메뉴 건너뛰기




Volumn 20, Issue 5, 2018, Pages 1262-1279

Comparisons of diabetic retinopathy events associated with glucose-lowering drugs in patients with type 2 diabetes mellitus: A network meta-analysis

Author keywords

antidiabetic drug; diabetic retinopathy; network meta analysis type 2 diabetes

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACARBOSE; ALBIGLUTIDE; ALOGLIPTIN; ALPHA GLUCOSIDASE INHIBITOR; BIGUANIDE DERIVATIVE; CANAGLIFLOZIN; DAPAGLIFLOZIN; DIPEPTIDYL PEPTIDASE IV INHIBITOR; DULAGLUTIDE; EMPAGLIFLOZIN; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; HEMOGLOBIN A1C; INSULIN; INSULIN GLARGINE; LINAGLIPTIN; LIRAGLUTIDE; LIXISENATIDE; METFORMIN; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; SAXAGLIPTIN; SEMAGLUTIDE; SITAGLIPTIN; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SULFONYLUREA; SULFONYLUREA DERIVATIVE; UNINDEXED DRUG; ANTIDIABETIC AGENT; GLP1R PROTEIN, HUMAN; GLUCAGON LIKE PEPTIDE 1 RECEPTOR;

EID: 85045323644     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.13232     Document Type: Article
Times cited : (56)

References (76)
  • 2
    • 84874399232 scopus 로고    scopus 로고
    • Assessing progress in retinopathy outcomes in type 1 diabetes: comparing findings from the Wisconsin Diabetes Registry Study and the Wisconsin Epidemiologic Study of Diabetic Retinopathy
    • LeCaire TJ, Palta M, Klein R, Klein BE, Cruickshanks KJ. Assessing progress in retinopathy outcomes in type 1 diabetes: comparing findings from the Wisconsin Diabetes Registry Study and the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Diabetes Care. 2013;36:631-637.
    • (2013) Diabetes Care , vol.36 , pp. 631-637
    • LeCaire, T.J.1    Palta, M.2    Klein, R.3    Klein, B.E.4    Cruickshanks, K.J.5
  • 3
    • 34548087845 scopus 로고    scopus 로고
    • Management of diabetic retinopathy: a systematic review
    • Mohamed Q, Gillies MC, Wong TY. Management of diabetic retinopathy: a systematic review. JAMA. 2007;298:902-916.
    • (2007) JAMA , vol.298 , pp. 902-916
    • Mohamed, Q.1    Gillies, M.C.2    Wong, T.Y.3
  • 4
    • 0027370108 scopus 로고
    • Nathan DM, Genuth S et al. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group, Nathan DM, Genuth S et al. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 5
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
    • Stratton IM, Adler AI, Neil HA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000;321:405-412.
    • (2000) BMJ , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.3
  • 7
    • 85019750648 scopus 로고    scopus 로고
    • Diabetic retinopathy: a position statement by the American Diabetes Association
    • Solomon SD, Chew E, Duh EJ, et al. Diabetic retinopathy: a position statement by the American Diabetes Association. Diabetes Care. 2017;40:412-418.
    • (2017) Diabetes Care , vol.40 , pp. 412-418
    • Solomon, S.D.1    Chew, E.2    Duh, E.J.3
  • 8
    • 84994813253 scopus 로고    scopus 로고
    • Semaglutide and cardiovascular outcomes in patients with type 2 diabetes
    • Marso SP, Bain SC, Consoli A, et al. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med. 2016;375:1834-1844.
    • (2016) N Engl J Med , vol.375 , pp. 1834-1844
    • Marso, S.P.1    Bain, S.C.2    Consoli, A.3
  • 9
    • 62649174048 scopus 로고    scopus 로고
    • Glitazone use associated with diabetic macular edema
    • Fong DS, Contreras R. Glitazone use associated with diabetic macular edema. Am J Ophthalmol. 2009;147:583-586.
    • (2009) Am J Ophthalmol , vol.147 , pp. 583-586
    • Fong, D.S.1    Contreras, R.2
  • 10
    • 84863694353 scopus 로고    scopus 로고
    • Association between thiazolidinedione treatment and risk of macular edema among patients with type 2 diabetes
    • Idris I, Warren G, Donnelly R. Association between thiazolidinedione treatment and risk of macular edema among patients with type 2 diabetes. Arch Intern Med. 2012;172:1005-1011.
