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Volumn 25, Issue 2, 2018, Pages 406-420

A miR-20a/MAPK1/c-Myc regulatory feedback loop regulates breast carcinogenesis and chemoresistance

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA 20A; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; ANTINEOPLASTIC AGENT; MAPK1 PROTEIN, HUMAN; MICRORNA; MIRN20 MICRORNA, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1;

EID: 85045316983     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2017.176     Document Type: Article
Times cited : (79)

References (54)
  • 4
    • 84984588811 scopus 로고    scopus 로고
    • Consensus recommendations and review by an International Expert Panel on Interventions in Hepatocellular Carcinoma (EPOIHCC)
    • Park JW, Amarapurkar D, Chao Y, Chen PJ, Geschwind JF, Goh KL et al. Consensus recommendations and review by an International Expert Panel on Interventions in Hepatocellular Carcinoma (EPOIHCC). Liver Int 2013; 33: 327-337.
    • (2013) Liver Int , vol.33 , pp. 327-337
    • Park, J.W.1    Amarapurkar, D.2    Chao, Y.3    Chen, P.J.4    Geschwind, J.F.5    Goh, K.L.6
  • 5
    • 13644254794 scopus 로고    scopus 로고
    • Molecular mechanisms of drug resistance
    • Longley DB, Johnston PG. Molecular mechanisms of drug resistance. J Pathol 2005; 205: 275-292.
    • (2005) J Pathol , vol.205 , pp. 275-292
    • Longley, D.B.1    Johnston, P.G.2
  • 7
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 8
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 2004; 431: 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 9
    • 78249275505 scopus 로고    scopus 로고
    • MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders
    • Kim AH, Reimers M, Maher B, Williamson V, McMichael O, McClay JL et al. MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders. Schizophr Res 2010; 124: 183-191.
    • (2010) Schizophr Res , vol.124 , pp. 183-191
    • Kim, A.H.1    Reimers, M.2    Maher, B.3    Williamson, V.4    McMichael, O.5    McClay, J.L.6
  • 10
    • 84917710873 scopus 로고    scopus 로고
    • Targeting of miR34a-NOTCH1 axis reduced breast cancer stemness and chemoresistance
    • Park EY, Chang E, Lee EJ, Lee HW, Kang HG, Chun KH et al. Targeting of miR34a-NOTCH1 axis reduced breast cancer stemness and chemoresistance. Cancer Res 2014; 74: 7573-7582.
    • (2014) Cancer Res , vol.74 , pp. 7573-7582
    • Park, E.Y.1    Chang, E.2    Lee, E.J.3    Lee, H.W.4    Kang, H.G.5    Chun, K.H.6
  • 11
    • 84905365381 scopus 로고    scopus 로고
    • Down-regulation of miRNA-452 is associated with adriamycin-resistance in breast cancer cells
    • Hu Q, Gong JP, Li J, Zhong SL, Chen WX, Zhang JY et al. Down-regulation of miRNA-452 is associated with adriamycin-resistance in breast cancer cells. Asian Pac J Cancer Prev 2014; 15: 5137-5142.
    • (2014) Asian Pac J Cancer Prev , vol.15 , pp. 5137-5142
    • Hu, Q.1    Gong, J.P.2    Li, J.3    Zhong, S.L.4    Chen, W.X.5    Zhang, J.Y.6
  • 12
    • 84973369534 scopus 로고    scopus 로고
    • CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance
    • Li G, Wu X, Qian W, Cai H, Sun X, Zhang W et al. CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance. Cell Res 2016; 26: 655-673.
    • (2016) Cell Res , vol.26 , pp. 655-673
    • Li, G.1    Wu, X.2    Qian, W.3    Cai, H.4    Sun, X.5    Zhang, W.6
  • 13
    • 77954378366 scopus 로고    scopus 로고
    • MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
    • Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y et al. MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression. J Biol Chem 2010; 285: 21496-21507.
    • (2010) J Biol Chem , vol.285 , pp. 21496-21507
    • Zhou, M.1    Liu, Z.2    Zhao, Y.3    Ding, Y.4    Liu, H.5    Xi, Y.6
  • 14
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007; 129: 1401-1414.
