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Volumn 23, Issue 17, 2012, Pages 3473-3484

Collagen/β1 integrin signaling up-regulates the ABCC1/MRP-1 transporter in an ERK/MAPK-dependent manner

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; BETA1 INTEGRIN; COLLAGEN; COLLAGEN RECEPTOR; DOXORUBICIN; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE; MULTIDRUG RESISTANCE PROTEIN 1; SMALL INTERFERING RNA;

EID: 84865750870     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-02-0132     Document Type: Article
Times cited : (56)

References (63)
  • 1
    • 33645038097 scopus 로고    scopus 로고
    • The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1
    • Abdul-Ghani R, Serra V, Gyorffy B, Jurchott K, Solf A, Dietel M, Schafer R (2006). The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1. Oncogene 25, 1743-1752.
    • (2006) Oncogene , vol.25 , pp. 1743-1752
    • Abdul-Ghani, R.1    Serra, V.2    Gyorffy, B.3    Jurchott, K.4    Solf, A.5    Dietel, M.6    Schafer, R.7
  • 2
    • 71049156626 scopus 로고    scopus 로고
    • ABCG2: The key to chemoresistance in cancer stem cells?
    • An Y, Ongkeko WM (2009). ABCG2: the key to chemoresistance in cancer stem cells? Expert Opin Drug Metab Toxicol 5, 1529-1542.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 1529-1542
    • An, Y.1    Ongkeko, W.M.2
  • 3
    • 33847660184 scopus 로고    scopus 로고
    • Modulatory effects of heparin on cellular accumulation and cytotoxicity of doxorubicin in MRP1-overexpressing HL60/doxo cells
    • Angelini A, Ciofani G, Baccante G, Di Febbo C, Carmine DI, Cuccurullo F, Porreca E (2007). Modulatory effects of heparin on cellular accumulation and cytotoxicity of doxorubicin in MRP1-overexpressing HL60/doxo cells. Anticancer Res 27, 351-355.
    • (2007) Anticancer Res , vol.27 , pp. 351-355
    • Angelini, A.1    Ciofani, G.2    Baccante, G.3    Di Febbo, C.4    Di Carmine5    Cuccurullo, F.6    Porreca, E.7
  • 5
    • 0034652812 scopus 로고    scopus 로고
    • Engagement of the alpha2beta1 integrin inhibits Fas ligand expression and activation-induced cell death in T cells in a focal adhesion kinase-dependent manner
    • Aoudjit F, Vuori K (2000). Engagement of the alpha2beta1 integrin inhibits Fas ligand expression and activation-induced cell death in T cells in a focal adhesion kinase-dependent manner. Blood 95, 2044-2051.
    • (2000) Blood , vol.95 , pp. 2044-2051
    • Aoudjit, F.1    Vuori, K.2
  • 6
    • 77949904065 scopus 로고    scopus 로고
    • Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin
    • Beedholm-Ebsen R, van de Wetering K, Hardlei T, Nexo E, Borst P, Moestrup SK (2010). Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin. Blood 115, 1632-1639.
    • (2010) Blood , vol.115 , pp. 1632-1639
    • Beedholm-Ebsen, R.1    Van De Wetering, K.2    Hardlei, T.3    Nexo, E.4    Borst, P.5    Moestrup, S.K.6
  • 7
    • 0036829109 scopus 로고    scopus 로고
    • Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6)
    • Belinsky MG, Chen ZS, Shchaveleva I, Zeng H, Kruh GD (2002). Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6). Cancer Res 62, 6172-6177.
    • (2002) Cancer Res , vol.62 , pp. 6172-6177
    • Belinsky, M.G.1    Chen, Z.S.2    Shchaveleva, I.3    Zeng, H.4    Kruh, G.D.5
  • 8
    • 34249338061 scopus 로고    scopus 로고
    • Collagen-mediated survival signaling is modulated by CD45 in Jurkat T cells
    • Bijian K, Zhang L, Shen SH (2007). Collagen-mediated survival signaling is modulated by CD45 in Jurkat T cells. Mol Immunol 44, 3682-3690.
