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Volumn 20, Issue 3, 2018, Pages

Update on Antiphospholipid Syndrome: Ten Topics in 2017

Author keywords

Anti phospholipid antibodies; APS treatment; Asymptomatic carrier; Neuropsychological development; Obstetric APS; Thrombosis pathogenesis

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; CORTICOSTEROID; CYCLOPHOSPHAMIDE; ECULIZUMAB; FLUINDOSTATIN; HYDROXYCHLOROQUINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN; LA ANTIBODY; LOW MOLECULAR WEIGHT HEPARIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; ORAL CONTRACEPTIVE AGENT; PHOSPHOLIPID ANTIBODY; PREDNISOLONE; RAPAMYCIN; RITUXIMAB; TOLL LIKE RECEPTOR; VITAMIN D; BIOLOGICAL MARKER;

EID: 85044267719     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-018-0718-4     Document Type: Review
Times cited : (19)

References (168)
  • 1
    • 84862909113 scopus 로고    scopus 로고
    • A novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies
    • COI: 1:CAS:528:DC%2BC38Xhs1KjurY%3D
    • Allen KL, Fonseca FV, Betapudi V, Willard B, Zhang J, McCrae KR. A novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies. Blood. 2012;119:884–93.
    • (2012) Blood , vol.119 , pp. 884-893
    • Allen, K.L.1    Fonseca, F.V.2    Betapudi, V.3    Willard, B.4    Zhang, J.5    McCrae, K.R.6
  • 2
    • 84942981664 scopus 로고    scopus 로고
    • A novel pathway of cellular activation mediated by antiphospholipid antibody-induced extracellular vesicles
    • COI: 1:CAS:528:DC%2BC2MXhs1eku77P
    • Wu M, Barnard J, Kundu S, McCrae KR. A novel pathway of cellular activation mediated by antiphospholipid antibody-induced extracellular vesicles. J Thromb Haemost. 2015;13:1928–40.
    • (2015) J Thromb Haemost , vol.13 , pp. 1928-1940
    • Wu, M.1    Barnard, J.2    Kundu, S.3    McCrae, K.R.4
  • 3
    • 84908674518 scopus 로고    scopus 로고
    • Toll-like receptor 4 and β2 glycoprotein I interaction on endothelial cells
    • COI: 1:STN:280:DC%2BC2M7itFOrsw%3D%3D, Oct
    • Borghi MO, Raschi E, Grossi C, Chighizola CB, Meroni PL. Toll-like receptor 4 and β2 glycoprotein I interaction on endothelial cells. Lupus. 2014 Oct;23(12):1302–4.
    • (2014) Lupus , vol.23 , Issue.12 , pp. 1302-1304
    • Borghi, M.O.1    Raschi, E.2    Grossi, C.3    Chighizola, C.B.4    Meroni, P.L.5
  • 4
    • 84922625916 scopus 로고    scopus 로고
    • AKT/mTORC pathway in antiphospholipid-related vasculopathy: a new player in the game
    • COI: 1:CAS:528:DC%2BC2MXjt1GgsrY%3D
    • Canaud G, Legendre C, Terzi F. AKT/mTORC pathway in antiphospholipid-related vasculopathy: a new player in the game. Lupus. 2015;24:227–30.
    • (2015) Lupus , vol.24 , pp. 227-230
    • Canaud, G.1    Legendre, C.2    Terzi, F.3
  • 5
    • 0033586656 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
    • COI: 1:CAS:528:DyaK1MXivFSrsbo%3D
    • Pierangeli SS, Colden-Stanfield M, Liu X, Barker JH, Anderson GL, Harris EN. Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo. Circulation. 1999;99:1997–2002.
    • (1999) Circulation , vol.99 , pp. 1997-2002
    • Pierangeli, S.S.1    Colden-Stanfield, M.2    Liu, X.3    Barker, J.H.4    Anderson, G.L.5    Harris, E.N.6
  • 7
    • 84991712940 scopus 로고    scopus 로고
    • Monocyte type I interferon signature in antiphospholipid syndrome is related to proinflammatory monocyte subsets, hydroxychloroquine and statin use
    • The paper analyzes type I interferon signatures in patients with APS, associated with a deficit of reparative endothelial cell progenitors and endothelial damage
    • • van den Hoogen LL, Fritsch-Stork RD, Versnel MA, Derksen RH, van Roon JA, Radstake TR. Monocyte type I interferon signature in antiphospholipid syndrome is related to proinflammatory monocyte subsets, hydroxychloroquine and statin use. Ann Rheum Dis. 2016;75:e81. The paper analyzes type I interferon signatures in patients with APS, associated with a deficit of reparative endothelial cell progenitors and endothelial damage.
    • (2016) Ann Rheum Dis , vol.75
    • van den Hoogen, L.L.1    Fritsch-Stork, R.D.2    Versnel, M.A.3    Derksen, R.H.4    van Roon, J.A.5    Radstake, T.R.6
  • 8
    • 58449098695 scopus 로고    scopus 로고
    • Platelets and the antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BD1cXhtlKru7%2FO
    • Urbanus RT, Derksen RH, de Groot PG. Platelets and the antiphospholipid syndrome. Lupus. 2008;17:888–94.
    • (2008) Lupus , vol.17 , pp. 888-894
    • Urbanus, R.T.1    Derksen, R.H.2    de Groot, P.G.3
  • 9
    • 85014099037 scopus 로고    scopus 로고
    • Meng H, Yalavarthi S, Kanthi Y, Mazza LF, Elfine MA, Luke CE, et al, 69:655–67. This paper describes the role of activated neutrophils in APs in endothelial dysfunction and pathogenesis of thrombosis, by releasing neutrophil extracellular traps
    • • Meng H, Yalavarthi S, Kanthi Y, Mazza LF, Elfine MA, Luke CE, et al. Role of neutrophil extracellular traps in antiphospholipid antibody-mediated venous thrombosis. 2017;Arthritis Rheumatol, 69:655–67. This paper describes the role of activated neutrophils in APs in endothelial dysfunction and pathogenesis of thrombosis, by releasing neutrophil extracellular traps.
    • Role of neutrophil extracellular traps in antiphospholipid antibody-mediated venous thrombosis. 2017;Arthritis Rheumatol
  • 10
    • 84946099830 scopus 로고    scopus 로고
    • Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2MXhslOksbfN
    • Yalavarthi S, Gould TJ, Rao AN, Mazza LF, Morris LE, Nunez-Alvarez C, et al. Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the antiphospholipid syndrome. Arthritis Rheumatol. 2015;67:2990–3003.
    • (2015) Arthritis Rheumatol , vol.67 , pp. 2990-3003
    • Yalavarthi, S.1    Gould, T.J.2    Rao, A.N.3    Mazza, L.F.4    Morris, L.E.5    Nunez-Alvarez, C.6
  • 11
    • 85044328539 scopus 로고    scopus 로고
    • Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target
    • Knight JS, Meng H, Coit P, Yalavarthi S, Sule G, Gandhi AA, et al. Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target. JCI Insight. 2017;21:2(18).
    • (2017) JCI Insight , vol.21 , pp. 2(18)
    • Knight, J.S.1    Meng, H.2    Coit, P.3    Yalavarthi, S.4    Sule, G.5    Gandhi, A.A.6
  • 12
    • 67650651969 scopus 로고    scopus 로고
    • Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway
    • COI: 1:CAS:528:DC%2BD1MXhtVeisLfK
    • Mulla MJ, Brosens JJ, Chamley LW, Giles I, Pericleous C, Rahman A, et al. Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway. Am J Reprod Immunol. 2009;62:96–111.
    • (2009) Am J Reprod Immunol , vol.62 , pp. 96-111
    • Mulla, M.J.1    Brosens, J.J.2    Chamley, L.W.3    Giles, I.4    Pericleous, C.5    Rahman, A.6
  • 13
    • 84963800435 scopus 로고    scopus 로고
    • ApoE receptor 2 mediation of trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice
    • COI: 1:CAS:528:DC%2BC28XjsFejsLw%3D
    • Ulrich V, Gelber SE, Vukelic M, Sacharidou A, Herz J, Urbanus RT, et al. ApoE receptor 2 mediation of trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice. Arthritis Rheum. 2016;68:730–9.
    • (2016) Arthritis Rheum , vol.68 , pp. 730-739
    • Ulrich, V.1    Gelber, S.E.2    Vukelic, M.3    Sacharidou, A.4    Herz, J.5    Urbanus, R.T.6
  • 14
    • 84902107289 scopus 로고    scopus 로고
    • Hydroxychloroquine restores trophoblast fusion affected by antiphospholipid antibodies
    • COI: 1:CAS:528:DC%2BC2cXpslKhur4%3D
    • Marchetti T, Ruffatti A, Wuillemin C, de Moerloose P, Cohen M. Hydroxychloroquine restores trophoblast fusion affected by antiphospholipid antibodies. J Thromb Haemost. 2014;12:910–20.
    • (2014) J Thromb Haemost , vol.12 , pp. 910-920
    • Marchetti, T.1    Ruffatti, A.2    Wuillemin, C.3    de Moerloose, P.4    Cohen, M.5
  • 15
    • 85007218050 scopus 로고    scopus 로고
    • Placental histology and neutrophil extracellular traps in lupus and pre-eclampsia pregnancies
    • Marder W, Knight JS, Kaplan MJ, Somers EC, Zhang X, O'Dell AA, et al. Placental histology and neutrophil extracellular traps in lupus and pre-eclampsia pregnancies. Lupus Sci Med. 2016;3:e000134.
    • (2016) Lupus Sci Med , vol.3
    • Marder, W.1    Knight, J.S.2    Kaplan, M.J.3    Somers, E.C.4    Zhang, X.5    O'Dell, A.A.6
  • 16
    • 0346969977 scopus 로고    scopus 로고
    • Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BD3sXpslens74%3D
    • Girardi G, Berman J, Redecha P, Spruce L, Thurman JM, Kraus D, et al. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest. 2003;112:1644–54.
    • (2003) J Clin Invest , vol.112 , pp. 1644-1654
    • Girardi, G.1    Berman, J.2    Redecha, P.3    Spruce, L.4    Thurman, J.M.5    Kraus, D.6
  • 17
    • 85024858233 scopus 로고    scopus 로고
    • Emerging treatment models in rheumatology: antiphospholipid syndrome and pregnancy: pathogenesis to translation
    • Abrahams VM, Chamley LW, Salmon JE. Emerging treatment models in rheumatology: antiphospholipid syndrome and pregnancy: pathogenesis to translation. Arthritis Rheum. 2017;69:1710–21.
    • (2017) Arthritis Rheum , vol.69 , pp. 1710-1721
    • Abrahams, V.M.1    Chamley, L.W.2    Salmon, J.E.3
  • 18
    • 84922593999 scopus 로고    scopus 로고
    • 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends
    • Bertolaccini ML, Amengual O, Andreoli L, Atsumi T, Chighizola CB, Forastiero R, et al. 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends. Autoimmun Rev. 2014;13:917–30.
    • (2014) Autoimmun Rev , vol.13 , pp. 917-930
    • Bertolaccini, M.L.1    Amengual, O.2    Andreoli, L.3    Atsumi, T.4    Chighizola, C.B.5    Forastiero, R.6
  • 19
    • 84896702818 scopus 로고    scopus 로고
    • New tests to detect antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies
    • Chighizola CB, Gerosa M, Meroni PL. New tests to detect antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies. Curr Rheumatol Rep. 2014;16:402.
    • (2014) Curr Rheumatol Rep , vol.16 , pp. 402
    • Chighizola, C.B.1    Gerosa, M.2    Meroni, P.L.3
  • 20
    • 84928773743 scopus 로고    scopus 로고
    • Antiphospholipid syndrome: antibodies to domain 1 of beta2-glycoprotein 1 correctly classify patients at risk
    • COI: 1:CAS:528:DC%2BC2MXotVelurk%3D
    • Pengo V, Ruffatti A, Tonello M, Cuffaro S, Banzato A, Bison E, et al. Antiphospholipid syndrome: antibodies to domain 1 of beta2-glycoprotein 1 correctly classify patients at risk. J Thromb Haemost. 2015;13:782–7.
    • (2015) J Thromb Haemost , vol.13 , pp. 782-787
    • Pengo, V.1    Ruffatti, A.2    Tonello, M.3    Cuffaro, S.4    Banzato, A.5    Bison, E.6
  • 21
    • 84929000742 scopus 로고    scopus 로고
    • Detection of IgG anti-domain I beta2 glycoprotein I antibodies by chemiluminescence immunoassay in primary antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2MXnvVSgsLk%3D
    • Meneghel L, Ruffatti A, Gavasso S, Tonello M, Mattia E, Spiezia L, et al. Detection of IgG anti-domain I beta2 glycoprotein I antibodies by chemiluminescence immunoassay in primary antiphospholipid syndrome. Clin Chim Acta. 2015;446:201–5.
    • (2015) Clin Chim Acta , vol.446 , pp. 201-205
    • Meneghel, L.1    Ruffatti, A.2    Gavasso, S.3    Tonello, M.4    Mattia, E.5    Spiezia, L.6
  • 22
    • 84988483807 scopus 로고    scopus 로고
    • Role of anti-domain 1-beta2 glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome
    • De Craemer AS, Musial J, Devreese KM. Role of anti-domain 1-beta2 glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome. J Thromb Haemost. 2016;14:1779–87.
