-
1
-
-
33344458573
-
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
-
S. Miyakis, M.D. Lockshin, T. Atsumi, D.W. Branch, R.L. Brey, and R. Cervera International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) J Thromb Haemost 4 2006 295 306
-
(2006)
J Thromb Haemost
, vol.4
, pp. 295-306
-
-
Miyakis, S.1
Lockshin, M.D.2
Atsumi, T.3
Branch, D.W.4
Brey, R.L.5
Cervera, R.6
-
3
-
-
40749116497
-
Interaction of inflammation, thrombosis, aspirin and enoxaparin in CNS experimental antiphospholipid syndrome
-
D. Tanne, A. Katzav, O. Beilin, N.C. Grigoriadis, M. Blank, and C.G. Pick Interaction of inflammation, thrombosis, aspirin and enoxaparin in CNS experimental antiphospholipid syndrome Neurobiol Dis 30 2008 56 64
-
(2008)
Neurobiol Dis
, vol.30
, pp. 56-64
-
-
Tanne, D.1
Katzav, A.2
Beilin, O.3
Grigoriadis, N.C.4
Blank, M.5
Pick, C.G.6
-
4
-
-
70349569565
-
Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies
-
S.V. Seshan, C.W. Franzke, P. Redecha, M. Monestier, N. Mackman, and G. Girardi Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies Blood 114 2009 1675 1683
-
(2009)
Blood
, vol.114
, pp. 1675-1683
-
-
Seshan, S.V.1
Franzke, C.W.2
Redecha, P.3
Monestier, M.4
Mackman, N.5
Girardi, G.6
-
5
-
-
36048993415
-
Tissue factor expression on monocytes induced by anti-phospholipid antibodies as a strong risk factor for thromboembolic complications in SLE patients
-
J. Nojima, Y. Masuda, Y. Iwatani, E. Suehisa, Y. Futsukaichi, and H. Kuratsune Tissue factor expression on monocytes induced by anti-phospholipid antibodies as a strong risk factor for thromboembolic complications in SLE patients Biochem Biophys Res Commun 365 2008 195 200
-
(2008)
Biochem Biophys Res Commun
, vol.365
, pp. 195-200
-
-
Nojima, J.1
Masuda, Y.2
Iwatani, Y.3
Suehisa, E.4
Futsukaichi, Y.5
Kuratsune, H.6
-
6
-
-
67650651969
-
Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway
-
M.J. Mulla, J.J. Brosens, L.W. Chamley, I. Giles, C. Pericleous, and A. Rahman Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway Am J Reprod Immunol 62 2009 96 111
-
(2009)
Am J Reprod Immunol
, vol.62
, pp. 96-111
-
-
Mulla, M.J.1
Brosens, J.J.2
Chamley, L.W.3
Giles, I.4
Pericleous, C.5
Rahman, A.6
-
7
-
-
77951213262
-
Antiphospholipid syndrome: Pathogenesis and a window of treatment opportunities in the future
-
A.A. Mehdi, I. Uthman, and M. Khamashta Antiphospholipid syndrome: pathogenesis and a window of treatment opportunities in the future Eur J Clin Invest 40 2010 451 464
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 451-464
-
-
Mehdi, A.A.1
Uthman, I.2
Khamashta, M.3
-
8
-
-
14944367961
-
Annexin A2 mediates endothelial cell activation by antiphospholipid/anti- beta2 glycoprotein i antibodies
-
J. Zhang, and K.R. McCrae Annexin A2 mediates endothelial cell activation by antiphospholipid/anti-beta2 glycoprotein I antibodies Blood 105 2005 1964 1969
-
(2005)
Blood
, vol.105
, pp. 1964-1969
-
-
Zhang, J.1
McCrae, K.R.2
-
9
-
-
34547914850
-
Involvement of annexin A2 in anti-beta2GPI/beta2GPI-induced tissue factor expression on monocytes
-
H. Zhou, S. Ling, Y. Yu, T. Wang, and H. Hu Involvement of annexin A2 in anti-beta2GPI/beta2GPI-induced tissue factor expression on monocytes Cell Res 17 2007 737 739
-
(2007)
Cell Res
, vol.17
, pp. 737-739
-
-
Zhou, H.1
Ling, S.2
Yu, Y.3
Wang, T.4
Hu, H.5
-
10
-
-
70449509134
-
Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
-
Z. Romay-Penabad, M.G. Montiel-Manzano, T. Shilagard, E. Papalardo, G. Vargas, and A.B. Deora Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo Blood 114 2009 3074 3083
-
(2009)
Blood