    • (2007) Mol Immunol , vol.44 , pp. 3682-3690
    • Bijian, K.1    Zhang, L.2    Shen, S.H.3
  • 9
    • 33644974376 scopus 로고    scopus 로고
    • Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1
    • Bonhoure E, Pchejetski D, Aouali N, Morjani H, Levade T, Kohama T, Cuvillier O (2006). Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1. Leukemia 20, 95-102.
    • (2006) Leukemia , vol.20 , pp. 95-102
    • Bonhoure, E.1    Pchejetski, D.2    Aouali, N.3    Morjani, H.4    Levade, T.5    Kohama, T.6    Cuvillier, O.7
  • 10
    • 69249094554 scopus 로고    scopus 로고
    • Small-molecule multidrug resistance-associated protein 1 inhibitor Reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma
    • Burkhart CA et al. (2009). Small-molecule multidrug resistance-associated protein 1 inhibitor Reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma. Cancer Res 69, 6573-6580.
    • (2009) Cancer Res , vol.69 , pp. 6573-6580
    • Burkhart, C.A.1
  • 11
    • 0025913787 scopus 로고
    • T cell receptor-dependent, antigen-specific stimulation of a murine T cell clone induces a transient, VLA protein-mediated binding to extracellular matrix
    • Chan BM, Wong JG, Rao A, Hemler ME (1991). T cell receptor-dependent, antigen-specific stimulation of a murine T cell clone induces a transient, VLA protein-mediated binding to extracellular matrix. J Immunol 147, 398-404.
    • (1991) J Immunol , vol.147 , pp. 398-404
    • Chan, B.M.1    Wong, J.G.2    Rao, A.3    Hemler, M.E.4
  • 12
    • 80052449326 scopus 로고    scopus 로고
    • Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases
    • Chen ZS, Tiwari AK (2011). Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases. FEBS J 278, 3226-3245.
    • (2011) FEBS J , vol.278 , pp. 3226-3245
    • Chen, Z.S.1    Tiwari, A.K.2
  • 13
    • 33644538220 scopus 로고    scopus 로고
    • Collagen type I-mediated activation of ERK/MAP kinase is dependent on Ras, Raf-1 and protein phosphatase 2A in Jurkat T cells
    • Chetoui N, Gendron S, Chamoux E, Aoudjit F (2006). Collagen type I-mediated activation of ERK/MAP kinase is dependent on Ras, Raf-1 and protein phosphatase 2A in Jurkat T cells. Mol Immunol 43, 1687-1693.
    • (2006) Mol Immunol , vol.43 , pp. 1687-1693
    • Chetoui, N.1    Gendron, S.2    Chamoux, E.3    Aoudjit, F.4
  • 14
    • 84855501388 scopus 로고    scopus 로고
    • Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells
    • Cho S, Lu M, He X, Ee PL, Bhat U, Schneider E, Miele L, Beck WT (2011). Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells. Proc Natl Acad Sci USA 108, 20778-20783.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 20778-20783
    • Cho, S.1    Lu, M.2    He, X.3    Ee, P.L.4    Bhat, U.5    Schneider, E.6    Miele, L.7    Beck, W.T.8
  • 16
    • 0036121001 scopus 로고    scopus 로고
    • Multidrug resistance mechanisms in chronic lymphocytic leukaemia
    • Consoli U et al. (2002). Multidrug resistance mechanisms in chronic lymphocytic leukaemia. Br J Haematol 116, 774-780.
    • (2002) Br J Haematol , vol.116 , pp. 774-780
    • Consoli, U.1
  • 17
    • 0036234428 scopus 로고    scopus 로고
    • Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis
    • Corpechot C, Barbu V, Wendum D, Kinnman N, Rey C, Poupon R, Housset C, Rosmorduc O (2002). Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. Hepatology 35, 1010-1021.
    • (2002) Hepatology , vol.35 , pp. 1010-1021
    • Corpechot, C.1    Barbu, V.2    Wendum, D.3    Kinnman, N.4    Rey, C.5    Poupon, R.6    Housset, C.7    Rosmorduc, O.8
  • 18
    • 33745835398 scopus 로고    scopus 로고
    • Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
    • Deeley RG, Westlake C, Cole SP (2006). Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol Rev 86, 849-899.