    • (2016) J Thromb Haemost , vol.14 , pp. 1779-1787
    • De Craemer, A.S.1    Musial, J.2    Devreese, K.M.3
  • 23
    • 84938099968 scopus 로고    scopus 로고
    • Clinical characterization of antiphospholipid syndrome by detection of IgG antibodies against beta-glycoprotein I domain 1 and domain 4/5: ratio of anti-domain 1 to anti-domain 4/5 as a useful new biomarker for antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2MXht1yhsL3I
    • Andreoli L, Chighizola CB, Nalli C, Gerosa M, Borghi MO, Pregnolato F, et al. Clinical characterization of antiphospholipid syndrome by detection of IgG antibodies against beta-glycoprotein I domain 1 and domain 4/5: ratio of anti-domain 1 to anti-domain 4/5 as a useful new biomarker for antiphospholipid syndrome. Arthritis Rheum. 2015;67:2196–204.
    • (2015) Arthritis Rheum , vol.67 , pp. 2196-2204
    • Andreoli, L.1    Chighizola, C.B.2    Nalli, C.3    Gerosa, M.4    Borghi, M.O.5    Pregnolato, F.6
  • 24
    • 84896725362 scopus 로고    scopus 로고
    • Role of antiphospholipid score and anti-beta2-glycoprotein I domain I autoantibodies in the diagnosis of antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2cXmtVagurw%3D
    • Mondejar R, Gonzalez-Rodriguez C, Toyos-Saenz de Miera FJ, Melguizo-Madrid E, Zohoury N, Mahler M, et al. Role of antiphospholipid score and anti-beta2-glycoprotein I domain I autoantibodies in the diagnosis of antiphospholipid syndrome. Clin Chim Acta. 2014;431:174–8.
    • (2014) Clin Chim Acta , vol.431 , pp. 174-178
    • Mondejar, R.1    Gonzalez-Rodriguez, C.2    Toyos-Saenz de Miera, F.J.3    Melguizo-Madrid, E.4    Zohoury, N.5    Mahler, M.6
  • 25
    • 85026999474 scopus 로고    scopus 로고
    • Radin M, Cecchi I, Roccatello D, Meroni PL, Sciascia S. This review estimates the prevalence of anti-beta-2-GPI-domain I in patients with APS (analyzing 11 studies and 1585 patients), in order to determine whether anti--beta-2-GPI-domain I-positive individuals are at greater risk of thrombosis
    • •• Radin M, Cecchi I, Roccatello D, Meroni PL, Sciascia S. Prevalence and thrombotic risk assessment of anti-beta2 glycoprotein I domain I antibodies: a systematic review. Seminars in thrombosis and hemostasis. 2017; https://doi.org/10.1055/s-0037-1603936. This review estimates the prevalence of anti-beta-2-GPI-domain I in patients with APS (analyzing 11 studies and 1585 patients), in order to determine whether anti--beta-2-GPI-domain I-positive individuals are at greater risk of thrombosis.
    • (2017) Prevalence and thrombotic risk assessment of anti-beta2 glycoprotein I domain I antibodies: a systematic review. Seminars in thrombosis and hemostasis
  • 26
    • 84973358481 scopus 로고    scopus 로고
    • Autoantibodies to domain 1 of beta 2 glycoprotein I determined using a novel chemiluminescence immunoassay demonstrate association with thrombosis in patients with antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC28XitFWrt7rO
    • Mahler M, Albesa R, Zohoury N, Bertolaccini ML, Ateka-Barrutia O, Rodriguez-Garcia JL, et al. Autoantibodies to domain 1 of beta 2 glycoprotein I determined using a novel chemiluminescence immunoassay demonstrate association with thrombosis in patients with antiphospholipid syndrome. Lupus. 2016;25:911–6.
    • (2016) Lupus , vol.25 , pp. 911-916
    • Mahler, M.1    Albesa, R.2    Zohoury, N.3    Bertolaccini, M.L.4    Ateka-Barrutia, O.5    Rodriguez-Garcia, J.L.6
  • 27
    • 85016294465 scopus 로고    scopus 로고
    • Clinical significance of anti-domain 1 beta2-glycoprotein I antibodies in antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2sXlt1Ciu7s%3D
    • Iwaniec T, Kaczor MP, Celinska-Lowenhoff M, Polanski S, Musial J. Clinical significance of anti-domain 1 beta2-glycoprotein I antibodies in antiphospholipid syndrome. Thromb Res. 2017;153:90–4.
    • (2017) Thromb Res , vol.153 , pp. 90-94
    • Iwaniec, T.1    Kaczor, M.P.2    Celinska-Lowenhoff, M.3    Polanski, S.4    Musial, J.5
  • 28
    • 84930801033 scopus 로고    scopus 로고
    • The clinical performance of a chemiluminescent immunoassay in detecting anti-cardiolipin and anti-beta2 glycoprotein I antibodies. A comparison with a homemade ELISA method
    • COI: 1:CAS:528:DC%2BC2MXps1SmsrY%3D
    • Meneghel L, Ruffatti A, Gavasso S, Tonello M, Mattia E, Spiezia L, et al. The clinical performance of a chemiluminescent immunoassay in detecting anti-cardiolipin and anti-beta2 glycoprotein I antibodies. A comparison with a homemade ELISA method. Clin Chem Lab Med. 2015;53:1083–9.
    • (2015) Clin Chem Lab Med , vol.53 , pp. 1083-1089
    • Meneghel, L.1    Ruffatti, A.2    Gavasso, S.3    Tonello, M.4    Mattia, E.5    Spiezia, L.6
  • 29
    • 84928335529 scopus 로고    scopus 로고
    • A contribution to detection of anticardiolipin and anti-beta2glycoprotein I antibodies: comparison between a home-made ELISA and a fluorescence enzyme immunoassay
    • COI: 1:CAS:528:DC%2BC2MXmvFalt7k%3D
    • Mattia E, Ruffatti A, Meneghel L, Tonello M, Faggian D, Hoxha A, et al. A contribution to detection of anticardiolipin and anti-beta2glycoprotein I antibodies: comparison between a home-made ELISA and a fluorescence enzyme immunoassay. Clinica Chimica Acta; Int J Clin Chem. 2015;446:93–6.
    • (2015) Clinica Chimica Acta; Int J Clin Chem , vol.446 , pp. 93-96
    • Mattia, E.1    Ruffatti, A.2    Meneghel, L.3    Tonello, M.4    Faggian, D.5    Hoxha, A.6
  • 30
    • 85007196298 scopus 로고    scopus 로고
    • A multicenter study to assess the reproducibility of antiphospholipid antibody results produced by an automated system
    • COI: 1:STN:280:DC%2BC2snivF2qsA%3D%3D
    • Devreese KM, Poncet A, Lindhoff-Last E, Musial J, de Moerloose P, Fontana P. A multicenter study to assess the reproducibility of antiphospholipid antibody results produced by an automated system. J Thromb Haemost. 2017;15:91–5.
    • (2017) J Thromb Haemost , vol.15 , pp. 91-95
    • Devreese, K.M.1    Poncet, A.2    Lindhoff-Last, E.3    Musial, J.4    de Moerloose, P.5    Fontana, P.6
  • 31
    • 84981294324 scopus 로고    scopus 로고
    • Validation of a new panel of automated chemiluminescence assays for anticardiolipin antibodies in the screening for antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2sXhs1GjtrbM
    • Janek D, Slavik L, Ulehlova J, Krcova V, Hlusi A, Prochazkova J. Validation of a new panel of automated chemiluminescence assays for anticardiolipin antibodies in the screening for antiphospholipid syndrome. Clin Lab. 2016;62:1309–15.
    • (2016) Clin Lab , vol.62 , pp. 1309-1315
    • Janek, D.1    Slavik, L.2    Ulehlova, J.3    Krcova, V.4    Hlusi, A.5    Prochazkova, J.6
  • 32
    • 84855294117 scopus 로고    scopus 로고
    • International consensus guidelines on anticardiolipin and anti-beta2-glycoprotein I testing: report from the 13th International Congress on antiphospholipid antibodies
    • Lakos G, Favaloro EJ, Harris EN, Meroni PL, Tincani A, Wong RC, et al. International consensus guidelines on anticardiolipin and anti-beta2-glycoprotein I testing: report from the 13th International Congress on antiphospholipid antibodies. Arthritis Rheum. 2012;64:1–10.
    • (2012) Arthritis Rheum , vol.64 , pp. 1-10
    • Lakos, G.1    Favaloro, E.J.2    Harris, E.N.3    Meroni, P.L.4    Tincani, A.5    Wong, R.C.6
  • 33
    • 0037114142 scopus 로고    scopus 로고
    • Use of single point mutations in domain I of beta 2-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies
    • COI: 1:CAS:528:DC%2BD38XpsFGjtr4%3D
    • Iverson GM, Reddel S, Victoria EJ, Cockerill KA, Wang YX, Marti-Renom MA, et al. Use of single point mutations in domain I of beta 2-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies. J Immunol. 2002;169:7097–103.
    • (2002) J Immunol , vol.169 , pp. 7097-7103
    • Iverson, G.M.1    Reddel, S.2    Victoria, E.J.3    Cockerill, K.A.4    Wang, Y.X.5    Marti-Renom, M.A.6
  • 34
    • 0042832999 scopus 로고    scopus 로고
    • Prevalence and clinical correlations of antibodies against six beta2-glycoprotein-I-related peptides in the antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BD3sXmsFWitro%3D
    • Shoenfeld Y, Krause I, Kvapil F, Sulkes J, Lev S, von Landenberg P, et al. Prevalence and clinical correlations of antibodies against six beta2-glycoprotein-I-related peptides in the antiphospholipid syndrome. J Clin Immunol. 2003;23:377–83.
    • (2003) J Clin Immunol , vol.23 , pp. 377-383
    • Shoenfeld, Y.1    Krause, I.2    Kvapil, F.3    Sulkes, J.4    Lev, S.5    von Landenberg, P.6
  • 35
    • 13544276197 scopus 로고    scopus 로고
    • IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis
    • de Laat B, Derksen RH, Urbanus RT, de Groot PG. IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis. Blood. 2005;105:1540–5.
    • (2005) Blood , vol.105 , pp. 1540-1545
    • de Laat, B.1    Derksen, R.H.2    Urbanus, R.T.3    de Groot, P.G.4
  • 36
    • 33846236309 scopus 로고    scopus 로고
    • Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43
    • COI: 1:CAS:528:DC%2BD2sXhsFais7Y%3D
    • Ioannou Y, Pericleous C, Giles I, Latchman DS, Isenberg DA, Rahman A. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43. Arthritis Rheum. 2007;56:280–90.
    • (2007) Arthritis Rheum , vol.56 , pp. 280-290
    • Ioannou, Y.1    Pericleous, C.2    Giles, I.3    Latchman, D.S.4    Isenberg, D.A.5    Rahman, A.6
  • 37
    • 79958155528 scopus 로고    scopus 로고
    • Chemical synthesis and characterization of wild-type and biotinylated N-terminal domain 1-64 of beta2-glycoprotein I
    • COI: 1:CAS:528:DC%2BC3cXlsFSgt7g%3D
    • Pozzi N, Banzato A, Bettin S, Bison E, Pengo V, De Filippis V. Chemical synthesis and characterization of wild-type and biotinylated N-terminal domain 1-64 of beta2-glycoprotein I. Protein Sci: a Publication Protein Soc. 2010;19:1065–78.
    • (2010) Protein Sci: a Publication Protein Soc , vol.19 , pp. 1065-1078
    • Pozzi, N.1    Banzato, A.2    Bettin, S.3    Bison, E.4    Pengo, V.5    De Filippis, V.6
  • 38
    • 82355182716 scopus 로고    scopus 로고
    • Antibodies to domain I of beta(2)glycoprotein I are in close relation to patients risk categories in antiphospholipid syndrome (APS)
    • COI: 1:CAS:528:DC%2BC3MXhsFeis7fP
    • Banzato A, Pozzi N, Frasson R, De Filippis V, Ruffatti A, Bison E, et al. Antibodies to domain I of beta(2)glycoprotein I are in close relation to patients risk categories in antiphospholipid syndrome (APS). Thromb Res. 2011;128:583–6.
    • (2011) Thromb Res , vol.128 , pp. 583-586
    • Banzato, A.1    Pozzi, N.2    Frasson, R.3    De Filippis, V.4    Ruffatti, A.5    Bison, E.6
  • 39
    • 84870255310 scopus 로고    scopus 로고
    • Autoantibodies to domain 1 of beta 2 glycoprotein 1: a promising candidate biomarker for risk management in antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC38XptVyit7g%3D
    • Mahler M, Norman GL, Meroni PL, Khamashta M. Autoantibodies to domain 1 of beta 2 glycoprotein 1: a promising candidate biomarker for risk management in antiphospholipid syndrome. Autoimmun Rev. 2012;12:313–7.
