Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

Stem Cell Reports

Volumn 5, Issue 1, 2015, Pages 83-96

  Ehrlich, Marc ^a,b   Hallmann, Anna Lena ^a,b   Reinhardt, Peter ^a,c   Araúzo Bravo, Marcos J ^a,d,e   Korr, Sabrina ^b,f   Röpke, Albrecht ^f   Psathaki, Olympia E ^a   Ehling, Petra ^f   Meuth, Sven G ^f   Oblak, Adrian L ^g   Murrell, Jill R ^g   Ghetti, Bernardino ^g   Zaehres, Holm ^a   Schöler, Hans R ^a   Sterneckert, Jared ^a,c   Kuhlmann, Tanja ^b   Hargus, Gunnar ^a,b  

^a MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^d BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^e BASQUE FOUNDATION FOR SCIENCE   (Spain)

^f UNIVERSITY OF MÜNSTER   (Germany)

^g INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; MUTANT PROTEIN; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; STAGE SPECIFIC EMBRYO ANTIGEN 4; TAU PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTOME;

ARTICLE; CONTROLLED STUDY; EVOKED RESPONSE; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; MICROARRAY ANALYSIS; MITOCHONDRIAL RESPIRATION; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NERVE FIBER GROWTH; NEURITE; OXIDATIVE STRESS; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE; BIOSYNTHESIS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MITOCHONDRION; MUTATION; PATHOLOGY;

CELL DIFFERENTIATION; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MITOCHONDRIA; MUTATION; NEURITES; OXIDATIVE STRESS; TAU PROTEINS; UNFOLDED PROTEIN RESPONSE;

EID: 84937526707     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2015.06.001     Document Type: Article

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