    • (2006) Physiol Rev , vol.86 , pp. 849-899
    • Deeley, R.G.1    Westlake, C.2    Cole, S.P.3
  • 19
    • 79957789588 scopus 로고    scopus 로고
    • Cytohesin-1 regulates fMLF-mediated activation and functions of the beta2 integrin Mac-1 in human neutrophils
    • El Azreq MA, Garceau V, Bourgoin SG (2011). Cytohesin-1 regulates fMLF-mediated activation and functions of the beta2 integrin Mac-1 in human neutrophils. J Leukoc Biol 89, 823-836.
    • (2011) J Leukoc Biol , vol.89 , pp. 823-836
    • El Azreq, M.A.1    Garceau, V.2    Bourgoin, S.G.3
  • 20
    • 79954524112 scopus 로고    scopus 로고
    • Mechanism of cell adaptation: When and how do cancer cells develop chemoresistance?
    • Fodale V, Pierobon M, Liotta L, Petricoin E (2011). Mechanism of cell adaptation: when and how do cancer cells develop chemoresistance? Cancer J 17, 89-95.
    • (2011) Cancer J , vol.17 , pp. 89-95
    • Fodale, V.1    Pierobon, M.2    Liotta, L.3    Petricoin, E.4
  • 21
    • 33749540617 scopus 로고    scopus 로고
    • SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: Glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis
    • Franco R, Cidlowski JA (2006). SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis. J Biol Chem 281, 29542-29557.
    • (2006) J Biol Chem , vol.281 , pp. 29542-29557
    • Franco, R.1    Cidlowski, J.A.2
  • 22
    • 1542467646 scopus 로고    scopus 로고
    • Integrin alpha2beta1 inhibits Fas-mediated apoptosis in T lymphocytes by protein phosphatase 2A-dependent activation of the MAPK/ERK pathway
    • Gendron S, Couture J, Aoudjit F (2003). Integrin alpha2beta1 inhibits Fas-mediated apoptosis in T lymphocytes by protein phosphatase 2A-dependent activation of the MAPK/ERK pathway. J Biol Chem 278, 48633-48643.
    • (2003) J Biol Chem , vol.278 , pp. 48633-48643
    • Gendron, S.1    Couture, J.2    Aoudjit, F.3
  • 23
    • 29744432226 scopus 로고    scopus 로고
    • Collagen type I signaling reduces the expression and the function of human receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes
    • Gendron S, Couture J, Aoudjit F (2005). Collagen type I signaling reduces the expression and the function of human receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes. Eur J Immunol 35, 3673-3682.
    • (2005) Eur J Immunol , vol.35 , pp. 3673-3682
    • Gendron, S.1    Couture, J.2    Aoudjit, F.3
  • 24
    • 66549095477 scopus 로고    scopus 로고
    • Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling
    • Goh F et al. (2009). Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling. Immunology 127, 326-337.
    • (2009) Immunology , vol.127 , pp. 326-337
    • Goh, F.1
  • 26
    • 0032905375 scopus 로고    scopus 로고
    • Evidence for different ABC-transporters in Caco-2 cells modulating drug uptake
    • Gutmann H, Fricker G, Torok M, Michael S, Beglinger C, Drewe J (1999). Evidence for different ABC-transporters in Caco-2 cells modulating drug uptake. Pharm Res 16, 402-407.
    • (1999) Pharm Res , vol.16 , pp. 402-407
    • Gutmann, H.1    Fricker, G.2    Torok, M.3    Michael, S.4    Beglinger, C.5    Drewe, J.6
  • 27
    • 23044472581 scopus 로고    scopus 로고
    • Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract
    • Gutmann H, Hruz P, Zimmermann C, Beglinger C, Drewe J (2005). Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract. Biochem Pharmacol 70, 695-699.
    • (2005) Biochem Pharmacol , vol.70 , pp. 695-699
    • Gutmann, H.1    Hruz, P.2    Zimmermann, C.3    Beglinger, C.4    Drewe, J.5
  • 28
    • 34347230130 scopus 로고    scopus 로고
    • Glutathione export during apoptosis requires functional multidrug resistance-associated proteins
    • Hammond CL, Marchan R, Krance SM, Ballatori N (2007). Glutathione export during apoptosis requires functional multidrug resistance-associated proteins. J Biol Chem 282, 14337-14347.