    • (2007) Cell , vol.129 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3    Sewer, A.4    Iovino, N.5    Aravin, A.6
  • 15
    • 57749102609 scopus 로고    scopus 로고
    • Rare (new) entities of the breast and medullary carcinoma
    • Foschini MP, Eusebi V. Rare (new) entities of the breast and medullary carcinoma. Pathology 2009; 41: 48-56.
    • (2009) Pathology , vol.41 , pp. 48-56
    • Foschini, M.P.1    Eusebi, V.2
  • 17
    • 34250208031 scopus 로고    scopus 로고
    • Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity
    • Vincent-Salomon A, Gruel N, Lucchesi C, Macgrogan G, Dendale R, Sigal-Zafrani B et al. Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity. Breast Cancer Res 2007; 9: R24.
    • (2007) Breast Cancer Res , vol.9 , pp. R24
    • Vincent-Salomon, A.1    Gruel, N.2    Lucchesi, C.3    Macgrogan, G.4    Dendale, R.5    Sigal-Zafrani, B.6
  • 18
    • 84878259408 scopus 로고    scopus 로고
    • Different administration strategies with paclitaxel induce distinct phenotypes of multidrug resistance in breast cancer cells
    • Jiang D, Sui M, Zhong W, Huang Y, Fan W. Different administration strategies with paclitaxel induce distinct phenotypes of multidrug resistance in breast cancer cells. Cancer Lett 2013; 335: 404-411.
    • (2013) Cancer Lett , vol.335 , pp. 404-411
    • Jiang, D.1    Sui, M.2    Zhong, W.3    Huang, Y.4    Fan, W.5
  • 19
    • 84926520496 scopus 로고    scopus 로고
    • MiR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression
    • Mu W, Hu C, Zhang H, Qu Z, Cen J, Qiu Z et al. miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression. Cell Res 2015; 25: 477-495.
    • (2015) Cell Res , vol.25 , pp. 477-495
    • Mu, W.1    Hu, C.2    Zhang, H.3    Qu, Z.4    Cen, J.5    Qiu, Z.6
  • 20
    • 84896113173 scopus 로고    scopus 로고
    • Fulvestrant, a selective estrogen receptor down-regulator, sensitizes estrogen receptor negative breast tumors to chemotherapy
    • Jiang D, Huang Y, Han N, Xu M, Xu L, Zhou L et al. Fulvestrant, a selective estrogen receptor down-regulator, sensitizes estrogen receptor negative breast tumors to chemotherapy. Cancer Lett 2014; 346: 292-299.
    • (2014) Cancer Lett , vol.346 , pp. 292-299
    • Jiang, D.1    Huang, Y.2    Han, N.3    Xu, M.4    Xu, L.5    Zhou, L.6
  • 21
    • 84916919342 scopus 로고    scopus 로고
    • Fas signaling promotes chemoresistance in gastrointestinal cancer by up-regulating P-glycoprotein
    • Zheng H, Liu Z, Liu T, Cai Y, Wang Y, Lin S et al. Fas signaling promotes chemoresistance in gastrointestinal cancer by up-regulating P-glycoprotein. Oncotarget 2014; 5: 10763-10777.
    • (2014) Oncotarget , vol.5 , pp. 10763-10777
    • Zheng, H.1    Liu, Z.2    Liu, T.3    Cai, Y.4    Wang, Y.5    Lin, S.6
  • 22
    • 84865750870 scopus 로고    scopus 로고
    • Collagen/beta1 integrin signaling up-regulates the ABCC1/ MRP-1 transporter in an ERK/MAPK-dependent manner
    • El Azreq MA, Naci D, Aoudjit F. Collagen/beta1 integrin signaling up-regulates the ABCC1/ MRP-1 transporter in an ERK/MAPK-dependent manner. Mol Biol Cell 2012; 23: 3473-3484.
    • (2012) Mol Biol Cell , vol.23 , pp. 3473-3484
    • El Azreq, M.A.1    Naci, D.2    Aoudjit, F.3
  • 23
    • 84881605979 scopus 로고    scopus 로고
    • Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-kappaB and MAPK/ERK mediated YB-1 activity in A2780/T cells
    • Zhao BX, YB Sun, Wang SQ, Duan L, Huo QL, Ren F et al. Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-kappaB and MAPK/ERK mediated YB-1 activity in A2780/T cells. Plos ONE 2013; 8: e71071.