    • (2012) Autoimmun Rev , vol.12 , pp. 313-317
    • Mahler, M.1    Norman, G.L.2    Meroni, P.L.3    Khamashta, M.4
  • 40
    • 84969528835 scopus 로고    scopus 로고
    • Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers
    • Roggenbuck D, Borghi MO, Somma V, Büttner T, Schierack P, Hanack K, et al. Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers. Arthritis Res Ther. 2016;18:111.
    • (2016) Arthritis Res Ther , vol.18 , pp. 111
    • Roggenbuck, D.1    Borghi, M.O.2    Somma, V.3    Büttner, T.4    Schierack, P.5    Hanack, K.6
  • 42
    • 79953305113 scopus 로고    scopus 로고
    • Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies
    • COI: 1:STN:280:DC%2BC3M7nvVWqtw%3D%3D
    • Ruiz-Irastorza G, Cuadrado MJ, Ruiz-Arruza I, Brey R, Crowther M, Derksen R, et al. Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies. Lupus. 2011;20:206–18.
    • (2011) Lupus , vol.20 , pp. 206-218
    • Ruiz-Irastorza, G.1    Cuadrado, M.J.2    Ruiz-Arruza, I.3    Brey, R.4    Crowther, M.5    Derksen, R.6
  • 43
    • 37349061734 scopus 로고    scopus 로고
    • A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies
    • Ruiz-Irastorza G, Hunt BJ, Khamashta MA. A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies. Arthritis Rheum. 2007;57:1487–95.
    • (2007) Arthritis Rheum , vol.57 , pp. 1487-1495
    • Ruiz-Irastorza, G.1    Hunt, B.J.2    Khamashta, M.A.3
  • 44
    • 54549099356 scopus 로고    scopus 로고
    • Management of the controversial aspects of the antiphospholipid syndrome pregnancies: a guide for clinicians and researchers
    • Erkan D, Patel S, Nuzzo M, Gerosa M, Meroni PL, Tincani A, et al. Management of the controversial aspects of the antiphospholipid syndrome pregnancies: a guide for clinicians and researchers. Rheumatology (Oxford). 2008;47(Suppl 3):iii23–7.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. iii23-iii27
    • Erkan, D.1    Patel, S.2    Nuzzo, M.3    Gerosa, M.4    Meroni, P.L.5    Tincani, A.6
  • 45
    • 0012444692 scopus 로고    scopus 로고
    • Treatment of pregnant patients with antiphospholipid syndrome
    • COI: 1:STN:280:DC%2BD3szlvFCntQ%3D%3D
    • Tincani A, Branch W, Levy RA, Piette JC, Carp H, Rai RS, et al. Treatment of pregnant patients with antiphospholipid syndrome. Lupus. 2003;12:524–9.
    • (2003) Lupus , vol.12 , pp. 524-529
    • Tincani, A.1    Branch, W.2    Levy, R.A.3    Piette, J.C.4    Carp, H.5    Rai, R.S.6
  • 47
    • 84861480764 scopus 로고    scopus 로고
    • Thromboprophylaxis in carriers of antiphospholipid antibodies (APL) without previous thrombosis: “pros” and “cons
    • Ceccarelli F, Chighizola C, Finazzi G, Meroni PL, Valesini G. Thromboprophylaxis in carriers of antiphospholipid antibodies (APL) without previous thrombosis: “pros” and “cons”. Autoimmun Rev. 2012;11:568–71.
    • (2012) Autoimmun Rev , vol.11 , pp. 568-571
    • Ceccarelli, F.1    Chighizola, C.2    Finazzi, G.3    Meroni, P.L.4    Valesini, G.5
  • 49
    • 34547407889 scopus 로고    scopus 로고
    • Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: a randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals
    • COI: 1:CAS:528:DC%2BD2sXovFSgurs%3D
    • Erkan D, Harrison MJ, Levy R, Peterson M, Petri M, Sammaritano L, et al. Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: a randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals. Arthritis Rheum. 2007;56:2382–91.
    • (2007) Arthritis Rheum , vol.56 , pp. 2382-2391
    • Erkan, D.1    Harrison, M.J.2    Levy, R.3    Peterson, M.4    Petri, M.5    Sammaritano, L.6
  • 50
    • 85042129382 scopus 로고    scopus 로고
    • Erkan D, Unlu O, Sciascia S, Belmont HM, Branch DW, Cuadrado MJ, et al. 1:961203317724219. This is a randomized clinical trial focused on the efficacy of hydroxychloroquine in the primary thrombosis prevention of antiphospholipid antibody (aPL)-positive patients with no other systemic autoimmune diseases
    • • Erkan D, Unlu O, Sciascia S, Belmont HM, Branch DW, Cuadrado MJ, et al. Hydroxychloroquine in the primary thrombosis prophylaxis of antiphospholipid antibody positive patients without systemic autoimmune disease. Lupus. 2017, 1:961203317724219. https://doi.org/10.1177/0961203317724219. This is a randomized clinical trial focused on the efficacy of hydroxychloroquine in the primary thrombosis prevention of antiphospholipid antibody (aPL)-positive patients with no other systemic autoimmune diseases.
    • (2017) Hydroxychloroquine in the primary thrombosis prophylaxis of antiphospholipid antibody positive patients without systemic autoimmune disease. Lupus
  • 51
    • 84978085781 scopus 로고    scopus 로고
    • Long-term use of hydroxychloroquine reduces antiphospholipid antibodies levels in patients with primary antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC28XhtFGrurzJ, This study shows a strong reduction in aPL titers and a decrease in the incidence of arterial thrombosis recurrence in PAPS patients treated with HCQ
    • • Nuri E, Taraborelli M, Andreoli L, Tonello M, Gerosa M, Calligaro A. Long-term use of hydroxychloroquine reduces antiphospholipid antibodies levels in patients with primary antiphospholipid syndrome. Immunol Res. 2017;65:17–24. This study shows a strong reduction in aPL titers and a decrease in the incidence of arterial thrombosis recurrence in PAPS patients treated with HCQ.
    • (2017) Immunol Res , vol.65 , pp. 17-24
    • Nuri, E.1    Taraborelli, M.2    Andreoli, L.3    Tonello, M.4    Gerosa, M.5    Calligaro, A.6
  • 52
    • 80052720931 scopus 로고    scopus 로고
    • The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus
    • Kahlenberg JM, Kaplan MJ. The interplay of inflammation and cardiovascular disease in systemic lupus erythematosus. Arthritis Res Ther. 2011;13:203.
    • (2011) Arthritis Res Ther , vol.13 , pp. 203
    • Kahlenberg, J.M.1    Kaplan, M.J.2
  • 53
    • 73449120372 scopus 로고    scopus 로고
    • Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review
    • COI: 1:CAS:528:DC%2BC3cXhtFOlsrk%3D
    • Ruiz-Irastorza G, Ramos-Casals M, Brito-Zeron P, Khamashta MA. Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review. Ann Rheum Dis. 2010;69:20–8.
    • (2010) Ann Rheum Dis , vol.69 , pp. 20-28
    • Ruiz-Irastorza, G.1    Ramos-Casals, M.2    Brito-Zeron, P.3    Khamashta, M.A.4
  • 54
    • 0034631861 scopus 로고    scopus 로고
    • Prophylactic antithrombotic therapy for patients with or without antiphospholipid antibodies: do the benefit outweigh the risk? A decision analysis
    • COI: 1:STN:280:DC%2BD3czkslKmsg%3D%3D
    • Wahl DG, Bounameaux H, de Moerloose P, Sarasin FP. Prophylactic antithrombotic therapy for patients with or without antiphospholipid antibodies: do the benefit outweigh the risk? A decision analysis. Arch Intern Med. 2000;160:2042–8.
    • (2000) Arch Intern Med , vol.160 , pp. 2042-2048
    • Wahl, D.G.1    Bounameaux, H.2    de Moerloose, P.3    Sarasin, F.P.4
  • 55
    • 63649095045 scopus 로고    scopus 로고
    • Reduction in C-reactive proteinand LDL cholesterol and cardiovascularevent rates after initiation of rosuvastatin: a prospective study of the JUPITER trial
    • COI: 1:CAS:528:DC%2BD1MXktV2gsL8%3D
    • Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, et al. Reduction in C-reactive proteinand LDL cholesterol and cardiovascularevent rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet. 2009;373:1175–82.
    • (2009) Lancet , vol.373 , pp. 1175-1182
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3    Genest, J.4    Gotto, A.M.5    Kastelein, J.J.6
  • 57
    • 78650676621 scopus 로고    scopus 로고
    • Vitamin D: an instrumental factor in the antiphospholipid syndrome by inhibition of tissue factor expression
    • COI: 1:CAS:528:DC%2BC3MXhtleit7g%3D
    • Agmon-Levin N, Blank M, Zandman-Goddard G, Orbach H, Meroni PL, Tincani A, et al. Vitamin D: an instrumental factor in the antiphospholipid syndrome by inhibition of tissue factor expression. Ann Rheum Dis. 2011;70:145–50.
    • (2011) Ann Rheum Dis , vol.70 , pp. 145-150
    • Agmon-Levin, N.1    Blank, M.2    Zandman-Goddard, G.3    Orbach, H.4    Meroni, P.L.5    Tincani, A.6
  • 58
    • 84871434258 scopus 로고    scopus 로고
    • Low levels of vitamin D are common in primary antiphospholipid syndrome with thrombotic disease
    • COI: 1:STN:280:DC%2BC3s3jsFemtg%3D%3D
    • Piantoni S, Andreoli L, Allegri F, Meroni PL, Tincani A. Low levels of vitamin D are common in primary antiphospholipid syndrome with thrombotic disease. Reumatismo. 2012;64:307–13.
    • (2012) Reumatismo , vol.64 , pp. 307-313
    • Piantoni, S.1    Andreoli, L.2    Allegri, F.3    Meroni, P.L.4    Tincani, A.5
  • 59
    • 84882990161 scopus 로고    scopus 로고
    • Persistent antiphospholipid antibodies do not contribute to adverse pregnancy outcomes
    • Soh MC, Pasupathy D, Gray G, Nelson-Piercy C. Persistent antiphospholipid antibodies do not contribute to adverse pregnancy outcomes. Rheumatology. 2013;52:1642–7.
    • (2013) Rheumatology , vol.52 , pp. 1642-1647
    • Soh, M.C.1    Pasupathy, D.2    Gray, G.3    Nelson-Piercy, C.4
  • 60
    • 0033512274 scopus 로고    scopus 로고
    • International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: re-port of an international workshop
    • COI: 1:STN:280:DyaK1MzjtVSmsg%3D%3D
    • Wilson WA, Gharavi AE, Koike T, Lockshin MD, Branch DW, Piette J-C, et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: re-port of an international workshop. Arthritis Rheum. 1999;42:1309–11.
    • (1999) Arthritis Rheum , vol.42 , pp. 1309-1311
    • Wilson, W.A.1    Gharavi, A.E.2    Koike, T.3    Lockshin, M.D.4    Branch, D.W.5    Piette, J.-C.6
  • 61
    • 0027159105 scopus 로고
    • Prevention of fetal loss in experimental antiphospholipid syndrome by in vivo administration of recombinant interleukin-3
    • COI: 1:CAS:528:DyaK3sXisFejtro%3D
    • Fishman P, Falach-Vaknine E, Zigelman R, Bakimer R, Sredni B, Djaldetti M, et al. Prevention of fetal loss in experimental antiphospholipid syndrome by in vivo administration of recombinant interleukin-3. J Clin Invest. 1993;91:1834–7.
    • (1993) J Clin Invest , vol.91 , pp. 1834-1837
    • Fishman, P.1    Falach-Vaknine, E.2    Zigelman, R.3    Bakimer, R.4    Sredni, B.5    Djaldetti, M.6
  • 63
    • 84959175335 scopus 로고    scopus 로고
    • Efficacy and safety of rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome: Rationale and design of the Trial on Rivaroxaban in AntiPhospholipid Syndrome (TRAPS) trial
    • COI: 1:CAS:528:DC%2BC28XpsFyks7k%3D, This is a multicenter, randomized, open-label trial evaluating rivaroxaban versus warfarin for the prevention of thromboembolic events, major bleeding and death in triple-positive patients with antiphospholipid syndrome
    • • Pengo V, Banzato A, Bison E, Zoppellaro G, Padayattil Jose S, Denas G. Efficacy and safety of rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome: Rationale and design of the Trial on Rivaroxaban in AntiPhospholipid Syndrome (TRAPS) trial. Lupus. 2016;25:301–6. This is a multicenter, randomized, open-label trial evaluating rivaroxaban versus warfarin for the prevention of thromboembolic events, major bleeding and death in triple-positive patients with antiphospholipid syndrome.
    • (2016) Lupus , vol.25 , pp. 301-306
    • Pengo, V.1    Banzato, A.2    Bison, E.3    Zoppellaro, G.4    Padayattil Jose, S.5    Denas, G.6
  • 64
    • 84871867984 scopus 로고    scopus 로고
    • Hydroxychloroquine use is associated with lower odds of persistently positive antiphospholipid antibodies and/or lupus anticoagulant in systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BC3sXhvV2huro%3D
    • Broder A, Putterman C. Hydroxychloroquine use is associated with lower odds of persistently positive antiphospholipid antibodies and/or lupus anticoagulant in systemic lupus erythematosus. J Rheumatol. 2013;40:30–3.