    • (2012) Arch Intern Med , vol.172 , pp. 1005-1011
    • Idris, I.1    Warren, G.2    Donnelly, R.3
  • 11
    • 84957586606 scopus 로고    scopus 로고
    • Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats
    • Takakura S, Toyoshi T, Hayashizaki Y, Takasu T. Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats. Life Sci. 2016;147:125-131.
    • (2016) Life Sci , vol.147 , pp. 125-131
    • Takakura, S.1    Toyoshi, T.2    Hayashizaki, Y.3    Takasu, T.4
  • 12
    • 84932084410 scopus 로고    scopus 로고
    • The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations
    • Hutton B, Salanti G, Caldwell DM, et al. The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med. 2015;162:777-784.
    • (2015) Ann Intern Med , vol.162 , pp. 777-784
    • Hutton, B.1    Salanti, G.2    Caldwell, D.M.3
  • 13
    • 84979895487 scopus 로고    scopus 로고
    • Empagliflozin and progression of kidney disease in type 2 diabetes
    • Wanner C, Inzucchi SE, Lachin JM, et al. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med. 2016;375:323-334.
    • (2016) N Engl J Med , vol.375 , pp. 323-334
    • Wanner, C.1    Inzucchi, S.E.2    Lachin, J.M.3
  • 14
    • 84978839381 scopus 로고    scopus 로고
    • Liraglutide and cardiovascular outcomes in type 2 diabetes
    • Marso SP, Daniels GH, Brown-Frandsen K, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2016;375:311-322.
    • (2016) N Engl J Med , vol.375 , pp. 311-322
    • Marso, S.P.1    Daniels, G.H.2    Brown-Frandsen, K.3
  • 15
    • 70049099036 scopus 로고    scopus 로고
    • Chapter 8: assessing risk of bias in included studies
    • In, Higgins J, Green S, eds., Updated March 2011., The Cochrane Collaboration, Accessed March 20, 2017
    • JPT H, Altman DG, Sterne AC. Chapter 8: assessing risk of bias in included studies. In: Higgins J, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions Version 510. Updated March 2011. The Cochrane Collaboration; 2011. http://handbook-5-1.cochrane.org/. Accessed March 20, 2017.
    • (2011) Cochrane Handbook for Systematic Reviews of Interventions Version 510
    • Jpt, H.1    Altman, D.G.2    Sterne, A.C.3
  • 16
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 17
    • 84875612338 scopus 로고    scopus 로고
    • Consistency and inconsistency in network meta-analysis: model estimation using multivariate meta-regression
    • White IR, Barrett JK, Jackson D, Higgins JP. Consistency and inconsistency in network meta-analysis: model estimation using multivariate meta-regression. Res Synth Methods. 2012;3:111-125.
    • (2012) Res Synth Methods , vol.3 , pp. 111-125
    • White, I.R.1    Barrett, J.K.2    Jackson, D.3    Higgins, J.P.4
  • 19
    • 61949136504 scopus 로고    scopus 로고
    • Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials
    • Keus F, Wetterslev J, Gluud C, Gooszen HG, van Laarhoven CJ. Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials. Am J Gastroenterol. 2009;104:546-551.
    • (2009) Am J Gastroenterol , vol.104 , pp. 546-551
    • Keus, F.1    Wetterslev, J.2    Gluud, C.3    Gooszen, H.G.4    van Laarhoven, C.J.5
  • 20
    • 85164560670 scopus 로고    scopus 로고
    • Indirect and mixed-treatment comparison, network, or multiple-treatments meta-analysis: many names, many benefits, many concerns for the next generation evidence synthesis tool
    • Salanti G. Indirect and mixed-treatment comparison, network, or multiple-treatments meta-analysis: many names, many benefits, many concerns for the next generation evidence synthesis tool. Res Synth Methods. 2012;3:80-97.
    • (2012) Res Synth Methods , vol.3 , pp. 80-97
    • Salanti, G.1
  • 21
    • 84864508284 scopus 로고    scopus 로고
    • Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews
    • Turner RM, Davey J, Clarke MJ, Thompson SG, Higgins JP. Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews. Int J Epidemiol. 2012;41:818-827.