    • (2007) J Biol Chem , vol.282 , pp. 14337-14347
    • Hammond, C.L.1    Marchan, R.2    Krance, S.M.3    Ballatori, N.4
  • 29
    • 71049195408 scopus 로고    scopus 로고
    • Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses
    • Han L, Wierenga AT, Rozenveld-Geugien M, van de Lande K, Vellenga E, Schuringa JJ (2009). Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses. PLoS One 4, e7989.
    • (2009) PLoS One , vol.4
    • Han, L.1    Wierenga, A.T.2    Rozenveld-Geugien, M.3    Van De Lande, K.4    Vellenga, E.5    Schuringa, J.J.6
  • 30
    • 65649146880 scopus 로고    scopus 로고
    • Integrin signalling at a glance
    • Harburger DS, Calderwood DA (2009). Integrin signalling at a glance. J Cell Sci 122, 159-163.
    • (2009) J Cell Sci , vol.122 , pp. 159-163
    • Harburger, D.S.1    Calderwood, D.A.2
  • 31
    • 33845329178 scopus 로고    scopus 로고
    • Signalling via integrins: Implications for cell survival and anticancer strategies
    • Hehlgans S, Haase M, Cordes N (2007). Signalling via integrins: implications for cell survival and anticancer strategies. Biochim Biophys Acta 1775, 163-180.
    • (2007) Biochim Biophys Acta , vol.1775 , pp. 163-180
    • Hehlgans, S.1    Haase, M.2    Cordes, N.3
  • 32
    • 78751481792 scopus 로고    scopus 로고
    • Multidrug resistance-related protein 1 (MRP1) function and localization depend on cortical actin
    • Hummel I, Klappe K, Ercan C, Kok JW (2011). Multidrug resistance-related protein 1 (MRP1) function and localization depend on cortical actin. Mol Pharmacol 79, 229-240.
    • (2011) Mol Pharmacol , vol.79 , pp. 229-240
    • Hummel, I.1    Klappe, K.2    Ercan, C.3    Kok, J.W.4
  • 34
    • 0032817056 scopus 로고    scopus 로고
    • Adult T-cell leukemia cells over-express the multidrug-resistance-protein (MRP) and lung-resistance-protein (LRP) genes
    • Ikeda K et al. (1999). Adult T-cell leukemia cells over-express the multidrug-resistance-protein (MRP) and lung-resistance-protein (LRP) genes. Int J Cancer 82, 599-604.
    • (1999) Int J Cancer , vol.82 , pp. 599-604
    • Ikeda, K.1
  • 35
    • 11144334090 scopus 로고    scopus 로고
    • The role of chemokines and extracellular matrix components in the migration of T lymphocytes into three-dimensional substrata
    • Ivanoff J, Talme T, Sundqvist KG (2005). The role of chemokines and extracellular matrix components in the migration of T lymphocytes into three-dimensional substrata. Immunology 114, 53-62.
    • (2005) Immunology , vol.114 , pp. 53-62
    • Ivanoff, J.1    Talme, T.2    Sundqvist, K.G.3
  • 36
    • 0034806474 scopus 로고    scopus 로고
    • Identification of DNA-protein interactions in the 5′ flanking and 5′ untranslated regions of the human multidrug resistance protein (MRP1) gene: Evaluation of a putative antioxidant response element/AP-1 binding site
    • Kurz EU, Cole SP, Deeley RG (2001). Identification of DNA-protein interactions in the 5′ flanking and 5′ untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site. Biochem Biophys Res Commun 285, 981-990.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 981-990
    • Kurz, E.U.1    Cole, S.P.2    Deeley, R.G.3
  • 37
    • 79960675115 scopus 로고    scopus 로고
    • Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters
    • Lebedeva IV, Pande P, Patton WF (2011). Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters. PLoS One 6, e22429.
    • (2011) PLoS One , vol.6
    • Lebedeva, I.V.1    Pande, P.2    Patton, W.F.3
  • 38
    • 0035986576 scopus 로고    scopus 로고
    • Differential regulation of P-glycoprotein genes in primary rat hepatocytes by collagen sandwich and drugs
    • Lee CH (2002). Differential regulation of P-glycoprotein genes in primary rat hepatocytes by collagen sandwich and drugs. J Cell Biochem 86, 12-20.
