Anti-inflammatory mechanism of 15,16-epoxy-3α-hydroxylabda-8,13(16), 14-trien-7-one via inhibition of lps-induced multicellular signaling pathways

Journal of Natural Products

Volumn 75, Issue 1, 2012, Pages 67-71

  Khan, Salman ^a   Shehzad, Omer ^a   Jin, Hong Guang ^b   Woo, Eun Rhan ^b   Kang, Sam Sik ^a   Baek, Sa Wang ^a   Kim, Jinwoong ^a   Kim, Yeong Shik ^a  

^a Seoul National University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

15,16 EPOXY 3ALPHA HYDROXYLABDA 8,13 (16),14 TRIEN 7 ONE; CYCLOOXYGENASE 2; DITERPENE; DNA; I KAPPA B ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; LEONURUS JAPONICUS EXTRACT; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHORUS 32; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEIN P50; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LABELING; CELL STIMULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; DOWN REGULATION; ELECTROPHORETIC MOBILITY; ENZYME INHIBITION; IN VITRO STUDY; LEONURUS JAPONICUS; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHYTOCHEMISTRY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CYCLOOXYGENASE 2 INHIBITORS; DITERPENES; KOREA; LAMIACEAE; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR STRUCTURE; NF-KAPPA B; NITRIC OXIDE; PLANT ROOTS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA;

LEONURUS JAPONICUS;

EID: 84863015641     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np200666t     Document Type: Article

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