    • (2012) Int J Epidemiol , vol.41 , pp. 818-827
    • Turner, R.M.1    Davey, J.2    Clarke, M.J.3    Thompson, S.G.4    Higgins, J.P.5
  • 23
    • 84875625927 scopus 로고    scopus 로고
    • Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies
    • Higgins JP, Jackson D, Barrett JK, Lu G, Ades AE, White IR. Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Methods. 2012;3:98-110.
    • (2012) Res Synth Methods , vol.3 , pp. 98-110
    • Higgins, J.P.1    Jackson, D.2    Barrett, J.K.3    Lu, G.4    Ades, A.E.5    White, I.R.6
  • 24
    • 84880287328 scopus 로고    scopus 로고
    • Using network meta-analysis to evaluate the existence of small-study effects in a network of interventions
    • Chaimani A, Salanti G. Using network meta-analysis to evaluate the existence of small-study effects in a network of interventions. Res Synth Methods. 2012;3:161-176.
    • (2012) Res Synth Methods , vol.3 , pp. 161-176
    • Chaimani, A.1    Salanti, G.2
  • 25
    • 85030448557 scopus 로고    scopus 로고
    • Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
    • Holman RR, Bethel MA, Mentz RJ, et al. Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2017;377:1228-1239.
    • (2017) N Engl J Med , vol.377 , pp. 1228-1239
    • Holman, R.R.1    Bethel, M.A.2    Mentz, R.J.3
  • 26
    • 84937053742 scopus 로고    scopus 로고
    • Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
    • Green JB, Bethel MA, Armstrong PW, et al. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2015;373:232-242.
    • (2015) N Engl J Med , vol.373 , pp. 232-242
    • Green, J.B.1    Bethel, M.A.2    Armstrong, P.W.3
  • 27
    • 84883745765 scopus 로고    scopus 로고
    • Alogliptin after acute coronary syndrome in patients with type 2 diabetes
    • White WB, Cannon CP, Heller SR, et al. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med. 2013;369:1327-1335.
    • (2013) N Engl J Med , vol.369 , pp. 1327-1335
    • White, W.B.1    Cannon, C.P.2    Heller, S.R.3
  • 28
    • 80053072352 scopus 로고    scopus 로고
    • Efficacy and safety of linagliptin in persons with type 2 diabetes inadequately controlled by a combination of metformin and sulphonylurea: a 24-week randomized study
    • Owens DR, Swallow R, Dugi KA, Woerle HJ. Efficacy and safety of linagliptin in persons with type 2 diabetes inadequately controlled by a combination of metformin and sulphonylurea: a 24-week randomized study. Diabet Med. 2011;28:1352-1361.
    • (2011) Diabet Med , vol.28 , pp. 1352-1361
    • Owens, D.R.1    Swallow, R.2    Dugi, K.A.3    Woerle, H.J.4
  • 29
    • 84883765959 scopus 로고    scopus 로고
    • Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
    • Scirica BM, Bhatt DL, Braunwald E, et al. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med. 2013;369:1317-1326.
    • (2013) N Engl J Med , vol.369 , pp. 1317-1326
    • Scirica, B.M.1    Bhatt, D.L.2    Braunwald, E.3
  • 30
    • 84885130771 scopus 로고    scopus 로고
    • Saxagliptin add-on therapy to insulin with or without metformin for type 2 diabetes mellitus: 52-week safety and efficacy
    • Barnett AH, Charbonnel B, Li J, Donovan M, Fleming D, Iqbal N. Saxagliptin add-on therapy to insulin with or without metformin for type 2 diabetes mellitus: 52-week safety and efficacy. Clin Drug Investig. 2013;33:707-717.
    • (2013) Clin Drug Investig , vol.33 , pp. 707-717
    • Barnett, A.H.1    Charbonnel, B.2    Li, J.3    Donovan, M.4    Fleming, D.5    Iqbal, N.6
  • 31
    • 84889857731 scopus 로고    scopus 로고
    • Effects of adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a ≥52-week randomized, double-blind study
    • Yki-Järvinen H, Rosenstock J, Duran-Garcia S, et al. Effects of adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a ≥52-week randomized, double-blind study. Diabetes Care. 2013;36:3875-3881.