    • (2002) J Cell Biochem , vol.86 , pp. 12-20
    • Lee, C.H.1
  • 39
    • 3442879850 scopus 로고    scopus 로고
    • Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways
    • Lee JW, Juliano R (2004). Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways. Mol Cells 17, 188-202.
    • (2004) Mol Cells , vol.17 , pp. 188-202
    • Lee, J.W.1    Juliano, R.2
  • 40
    • 33745837774 scopus 로고    scopus 로고
    • Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
    • Loeffler M, Kruger JA, Niethammer AG, Reisfeld RA (2006). Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J Clin Invest 116, 1955-1962.
    • (2006) J Clin Invest , vol.116 , pp. 1955-1962
    • Loeffler, M.1    Kruger, J.A.2    Niethammer, A.G.3    Reisfeld, R.A.4
  • 41
    • 39049188220 scopus 로고    scopus 로고
    • Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells
    • Lotz C, Kelleher DK, Gassner B, Gekle M, Vaupel P, Thews O (2007). Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells. Oncol Rep 17, 239-244.
    • (2007) Oncol Rep , vol.17 , pp. 239-244
    • Lotz, C.1    Kelleher, D.K.2    Gassner, B.3    Gekle, M.4    Vaupel, P.5    Thews, O.6
  • 42
    • 23844481408 scopus 로고    scopus 로고
    • Mechanisms of drug resistance in cancer chemotherapy
    • Luqmani YA (2005). Mechanisms of drug resistance in cancer chemotherapy. Med Princ Pract 14(Suppl 1), 35-48.
    • (2005) Med Princ Pract , vol.14 , Issue.SUPPL. 1 , pp. 35-48
    • Luqmani, Y.A.1
  • 43
    • 0031438213 scopus 로고    scopus 로고
    • The MDR1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes
    • Martel J, Payet MD, Dupuis G (1997). The MDR1 (P-glycoprotein) and MRP (P-190) transporters do not play a major role in the intrinsic multiple drug resistance of Jurkat T lymphocytes. Leuk Res 21, 1077-1086.
    • (1997) Leuk Res , vol.21 , pp. 1077-1086
    • Martel, J.1    Payet, M.D.2    Dupuis, G.3
  • 44
    • 69249087671 scopus 로고    scopus 로고
    • Environment-mediated drug resistance: A major contributor to minimal residual disease
    • Meads MB, Gatenby RA, Dalton WS (2009). Environment-mediated drug resistance: a major contributor to minimal residual disease. Nat Rev Cancer 9, 665-674.
    • (2009) Nat Rev Cancer , vol.9 , pp. 665-674
    • Meads, M.B.1    Gatenby, R.A.2    Dalton, W.S.3
  • 45
    • 52049103847 scopus 로고    scopus 로고
    • The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
    • Meads MB, Hazlehurst LA, Dalton WS (2008). The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance. Clin Cancer Res 14, 2519-2526.
    • (2008) Clin Cancer Res , vol.14 , pp. 2519-2526
    • Meads, M.B.1    Hazlehurst, L.A.2    Dalton, W.S.3
  • 48
    • 0034193258 scopus 로고    scopus 로고
    • Role of extra-cellular matrix assembly in interstitial transport in solid tumors
    • Netti PA, Berk DA, Swartz MA, Grodzinsky AJ, Jain RK (2000). Role of extra-cellular matrix assembly in interstitial transport in solid tumors. Cancer Res 60, 2497-2503.
    • (2000) Cancer Res , vol.60 , pp. 2497-2503
    • Netti, P.A.1    Berk, D.A.2    Swartz, M.A.3    Grodzinsky, A.J.4    Jain, R.K.5
  • 49
    • 0025115739 scopus 로고
    • Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction
    • Noonan KE et al. (1990). Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc Natl Acad Sci USA 87, 7160-7164.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7160-7164
    • Noonan, K.E.1
  • 51
    • 6344242987 scopus 로고    scopus 로고
    • Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells
    • Prime-Chapman HM, Fearn RA, Cooper AE, Moore V, Hirst BH (2004). Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells. J Pharmacol Exp Ther 311, 476-484.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 476-484
    • Prime-Chapman, H.M.1    Fearn, R.A.2    Cooper, A.E.3    Moore, V.4    Hirst, B.H.5
  • 52
    • 33646270828 scopus 로고    scopus 로고
    • Cytochrome P450 interactions in human cancers: New aspects considering CYP1B1
    • Roos PH, Bolt HM (2005). Cytochrome P450 interactions in human cancers: new aspects considering CYP1B1. Expert Opin Drug Metab Toxicol 1, 187-202.