    • (2013) Plos ONE , vol.8 , pp. e71071
    • Zhao, B.X.1    Sun, Y.B.2    Wang, S.Q.3    Duan, L.4    Huo, Q.L.5    Ren, F.6
  • 25
    • 27544443219 scopus 로고    scopus 로고
    • Modulation of mitogen-activated protein kinase cascades by differentiation-1 protein: Acquired drug resistance of hormone independent prostate cancer cells
    • Lin JC, Chang SY, Hsieh DS, Lee CF, Yu DS. Modulation of mitogen-activated protein kinase cascades by differentiation-1 protein: acquired drug resistance of hormone independent prostate cancer cells. J Urol 2005; 174: 2022-2026.
    • (2005) J Urol , vol.174 , pp. 2022-2026
    • Lin, J.C.1    Chang, S.Y.2    Hsieh, D.S.3    Lee, C.F.4    Yu, D.S.5
  • 26
    • 70349220767 scopus 로고    scopus 로고
    • Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
    • Yan HL, Xue G, Mei Q, Wang YZ, Ding FX, Liu MF et al. Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J 2009; 28: 2719-2732.
    • (2009) EMBO J , vol.28 , pp. 2719-2732
    • Yan, H.L.1    Xue, G.2    Mei, Q.3    Wang, Y.Z.4    Ding, F.X.5    Liu, M.F.6
  • 28
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N Engl J Med 2008; 358: 1148-1159.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 29
    • 0037810249 scopus 로고    scopus 로고
    • Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: Potential targeting for therapeutic intervention
    • Chang F, Steelman LS, Lee JT, Shelton JG, Navolanic PM, Blalock WL et al. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. Leukemia 2003; 17: 1263-1293.
    • (2003) Leukemia , vol.17 , pp. 1263-1293
    • Chang, F.1    Steelman, L.S.2    Lee, J.T.3    Shelton, J.G.4    Navolanic, P.M.5    Blalock, W.L.6
  • 30
    • 20444479428 scopus 로고    scopus 로고
    • Mendell JT. C-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005; 435: 839-843.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3    Dang, C.V.4
  • 31
    • 84882832773 scopus 로고    scopus 로고
    • MiR-20a triggers metastasis of gallbladder carcinoma
    • Chang Y, Liu C, Yang J, Liu G, Feng F, Tang J et al. MiR-20a triggers metastasis of gallbladder carcinoma. J Hepatol 2013; 59: 518-527.
    • (2013) J Hepatol , vol.59 , pp. 518-527
    • Chang, Y.1    Liu, C.2    Yang, J.3    Liu, G.4    Feng, F.5    Tang, J.6
  • 32
    • 84876682827 scopus 로고    scopus 로고
    • MiR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation
    • Wang M, Gu H, Qian H, Zhu W, Zhao C, Zhang X et al. miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation. Eur J Cancer 2013; 49: 2010-2021.
    • (2013) Eur J Cancer , vol.49 , pp. 2010-2021
    • Wang, M.1    Gu, H.2    Qian, H.3    Zhu, W.4    Zhao, C.5    Zhang, X.6
  • 33
    • 84863121672 scopus 로고    scopus 로고
    • Kleinerman ES. MiR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression
    • Huang G, Nishimoto K, Zhou Z, Hughes D, Kleinerman ES. miR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression. Cancer Res 2012; 72: 908-916.
    • (2012) Cancer Res , vol.72 , pp. 908-916
    • Huang, G.1    Nishimoto, K.2    Zhou, Z.3    Hughes, D.4
  • 34
    • 84864550842 scopus 로고    scopus 로고
    • Suppression of CX43 expression by miR-20a in the progression of human prostate cancer
    • Li X, Pan JH, Song B, Xiong EQ, Chen ZW, Zhou ZS et al. Suppression of CX43 expression by miR-20a in the progression of human prostate cancer. Cancer Biol Ther 2012; 13: 890-898.
    • (2012) Cancer Biol Ther , vol.13 , pp. 890-898
    • Li, X.1    Pan, J.H.2    Song, B.3    Xiong, E.Q.4    Chen, Z.W.5    Zhou, Z.S.6
  • 35
    • 84925667016 scopus 로고    scopus 로고
    • MiR-20a promotes cervical cancer proliferation and metastasis in vitro and in vivo
    • Zhao S, Yao D, Chen J, Ding N, Ren F. MiR-20a promotes cervical cancer proliferation and metastasis in vitro and in vivo. PLoS ONE 2015; 10: e0120905.