    • (2013) Diabetes Care , vol.36 , pp. 3875-3881
    • Yki-Järvinen, H.1    Rosenstock, J.2    Duran-Garcia, S.3
  • 32
    • 84876785125 scopus 로고    scopus 로고
    • Efficacy and safety of sitagliptin versus glipizide in patients with type 2 diabetes and moderate-to-severe chronic renal insufficiency
    • Arjona Ferreira JC, Marre M, Barzilai N, et al. Efficacy and safety of sitagliptin versus glipizide in patients with type 2 diabetes and moderate-to-severe chronic renal insufficiency. Diabetes Care. 2013;36:1067-1073.
    • (2013) Diabetes Care , vol.36 , pp. 1067-1073
    • Arjona Ferreira, J.C.1    Marre, M.2    Barzilai, N.3
  • 33
    • 84878358313 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once-daily morning or evening injections in type 2 diabetes inadequately controlled on metformin (GetGoal-M)
    • Ahrén B, Leguizamo Dimas A, Miossec P, Saubadu S, Aronson R. Efficacy and safety of lixisenatide once-daily morning or evening injections in type 2 diabetes inadequately controlled on metformin (GetGoal-M). Diabetes Care. 2013;36:2543-2550.
    • (2013) Diabetes Care , vol.36 , pp. 2543-2550
    • Ahrén, B.1    Leguizamo Dimas, A.2    Miossec, P.3    Saubadu, S.4    Aronson, R.5
  • 34
    • 84953351574 scopus 로고    scopus 로고
    • Efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide (HARMONY 2): 52 week primary endpoint results from a randomised, placebo-controlled trial in patients with type 2 diabetes mellitus inadequately controlled with diet and exercise
    • Nauck MA, Stewart MW, Perkins C, et al. Efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide (HARMONY 2): 52 week primary endpoint results from a randomised, placebo-controlled trial in patients with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetologia. 2016;59:266-274.
    • (2016) Diabetologia , vol.59 , pp. 266-274
    • Nauck, M.A.1    Stewart, M.W.2    Perkins, C.3
  • 35
    • 84948740668 scopus 로고    scopus 로고
    • Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
    • Pfeffer MA, Claggett B, Diaz R, et al. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med. 2015;373:2247-2257.
    • (2015) N Engl J Med , vol.373 , pp. 2247-2257
    • Pfeffer, M.A.1    Claggett, B.2    Diaz, R.3
  • 36
    • 80053113861 scopus 로고    scopus 로고
    • Fifty-two-week, randomized, multicenter trial to compare the safety and efficacy of the novel glucagon-like peptide-1 analog liraglutide vs glibenclamide in patients with type 2 diabetes
    • Kaku K, Rasmussen MF, Nishida T, Seino Y. Fifty-two-week, randomized, multicenter trial to compare the safety and efficacy of the novel glucagon-like peptide-1 analog liraglutide vs glibenclamide in patients with type 2 diabetes. J Diabetes Investig. 2011;2:441-447.
    • (2011) J Diabetes Investig. , vol.2 , pp. 441-447
    • Kaku, K.1    Rasmussen, M.F.2    Nishida, T.3    Seino, Y.4
  • 37
    • 84892477577 scopus 로고    scopus 로고
    • Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial
    • Kovacs CS, Seshiah V, Swallow R, et al. Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial. Diabetes Obes Metab. 2014;16:147-158.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 147-158
    • Kovacs, C.S.1    Seshiah, V.2    Swallow, R.3
  • 38
    • 84884167643 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial
    • Cefalu WT, Leiter LA, Yoon KH, et al. Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial. Lancet. 2013;382:941-950.
    • (2013) Lancet , vol.382 , pp. 941-950
    • Cefalu, W.T.1    Leiter, L.A.2    Yoon, K.H.3
  • 39
    • 84908332537 scopus 로고    scopus 로고
    • Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial
    • EMPA-REG H2H-SU Trial Investigators
    • Ridderstråle M, Andersen KR, Zeller C, et al. EMPA-REG H2H-SU Trial InvestigatorsComparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014;2:691-700.