    • (2013) J Rheumatol , vol.40 , pp. 30-33
    • Broder, A.1    Putterman, C.2
  • 65
    • 0029001312 scopus 로고
    • Abrogation of experimental systemic lupus erythematosus and primary antiphospholipid syndrome with intravenous gamma globulin
    • COI: 1:CAS:528:DyaK2MXmvFChsr4%3D
    • Krause I, Blank M, Kopolovic J, Afek A, Goldberg I, Tomer Y, et al. Abrogation of experimental systemic lupus erythematosus and primary antiphospholipid syndrome with intravenous gamma globulin. J Rheumatol. 1995;22:1068–74.
    • (1995) J Rheumatol , vol.22 , pp. 1068-1074
    • Krause, I.1    Blank, M.2    Kopolovic, J.3    Afek, A.4    Goldberg, I.5    Tomer, Y.6    Shoenfeld, Y.7
  • 66
    • 84892460524 scopus 로고    scopus 로고
    • Long-term treatment of antiphospholipid syndrome with intravenous immunoglobulin in addition to conventional therapy
    • Tenti S, Guidelli GM, Bellisai F, Galeazzi M, Fioravanti A. Long-term treatment of antiphospholipid syndrome with intravenous immunoglobulin in addition to conventional therapy. Clin Exp Rheumatol. 2013;31:877–82.
    • (2013) Clin Exp Rheumatol , vol.31 , pp. 877-882
    • Tenti, S.1    Guidelli, G.M.2    Bellisai, F.3    Galeazzi, M.4    Fioravanti, A.5
  • 67
    • 84994691777 scopus 로고    scopus 로고
    • Repeated low-dose courses of rituximab in SLE-associated antiphospholipid syndrome: data from a tertiary dedicated centre
    • Emmi G, Urban ML, Scalera A, Becatti M, Fiorillo C, Silvestri E, et al. Repeated low-dose courses of rituximab in SLE-associated antiphospholipid syndrome: data from a tertiary dedicated centre. Semin Arthritis Rheum. 2017;46:e21–3.
    • (2017) Semin Arthritis Rheum , vol.46 , pp. e21-e23
    • Emmi, G.1    Urban, M.L.2    Scalera, A.3    Becatti, M.4    Fiorillo, C.5    Silvestri, E.6    Prisco, D.7
  • 68
    • 84961139147 scopus 로고    scopus 로고
    • Rituximab usage in systemic lupus erythematosus-associated antiphospholipid syndrome: a single-center experience
    • COI: 1:CAS:528:DC%2BC28Xks1entbk%3D
    • Wang CR, Liu MF. Rituximab usage in systemic lupus erythematosus-associated antiphospholipid syndrome: a single-center experience. Semin Arthritis Rheum. 2016;46:102–8.
    • (2016) Semin Arthritis Rheum , vol.46 , pp. 102-108
    • Wang, C.R.1    Liu, M.F.2
  • 69
    • 84873846125 scopus 로고    scopus 로고
    • A pilot open-label phase II trial of rituximab for non-criteria manifestations of antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC3sXhsFCjurY%3D
    • Erkan D, Vega J, Ramón G, Kozora E, Lockshin MD. A pilot open-label phase II trial of rituximab for non-criteria manifestations of antiphospholipid syndrome. Arthritis Rheum. 2013;65:464–71.
    • (2013) Arthritis Rheum , vol.65 , pp. 464-471
    • Erkan, D.1    Vega, J.2    Ramón, G.3    Kozora, E.4    Lockshin, M.D.5
  • 70
    • 85015173401 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation in Systemic Lupus Erythematosus and antiphospholipid syndrome: A systematic review
    • This review considered 25 studies (including 279 SLE patients and 54 cases with APS) analyzing the efficacy of HSCT: aPL negativization was reported in 9% in the APS patients and 73% of APS were able to discontinue anticoagulation after HSC
    • • Leone A, Radin M, Almarzooqi AM, Al-Saleh J, Roccatello D, Sciascia S, et al. Autologous hematopoietic stem cell transplantation in Systemic Lupus Erythematosus and antiphospholipid syndrome: A systematic review. Autoimmun Rev. 2017;16:469–77. This review considered 25 studies (including 279 SLE patients and 54 cases with APS) analyzing the efficacy of HSCT: aPL negativization was reported in 9% in the APS patients and 73% of APS were able to discontinue anticoagulation after HSC.
    • (2017) Autoimmun Rev , vol.16 , pp. 469-477
    • Leone, A.1    Radin, M.2    Almarzooqi, A.M.3    Al-Saleh, J.4    Roccatello, D.5    Sciascia, S.6    Khamashta, M.7
  • 71
    • 84857190406 scopus 로고    scopus 로고
    • Eculizumab in acute recurrence of thrombotic microangiopathy after renal transplantation
    • COI: 1:CAS:528:DC%2BC3MXhsFCmtLvM
    • Hadaya K, Ferrari-Lacraz S, Fumeaux D, Boehlen F, Toso C, Moll S, et al. Eculizumab in acute recurrence of thrombotic microangiopathy after renal transplantation. Am J Transplant. 2011;11:2523–7.
    • (2011) Am J Transplant , vol.11 , pp. 2523-2527
    • Hadaya, K.1    Ferrari-Lacraz, S.2    Fumeaux, D.3    Boehlen, F.4    Toso, C.5    Moll, S.6
  • 72
    • 84917728306 scopus 로고    scopus 로고
    • Efficacy of eculizumab in a patient with immunoadsorption-dependent catastrophic antiphospholipid syndrome: a case report
    • COI: 1:CAS:528:DC%2BC2cXitVKrsbnL
    • Kronbichler A, Frank R, Kirschfink M, Szilágyi Á, Csuka D, Prohászka Z, et al. Efficacy of eculizumab in a patient with immunoadsorption-dependent catastrophic antiphospholipid syndrome: a case report. Medicine (Baltimore). 2014;93:e143.
    • (2014) Medicine (Baltimore) , vol.93
    • Kronbichler, A.1    Frank, R.2    Kirschfink, M.3    Szilágyi, Á.4    Csuka, D.5    Prohászka, Z.6
  • 73
    • 85029439527 scopus 로고    scopus 로고
    • Use of eculizumab in a systemic lupus erythemathosus patient presenting thrombotic microangiopathy and heterozygous deletion in CFHR1-CFHR3. A case report and systematic review
    • de Holanda MI, Pôrto LC, Wagner T, Christiani LF, Palma LMP. Use of eculizumab in a systemic lupus erythemathosus patient presenting thrombotic microangiopathy and heterozygous deletion in CFHR1-CFHR3. A case report and systematic review. Clin Rheumatol. 2017; https://doi.org/10.1007/s10067-017-3823-2.
    • (2017) Clin Rheumatol
    • de Holanda, M.I.1    Pôrto, L.C.2    Wagner, T.3    Christiani, L.F.4    Palma, L.M.P.5
  • 74
    • 84889887563 scopus 로고    scopus 로고
    • Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways
    • COI: 1:CAS:528:DC%2BC3sXhs12ktr%2FK
    • Zhou H, Sheng L, Wang H, Xie H, Mu Y, Wang T, et al. Anti-β2GPI/β2GPI stimulates activation of THP-1 cells through TLR4/MD-2/MyD88 and NF-κB signaling pathways. Thromb Res. 2013;132:742–9.
    • (2013) Thromb Res , vol.132 , pp. 742-749
    • Zhou, H.1    Sheng, L.2    Wang, H.3    Xie, H.4    Mu, Y.5    Wang, T.6    Yan, J.7
  • 75
    • 34547218488 scopus 로고    scopus 로고
    • Anti-beta2GPI-antibody-induced endothelial cell gene expression profiling reveals induction of novel pro-inflammatory genes potentially involved in primary antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BD2sXpsF2qsLw%3D
    • Hamid C, Norgate K, D'Cruz DP, Khamashta MA, Arno M, Pearson JD, et al. Anti-beta2GPI-antibody-induced endothelial cell gene expression profiling reveals induction of novel pro-inflammatory genes potentially involved in primary antiphospholipid syndrome. Ann Rheum Dis. 2007;66:1000–7.
    • (2007) Ann Rheum Dis , vol.66 , pp. 1000-1007
    • Hamid, C.1    Norgate, K.2    D'Cruz, D.P.3    Khamashta, M.A.4    Arno, M.5    Pearson, J.D.6
  • 76
    • 84875919356 scopus 로고    scopus 로고
    • Both NF-κB and c-Jun/AP-1 involved in anti-β2GPI/β2GPI-induced tissue factor expression in monocytes
    • COI: 1:CAS:528:DC%2BC3sXmsVGmsrg%3D
    • Xia L, Zhou H, Hu L, Xie H, Wang T, Xu Y, et al. Both NF-κB and c-Jun/AP-1 involved in anti-β2GPI/β2GPI-induced tissue factor expression in monocytes. Thromb Haemost. 2013;109:643–51.
    • (2013) Thromb Haemost , vol.109 , pp. 643-651
    • Xia, L.1    Zhou, H.2    Hu, L.3    Xie, H.4    Wang, T.5    Xu, Y.6
  • 77
    • 84866239340 scopus 로고    scopus 로고
    • Activation of MAPKs in the anti-β2GPI/β2GPI-induced tissue factor expression through TLR4/IRAKs pathway in THP-1 cells
    • COI: 1:CAS:528:DC%2BC38Xht1yqu7%2FK
    • Zhou H, Chen D, Xie H, Xia L, Wang T, Yuan W, et al. Activation of MAPKs in the anti-β2GPI/β2GPI-induced tissue factor expression through TLR4/IRAKs pathway in THP-1 cells. Thromb Res. 2012;130:e229–35.
    • (2012) Thromb Res , vol.130 , pp. e229-e235
    • Zhou, H.1    Chen, D.2    Xie, H.3    Xia, L.4    Wang, T.5    Yuan, W.6    Yan, J.7
  • 78
    • 85024384842 scopus 로고    scopus 로고
    • Activation of mTOR is involved in anti-β2GPI/β2GPI-induced expression of tissue factor and IL-8 in monocytes
    • COI: 1:CAS:528:DC%2BC2sXht1SjsLnM
    • Xia L, Zhou H, Wang T, Xie Y, Wang T, Wang X, et al. Activation of mTOR is involved in anti-β2GPI/β2GPI-induced expression of tissue factor and IL-8 in monocytes. Thromb Res. 2017;157:103–10.
    • (2017) Thromb Res , vol.157 , pp. 103-110
    • Xia, L.1    Zhou, H.2    Wang, T.3    Xie, Y.4    Wang, T.5    Wang, X.6    Yan, J.7
  • 79
    • 77950377251 scopus 로고    scopus 로고
    • Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression
    • COI: 1:CAS:528:DC%2BC3cXntleruw%3D%3D
    • Mak A, Cheung MW, Cheak AA, Ho RC. Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression. Rheumatology (Oxford, England). 2010;49:281–8.
    • (2010) Rheumatology (Oxford, England) , vol.49 , pp. 281-288
    • Mak, A.1    Cheung, M.W.2    Cheak, A.A.3    Ho, R.C.4
  • 80
    • 77952981639 scopus 로고    scopus 로고
    • Heparin treatment in antiphospholipid syndrome with recurrent pregnancy loss: a systematic review and meta-analysis
    • Ziakas PD, Pavlou M, Voulgarelis M. Heparin treatment in antiphospholipid syndrome with recurrent pregnancy loss: a systematic review and meta-analysis. Obstet Gynecol. 2010;115:1256–62.
    • (2010) Obstet Gynecol , vol.115 , pp. 1256-1262
    • Ziakas, P.D.1    Pavlou, M.2    Voulgarelis, M.3
  • 81
    • 84902193546 scopus 로고    scopus 로고
    • 14th International Congress on Antiphospholipid Antibodies Task Force report on obstetric antiphospholipid syndrome
    • de Jesus GR, Agmon-Levin N, Andrade CA, Andreoli L, Chighizola CB, Porter TF, et al. 14th International Congress on Antiphospholipid Antibodies Task Force report on obstetric antiphospholipid syndrome. Autoimmun Rev. 2014;13:795–813.
    • (2014) Autoimmun Rev , vol.13 , pp. 795-813
    • de Jesus, G.R.1    Agmon-Levin, N.2    Andrade, C.A.3    Andreoli, L.4    Chighizola, C.B.5    Porter, T.F.6
  • 82
    • 84979642523 scopus 로고    scopus 로고
    • EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC1cXjt1ahsbs%3D, Recent European recommendations as guidelines for rheumatologists and gynecologists
    • •• Andreoli L, Bertsias GK, Agmon-Levin N, Brown S, Cervera R, Costedoat-Chalumeau N, et al. EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome. Ann Rheum Dis. 2017;76:476–85. Recent European recommendations as guidelines for rheumatologists and gynecologists.
    • (2017) Ann Rheum Dis , vol.76 , pp. 476-485
    • Andreoli, L.1    Bertsias, G.K.2    Agmon-Levin, N.3    Brown, S.4    Cervera, R.5    Costedoat-Chalumeau, N.6
  • 83
    • 79959504067 scopus 로고    scopus 로고
    • First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss
    • COI: 1:CAS:528:DC%2BC3MXoslChsbc%3D
    • Bramham K, Thomas M, Nelson-Piercy C, Khamashta M, Hunt J. First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss. Blood. 2011;117:6948–51.
