A novel pathway of cellular activation mediated by antiphospholipid antibody-induced extracellular vesicles

Journal of Thrombosis and Haemostasis

Volumn 13, Issue 10, 2015, Pages 1928-1940

  Wu, M ^a   Barnard, J ^a   Kundu, S ^a   Mccrae, K R ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Antiphospholipid antibodies; Cell derived microparticles; Endothelial cells; Exosomes; Interleukins; Toll like receptors

Indexed keywords

ACETYLSALICYLIC ACID; BETA2 GLYCOPROTEIN 1 ANTIBODY; CLOPIDOGREL; ENOXAPARIN; FONDAPARINUX; IMMUNOGLOBULIN G ANTIBODY; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA ANTIBODY; MICRORNA; MICRORNA 126; PHOSPHOLIPID ANTIBODY; RIBONUCLEASE A; SINGLE STRANDED RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; WARFARIN; BETA2 GLYCOPROTEIN 1; IL1B PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR; TLR7 PROTEIN, HUMAN;

ADULT; ARTICLE; CASE REPORT; CELL ACTIVATION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; EXOSOME; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LUNG EMBOLISM; MALE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; RNA DEGRADATION; RNA INTERFERENCE; UMBILICAL VEIN ENDOTHELIAL CELL; ANTIPHOSPHOLIPID SYNDROME; BLOOD; CELL CULTURE; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; METABOLISM; MIDDLE AGED; SIGNAL TRANSDUCTION;

ANTIBODIES, ANTIPHOSPHOLIPID; ANTIPHOSPHOLIPID SYNDROME; BETA 2-GLYCOPROTEIN I; CELLS, CULTURED; ENDOTHELIAL CELLS; EXTRACELLULAR VESICLES; FEMALE; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MALE; MICRORNAS; MIDDLE AGED; RECEPTORS, INTERLEUKIN-1; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7; TRANSFECTION;

EID: 84942981664     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.13072     Document Type: Article

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