Wnt signaling regulates blood pressure by Downregulating a GSK-3β-mediated pathway to enhance insulin signaling in the central nervous system

Diabetes

Volumn 64, Issue 10, 2015, Pages 3413-3424

  Cheng, Pei Wen ^a   Chen, Ying Ying ^a   Cheng, Wen Han ^a   Lu, Pei Jung ^b   Chen, Hsin Hung ^c   Chen, Bo Rong ^a   Yeh, Tung Chen ^a   Sun, Gwo Ching ^b   Hsiao, Michael ^d   Tseng, Ching Jiunn ^a,c,e  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d GENOMICS RESEARCH CENTER   (Taiwan)

^e CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; NITRIC OXIDE; PROTEIN KINASE B; PROTEIN S6; WNT3A PROTEIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOWN REGULATION; ENZYME BINDING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IMMUNOBLOTTING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RAT; SOLITARY TRACT NUCLEUS; SYSTOLIC BLOOD PRESSURE; UPREGULATION; WNT SIGNALING PATHWAY; ANIMAL; BLOOD PRESSURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; RANDOMIZATION; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ANIMALS; BLOOD PRESSURE; DOWN-REGULATION; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MALE; NITRIC OXIDE; RANDOM ALLOCATION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION; SOLITARY NUCLEUS; WNT PROTEINS;

EID: 85047290468     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-1439     Document Type: Article

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