    • (2011) Blood , vol.117 , pp. 6948-6951
    • Bramham, K.1    Thomas, M.2    Nelson-Piercy, C.3    Khamashta, M.4    Hunt, J.5
  • 84
    • 84908528863 scopus 로고    scopus 로고
    • Treatment strategies and pregnancy outcomes in antiphospholipid syndrome patients with thrombosis and triple antiphospholipid positivity. A European multicentre retrospective study
    • Ruffatti A, Salvan E, Del Ross T, Gerosa M, Andreoli L, Maina A, et al. Treatment strategies and pregnancy outcomes in antiphospholipid syndrome patients with thrombosis and triple antiphospholipid positivity. A European multicentre retrospective study. Thromb Haemost. 2014;112:727–35.
    • (2014) Thromb Haemost , vol.112 , pp. 727-735
    • Ruffatti, A.1    Salvan, E.2    Del Ross, T.3    Gerosa, M.4    Andreoli, L.5    Maina, A.6
  • 85
    • 84976318983 scopus 로고    scopus 로고
    • Additional treatments for high-risk obstetric antiphospholipid syndrome: a comprehensive review
    • Ruffatti A, Hoxha A, Favaro M, Tonello M, Colpo A, Cucchini U, et al. Additional treatments for high-risk obstetric antiphospholipid syndrome: a comprehensive review. Clin Rev Allergy Immunol. 2017;5:28–39.
    • (2017) Clin Rev Allergy Immunol , vol.5 , pp. 28-39
    • Ruffatti, A.1    Hoxha, A.2    Favaro, M.3    Tonello, M.4    Colpo, A.5    Cucchini, U.6
  • 87
    • 84965056655 scopus 로고    scopus 로고
    • Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC28XnsVChtb4%3D
    • Bertolaccini ML, Contento G, Lennen R, Sanna G, Blower PJ, Ma MT, et al. Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome. J Autoimmun. 2016;75:30–8.
    • (2016) J Autoimmun , vol.75 , pp. 30-38
    • Bertolaccini, M.L.1    Contento, G.2    Lennen, R.3    Sanna, G.4    Blower, P.J.5    Ma, M.T.6
  • 88
    • 84995578428 scopus 로고    scopus 로고
    • Prevention & treatment of obstetrical complications in APS: is hydroxychloroquine the holy grail we are looking for?
    • COI: 1:CAS:528:DC%2BC28Xht12jtb3N
    • Meroni PL. Prevention & treatment of obstetrical complications in APS: is hydroxychloroquine the holy grail we are looking for? J Autoimmun. 2016;75:1–5.
    • (2016) J Autoimmun , vol.75 , pp. 1-5
    • Meroni, P.L.1
  • 89
    • 84933670410 scopus 로고    scopus 로고
    • The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: data from a European multicenter retrospective study
    • COI: 1:CAS:528:DC%2BC2MXhsVGms7g%3D
    • Mekinian A, Lazzaroni MG, Kuzenko A, Alijotas-Reig J, Ruffatti A, Levy P, et al. The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: data from a European multicenter retrospective study. Autoimmun Rev. 2015;14:498–502.
    • (2015) Autoimmun Rev , vol.14 , pp. 498-502
    • Mekinian, A.1    Lazzaroni, M.G.2    Kuzenko, A.3    Alijotas-Reig, J.4    Ruffatti, A.5    Levy, P.6
  • 90
    • 84957565813 scopus 로고    scopus 로고
    • The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment
    • Sciascia S, Branch DW, Levy RA, Middeldorp S, Pavord S, Roccatello D, et al. The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment. Thromb Haemost. 2016;115:285–90.
    • (2016) Thromb Haemost , vol.115 , pp. 285-290
    • Sciascia, S.1    Branch, D.W.2    Levy, R.A.3    Middeldorp, S.4    Pavord, S.5    Roccatello, D.6
  • 91
    • 85019168322 scopus 로고    scopus 로고
    • Refractory obstetrical antiphospholipid syndrome: features, treatment and outcome in a European multicenter retrospective study
    • Mekinian A, Alijotas-Reig J, Carrat F, Costedoat-Chalumeau N, Ruffatti A, Lazzaroni MG, et al. Refractory obstetrical antiphospholipid syndrome: features, treatment and outcome in a European multicenter retrospective study. Autoimmun Rev. 2017;16:730–4.
    • (2017) Autoimmun Rev , vol.16 , pp. 730-734
    • Mekinian, A.1    Alijotas-Reig, J.2    Carrat, F.3    Costedoat-Chalumeau, N.4    Ruffatti, A.5    Lazzaroni, M.G.6
  • 92
    • 85020704652 scopus 로고    scopus 로고
    • HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) protocol: a multinational randomized controlled trial of hydroxychloroquine versus placebo in addition to standard treatment in pregnant women with antiphospholipid syndrome or antibodies
    • COI: 1:CAS:528:DC%2BC2sXpvVKlu7Y%3D
    • Schreiber K, Breen K, Cohen H, Jacobsen S, Middeldorp S, Pavord S, et al. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) protocol: a multinational randomized controlled trial of hydroxychloroquine versus placebo in addition to standard treatment in pregnant women with antiphospholipid syndrome or antibodies. Semin Thromb Hemost. 2017;43:562–71.
    • (2017) Semin Thromb Hemost , vol.43 , pp. 562-571
    • Schreiber, K.1    Breen, K.2    Cohen, H.3    Jacobsen, S.4    Middeldorp, S.5    Pavord, S.6
  • 93
    • 84959378744 scopus 로고    scopus 로고
    • The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation
    • Gotestam Skorpen C, Hoeltzenbein M, Tincani A, Fischer-Betz R, Elefant E, Chambers C, et al. The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation. Ann Rheum Dis. 2016;75:795–810.
    • (2016) Ann Rheum Dis , vol.75 , pp. 795-810
    • Gotestam Skorpen, C.1    Hoeltzenbein, M.2    Tincani, A.3    Fischer-Betz, R.4    Elefant, E.5    Chambers, C.6
  • 94
    • 84987837104 scopus 로고    scopus 로고
    • Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy
    • Lefkou E, Mamopoulos A, Dagklis T, Vosnakis C, Rousso D, Girardi G. Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy. J Clin Invest. 2016;126:2933–40.
    • (2016) J Clin Invest , vol.126 , pp. 2933-2940
    • Lefkou, E.1    Mamopoulos, A.2    Dagklis, T.3    Vosnakis, C.4    Rousso, D.5    Girardi, G.6
  • 95
    • 84937717879 scopus 로고    scopus 로고
    • Prevention of defective placentation and pregnancy loss by blocking innate immune pathways in a syngeneic model of placental insufficiency
    • COI: 1:CAS:528:DC%2BC2MXhtFyjtrbO
    • Gelber SE, Brent E, Redecha P, Perino G, Tomlinson S, Davisson RL, et al. Prevention of defective placentation and pregnancy loss by blocking innate immune pathways in a syngeneic model of placental insufficiency. J Immunol (Baltimore, Md: 1950). 2015;195:1129–38.
    • (2015) J Immunol (Baltimore, Md: 1950) , vol.195 , pp. 1129-1138
    • Gelber, S.E.1    Brent, E.2    Redecha, P.3    Perino, G.4    Tomlinson, S.5    Davisson, R.L.6
  • 96
    • 85016000707 scopus 로고    scopus 로고
    • Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: a case report
    • Gustavsen A, Skattum L, Bergseth G, Lorentzen B, Floisand Y, Bosnes V, et al. Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: a case report. Medicine. 2017;96:e6338.
    • (2017) Medicine , vol.96
    • Gustavsen, A.1    Skattum, L.2    Bergseth, G.3    Lorentzen, B.4    Floisand, Y.5    Bosnes, V.6
  • 97
    • 84941276223 scopus 로고    scopus 로고
    • Eculizumab in pregnant patients with paroxysmal nocturnal hemoglobinuria
    • COI: 1:CAS:528:DC%2BC28XkvFOitA%3D%3D
    • Kelly RJ, Hochsmann B, Szer J, Kulasekararaj A, de Guibert S, Roth A, et al. Eculizumab in pregnant patients with paroxysmal nocturnal hemoglobinuria. N Engl J Med. 2015;373:1032–9.
    • (2015) N Engl J Med , vol.373 , pp. 1032-1039
    • Kelly, R.J.1    Hochsmann, B.2    Szer, J.3    Kulasekararaj, A.4    de Guibert, S.5    Roth, A.6
  • 98
    • 84884205055 scopus 로고    scopus 로고
    • Antiphospholipid antibodies affect human endometrial angiogenesis: protective effect of a synthetic peptide (TIFI) mimicking the phospholipid binding site of beta(2) glycoprotein I
    • Di Simone N, D'Ippolito S, Marana R, Di Nicuolo F, Castellani R, Pierangeli SS, et al. Antiphospholipid antibodies affect human endometrial angiogenesis: protective effect of a synthetic peptide (TIFI) mimicking the phospholipid binding site of beta(2) glycoprotein I. Am J Reprod Immunol (New York, NY: 1989). 2013;70:299–308.
    • (2013) Am J Reprod Immunol (New York, NY: 1989) , vol.70 , pp. 299-308
    • Di Simone, N.1    D'Ippolito, S.2    Marana, R.3    Di Nicuolo, F.4    Castellani, R.5    Pierangeli, S.S.6
  • 99
    • 84901705578 scopus 로고    scopus 로고
    • A non-complement-fixing antibody to beta2 glycoprotein I as a novel therapy for antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2cXhtVSgu7fN
    • Agostinis C, Durigutto P, Sblattero D, Borghi MO, Grossi C, Guida F, et al. A non-complement-fixing antibody to beta2 glycoprotein I as a novel therapy for antiphospholipid syndrome. Blood. 2014;123:3478–87.
    • (2014) Blood , vol.123 , pp. 3478-3487
    • Agostinis, C.1    Durigutto, P.2    Sblattero, D.3    Borghi, M.O.4    Grossi, C.5    Guida, F.6
  • 100
    • 85024388342 scopus 로고    scopus 로고
    • Identification of a monoclonal antibody that attenuates antiphospholipid syndrome-related pregnancy complications and thrombosis
    • Mineo C, Lanier L, Jung E, Sengupta S, Ulrich V, Sacharidou A, et al. Identification of a monoclonal antibody that attenuates antiphospholipid syndrome-related pregnancy complications and thrombosis. PLoS One. 2016;11:e0158757.
    • (2016) PLoS One , vol.11
    • Mineo, C.1    Lanier, L.2    Jung, E.3    Sengupta, S.4    Ulrich, V.5    Sacharidou, A.6
  • 101
    • 84908476494 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells specific for beta2-glycoprotein-I domain-I, attenuate experimental antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC2cXhvVWmsrbP
    • Zandman-Goddard G, Pierangeli SS, Gertel S, Blank M. Tolerogenic dendritic cells specific for beta2-glycoprotein-I domain-I, attenuate experimental antiphospholipid syndrome. J Autoimmun. 2014;54:72–80.
    • (2014) J Autoimmun , vol.54 , pp. 72-80
    • Zandman-Goddard, G.1    Pierangeli, S.S.2    Gertel, S.3    Blank, M.4
  • 102
    • 84893089265 scopus 로고    scopus 로고
    • Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study
    • COI: 1:CAS:528:DC%2BC2cXhvVSksbc%3D
    • Bouvier S, Cochery-Nouvellon E, Lavigne-Lissalde G, Mercier E, Marchetti T, Balducchi JP, et al. Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study. Blood. 2014;123:404–13.
    • (2014) Blood , vol.123 , pp. 404-413
    • Bouvier, S.1    Cochery-Nouvellon, E.2    Lavigne-Lissalde, G.3    Mercier, E.4    Marchetti, T.5    Balducchi, J.P.6
  • 103
  • 104
    • 3442901073 scopus 로고    scopus 로고
    • Antiphospholipid syndrome and asymptomatic carriers of antiphospholipid antibody: prospective analysis of 404 individuals
    • Giron-Gonzalez JA, Garcia del Rio E, Rodriguez C, Rodriguez-Martorell J, Serrano A. Antiphospholipid syndrome and asymptomatic carriers of antiphospholipid antibody: prospective analysis of 404 individuals. J Rheumatol 2004;31:1560–1567.
    • (2004) J Rheumatol , vol.31 , pp. 1560-1567
    • Giron-Gonzalez, J.A.1    Garcia del Rio, E.2    Rodriguez, C.3    Rodriguez-Martorell, J.4    Serrano, A.5
  • 105
    • 74849134126 scopus 로고    scopus 로고
    • Pregnancy outcome in different clinical phenotypes of antiphospholipid syndrome
    • COI: 1:STN:280:DC%2BC3c%2FgslSitg%3D%3D
    • Bramham K, Hunt BJ, Germain S, Calatayud I, Khamashta M, Bewley S, et al. Pregnancy outcome in different clinical phenotypes of antiphospholipid syndrome. Lupus. 2010;19:58–64.