    • (2015) PLoS ONE , vol.10 , pp. e0120905
    • Zhao, S.1    Yao, D.2    Chen, J.3    Ding, N.4    Ren, F.5
  • 36
    • 84979948983 scopus 로고    scopus 로고
    • MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4
    • Cheng D, Zhao S, Tang H, Zhang D, Sun H, Yu F et al. MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4. Oncotarget 2016; 7: 45199-45213.
    • (2016) Oncotarget , vol.7 , pp. 45199-45213
    • Cheng, D.1    Zhao, S.2    Tang, H.3    Zhang, D.4    Sun, H.5    Yu, F.6
  • 37
    • 84883135588 scopus 로고    scopus 로고
    • MicroRNA-17/20a functions to inhibit cell migration and can be used a prognostic marker in oral squamous cell carcinoma
    • Chang CC, Yang YJ, Li YJ, Chen ST, Lin BR, Wu TS et al. MicroRNA-17/20a functions to inhibit cell migration and can be used a prognostic marker in oral squamous cell carcinoma. Oral Oncol 2013; 49: 923-931.
    • (2013) Oral Oncol , vol.49 , pp. 923-931
    • Chang, C.C.1    Yang, Y.J.2    Li, Y.J.3    Chen, S.T.4    Lin, B.R.5    Wu, T.S.6
  • 38
    • 78650096337 scopus 로고    scopus 로고
    • MicroRNA-20a overexpression inhibited proliferation and metastasis of pancreatic carcinoma cells
    • Yan H, Wu J, Liu W, Zuo Y, Chen S, Zhang S et al. MicroRNA-20a overexpression inhibited proliferation and metastasis of pancreatic carcinoma cells. Hum Gene Therapy 2010; 21: 1723-1734.
    • (2010) Hum Gene Therapy , vol.21 , pp. 1723-1734
    • Yan, H.1    Wu, J.2    Liu, W.3    Zuo, Y.4    Chen, S.5    Zhang, S.6
  • 39
    • 85006200925 scopus 로고    scopus 로고
    • MicroRNA-17/20a impedes migration and invasion via TGF-beta/ITGB6 pathway in esophageal squamous cell carcinoma
    • Jing C, Ma G, Li X, Wu X, Huang F, Liu K et al. MicroRNA-17/20a impedes migration and invasion via TGF-beta/ITGB6 pathway in esophageal squamous cell carcinoma. Am J Cancer Res 2016; 6: 1549-1562.
    • (2016) Am J Cancer Res , vol.6 , pp. 1549-1562
    • Jing, C.1    Ma, G.2    Li, X.3    Wu, X.4    Huang, F.5    Liu, K.6
  • 40
    • 84857355139 scopus 로고    scopus 로고
    • Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer
    • Kim K, Chadalapaka G, Lee SO, Yamada D, Sastre-Garau X, Defossez PA et al. Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer. Oncogene 2012; 31: 1034-1044.
    • (2012) Oncogene , vol.31 , pp. 1034-1044
    • Kim, K.1    Chadalapaka, G.2    Lee, S.O.3    Yamada, D.4    Sastre-Garau, X.5    Defossez, P.A.6
  • 41
    • 49749086530 scopus 로고    scopus 로고
    • A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
    • Yu Z, Wang C, Wang M, Li Z, Casimiro MC, Liu M et al. A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol 2008; 182: 509-517.
    • (2008) J Cell Biol , vol.182 , pp. 509-517
    • Yu, Z.1    Wang, C.2    Wang, M.3    Li, Z.4    Casimiro, M.C.5    Liu, M.6
  • 42
    • 77952360640 scopus 로고    scopus 로고
    • MicroRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling
    • Yu Z, Willmarth NE, Zhou J, Katiyar S, Wang M, Liu Y et al. microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling. Proc Natl Acad Sci USA 2010; 107: 8231-8236.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8231-8236
    • Yu, Z.1    Willmarth, N.E.2    Zhou, J.3    Katiyar, S.4    Wang, M.5    Liu, Y.6
  • 43
    • 79951881614 scopus 로고    scopus 로고
    • Tang H. MiR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines
    • Chai H, Liu M, Tian R, Li X, Tang H. miR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines. Acta Biochim Biophys Sin (Shanghai) 2011; 43: 217-225.
