Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection

Cell Metabolism

Volumn 27, Issue 5, 2018, Pages 988-1006.e7

  Tucey, Timothy M ^a   Verma, Jiyoti ^a   Harrison, Paul F ^a   Snelgrove, Sarah L ^a   Lo, Tricia L ^a   Scherer, Allison K ^b   Barugahare, Adele A ^a   Powell, David R ^a   Wheeler, Robert T ^b   Hickey, Michael J ^a   Beilharz, Traude H ^a   Naderer, Thomas ^a   Traven, Ana ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MAINE   (United States)

Author keywords

Candida albicans; fungal infection; GAL4; glucose homeostasis; glycolysis; immunometabolism; macrophage; TYE7; Warburg effect

Indexed keywords

ARGININE; CASPOFUNGIN; GALACTOSE; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUTAMINE; GLYOXYLIC ACID; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; ITACONIC ACID; LACTIC ACID; LEUCINE; MESSENGER RNA; METFORMIN; OLIGOMYCIN; OXYGEN; SERINE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEACHING; CANDIDIASIS; CARBON SOURCE; CELL DEATH; CELL KILLING; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; EX VIVO STUDY; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLYCOLYSIS; HOST PATHOGEN INTERACTION; HYPOGLYCEMIA; IMMUNOCOMPETENT CELL; IN VIVO STUDY; LIVE CELL IMAGING; MACROPHAGE ACTIVATION; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PHAGOCYTOSIS; PHAGOLYSOSOME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; SYSTEMIC MYCOSIS; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; C57BL MOUSE; CANDIDA ALBICANS; CANDIDEMIA; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; MACROPHAGE; METABOLISM; MICROBIOLOGY; MOUSE; PHYSIOLOGY;

ANIMALS; CANDIDA ALBICANS; CANDIDEMIA; CELL SURVIVAL; DISEASE MODELS, ANIMAL; GLYCOLYSIS; HOST-PATHOGEN INTERACTIONS; MACROPHAGES; MICE; MICE, INBRED C57BL;

EID: 85045572752     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2018.03.019     Document Type: Article

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