    • (2010) Lupus , vol.19 , pp. 58-64
    • Bramham, K.1    Hunt, B.J.2    Germain, S.3    Calatayud, I.4    Khamashta, M.5    Bewley, S.6
  • 106
    • 80051936498 scopus 로고    scopus 로고
    • Risk factors for pregnancy failure in patients with anti-phospholipid syndrome treated with conventional therapies: a multicentre, case-control study
    • COI: 1:CAS:528:DC%2BC3MXhtVynsrvE
    • Ruffatti A, Tonello M, Visentin MS, Bontadi A, Hoxha A, De Carolis S, et al. Risk factors for pregnancy failure in patients with anti-phospholipid syndrome treated with conventional therapies: a multicentre, case-control study. Rheumatology (Oxford, England). 2011;50:1684–9.
    • (2011) Rheumatology (Oxford, England) , vol.50 , pp. 1684-1689
    • Ruffatti, A.1    Tonello, M.2    Visentin, M.S.3    Bontadi, A.4    Hoxha, A.5    De Carolis, S.6
  • 107
    • 84873162417 scopus 로고    scopus 로고
    • Pregnancy outcome in patients with antiphospholipid syndrome after cerebral ischaemic events: an observational study
    • COI: 1:STN:280:DC%2BC38jgsFegtg%3D%3D
    • Fischer-Betz R, Specker C, Brinks R, Schneider M. Pregnancy outcome in patients with antiphospholipid syndrome after cerebral ischaemic events: an observational study. Lupus. 2012;21:1183–9.
    • (2012) Lupus , vol.21 , pp. 1183-1189
    • Fischer-Betz, R.1    Specker, C.2    Brinks, R.3    Schneider, M.4
  • 108
    • 67149087369 scopus 로고    scopus 로고
    • Determinants of risk for venous and arterial thrombosis in primary antiphospholipid syndrome and in antiphospholipid syndrome with systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BD1MXotlSjt7k%3D
    • Danowski A, de Azevedo MN, de Souza Papi JA, Petri M. Determinants of risk for venous and arterial thrombosis in primary antiphospholipid syndrome and in antiphospholipid syndrome with systemic lupus erythematosus. J Rheumatol. 2009;36:1195–9.
    • (2009) J Rheumatol , vol.36 , pp. 1195-1199
    • Danowski, A.1    de Azevedo, M.N.2    de Souza Papi, J.A.3    Petri, M.4
  • 109
    • 84863197776 scopus 로고    scopus 로고
    • Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies
    • COI: 1:CAS:528:DC%2BC38XptFCnsr0%3D
    • Lockshin MD, Kim M, Laskin CA, Guerra M, Branch DW, Merrill J, et al. Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies. Arthritis Rheum. 2012;64:2311–8.
    • (2012) Arthritis Rheum , vol.64 , pp. 2311-2318
    • Lockshin, M.D.1    Kim, M.2    Laskin, C.A.3    Guerra, M.4    Branch, D.W.5    Merrill, J.6
  • 110
    • 84980686894 scopus 로고    scopus 로고
    • Lupus anticoagulant is the main predictor of adverse pregnancy outcomes in aPL-positive patients: validation of PROMISSE study results
    • Yelnik CM, Laskin CA, Porter TF, Branch DW, Buyon JP, Guerra MM, et al. Lupus anticoagulant is the main predictor of adverse pregnancy outcomes in aPL-positive patients: validation of PROMISSE study results. Lupus Sci Med. 2016;3:e000131.
    • (2016) Lupus Sci Med , vol.3
    • Yelnik, C.M.1    Laskin, C.A.2    Porter, T.F.3    Branch, D.W.4    Buyon, J.P.5    Guerra, M.M.6
  • 111
    • 85015780849 scopus 로고    scopus 로고
    • Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study
    • Saccone G, Berghella V, Maruotti GM, Ghi T, Rizzo G, Simonazzi G, et al. Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study. Am J Obstet Gynecol. 2017;216:525.e1-.e12.
    • (2017) Am J Obstet Gynecol , vol.216
    • Saccone, G.1    Berghella, V.2    Maruotti, G.M.3    Ghi, T.4    Rizzo, G.5    Simonazzi, G.6
  • 112
    • 81355123254 scopus 로고    scopus 로고
    • High positive antibody titers and adverse pregnancy outcome in women with antiphospholipid syndrome
    • Simchen MJ, Dulitzki M, Rofe G, Shani H, Langevitz P, Schiff E, et al. High positive antibody titers and adverse pregnancy outcome in women with antiphospholipid syndrome. Acta Obstet Gynecol Scand. 2011;90:1428–33.
    • (2011) Acta Obstet Gynecol Scand , vol.90 , pp. 1428-1433
    • Simchen, M.J.1    Dulitzki, M.2    Rofe, G.3    Shani, H.4    Langevitz, P.5    Schiff, E.6
  • 113
    • 84924366763 scopus 로고    scopus 로고
    • Clinical features and pregnancy outcome in antiphospholipid syndrome patients with history of severe pregnancy complications
    • COI: 1:CAS:528:DC%2BC2MXktVeks7k%3D
    • Matsuki Y, Atsumi T, Yamaguchi K, Hisano M, Arata N, Oku K, et al. Clinical features and pregnancy outcome in antiphospholipid syndrome patients with history of severe pregnancy complications. Mod Rheumatol / Jpn Rheum Assoc. 2015;25:215–8.
    • (2015) Mod Rheumatol / Jpn Rheum Assoc , vol.25 , pp. 215-218
    • Matsuki, Y.1    Atsumi, T.2    Yamaguchi, K.3    Hisano, M.4    Arata, N.5    Oku, K.6
  • 114
    • 84995665659 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis of 500 patients from the International CAPS Registry
    • Multicenter registry on 500 APS patients encountering 522 CAPS episodes: triggers, clinical presentation and mortality rate
    • • Rodríguez-Pintó I, Moitinho M, Santacreu I, Shoenfeld Y, Erkan D, Espinosa G, et al. Catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis of 500 patients from the International CAPS Registry. Autoimmun Rev. 2016;15:1120–4. Multicenter registry on 500 APS patients encountering 522 CAPS episodes: triggers, clinical presentation and mortality rate.
    • (2016) Autoimmun Rev , vol.15 , pp. 1120-1124
    • Rodríguez-Pintó, I.1    Moitinho, M.2    Santacreu, I.3    Shoenfeld, Y.4    Erkan, D.5    Espinosa, G.6
  • 115
    • 0035162625 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: clues to the pathogenesis from a series of 80 patients
    • COI: 1:STN:280:DC%2BD3MnnvFWmtg%3D%3D
    • Asherson RA, Cervera R, Piette JC, Shoenfeld Y, Espinosa G, Petri MA, et al. Catastrophic antiphospholipid syndrome: clues to the pathogenesis from a series of 80 patients. Medicine (Baltimore). 2001;80:355–77.
    • (2001) Medicine (Baltimore) , vol.80 , pp. 355-377
    • Asherson, R.A.1    Cervera, R.2    Piette, J.C.3    Shoenfeld, Y.4    Espinosa, G.5    Petri, M.A.6
  • 116
    • 33746993589 scopus 로고    scopus 로고
    • European Forum on Antiphospholipid Antibodies. Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors in a series of 250 patients
    • Bucciarelli S, Espinosa G, Cervera R, Erkan D, Gómez-Puerta JA, Ramos-Casals M, et al. European Forum on Antiphospholipid Antibodies. Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors in a series of 250 patients. Arthritis Rheum. 2006;54:2568–76.
    • (2006) Arthritis Rheum , vol.54 , pp. 2568-2576
    • Bucciarelli, S.1    Espinosa, G.2    Cervera, R.3    Erkan, D.4    Gómez-Puerta, J.A.5    Ramos-Casals, M.6    Font, J.7    Asherson, R.A.8
  • 117
    • 84867749740 scopus 로고    scopus 로고
    • 8th international congress on autoimmunity: new perspectives for refractory catastrophic antiphospholipid syndrome
    • COI: 1:CAS:528:DC%2BC38XhsFagsrnP
    • Cervera R. 8th international congress on autoimmunity: new perspectives for refractory catastrophic antiphospholipid syndrome. Expert Rev Clin Immunol. 2012;8:617–9.
    • (2012) Expert Rev Clin Immunol , vol.8 , pp. 617-619
    • Cervera, R.1
  • 118
    • 33846971949 scopus 로고    scopus 로고
    • Catastrophic Antiphospholipid Syndrome Project Group. The clinical spectrum of catastrophic antiphospholipid syndrome in the absence and presence of lupus
    • Bayraktar UD, Erkan D, Bucciarelli S, Espinosa G, Asherson R. Catastrophic Antiphospholipid Syndrome Project Group. The clinical spectrum of catastrophic antiphospholipid syndrome in the absence and presence of lupus. J Rheumatol. 2007;34:346–52.
    • (2007) J Rheumatol , vol.34 , pp. 346-352
    • Bayraktar, U.D.1    Erkan, D.2    Bucciarelli, S.3    Espinosa, G.4    Asherson, R.5
  • 119
    • 84881551069 scopus 로고    scopus 로고
    • Catastrophic Antiphospholipid Syndrome (CAPS) Registry Project Group (European Forum on Antiphospholipid Antibodies). Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximab
    • COI: 1:CAS:528:DC%2BC3sXhtFShsrfK
    • Berman H, Rodríguez-Pintó I, Cervera R, Morel N, Costedoat-Chalumeau N, Erkan D, et al. Catastrophic Antiphospholipid Syndrome (CAPS) Registry Project Group (European Forum on Antiphospholipid Antibodies). Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximab. Autoimmun Rev. 2013;12:1085–90.
    • (2013) Autoimmun Rev , vol.12 , pp. 1085-1090
    • Berman, H.1    Rodríguez-Pintó, I.2    Cervera, R.3    Morel, N.4    Costedoat-Chalumeau, N.5    Erkan, D.6    Shoenfeld, Y.7    Espinosa, G.8
  • 120
    • 84922115374 scopus 로고    scopus 로고
    • Rituximab and its therapeutic potential in catastrophic antiphospolipid syndrome
    • Rodríguez-Pintó I, Cervera R, Espinosa G. Rituximab and its therapeutic potential in catastrophic antiphospolipid syndrome. Ther Adv Musculoskelet Dis. 2015;7:26–30.
    • (2015) Ther Adv Musculoskelet Dis , vol.7 , pp. 26-30
    • Rodríguez-Pintó, I.1    Cervera, R.2    Espinosa, G.3
  • 121
    • 84991380084 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus treated with rituximab: case report and a review of the literature
    • COI: 1:STN:280:DC%2BC2Mnlt1KntA%3D%3D
    • Sukara G, Baresic M, Sentic M, Brcic L, Anic B. Catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus treated with rituximab: case report and a review of the literature. Acta Reumatol Port. 2015;40:169–75.
    • (2015) Acta Reumatol Port , vol.40 , pp. 169-175
    • Sukara, G.1    Baresic, M.2    Sentic, M.3    Brcic, L.4    Anic, B.5
  • 122
    • 85020844051 scopus 로고    scopus 로고
    • A novel 2-stage approach that detects complement activation in patients with antiphospholipid antibody syndrome
    • COI: 1:CAS:528:DC%2BC2sXhtVanu7bK
    • Rand JH, Wu XX, Wolgast LR, Lei V, Conway EM. A novel 2-stage approach that detects complement activation in patients with antiphospholipid antibody syndrome. Thromb Res. 2017;156:119–25.
    • (2017) Thromb Res , vol.156 , pp. 119-125
    • Rand, J.H.1    Wu, X.X.2    Wolgast, L.R.3    Lei, V.4    Conway, E.M.5
  • 123
    • 84988643327 scopus 로고    scopus 로고
    • Autoantibodies against a complement component 1 q subcomponent contribute to complement activation and recurrent thrombosis/pregnancy morbidity in anti-phospholipid syndrome
    • COI: 1:CAS:528:DC%2BC1cXosVan
    • Oku K, Amengual O, Hisada R, Ohmura K, Nakagawa I, Watanabe T, et al. Autoantibodies against a complement component 1 q subcomponent contribute to complement activation and recurrent thrombosis/pregnancy morbidity in anti-phospholipid syndrome. Rheumatology (Oxford). 2016;55:1403–11.
    • (2016) Rheumatology (Oxford) , vol.55 , pp. 1403-1411
    • Oku, K.1    Amengual, O.2    Hisada, R.3    Ohmura, K.4    Nakagawa, I.5    Watanabe, T.6
  • 125
    • 84864485595 scopus 로고    scopus 로고
    • Brief report: induction of sustained remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab
    • COI: 1:CAS:528:DC%2BC38XhtV2gtLfN
    • Shapira I, Andrade D, Allen SL, Salmon JE. Brief report: induction of sustained remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab. Arthritis Rheum. 2012;64:2719–23.
