Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance

Immunity

Volumn 48, Issue 6, 2018, Pages 1245-1257.e9

  Campbell, Clarissa ^a,b   Dikiy, Stanislav ^a,b   Bhattarai, Shakti K ^c   Chinen, Takatoshi ^a   Matheis, Fanny ^d   Calafiore, Marco ^a   Hoyos, Beatrice ^a   Hanash, Alan ^a,e   Mucida, Daniel ^d   Bucci, Vanni ^c   Rudensky, Alexander Y ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Medical Center   (United States)

^c UNIVERSITY OF MASSACHUSETTS DARTMOUTH   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

extrathymic; host microbe interactions; microbiota; T reg cells

Indexed keywords

IMMUNOGLOBULIN A; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; RNA 16S; TRANSCRIPTION FACTOR FOXP3;

ADAPTIVE IMMUNITY; ALISTIPES; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEROIDES UNIFORMIS; BODY WEIGHT; BODY WEIGHT GAIN; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL LINE; COMMENSAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GOBLET CELL; HELICOBACTER HEPATICUS; IMMUNE RESPONSE; INTESTINE CRYPT; INTESTINE EPITHELIUM; INTESTINE FLORA; LACTOBACILLUS JOHNSONII; LAMINA PROPRIA; MALE; MAST CELL; METAGENOMICS; MICROBIAL COLONIZATION; MICROBIAL COMMUNITY; MICROBIAL CONSORTIUM; MICROORGANISM; MOUSE; MUCISPIRILLUM SCHAEDLERI; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; ANIMAL; IMMUNOLOGY; INTESTINE MUCOSA; MUCOSAL IMMUNITY;

ANIMALS; GASTROINTESTINAL MICROBIOME; HOST MICROBIAL INTERACTIONS; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; MICE; T-LYMPHOCYTES, REGULATORY;

EID: 85047295547     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2018.04.013     Document Type: Article

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