Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen

Nature Immunology

Volumn 19, Issue 6, 2018, Pages 617-624

  Rollenske, Tim ^a,b   Szijarto, Valeria ^c   Lukasiewicz, Jolanta ^d   Guachalla, Luis M ^c   Stojkovic, Katarina ^d   Hartl, Katharina ^c   Stulik, Lukas ^c   Kocher, Simone ^b   Lasitschka, Felix ^e   Al Saeedi, Mohammed ^e   Schröder Braunstein, Jutta ^e   Von Frankenberg, Moritz ^f   Gaebelein, Gereon ^g,h   Hoffmann, Peter ^e   Klein, Sabrina ^e   Heeg, Klaus ^e   Nagy, Eszter ^c   Nagy, Gabor ^c   Wardemann, Hedda ^a,b  

^a MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c Arsanis Biosciences   (Austria)

^d INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^f Department of Surgery   (Germany)

^g UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^h SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIUM LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 009; MONOCLONAL ANTIBODY 014; MONOCLONAL ANTIBODY 029; MONOCLONAL ANTIBODY 036; MONOCLONAL ANTIBODY 062; MONOCLONAL ANTIBODY 073; MONOCLONAL ANTIBODY 074; MONOCLONAL ANTIBODY 103; MONOCLONAL ANTIBODY 105; MONOCLONAL ANTIBODY 111; MONOCLONAL ANTIBODY 115; MONOCLONAL ANTIBODY 125; MONOCLONAL ANTIBODY 142; MONOCLONAL ANTIBODY 144; MONOCLONAL ANTIBODY 147; MONOCLONAL ANTIBODY 153; MONOCLONAL ANTIBODY 171; MONOCLONAL ANTIBODY 212; MONOCLONAL ANTIBODY 461; MONOCLONAL ANTIBODY 537; MONOCLONAL ANTIBODY 547; MONOCLONAL ANTIBODY 552; MONOCLONAL ANTIBODY 601; MONOCLONAL ANTIBODY 702; NEUTRALIZING ANTIBODY; O ANTIGEN; UNCLASSIFIED DRUG; UNINDEXED DRUG; BACTERIUM ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ARTICLE; BACTERIAL IMMUNITY; BLOOD; CONTROLLED STUDY; CROSS PROTECTION; DRUG CROSS REACTIVITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMORAL IMMUNITY; IN VIVO STUDY; INFECTION PREVENTION; INTESTINE CELL; INTESTINE FLORA; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MALE; MEMORY CELL; MICROBIAL DIVERSITY; MOUSE; NONHUMAN; NORMAL HUMAN; PLASMABLAST; PRIORITY JOURNAL; SEROTYPE; SOMATIC HYPERMUTATION; CROSS REACTION; IMMUNOLOGY;

ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CROSS REACTIONS; HUMANS; KLEBSIELLA PNEUMONIAE; O ANTIGENS;

EID: 85046895634     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/s41590-018-0106-2     Document Type: Article

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