    • (2012) Arthritis Rheum , vol.64 , pp. 2719-2723
    • Shapira, I.1    Andrade, D.2    Allen, S.L.3    Salmon, J.E.4
  • 126
    • 79953692094 scopus 로고    scopus 로고
    • Successful treatment of a case of catastrophic antiphospholipid syndrome with autologous BMT: case report and review of literature
    • COI: 1:CAS:528:DC%2BC3MXkt1Wqtrg%3D
    • Owaidah TM, Maghrabi K, Elkarouri MA, Al Mohareeb F, Al Harthi A, Al ZH. Successful treatment of a case of catastrophic antiphospholipid syndrome with autologous BMT: case report and review of literature. Bone Marrow Transplant. 2011;46:597–600.
    • (2011) Bone Marrow Transplant , vol.46 , pp. 597-600
    • Owaidah, T.M.1    Maghrabi, K.2    Elkarouri, M.A.3    Al Mohareeb, F.4    Al Harthi, A.5    Al, Z.H.6
  • 127
    • 85019215872 scopus 로고    scopus 로고
    • Successful treatment of catastrophic antiphospholipid antibody syndrome associated with MALT lymphoma by autologous hematopoietic stem cell transplantation
    • Oka S, Ono K, Nohgawa M. Successful treatment of catastrophic antiphospholipid antibody syndrome associated with MALT lymphoma by autologous hematopoietic stem cell transplantation. Intern Med. 2017;56:1207–12.
    • (2017) Intern Med , vol.56 , pp. 1207-1212
    • Oka, S.1    Ono, K.2    Nohgawa, M.3
  • 128
    • 85044324004 scopus 로고    scopus 로고
    • Efficacy and safety of autologous haematopoietic stem cell transplantation in systemic sclerosis: a systematic review of literature
    • Eyraud A, Scouppe L, Barnetche T, Forcade E, Lazaro E, Duffau P, et al. Efficacy and safety of autologous haematopoietic stem cell transplantation in systemic sclerosis: a systematic review of literature. Br J Dermatol. 2017;14 https://doi.org/10.1111/bjd.15993.
    • (2017) Br J Dermatol , vol.14
    • Eyraud, A.1    Scouppe, L.2    Barnetche, T.3    Forcade, E.4    Lazaro, E.5    Duffau, P.6
  • 130
    • 84934930787 scopus 로고    scopus 로고
    • Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients
    • COI: 1:CAS:528:DC%2BC28XitFKqtrrP
    • Cervera R, Serrano R, Pons-Estel GJ, Ceberio-Hualde L, Shoenfeld Y, de Ramon E, et al. Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients. Ann Rheum Dis. 2015;74:1011–8.
    • (2015) Ann Rheum Dis , vol.74 , pp. 1011-1018
    • Cervera, R.1    Serrano, R.2    Pons-Estel, G.J.3    Ceberio-Hualde, L.4    Shoenfeld, Y.5    de Ramon, E.6
  • 131
    • 85027836354 scopus 로고    scopus 로고
    • Longterm outcome of patients with primary antiphospholipid syndrome: a retrospective multicenter study
    • Multicenter retrospective study with 115 APS patients with follow-up more than 18 years: clinical features, treatment and evolution
    • • Taraborelli M, Reggia R, Dall'Ara F, Fredi M, Andreoli L, Gerosa M, et al. Longterm outcome of patients with primary antiphospholipid syndrome: a retrospective multicenter study. J Rheumatol. 2017;44:1165–72. Multicenter retrospective study with 115 APS patients with follow-up more than 18 years: clinical features, treatment and evolution.
    • (2017) J Rheumatol , vol.44 , pp. 1165-1172
    • Taraborelli, M.1    Reggia, R.2    Dall'Ara, F.3    Fredi, M.4    Andreoli, L.5    Gerosa, M.6
  • 132
    • 84878370351 scopus 로고    scopus 로고
    • The role of lupus anticoagulant and triple marker positivity as risk factors for rethrombosis in patients with primary antiphospholipid syndrome
    • Hernandez-Molina G, Espericueta-Arriola G, Cabral AR. The role of lupus anticoagulant and triple marker positivity as risk factors for rethrombosis in patients with primary antiphospholipid syndrome. Clin Exp Rheumatol. 2013;31:382–8.
    • (2013) Clin Exp Rheumatol , vol.31 , pp. 382-388
    • Hernandez-Molina, G.1    Espericueta-Arriola, G.2    Cabral, A.R.3
  • 133
    • 84962542199 scopus 로고    scopus 로고
    • Patients with antiphosholipid syndrome and thrombotic recurrences: a real world observation (the Piedmont cohort study)
    • COI: 1:CAS:528:DC%2BC28XpsV2htrY%3D
    • Bazzan M, Vaccarino A, Stella S, Sciascia S, Montaruli B, Bertero MT, et al. Patients with antiphosholipid syndrome and thrombotic recurrences: a real world observation (the Piedmont cohort study). Lupus. 2016;25:479–85.
    • (2016) Lupus , vol.25 , pp. 479-485
    • Bazzan, M.1    Vaccarino, A.2    Stella, S.3    Sciascia, S.4    Montaruli, B.5    Bertero, M.T.6
  • 134
    • 0346688744 scopus 로고    scopus 로고
    • High impact of antiphospholipid syndrome on irreversible organ damage and survival of patients with systemic lupus erythematosus
    • Ruiz-Irastorza G, Egurbide MV, Ugalde J, et al. High impact of antiphospholipid syndrome on irreversible organ damage and survival of patients with systemic lupus erythematosus. Arch Intern Med. 2004;164:77–82.
    • (2004) Arch Intern Med , vol.164 , pp. 77-82
    • Ruiz-Irastorza, G.1    Egurbide, M.V.2    Ugalde, J.3
  • 135
    • 84870371641 scopus 로고    scopus 로고
    • Predictors of organ damage in systemic lupus erythematosus: the Hopkins lupus cohort
    • COI: 1:CAS:528:DC%2BC38Xhsleksr%2FN
    • Petri M, Purvey S, Fang H, Magder LS. Predictors of organ damage in systemic lupus erythematosus: the Hopkins lupus cohort. Arthritis Rheumatism. 2012;64:4021–8.
    • (2012) Arthritis Rheumatism , vol.64 , pp. 4021-4028
    • Petri, M.1    Purvey, S.2    Fang, H.3    Magder, L.S.4
  • 136
    • 10844231837 scopus 로고    scopus 로고
    • Antiphospholipid antibodies predict damage in patients with systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BD2MXpslKhsA%3D%3D
    • Ruiz-Irastorza G, Egurbide MV, Martinez-Berriotxoa A, Ugalde J, Aguirre C. Antiphospholipid antibodies predict damage in patients with systemic lupus erythematosus. Lupus. 2004;13:900–5.
    • (2004) Lupus , vol.13 , pp. 900-905
    • Ruiz-Irastorza, G.1    Egurbide, M.V.2    Martinez-Berriotxoa, A.3    Ugalde, J.4    Aguirre, C.5
  • 137
    • 0042694721 scopus 로고    scopus 로고
    • Accrual of organ damage over time in patients with systemic lupus erythematosus
    • Gladmann DD, Urowitz MB, Rahaman P, Ibanez D, Tam LS. Accrual of organ damage over time in patients with systemic lupus erythematosus. J Rheumatol. 2003;30:1955–9.
    • (2003) J Rheumatol , vol.30 , pp. 1955-1959
    • Gladmann, D.D.1    Urowitz, M.B.2    Rahaman, P.3    Ibanez, D.4    Tam, L.S.5
  • 138
    • 65849310742 scopus 로고    scopus 로고
    • Damage and mortality in a group of British patients with systemic lupus erythematosus followed up for over 10 years
    • Chambers SA, Allen E, Rahman A, Isenberg D. Damage and mortality in a group of British patients with systemic lupus erythematosus followed up for over 10 years. Rheumatology (Oxford). 2009;48:673–5.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 673-675
    • Chambers, S.A.1    Allen, E.2    Rahman, A.3    Isenberg, D.4
  • 140
    • 33746714987 scopus 로고    scopus 로고
    • Damage accumulation in systemic lupus erythematosus and its relation to disease activity and mortality
    • Becker-Merok A, Nossent HC. Damage accumulation in systemic lupus erythematosus and its relation to disease activity and mortality. J Rheumatol. 2006;33:1570–7.
    • (2006) J Rheumatol , vol.33 , pp. 1570-1577
    • Becker-Merok, A.1    Nossent, H.C.2
  • 141
    • 77954074375 scopus 로고    scopus 로고
    • Disease activity and damage accrual during the early disease course in a multinational inception cohort of patients with systemic lupus erythematosus
    • COI: 1:STN:280:DC%2BC3cngtFWrsA%3D%3D
    • Nossent J, Kiss E, Rozman B, Pokorny G, Vlachoyiannopoulos P, Olesinska M, et al. Disease activity and damage accrual during the early disease course in a multinational inception cohort of patients with systemic lupus erythematosus. Lupus. 2010;19:949–56.
    • (2010) Lupus , vol.19 , pp. 949-956
    • Nossent, J.1    Kiss, E.2    Rozman, B.3    Pokorny, G.4    Vlachoyiannopoulos, P.5    Olesinska, M.6
  • 142
    • 0034800173 scopus 로고    scopus 로고
    • Systemic lupus erythematosus in three ethnic groups. VII. Predictors of early mortality in LUMINA cohort. LUMINA study group
    • COI: 1:STN:280:DC%2BD3M3kvFClsg%3D%3D
    • Alarcon GS, McGwin G Jr, Bastian HM, Roseman J, Lisse J, Fessler BJ, et al. Systemic lupus erythematosus in three ethnic groups. VII. Predictors of early mortality in LUMINA cohort. LUMINA study group. Arthritis Rheum. 2001;45:191–202.
    • (2001) Arthritis Rheum , vol.45 , pp. 191-202
    • Alarcon, G.S.1    McGwin, G.2    Bastian, H.M.3    Roseman, J.4    Lisse, J.5    Fessler, B.J.6
  • 143
    • 0344837921 scopus 로고    scopus 로고
    • Association of damage with autoantibody profile, age, race, sex and disease duration in systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BD3sXit1yntLk%3D
    • Yee CS, Hussein H, Skan J, Bowman S, Situnayake D, Gordon C. Association of damage with autoantibody profile, age, race, sex and disease duration in systemic lupus erythematosus. Rheumatology. 2003;42:276–9.
    • (2003) Rheumatology , vol.42 , pp. 276-279
    • Yee, C.S.1    Hussein, H.2    Skan, J.3    Bowman, S.4    Situnayake, D.5    Gordon, C.6
  • 144
    • 0038166875 scopus 로고    scopus 로고
    • Damage accrual in southern Chinese patients with systemic lupus erythematosus
    • Mok CC, Ho CT, Wong RW, Lau CS. Damage accrual in southern Chinese patients with systemic lupus erythematosus. J Rheumatol. 2003;30:1513–9.
    • (2003) J Rheumatol , vol.30 , pp. 1513-1519
    • Mok, C.C.1    Ho, C.T.2    Wong, R.W.3    Lau, C.S.4
  • 145
    • 84924190291 scopus 로고    scopus 로고
    • Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort
    • COI: 1:CAS:528:DC%2BC28XmtFGgur0%3D
    • Bruce IN, O'Kneeffe AG, Farewell V, et al. Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort. Ann Rheum Dis. 2015;74:1706–13.
    • (2015) Ann Rheum Dis , vol.74 , pp. 1706-1713
    • Bruce, I.N.1    O'Kneeffe, A.G.2    Farewell, V.3
  • 146
    • 84988689796 scopus 로고    scopus 로고
    • The contribution of antiphospholipid antibodies to organ damage in systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BC28XhvFaksr3L, The paper analyses whether a clinically significant aPL profile is associated with an increased risk of organ damage accrual during a 15-year follow-up in a cohort of 262 SLE
    • • Taraborelli M, Leuenberger L, Lazzaroni MG, Martinazzi N, Zhang W, Franceschini F, et al. The contribution of antiphospholipid antibodies to organ damage in systemic lupus erythematosus. Lupus. 2016;25:1365–8. The paper analyses whether a clinically significant aPL profile is associated with an increased risk of organ damage accrual during a 15-year follow-up in a cohort of 262 SLE.
    • (2016) Lupus , vol.25 , pp. 1365-1368
    • Taraborelli, M.1    Leuenberger, L.2    Lazzaroni, M.G.3    Martinazzi, N.4    Zhang, W.5    Franceschini, F.6
  • 147
    • 84966564980 scopus 로고    scopus 로고
    • The chronic damage in systemic lupus erythematosus is driven by flares, glucocorticoids and antiphospholipid antibodies: results from a monocentric cohort
    • COI: 1:CAS:528:DC%2BC2sXivFCntbY%3D
    • Conti F, Ceccarelli F, Perricone C, Leccese I, Massaro L, Pacucci VA, et al. The chronic damage in systemic lupus erythematosus is driven by flares, glucocorticoids and antiphospholipid antibodies: results from a monocentric cohort. Lupus. 2016;25:719–26.
    • (2016) Lupus , vol.25 , pp. 719-726
    • Conti, F.1    Ceccarelli, F.2    Perricone, C.3    Leccese, I.4    Massaro, L.5    Pacucci, V.A.6
  • 148
    • 85028994337 scopus 로고    scopus 로고
    • Organ damage accrual and distribution in systemic lupus erythematosus patients followed-up for more than 10 years
    • COI: 1:CAS:528:DC%2BC1cXks1ekug%3D%3D
    • Taraborelli M, Cavazzana I, Martinazzi N, Lazzaroni MG, Fredi M, Andreoli L, et al. Organ damage accrual and distribution in systemic lupus erythematosus patients followed-up for more than 10 years. Lupus. 2017;26:1197–204.