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 691-700
    • Ridderstråle, M.1    Andersen, K.R.2    Zeller, C.3
  • 40
    • 79955015666 scopus 로고    scopus 로고
    • Initial combination therapy with saxagliptin and metformin provides sustained glycaemic control and is well tolerated for up to 76 weeks
    • Pfützner A, Paz-Pacheco E, Allen E, Frederich R, Chen R, Investigators CV. Initial combination therapy with saxagliptin and metformin provides sustained glycaemic control and is well tolerated for up to 76 weeks. Diabetes Obes Metab. 2011;13:567-576.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 567-576
    • Pfützner, A.1    Paz-Pacheco, E.2    Allen, E.3    Frederich, R.4    Chen, R.5
  • 41
    • 84908179637 scopus 로고    scopus 로고
    • Efficacy and safety of the once-weekly GLP-1 receptor agonist albiglutide versus sitagliptin in patients with type 2 diabetes and renal impairment: a randomized phase III study
    • Leiter LA, Carr MC, Stewart M, et al. Efficacy and safety of the once-weekly GLP-1 receptor agonist albiglutide versus sitagliptin in patients with type 2 diabetes and renal impairment: a randomized phase III study. Diabetes Care. 2014;37:2723-2730.
    • (2014) Diabetes Care , vol.37 , pp. 2723-2730
    • Leiter, L.A.1    Carr, M.C.2    Stewart, M.3
  • 42
    • 84942256934 scopus 로고    scopus 로고
    • Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study
    • Araki E, Inagaki N, Tanizawa Y, Oura T, Takeuchi M, Imaoka T. Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study. Diabetes Obes Metab. 2015;17:994-1002.
    • (2015) Diabetes Obes Metab , vol.17 , pp. 994-1002
    • Araki, E.1    Inagaki, N.2    Tanizawa, Y.3    Oura, T.4    Takeuchi, M.5    Imaoka, T.6
  • 43
    • 84908164432 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptor agonist or bolus insulin with optimized basal insulin in type 2 diabetes
    • Diamant M, Nauck MA, Shaginian R, et al. Glucagon-like peptide 1 receptor agonist or bolus insulin with optimized basal insulin in type 2 diabetes. Diabetes Care. 2014;37:2763-2773.
    • (2014) Diabetes Care , vol.37 , pp. 2763-2773
    • Diamant, M.1    Nauck, M.A.2    Shaginian, R.3
  • 44
    • 84919772916 scopus 로고    scopus 로고
    • HARMONY 4: randomised clinical trial comparing once-weekly albiglutide and insulin glargine in patients with type 2 diabetes inadequately controlled with metformin with or without sulfonylurea
    • Weissman PN, Carr MC, Ye J, et al. HARMONY 4: randomised clinical trial comparing once-weekly albiglutide and insulin glargine in patients with type 2 diabetes inadequately controlled with metformin with or without sulfonylurea. Diabetologia. 2014;57:2475-2484.
    • (2014) Diabetologia , vol.57 , pp. 2475-2484
    • Weissman, P.N.1    Carr, M.C.2    Ye, J.3
  • 45
    • 67149146438 scopus 로고    scopus 로고
    • Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial
    • Home PD, Pocock SJ, Beck-Nielsen H, et al. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet. 2009;373:2125-2135.
    • (2009) Lancet , vol.373 , pp. 2125-2135
    • Home, P.D.1    Pocock, S.J.2    Beck-Nielsen, H.3
  • 47
    • 84990911512 scopus 로고    scopus 로고
    • Efficacy and safety of dapagliflozin in Asian patients with type 2 diabetes after metformin failure: a randomized controlled trial
    • Yang W, Han P, Min KW, et al. Efficacy and safety of dapagliflozin in Asian patients with type 2 diabetes after metformin failure: a randomized controlled trial. J Diabetes. 2016;8:796-808.
    • (2016) J Diabetes , vol.8 , pp. 796-808
    • Yang, W.1    Han, P.2    Min, K.W.3
  • 50
    • 84977567493 scopus 로고    scopus 로고
    • Combination therapy with liraglutide and insulin in Japanese patients with type 2 diabetes: a 36-week, randomized, double-blind, parallel-group trial
    • Seino Y, Kaneko S, Fukuda S, et al. Combination therapy with liraglutide and insulin in Japanese patients with type 2 diabetes: a 36-week, randomized, double-blind, parallel-group trial. J Diabetes Investig. 2016;7:565-573.