, vol.114
, pp. 3074-3083
-
-
Romay-Penabad, Z.1
Montiel-Manzano, M.G.2
Shilagard, T.3
Papalardo, E.4
Vargas, G.5
Deora, A.B.6
-
11
-
-
29144479891
-
Infectious origin of the antiphospholipid syndrome
-
Y. Shoenfeld, M. Blank, R. Cervera, J. Font, E. Raschi, and P.L. Meroni Infectious origin of the antiphospholipid syndrome Ann Rheum Dis 65 2006 2 6
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 2-6
-
-
Shoenfeld, Y.1
Blank, M.2
Cervera, R.3
Font, J.4
Raschi, E.5
Meroni, P.L.6
-
14
-
-
78651270433
-
Deciphering the complexity of Toll-like receptor signaling
-
R. Ostuni, I. Zanoni, and F. Granucci Deciphering the complexity of Toll-like receptor signaling Cell Mol Life Sci 67 2010 4109 4134
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 4109-4134
-
-
Ostuni, R.1
Zanoni, I.2
Granucci, F.3
-
15
-
-
34250721890
-
Toll-like receptor and antiphospholipid mediated thrombosis: In vivo studies
-
S.S. Pierangeli, M.E. Vega-Ostertag, E. Raschi, X. Liu, Z. Romay-Penabad, and V. De Micheli Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies Ann Rheum Dis 66 2007 1327 1333
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 1327-1333
-
-
Pierangeli, S.S.1
Vega-Ostertag, M.E.2
Raschi, E.3
Liu, X.4
Romay-Penabad, Z.5
De Micheli, V.6
-
16
-
-
34547733912
-
Anti-beta2-glycoprotein i antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
-
M. Sorice, A. Longo, A. Capozzi, T. Garofalo, R. Misasi, and C. Alessandri Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts Arthritis Rheum 56 2007 2687 2697
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2687-2697
-
-
Sorice, M.1
Longo, A.2
Capozzi, A.3
Garofalo, T.4
Misasi, R.5
Alessandri, C.6
-
17
-
-
33646494167
-
Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering
-
M. Kobayashi, S. Saitoh, N. Tanimura, K. Takahashi, K. Kawasaki, and M. Nishijima Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering J Immunol 176 2006 6211 6218
-
(2006)
J Immunol
, vol.176
, pp. 6211-6218
-
-
Kobayashi, M.1
Saitoh, S.2
Tanimura, N.3
Takahashi, K.4
Kawasaki, K.5
Nishijima, M.6
-
18
-
-
67649386535
-
Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin
-
N. Resman, J. Vasl, A. Oblak, P. Pristovsek, T.L. Gioannini, and J.P. Weiss Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin J Biol Chem 284 2009 15052 15060
-
(2009)
J Biol Chem
, vol.284
, pp. 15052-15060
-
-
Resman, N.1
Vasl, J.2
Oblak, A.3
Pristovsek, P.4
Gioannini, T.L.5
Weiss, J.P.6
-
19
-
-
68649111238
-
TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in cortex in mice
-
Y. Gao, X. Fang, Y. Tong, Y. Liu, and B. Zhang TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in cortex in mice Biomed Pharmacother 63 2009 442 450
-
(2009)
Biomed Pharmacother
, vol.63
, pp. 442-450
-
-
Gao, Y.1
Fang, X.2
Tong, Y.3
Liu, Y.4
Zhang, B.5
-
20
-
-
77956632266
-
Regulators of TLR4 signaling by endotoxins
-
A.F. McGettrick, and L.A. O'Neill Regulators of TLR4 signaling by endotoxins Subcell Biochem 53 2010 153 171
-
(2010)
Subcell Biochem
, vol.53
, pp. 153-171
-
-
McGettrick, A.F.1
O'Neill, L.A.2
-
21
-
-
3242697048
-
Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep
-
H. Zhou, A.S. Wolberg, and R.A. Roubey Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep Blood 104 2004 2353 2358
-
(2004)
Blood
, vol.104
, pp. 2353-2358
-
-
Zhou, H.1
Wolberg, A.S.2
Roubey, R.A.3
-
22
-
-
70350786142
-
Annexin A2 mediates anti-beta 2 GPI/beta 2 GPI-induced tissue factor expression on monocytes
-
H. Zhou, H. Wang, N. Li, Y. Yu, H. Huang, and Y. Yan Annexin A2 mediates anti-beta 2 GPI/beta 2 GPI-induced tissue factor expression on monocytes Int J Mol Med 24 2009 557 562