    • (2005) Expert Opin Drug Metab Toxicol , vol.1 , pp. 187-202
    • Roos, P.H.1    Bolt, H.M.2
  • 54
    • 0037079708 scopus 로고    scopus 로고
    • The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
    • Scharenberg CW, Harkey MA, Torok-Storb B (2002). The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 99, 507-512.
    • (2002) Blood , vol.99 , pp. 507-512
    • Scharenberg, C.W.1    Harkey, M.A.2    Torok-Storb, B.3
  • 55
    • 84856271899 scopus 로고    scopus 로고
    • The P-glycoprotein multidrug transporter
    • Sharom FJ (2011). The P-glycoprotein multidrug transporter. Essays Biochem 50, 161-178.
    • (2011) Essays Biochem , vol.50 , pp. 161-178
    • Sharom, F.J.1
  • 57
    • 61949262034 scopus 로고    scopus 로고
    • Integrins and cell-fate determination
    • Streuli CH (2009). Integrins and cell-fate determination. J Cell Sci 122, 171-177.
    • (2009) J Cell Sci , vol.122 , pp. 171-177
    • Streuli, C.H.1
  • 58
    • 84934441145 scopus 로고    scopus 로고
    • Hypoxia-induced extracellular acidosis increases p-glycoprotein activity and chemoresistance in tumors in vivo via p38 signaling pathway
    • Thews O, Nowak M, Sauvant C, Gekle M (2011). Hypoxia-induced extracellular acidosis increases p-glycoprotein activity and chemoresistance in tumors in vivo via p38 signaling pathway. Adv Exp Med Biol 701, 115-122.
    • (2011) Adv Exp Med Biol , vol.701 , pp. 115-122
    • Thews, O.1    Nowak, M.2    Sauvant, C.3    Gekle, M.4
  • 59
    • 84865723556 scopus 로고    scopus 로고
    • Impact of the metabolic tumor microenvironment on activity and expression of the multidrug resistance-related protein 1 (MRP1)
    • Thews O, Sauvant C, Gekle M (2009). Impact of the metabolic tumor microenvironment on activity and expression of the multidrug resistance-related protein 1 (MRP1). Acta Physiol 195(Suppl 669), O123.
    • (2009) Acta Physiol , vol.195 , Issue.SUPPL. 669
    • Thews, O.1    Sauvant, C.2    Gekle, M.3
  • 60
    • 33646490327 scopus 로고    scopus 로고
    • Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes
    • Turncliff RZ, Tian X, Brouwer KL (2006). Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes. Biochem Pharmacol 71, 1520-1529.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1520-1529
    • Turncliff, R.Z.1    Tian, X.2    Brouwer, K.L.3
  • 61
    • 27744564167 scopus 로고    scopus 로고
    • Two functional active conformations of the integrin α2β1, depending on activation condition and cell type
    • Van de Walle GR, Vanhoorelbeke K, Majer Z, Illyes E, Baert J, Pareyn I, Deckmyn H (2005). Two functional active conformations of the integrin α2β1, depending on activation condition and cell type. J Biol Chem 280, 36873-36882.
    • (2005) J Biol Chem , vol.280 , pp. 36873-36882
    • Van De Walle, G.R.1    Vanhoorelbeke, K.2    Majer, Z.3    Illyes, E.4    Baert, J.5    Pareyn, I.6    Deckmyn, H.7
  • 63
    • 33644865443 scopus 로고    scopus 로고
    • ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells
    • Xu C, Shen G, Yuan X, Kim JH, Gopalkrishnan A, Keum YS, Nair S, Kong AN (2006). ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells. Carcinogenesis 27, 437-445.
    • (2006) Carcinogenesis , vol.27 , pp. 437-445
    • Xu, C.1    Shen, G.2    Yuan, X.3    Kim, J.H.4    Gopalkrishnan, A.5    Keum, Y.S.6    Nair, S.7    Kong, A.N.8


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