    • (2016) J Diabetes Investig , vol.7 , pp. 565-573
    • Seino, Y.1    Kaneko, S.2    Fukuda, S.3
  • 51
    • 85045350059 scopus 로고    scopus 로고
    • Safety and efficacy of albiglutide in type 2 diabetes. NCT00849056., Accessed March 15, 2017
    • Safety and efficacy of albiglutide in type 2 diabetes. NCT00849056. 2016. https://clinicaltrials.gov/ct2/show/NCT00849056. Accessed March 15, 2017.
    • (2016)
  • 52
    • 84899545131 scopus 로고    scopus 로고
    • Beneficial effects of once-daily lixisenatide on overall and postprandial glycemic levels without significant excess of hypoglycemia in type 2 diabetes inadequately controlled on a sulfonylurea with or without metformin (GetGoal-S)
    • Rosenstock J, Hanefeld M, Shamanna P, et al. Beneficial effects of once-daily lixisenatide on overall and postprandial glycemic levels without significant excess of hypoglycemia in type 2 diabetes inadequately controlled on a sulfonylurea with or without metformin (GetGoal-S). J Diabetes Complications. 2014;28:386-392.
    • (2014) J Diabetes Complications , vol.28 , pp. 386-392
    • Rosenstock, J.1    Hanefeld, M.2    Shamanna, P.3
  • 53
    • 84885331631 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P)
    • Pinget M, Goldenberg R, Niemoeller E, Muehlen-Bartmer I, Guo H, Aronson R. Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P). Diabetes Obes Metab. 2013;15:1000-1007.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 1000-1007
    • Pinget, M.1    Goldenberg, R.2    Niemoeller, E.3    Muehlen-Bartmer, I.4    Guo, H.5    Aronson, R.6
  • 54
    • 80053617078 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 analog liraglutide in combination with sulfonylurea safely improves blood glucose measures vs sulfonylurea monotherapy in Japanese patients with type 2 diabetes: results of a 52-week, randomized, multicenter trial
    • Seino Y, Rasmussen MF, Nishida T, Kaku K. Glucagon-like peptide-1 analog liraglutide in combination with sulfonylurea safely improves blood glucose measures vs sulfonylurea monotherapy in Japanese patients with type 2 diabetes: results of a 52-week, randomized, multicenter trial. J Diabetes Investig. 2011;2:280-286.
    • (2011) J Diabetes Investig , vol.2 , pp. 280-286
    • Seino, Y.1    Rasmussen, M.F.2    Nishida, T.3    Kaku, K.4
  • 55
    • 84904977278 scopus 로고    scopus 로고
    • Advancing basal insulin replacement in type 2 diabetes inadequately controlled with insulin glargine plus oral agents: a comparison of adding albiglutide, a weekly GLP-1 receptor agonist, versus thrice-daily prandial insulin lispro
    • Rosenstock J, Fonseca VA, Gross JL, et al. Advancing basal insulin replacement in type 2 diabetes inadequately controlled with insulin glargine plus oral agents: a comparison of adding albiglutide, a weekly GLP-1 receptor agonist, versus thrice-daily prandial insulin lispro. Diabetes Care. 2014;37:2317-2325.
    • (2014) Diabetes Care , vol.37 , pp. 2317-2325
    • Rosenstock, J.1    Fonseca, V.A.2    Gross, J.L.3
  • 56
    • 77952309372 scopus 로고    scopus 로고
    • Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial
    • Pratley RE, Nauck M, Bailey T, et al. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet. 2010;375:1447-1456.
    • (2010) Lancet , vol.375 , pp. 1447-1456
    • Pratley, R.E.1    Nauck, M.2    Bailey, T.3
  • 57
    • 84904963065 scopus 로고    scopus 로고
    • HARMONY 3: 104-week randomized, double-blind, placebo- and active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo, sitagliptin, and glimepiride in patients with type 2 diabetes taking metformin
    • HARMONY 3 Study Group
    • Ahrén B, Johnson SL, Stewart M, et al. HARMONY 3 Study GroupHARMONY 3: 104-week randomized, double-blind, placebo- and active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo, sitagliptin, and glimepiride in patients with type 2 diabetes taking metformin. Diabetes Care. 2014;37:2141-2148.