-
(2009)
Int J Mol Med
, vol.24
, pp. 557-562
-
-
Zhou, H.1
Wang, H.2
Li, N.3
Yu, Y.4
Huang, H.5
Yan, Y.6
-
23
-
-
78650831137
-
Toll-like receptor (TLR)-4 mediates anti-beta2GPI/beta2GPI-induced tissue factor expression in THP-1 cells
-
H. Zhou, Y. Yan, G. Xu, B. Zhou, H. Wen, and D. Guo Toll-like receptor (TLR)-4 mediates anti-beta2GPI/beta2GPI-induced tissue factor expression in THP-1 cells Clin Exp Immunol 163 2011 189 198
-
(2011)
Clin Exp Immunol
, vol.163
, pp. 189-198
-
-
Zhou, H.1
Yan, Y.2
Xu, G.3
Zhou, B.4
Wen, H.5
Guo, D.6
-
24
-
-
84865959770
-
Anti-beta(2)GPI/beta(2)GPI induced TF and TNF-alpha expression in monocytes involving both TLR4/MyD88 and TLR4/TRIF signaling pathways
-
H. Xie, H. Zhou, H. Wang, D. Chen, L. Xia, and T. Wang Anti-beta(2)GPI/beta(2)GPI induced TF and TNF-alpha expression in monocytes involving both TLR4/MyD88 and TLR4/TRIF signaling pathways Mol Immunol 53 2013 246 254
-
(2013)
Mol Immunol
, vol.53
, pp. 246-254
-
-
Xie, H.1
Zhou, H.2
Wang, H.3
Chen, D.4
Xia, L.5
Wang, T.6
-
25
-
-
77951210466
-
Role of tissue factor in thrombosis in antiphospholipid antibody syndrome
-
J. Boles, and N. Mackman Role of tissue factor in thrombosis in antiphospholipid antibody syndrome Lupus 19 2010 370 378
-
(2010)
Lupus
, vol.19
, pp. 370-378
-
-
Boles, J.1
Mackman, N.2
-
26
-
-
79954444111
-
Increased level of tumor necrosis factor-alpha in patients with antiphospholipid syndrome: Marker not only of inflammation but also of the prothrombotic state
-
J. Swadzba, T. Iwaniec, and J. Musial Increased level of tumor necrosis factor-alpha in patients with antiphospholipid syndrome: marker not only of inflammation but also of the prothrombotic state Rheumatol Int 31 2011 307 313
-
(2011)
Rheumatol Int
, vol.31
, pp. 307-313
-
-
Swadzba, J.1
Iwaniec, T.2
Musial, J.3
-
27
-
-
76749106159
-
Crosstalk between inflammation and thrombosis
-
C.T. Esmon Crosstalk between inflammation and thrombosis Maturitas 61 2008 122 131
-
(2008)
Maturitas
, vol.61
, pp. 122-131
-
-
Esmon, C.T.1
-
28
-
-
0038667615
-
The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover
-
P.K. Wong, I.K. Campbell, P.J. Egan, M. Ernst, and I.P. Wicks The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover Arthritis Rheum 48 2003 1177 1189
-
(2003)
Arthritis Rheum
, vol.48
, pp. 1177-1189
-
-
Wong, P.K.1
Campbell, I.K.2
Egan, P.J.3
Ernst, M.4
Wicks, I.P.5
-
29
-
-
48949119326
-
MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells
-
C. Le Quement, I. Guenon, J.Y. Gillon, V. Lagente, and E. Boichot MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells Am J Physiol Lung Cell Mol Physiol 294 2008 L1076 L1084
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Le Quement, C.1
Guenon, I.2
Gillon, J.Y.3
Lagente, V.4
Boichot, E.5
-
30
-
-
84862909113
-
A novel pathway for human endothelial cell activation by antiphospholipid/anti-beta2 glycoprotein i antibodies
-
K.L. Allen, F.V. Fonseca, V. Betapudi, B. Willard, J. Zhang, and K.R. McCrae A novel pathway for human endothelial cell activation by antiphospholipid/anti-beta2 glycoprotein I antibodies Blood 119 2012 884 893
-
(2012)
Blood
, vol.119
, pp. 884-893
-
-
Allen, K.L.1
Fonseca, F.V.2
Betapudi, V.3
Willard, B.4
Zhang, J.5
McCrae, K.R.6
-
31
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
S. Vallabhapurapu, and M. Karin Regulation and function of NF-kappaB transcription factors in the immune system Annu Rev Immunol 27 2009 693 733
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
32
-
-
84868108264
-
Autoantibodies specific to a peptide of beta2-glycoprotein i cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes
-
T. Colasanti, C. Alessandri, A. Capozzi, M. Sorice, F. Delunardo, and A. Longo Autoantibodies specific to a peptide of beta2-glycoprotein I cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes Blood 120 2012 3360 3370
-
(2012)
Blood
, vol.120
, pp. 3360-3370
-
-
Colasanti, T.1
Alessandri, C.2
Capozzi, A.3
Sorice, M.4
Delunardo, F.5
Longo, A.6
-
33
-
-
77953624768
-
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways
-
A. Lambrianides, C.J. Carroll, S.S. Pierangeli, C. Pericleous, W. Branch, and J. Rice Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways J Immunol 184 2010 6622 6628
-
(2010)
J Immunol
, vol.184
, pp. 6622-6628
-
-
Lambrianides, A.1
Carroll, C.J.2
Pierangeli, S.S.3
Pericleous, C.4
Branch, W.5
Rice, J.6
-
34
-
-
70350304545
-
Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model
-
K. Takashima, N. Matsunaga, M. Yoshimatsu, K. Hazeki, T. Kaisho, and M. Uekata Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model Br J Pharmacol 157 2009 1250 1262
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1250-1262
-
-
Takashima, K.1
Matsunaga, N.2
Yoshimatsu, M.3
Hazeki, K.4
Kaisho, T.5
Uekata, M.6
-
35
-
-
78651300299
-
TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules
-
N. Matsunaga, N. Tsuchimori, T. Matsumoto, and M. Ii TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules Mol Pharmacol 79 2011 34 41
-
(2011)
Mol Pharmacol
, vol.79
, pp. 34-41
-
-
Matsunaga, N.1
Tsuchimori, N.2
Matsumoto, T.3
Ii, M.4
-
36
-
-
77956395908
-
TLR2 is one of the endothelial receptors for beta 2-glycoprotein i
-
J.E. Alard, F. Gaillard, C. Daridon, Y. Shoenfeld, C. Jamin, and P. Youinou TLR2 is one of the endothelial receptors for beta 2-glycoprotein I J Immunol 185 2010 1550 1557
-
(2010)
J Immunol
, vol.185
, pp. 1550-1557
-
-
Alard, J.E.1
Gaillard, F.2
Daridon, C.3
Shoenfeld, Y.4
Jamin, C.5
Youinou, P.6
-
37
-
-
84859420078
-
Examining how antiphospholipid antibodies activate intracellular signaling pathways: A systematic review
-
K. Poulton, A. Rahman, and I. Giles Examining how antiphospholipid antibodies activate intracellular signaling pathways: a systematic review Semin Arthritis Rheum 41 2012 720 736
-
(2012)
Semin Arthritis Rheum
, vol.41
, pp. 720-736
-
-
Poulton, K.1
Rahman, A.2
Giles, I.3
-
38
-
-
79251578627
-
Apolipoprotein e receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome
-
Z. Romay-Penabad, R. Aguilar-Valenzuela, R.T. Urbanus, R.H. Derksen, M.T. Pennings, and E. Papalardo Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome Blood 117 2011 1408 1414
-
(2011)
Blood
, vol.117
, pp. 1408-1414
-
-
Romay-Penabad, Z.1
Aguilar-Valenzuela, R.2
Urbanus, R.T.3
Derksen, R.H.4
Pennings, M.T.5
Papalardo, E.6
-
39
-
-
58849090583
-
Toll-like receptors: Another player in the pathogenesis of the anti-phospholipid syndrome
-
E. Raschi, M.O. Borghi, C. Grossi, V. Broggini, S. Pierangeli, and P.L. Meroni Toll-like receptors: another player in the pathogenesis of the anti-phospholipid syndrome Lupus 17 2008 937 942
-
(2008)
Lupus
, vol.17
, pp. 937-942
-
-
Raschi, E.1
Borghi, M.O.2
Grossi, C.3
Broggini, V.4
Pierangeli, S.5
Meroni, P.L.6
-
40
-
-
77949262403
-
Human antiphospholipid antibodies induce TNFalpha in monocytes via Toll-like receptor 8
-
Y. Doring, J. Hurst, M. Lorenz, N. Prinz, N. Clemens, and M.D. Drechsler Human antiphospholipid antibodies induce TNFalpha in monocytes via Toll-like receptor 8 Immunobiology 215 2010 230 241
-
(2010)
Immunobiology
, vol.215
, pp. 230-241
-
-
Doring, Y.1
Hurst, J.2
Lorenz, M.3
Prinz, N.4
Clemens, N.5
Drechsler, M.D.6
|