuclear factor-kappaB activation and inducible nitric oxide synthase expression in mouse peritoneal macrophages in vitro. Mol Immunol 47: 861-870.
    • (2010) Mol Immunol , vol.47 , pp. 861-870
    • Bhatt, K.H.1    Pandey, R.K.2    Dahiya, Y.3    Sodhi, A.4
  • 45
    • 0031255318 scopus 로고    scopus 로고
    • The role of IFN regulatory factor-1 in synovitis and nitric oxide production
    • Shiraishi A, Dudler J, Lotz M, (1997) The role of IFN regulatory factor-1 in synovitis and nitric oxide production. J Immunol 159: 3549-3554.
    • (1997) J Immunol , vol.159 , pp. 3549-3554
    • Shiraishi, A.1    Dudler, J.2    Lotz, M.3
  • 46
    • 0037016711 scopus 로고    scopus 로고
    • Role of interferon regulatory factor-1 in double-stranded RNA-induced iNOS expression by mouse islets
    • Blair LA, Maggi LB Jr, Scarim AL, Corbett JA, (2002) Role of interferon regulatory factor-1 in double-stranded RNA-induced iNOS expression by mouse islets. J Biol Chem 277: 359-365.
    • (2002) J Biol Chem , vol.277 , pp. 359-365
    • Blair, L.A.1    Maggi Jr., L.B.2    Scarim, A.L.3    Corbett, J.A.4
  • 47
    • 0033561657 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide prevent inducible nitric oxide synthase transcription in macrophages by inhibiting NF-kappa B and IFN regulatory factor 1 activation
    • Delgado M, Munoz-Elias EJ, Gomariz RP, Ganea D, (1999) Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide prevent inducible nitric oxide synthase transcription in macrophages by inhibiting NF-kappa B and IFN regulatory factor 1 activation. J Immunol 162: 4685-4696.
    • (1999) J Immunol , vol.162 , pp. 4685-4696
    • Delgado, M.1    Munoz-Elias, E.J.2    Gomariz, R.P.3    Ganea, D.4
  • 48
    • 13344282731 scopus 로고    scopus 로고
    • Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
    • Meraz MA, White JM, Sheehan KC, Bach EA, Rodig SJ, et al. (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84: 431-442.
    • (1996) Cell , vol.84 , pp. 431-442
    • Meraz, M.A.1    White, J.M.2    Sheehan, K.C.3    Bach, E.A.4    Rodig, S.J.5
  • 49
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • Durbin JE, Hackenmiller R, Simon MC, Levy DE, (1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84: 443-450.
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 50
    • 0034948757 scopus 로고    scopus 로고
    • The interferon system and interferon regulatory factor transcription factors - studies from gene knockout mice
    • Sato M, Taniguchi T, Tanaka N, (2001) The interferon system and interferon regulatory factor transcription factors - studies from gene knockout mice. Cytokine Growth Factor Rev 12: 133-142.
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 133-142
    • Sato, M.1    Taniguchi, T.2    Tanaka, N.3
  • 52
    • 1942472504 scopus 로고    scopus 로고
    • Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation
    • Dugo L, Marzocco S, Mazzon E, Di Paola R, Genovese T, et al. (2004) Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation. Br J Pharmacol 141: 979-987.
    • (2004) Br J Pharmacol , vol.141 , pp. 979-987
    • Dugo, L.1    Marzocco, S.2    Mazzon, E.3    Di Paola, R.4    Genovese, T.5
  • 53
    • 3042566974 scopus 로고    scopus 로고
    • Selective inducible nitric oxide synthase (iNOS) inhibition attenuates remote acute lung injury in a model of ruptured abdominal aortic aneurysm
    • Harkin DW, Rubin BB, Romaschin A, Lindsay TF, (2004) Selective inducible nitric oxide synthase (iNOS) inhibition attenuates remote acute lung injury in a model of ruptured abdominal aortic aneurysm. J Surg Res 120: 230-241.
    • (2004) J Surg Res , vol.120 , pp. 230-241
    • Harkin, D.W.1    Rubin, B.B.2    Romaschin, A.3    Lindsay, T.F.4
  • 54
    • 23644449917 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase contributes to ventilator-induced lung injury
    • Peng X, Abdulnour RE, Sammani S, Ma SF, Han EJ, et al. (2005) Inducible nitric oxide synthase contributes to ventilator-induced lung injury. Am J Respir Crit Care Med 172: 470-479.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 470-479
    • Peng, X.1    Abdulnour, R.E.2    Sammani, S.3    Ma, S.F.4    Han, E.J.5
  • 55
    • 0035136429 scopus 로고    scopus 로고
    • Nitric oxide and nitrotyrosine in the lungs of patients with acute respiratory distress syndrome
    • Sittipunt C, Steinberg KP, Ruzinski JT, Myles C, Zhu S, et al. (2001) Nitric oxide and nitrotyrosine in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 163: 503-510.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 503-510
    • Sittipunt, C.1    Steinberg, K.P.2    Ruzinski, J.T.3    Myles, C.4    Zhu, S.5
  • 56
    • 79251544901 scopus 로고    scopus 로고
    • Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-delta (delta-PKC)
    • Kilpatrick LE, Standage SW, Li H, Raj NR, Korchak HM, et al. (2011) Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-delta (delta-PKC). J Leukoc Biol 89: 3-10.
    • (2011) J Leukoc Biol , vol.89 , pp. 3-10
    • Kilpatrick, L.E.1    Standage, S.W.2    Li, H.3    Raj, N.R.4    Korchak, H.M.5
  • 57
    • 0030741433 scopus 로고    scopus 로고
    • Multistage regulation of Th1-type immune responses by the transcription factor IRF-1
    • Taki S, Sato T, Ogasawara K, Fukuda T, Sato M, et al. (1997) Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. Immunity 6: 673-679.
    • (1997) Immunity , vol.6 , pp. 673-679
    • Taki, S.1    Sato, T.2    Ogasawara, K.3    Fukuda, T.4    Sato, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.