    • (2014) Diabetes Care , vol.37 , pp. 2141-2148
    • Ahrén, B.1    Johnson, S.L.2    Stewart, M.3
  • 58
    • 85065599284 scopus 로고    scopus 로고
    • Standards of medical care in diabetes – 2017
    • Association AD. Standards of medical care in diabetes – 2017. Diabetes Care. 2017;40(suppl):S1-S135.
    • (2017) Diabetes Care , vol.40 , pp. S1-S135
  • 59
    • 84903487864 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats
    • Goncalves A, Marques C, Leal E, et al. Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats. Biochim Biophys Acta. 2014;1842:1454-1463.
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 1454-1463
    • Goncalves, A.1    Marques, C.2    Leal, E.3
  • 60
    • 84859444000 scopus 로고    scopus 로고
    • Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood-retinal barrier in a type 2 diabetes animal model
    • Goncalves A, Leal E, Paiva A, et al. Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood-retinal barrier in a type 2 diabetes animal model. Diabetes Obes Metab. 2012;14:454-463.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 454-463
    • Goncalves, A.1    Leal, E.2    Paiva, A.3
  • 61
    • 84962147366 scopus 로고    scopus 로고
    • Topical administration of GLP-1 receptor agonists prevents retinal neurodegeneration in experimental diabetes
    • Hernandez C, Bogdanov P, Corraliza L, et al. Topical administration of GLP-1 receptor agonists prevents retinal neurodegeneration in experimental diabetes. Diabetes. 2016;65:172-187.
    • (2016) Diabetes , vol.65 , pp. 172-187
    • Hernandez, C.1    Bogdanov, P.2    Corraliza, L.3
  • 62
    • 84966340290 scopus 로고    scopus 로고
    • Protective effect of a GLP-1 analog on ischemia-reperfusion induced blood-retinal barrier breakdown and inflammation
    • Goncalves A, Lin CM, Muthusamy A, et al. Protective effect of a GLP-1 analog on ischemia-reperfusion induced blood-retinal barrier breakdown and inflammation. Invest Ophthalmol Vis Sci. 2016;57:2584-2592.
    • (2016) Invest Ophthalmol Vis Sci , vol.57 , pp. 2584-2592
    • Goncalves, A.1    Lin, C.M.2    Muthusamy, A.3
  • 63
    • 85026802542 scopus 로고    scopus 로고
    • Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes
    • Hernandez C, Bogdanov P, Sola-Adell C, et al. Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes. Diabetologia. 2017;60:2285-2298.
    • (2017) Diabetologia , vol.60 , pp. 2285-2298
    • Hernandez, C.1    Bogdanov, P.2    Sola-Adell, C.3
  • 64
    • 84892386243 scopus 로고    scopus 로고
    • Effects of saxagliptin on early microvascular changes in patients with type 2 diabetes
    • Ott C, Raff U, Schmidt S, et al. Effects of saxagliptin on early microvascular changes in patients with type 2 diabetes. Cardiovasc Diabetol. 2014;13:19.
    • (2014) Cardiovasc Diabetol , vol.13 , pp. 19
    • Ott, C.1    Raff, U.2    Schmidt, S.3
  • 65
    • 84875822603 scopus 로고    scopus 로고
    • Vildagliptin in addition to metformin improves retinal blood flow and erythrocyte deformability in patients with type 2 diabetes mellitus - results from an exploratory study
    • Berndt-Zipfel C, Michelson G, Dworak M, et al. Vildagliptin in addition to metformin improves retinal blood flow and erythrocyte deformability in patients with type 2 diabetes mellitus - results from an exploratory study. Cardiovasc Diabetol. 2013;12:59.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 59
    • Berndt-Zipfel, C.1    Michelson, G.2    Dworak, M.3
  • 66
    • 84983732337 scopus 로고    scopus 로고
    • GLP-1-based therapies have no microvascular effects in type 2 diabetes mellitus: an acute and 12-week randomized, double-blind, placebo-controlled trial
    • Smits MM, Tonneijck L, Muskiet MH, et al. GLP-1-based therapies have no microvascular effects in type 2 diabetes mellitus: an acute and 12-week randomized, double-blind, placebo-controlled trial. Arterioscler Thromb Vasc Biol. 2016;36:2125-2132.
    • (2016) Arterioscler Thromb Vasc Biol , vol.36 , pp. 2125-2132
    • Smits, M.M.1    Tonneijck, L.2    Muskiet, M.H.3
  • 67
    • 85019559864 scopus 로고    scopus 로고
    • GLP-1R as a target for the treatment of diabetic retinopathy: friend or foe?