    • (2011) Acta Biochim Biophys Sin (Shanghai) , vol.43 , pp. 217-225
    • Chai, H.1    Liu, M.2    Tian, R.3    Li, X.4
  • 44
    • 84905995986 scopus 로고    scopus 로고
    • Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM.-S
    • Weng H, Huang H, Dong B, Zhao P, Zhou H, Qu L. Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S. Cancer Res 2014; 74: 4409-4419.
    • (2014) Cancer Res , vol.74 , pp. 4409-4419
    • Weng, H.1    Huang, H.2    Dong, B.3    Zhao, P.4    Zhou, H.5    Qu, L.6
  • 45
    • 84988412562 scopus 로고    scopus 로고
    • MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene
    • Pu Y, Yi Q, Zhao F, Wang H, Cai W, Cai S. MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene. Cancer Cell Int 2016; 16: 64.
    • (2016) Cancer Cell Int , vol.16 , pp. 64
    • Pu, Y.1    Yi, Q.2    Zhao, F.3    Wang, H.4    Cai, W.5    Cai, S.6
  • 46
    • 84899581656 scopus 로고    scopus 로고
    • MiRNA 17 family regulates cisplatin-resistant and metastasis by targeting TGFbetaR2 in NSCLC
    • Jiang Z, Yin J, Fu W, Mo Y, Pan Y, Dai L et al. MiRNA 17 family regulates cisplatin-resistant and metastasis by targeting TGFbetaR2 in NSCLC. PLoS ONE 2014; 9: e94639.
    • (2014) PLoS ONE , vol.9 , pp. e94639
    • Jiang, Z.1    Yin, J.2    Fu, W.3    Mo, Y.4    Pan, Y.5    Dai, L.6
  • 47
    • 79751484450 scopus 로고    scopus 로고
    • Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma
    • Hou J, Lin L, Zhou W, Wang Z, Ding G, Dong Q et al. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 2011; 19: 232-243.
    • (2011) Cancer Cell , vol.19 , pp. 232-243
    • Hou, J.1    Lin, L.2    Zhou, W.3    Wang, Z.4    Ding, G.5    Dong, Q.6
  • 48
    • 84897468938 scopus 로고    scopus 로고
    • MiR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1
    • Yu Z, Xu Z, Disante G, Wright J, Wang M, Li Y et al. miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget 2014; 5: 1083-1090.
    • (2014) Oncotarget , vol.5 , pp. 1083-1090
    • Yu, Z.1    Xu, Z.2    Disante, G.3    Wright, J.4    Wang, M.5    Li, Y.6
  • 50
    • 34447321311 scopus 로고    scopus 로고
    • Inhibition of the mitogenactivated protein kinase pathway results in the down-regulation of P-glycoprotein
    • Katayama K, Yoshioka S, Tsukahara S, Mitsuhashi J, Sugimoto Y. Inhibition of the mitogenactivated protein kinase pathway results in the down-regulation of P-glycoprotein. Mol Cancer Ther 2007; 6: 2092-2102.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2092-2102
    • Katayama, K.1    Yoshioka, S.2    Tsukahara, S.3    Mitsuhashi, J.4    Sugimoto, Y.5
  • 53
    • 0035914258 scopus 로고    scopus 로고
    • Cross-talk between signalling pathways and the multidrug resistant protein MDR-1
    • Ding S, Chamberlain M, McLaren A, Goh L, Duncan I, Wolf CR. Cross-talk between signalling pathways and the multidrug resistant protein MDR-1. Br J Cancer 2001; 85: 1175-1184.
    • (2001) Br J Cancer , vol.85 , pp. 1175-1184
    • Ding, S.1    Chamberlain, M.2    McLaren, A.3    Goh, L.4    Duncan, I.5    Wolf, C.R.6
  • 54
    • 84902097349 scopus 로고    scopus 로고
    • MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression
    • Fang L, Li H, Wang L, Hu J, Jin T, Wang J et al. MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression. Oncotarget 2014; 5: 2974-2987.
    • (2014) Oncotarget , vol.5 , pp. 2974-2987
    • Fang, L.1    Li, H.2    Wang, L.3    Hu, J.4    Jin, T.5    Wang, J.6


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