    • (2017) Lupus , vol.26 , pp. 1197-1204
    • Taraborelli, M.1    Cavazzana, I.2    Martinazzi, N.3    Lazzaroni, M.G.4    Fredi, M.5    Andreoli, L.6
  • 149
    • 77951233074 scopus 로고    scopus 로고
    • Antiphospholipid syndrome and the brain in pediatric and adult patients
    • COI: 1:STN:280:DC%2BC3c3isVGgsg%3D%3D
    • Muscal E, Brey RL. Antiphospholipid syndrome and the brain in pediatric and adult patients. Lupus. 2010;19:406–11.
    • (2010) Lupus , vol.19 , pp. 406-411
    • Muscal, E.1    Brey, R.L.2
  • 150
    • 3042797102 scopus 로고    scopus 로고
    • Endothelial cell activation by antiphospholipid antibodies
    • COI: 1:CAS:528:DC%2BD2cXls1eit7w%3D
    • Meroni PL, Raschi E, Testoni C, Borghi MO. Endothelial cell activation by antiphospholipid antibodies. Clin Immunol Orl Fla. 2004;112:169–74.
    • (2004) Clin Immunol Orl Fla , vol.112 , pp. 169-174
    • Meroni, P.L.1    Raschi, E.2    Testoni, C.3    Borghi, M.O.4
  • 151
    • 0025102933 scopus 로고
    • Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: a model for autoimmune fetal loss
    • COI: 1:STN:280:DyaK3czivVajsg%3D%3D
    • Branch DW, Dudley DJ, Mitchell MD, Creighton KA, Abbott TM, Hammond EH, et al. Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: a model for autoimmune fetal loss. Am J Obstet Gynecol. 1990;163:210–6.
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 210-216
    • Branch, D.W.1    Dudley, D.J.2    Mitchell, M.D.3    Creighton, K.A.4    Abbott, T.M.5    Hammond, E.H.6
  • 152
    • 11144229526 scopus 로고    scopus 로고
    • Decreased binding of annexin v to endothelial cells: a potential mechanism in atherothrombosis of patients with systemic lupus erythematosus
    • COI: 1:CAS:528:DC%2BD2cXhtFaiu7nK
    • Cederholm A, Svenungsson E, Jensen-Urstad K, Trollmo C, Ulfgren AK, Swedenborg J, et al. Decreased binding of annexin v to endothelial cells: a potential mechanism in atherothrombosis of patients with systemic lupus erythematosus. Arteriosclr Thromb Vasc Biol. 2005;25:198–203.
    • (2005) Arteriosclr Thromb Vasc Biol , vol.25 , pp. 198-203
    • Cederholm, A.1    Svenungsson, E.2    Jensen-Urstad, K.3    Trollmo, C.4    Ulfgren, A.K.5    Swedenborg, J.6
  • 153
    • 0033834768 scopus 로고    scopus 로고
    • Experimental thrombosis and antiphospholipid antibodies: new insights
    • Pierangeli SS, Gharavi AE, Harris EN. Experimental thrombosis and antiphospholipid antibodies: new insights. J Autoimmun. 2000;15:41–7.
    • (2000) J Autoimmun , vol.15 , pp. 41-47
    • Pierangeli, S.S.1    Gharavi, A.E.2    Harris, E.N.3
  • 154
    • 0037217897 scopus 로고    scopus 로고
    • Thrombogenicity of beta2glycoproteinI-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster
    • COI: 1:CAS:528:DC%2BD3sXhtFWjtQ%3D%3D
    • Jankowski M, Vreys I, Wittevrongel C, Boon D, Vermylen J, Hoylaerts MF, et al. Thrombogenicity of beta2glycoproteinI-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster. Blood. 2003;101:157–62.
    • (2003) Blood , vol.101 , pp. 157-162
    • Jankowski, M.1    Vreys, I.2    Wittevrongel, C.3    Boon, D.4    Vermylen, J.5    Hoylaerts, M.F.6
  • 155
    • 33646481625 scopus 로고    scopus 로고
    • Anticardiolipin and anti-beta2 glycoprotein I antibodies in infants born to mothers with antiphospholipid antibody-positive autoimmune disease: a follow-up study
    • Motta M, Chirico G, Rebaioli CB, Faden D, Lojacono A, Allegri F, et al. Anticardiolipin and anti-beta2 glycoprotein I antibodies in infants born to mothers with antiphospholipid antibody-positive autoimmune disease: a follow-up study. Am J Perinatol. 2006;23:247–51.
    • (2006) Am J Perinatol , vol.23 , pp. 247-251
    • Motta, M.1    Chirico, G.2    Rebaioli, C.B.3    Faden, D.4    Lojacono, A.5    Allegri, F.6
  • 156
    • 84927643275 scopus 로고    scopus 로고
    • Clinical, laboratory, and therapeutic analyses of 21 patients with neonatal thrombosis and antiphospholipid antibodies: a literature review
    • Peixoto MV, de Carvalho JF, Rodrigues CE. Clinical, laboratory, and therapeutic analyses of 21 patients with neonatal thrombosis and antiphospholipid antibodies: a literature review. J Immunol Res. 2014;2014:672603.
    • (2014) J Immunol Res , vol.2014 , pp. 672603
    • Peixoto, M.V.1    de Carvalho, J.F.2    Rodrigues, C.E.3
  • 157
    • 84949109106 scopus 로고    scopus 로고
    • Mice with experimental antiphospholipid syndrome display hippocampal dysfunction and a reduction of dendritic complexity in hippocampal CA1 neurones
    • COI: 1:CAS:528:DC%2BC2MXht1SrsbnI
    • Frauenknecht K, Katzav A, Weiss Lavi R, Sabag A, Otten S, Chapman J, et al. Mice with experimental antiphospholipid syndrome display hippocampal dysfunction and a reduction of dendritic complexity in hippocampal CA1 neurones. Neuropathol Appl Neurobiol. 2015;41:657–71.
    • (2015) Neuropathol Appl Neurobiol , vol.41 , pp. 657-671
    • Frauenknecht, K.1    Katzav, A.2    Weiss Lavi, R.3    Sabag, A.4    Otten, S.5    Chapman, J.6
  • 158
    • 0037392986 scopus 로고    scopus 로고
    • Effects of mothers' autoimmune disease during pregnancy on learning disabilities and hand preference in their children
    • Ross G, Sammaritano L, Nass R, Lockshin M. Effects of mothers' autoimmune disease during pregnancy on learning disabilities and hand preference in their children. Arch Pediatri Adolesc Med. 2003;157(4):397–402.
    • (2003) Arch Pediatri Adolesc Med , vol.157 , Issue.4 , pp. 397-402
    • Ross, G.1    Sammaritano, L.2    Nass, R.3    Lockshin, M.4
  • 159
    • 4644301375 scopus 로고    scopus 로고
    • Neuropsychological development of children born to patients with systemic lupus erythematosus
    • COI: 1:STN:280:DC%2BD2crmvVaisQ%3D%3D
    • Neri F, Chimini L, Bonomi F, Filippini E, Motta M, Faden D, et al. Neuropsychological development of children born to patients with systemic lupus erythematosus. Lupus. 2004;13:805–11.
    • (2004) Lupus , vol.13 , pp. 805-811
    • Neri, F.1    Chimini, L.2    Bonomi, F.3    Filippini, E.4    Motta, M.5    Faden, D.6
  • 160
    • 40849130280 scopus 로고    scopus 로고
    • Neuropsychological development of children born to patients with antiphospholipid syndrome
    • COI: 1:STN:280:DC%2BD1c7pvFyrug%3D%3D
    • Nacinovich R, Galli J, Bomba M, Filippini E, Parrinello G, Nuzzo M, et al. Neuropsychological development of children born to patients with antiphospholipid syndrome. Arthritis Rheum. 2008;59:345–51.
    • (2008) Arthritis Rheum , vol.59 , pp. 345-351
    • Nacinovich, R.1    Galli, J.2    Bomba, M.3    Filippini, E.4    Parrinello, G.5    Nuzzo, M.6
  • 161
    • 78650563353 scopus 로고    scopus 로고
    • Neuropsychiatric aid in children born to patients with rheumatic diseases
    • COI: 1:STN:280:DC%2BC3cbivVChuw%3D%3D
    • Bomba M, Galli J, Nacinovich R, Ceribelli A, Motta M, Lojacono A, et al. Neuropsychiatric aid in children born to patients with rheumatic diseases. Clin Exp Rheumatol. 2010;28:767–73.
    • (2010) Clin Exp Rheumatol , vol.28 , pp. 767-773
    • Bomba, M.1    Galli, J.2    Nacinovich, R.3    Ceribelli, A.4    Motta, M.5    Lojacono, A.6
  • 162
    • 84949198955 scopus 로고    scopus 로고
    • Increased usage of special educational services by children born to mothers with systemic lupus erythematosus and antiphospholipid antibodies
    • Marder W, Romero VC, Ganser MA, Hyzy MA, Gordon C, McCune WJ, et al. Increased usage of special educational services by children born to mothers with systemic lupus erythematosus and antiphospholipid antibodies. Lupus Sci Med. 2014;1:e000034.
    • (2014) Lupus Sci Med , vol.1
    • Marder, W.1    Romero, V.C.2    Ganser, M.A.3    Hyzy, M.A.4    Gordon, C.5    McCune, W.J.6
  • 163
    • 85019967758 scopus 로고    scopus 로고
    • The development of offspring from mothers with systemic lupus erythematosus. A systematic review
    • Yousef Yengej FA, van Royen-Kerkhof A, Derksen R, Fritsch-Stork RDE. The development of offspring from mothers with systemic lupus erythematosus. A systematic review. Autoimmun Rev. 2017;16:701–11.
    • (2017) Autoimmun Rev , vol.16 , pp. 701-711
    • Yousef Yengej, F.A.1    van Royen-Kerkhof, A.2    Derksen, R.3    Fritsch-Stork, R.D.E.4
  • 165
    • 85018283144 scopus 로고    scopus 로고
    • Long-term neurodevelopmental outcome of children born to prospectively followed pregnancies of women with systemic lupus erythematosus and/or antiphospholipid syndrome
    • COI: 1:STN:280:DC%2BC1cvmtlSjtg%3D%3D
    • Nalli C, Iodice A, Andreoli L, Galli J, Lojacono A, Motta M, et al. Long-term neurodevelopmental outcome of children born to prospectively followed pregnancies of women with systemic lupus erythematosus and/or antiphospholipid syndrome. Lupus. 2017;26:552–8.
    • (2017) Lupus , vol.26 , pp. 552-558
    • Nalli, C.1    Iodice, A.2    Andreoli, L.3    Galli, J.4    Lojacono, A.5    Motta, M.6
  • 166
    • 85030620432 scopus 로고    scopus 로고
    • European evidence-based recommendations for diagnosis and treatment of paediatric antiphospholipid syndrome: the SHARE initiative
    • The SHARE initiative was launched to develop diagtic and management regimens for children and young adults with rheumatic diseases. This paper shows the evidence-based recommendations for diagis and treatment of paediatric APS
    • •• Groot N, de Graeff N, Avcin T, Bader-Meunier B, Dolezalova P, Feldman B, et al. European evidence-based recommendations for diagnosis and treatment of paediatric antiphospholipid syndrome: the SHARE initiative. Ann Rheum Dis. 2017;76:1637–41. The SHARE initiative was launched to develop diagnostic and management regimens for children and young adults with rheumatic diseases. This paper shows the evidence-based recommendations for diagnosis and treatment of paediatric APS.
    • (2017) Ann Rheum Dis , vol.76 , pp. 1637-1641
    • Groot, N.1    de Graeff, N.2    Avcin, T.3    Bader-Meunier, B.4    Dolezalova, P.5    Feldman, B.6
  • 167
    • 67649803627 scopus 로고    scopus 로고
    • Epidemiology of the antiphospholipid syndrome
    • Asherson RA, (ed), Elsevier, Amsterdam
    • Mehrania T, Petri M. Epidemiology of the antiphospholipid syndrome. In: Asherson RA, editor. Handbook of systemic autoimmune diseases, vol. 10. Amsterdam: Elsevier; 2009. p. 13–34.
    • (2009) Handbook of systemic autoimmune diseases , vol.10 , pp. 13-34
    • Mehrania, T.1    Petri, M.2
  • 168
    • 84887112232 scopus 로고    scopus 로고
    • The estimated frequency of antiphospholipid antibodies in patients with pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis
    • Andreoli L, Chighizola CB, Banzato A, Pons-Estel GJ, de Jesus GR, Erkan D. The estimated frequency of antiphospholipid antibodies in patients with pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis. Arthritis Care Res (Hoboken). 2013;16:1869–73.
    • (2013) Arthritis Care Res (Hoboken) , vol.16 , pp. 1869-1873
    • Andreoli, L.1    Chighizola, C.B.2    Banzato, A.3    Pons-Estel, G.J.4    de Jesus, G.R.5    Erkan, D.6


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