    • Simo R, Hernandez C. GLP-1R as a target for the treatment of diabetic retinopathy: friend or foe? Diabetes. 2017;66:1453-1460.
    • (2017) Diabetes , vol.66 , pp. 1453-1460
    • Simo, R.1    Hernandez, C.2
  • 68
    • 84898919428 scopus 로고    scopus 로고
    • The impact of improved glycaemic control with GLP-1 receptor agonist therapy on diabetic retinopathy
    • Varadhan L, Humphreys T, Walker AB, Varughese GI. The impact of improved glycaemic control with GLP-1 receptor agonist therapy on diabetic retinopathy. Diabetes Res Clin Pract. 2014;103:e37-e39.
    • (2014) Diabetes Res Clin Pract , vol.103 , pp. e37-e39
    • Varadhan, L.1    Humphreys, T.2    Walker, A.B.3    Varughese, G.I.4
  • 70
    • 85013827882 scopus 로고    scopus 로고
    • A randomised study of the impact of the SGLT2 inhibitor dapagliflozin on microvascular and macrovascular circulation
    • Ott C, Jumar A, Striepe K, et al. A randomised study of the impact of the SGLT2 inhibitor dapagliflozin on microvascular and macrovascular circulation. Cardiovasc Diabetol. 2017;16:26.
    • (2017) Cardiovasc Diabetol , vol.16 , pp. 26
    • Ott, C.1    Jumar, A.2    Striepe, K.3
  • 71
    • 84908514103 scopus 로고    scopus 로고
    • Sodium glucose cotransport-2 inhibition and intrarenal RAS activity in people with type 1 diabetes
    • Cherney DZ, Perkins BA, Soleymanlou N, et al. Sodium glucose cotransport-2 inhibition and intrarenal RAS activity in people with type 1 diabetes. Kidney Int. 2014;86:1057-1058.
    • (2014) Kidney Int , vol.86 , pp. 1057-1058
    • Cherney, D.Z.1    Perkins, B.A.2    Soleymanlou, N.3
  • 72
    • 84925332778 scopus 로고    scopus 로고
    • Effects of RAS inhibitors on diabetic retinopathy: a systematic review and meta-analysis
    • Wang B, Wang F, Zhang Y, et al. Effects of RAS inhibitors on diabetic retinopathy: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2015;3:263-274.
    • (2015) Lancet Diabetes Endocrinol , vol.3 , pp. 263-274
    • Wang, B.1    Wang, F.2    Zhang, Y.3
  • 73
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • Group AC, Patel A, MacMahon S, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008;358:2560-2572.
    • (2008) N Engl J Med , vol.358 , pp. 2560-2572
    • Patel, A.1    MacMahon, S.2
  • 74
    • 69949166204 scopus 로고    scopus 로고
    • Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus: a randomised controlled trial
    • Beulens JW, Patel A, Vingerling JR, et al. Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus: a randomised controlled trial. Diabetologia. 2009;52:2027-2036.
    • (2009) Diabetologia , vol.52 , pp. 2027-2036
    • Beulens, J.W.1    Patel, A.2    Vingerling, J.R.3
  • 75
    • 77949294909 scopus 로고    scopus 로고
    • Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy
    • Ambrosius WT, Danis RP, Goff DC Jr, et al. Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy. Arch Ophthalmol. 2010;128:312-318.
    • (2010) Arch Ophthalmol , vol.128 , pp. 312-318
    • Ambrosius, W.T.1    Danis, R.P.2    Goff, D.C.3
  • 76
    • 85040365620 scopus 로고    scopus 로고
    • Lack of longitudinal association between thiazolidinediones and incidence and progression of diabetic eye disease: the ACCORD EYE Study
    • [Epub ahead of print]
    • Gower EW, Lovato JF, Ambrosius WT, et al. Lack of longitudinal association between thiazolidinediones and incidence and progression of diabetic eye disease: the ACCORD EYE Study. Am J Ophthalmol. 2017. https://doi.org/10.1016/j.ajo.2017.12.007 [Epub ahead of print].
    • (2017) Am J Ophthalmol
    • Gower, E.W.1    Lovato, J.F.2    Ambrosius, W.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.