-
1
-
-
1842412237
-
Lettre de M. Berzelius à M. Berthollet sur deux métaux nouveaux (Letter from Mr. Berzelius to Mr. Berthollet on two new metals)
-
Berzelius, J.J., Lettre de M. Berzelius à M. Berthollet sur deux métaux nouveaux (Letter from Mr. Berzelius to Mr. Berthollet on two new metals). Ann. Chim. Phys. 7:2 (1818), 199–206.
-
(1818)
Ann. Chim. Phys.
, vol.7
, Issue.2
, pp. 199-206
-
-
Berzelius, J.J.1
-
2
-
-
37549062738
-
Evolutionary dynamics of eukaryotic selenoproteomes: large selenoproteomes may associate with aquatic life and small with terrestrial life
-
Lobanov, A.V., Fomenko, D.E., Zhang, Y., Sengupta, A., Hatfield, D.L., Gladyshev, V.N., Evolutionary dynamics of eukaryotic selenoproteomes: large selenoproteomes may associate with aquatic life and small with terrestrial life. Genome Biol., 8(9), 2007, R198.
-
(2007)
Genome Biol.
, vol.8
, Issue.9
, pp. R198
-
-
Lobanov, A.V.1
Fomenko, D.E.2
Zhang, Y.3
Sengupta, A.4
Hatfield, D.L.5
Gladyshev, V.N.6
-
3
-
-
84966264067
-
Why nature chose selenium
-
Reich, H.J., Hondal, R.J., Why nature chose selenium. ACS Chem. Biol. 11:4 (2016), 821–841.
-
(2016)
ACS Chem. Biol.
, vol.11
, Issue.4
, pp. 821-841
-
-
Reich, H.J.1
Hondal, R.J.2
-
4
-
-
84995535984
-
Why 21? The significance of selenoproteins for human health revealed by inborn errors of metabolism
-
Schweizer, U., Fradejas-Villar, N., Why 21? The significance of selenoproteins for human health revealed by inborn errors of metabolism. FASEB J. 30:11 (2016), 3669–3681.
-
(2016)
FASEB J.
, vol.30
, Issue.11
, pp. 3669-3681
-
-
Schweizer, U.1
Fradejas-Villar, N.2
-
5
-
-
0025743489
-
Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3′ untranslated region
-
Berry, M.J., Banu, L., Chen, Y.Y., Mandel, S.J., Kieffer, J.D., Harney, J.W., Larsen, P.R., Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3′ untranslated region. Nature 353:6341 (1991), 273–276.
-
(1991)
Nature
, vol.353
, Issue.6341
, pp. 273-276
-
-
Berry, M.J.1
Banu, L.2
Chen, Y.Y.3
Mandel, S.J.4
Kieffer, J.D.5
Harney, J.W.6
Larsen, P.R.7
-
6
-
-
0034677213
-
A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs
-
Copeland, P.R., Fletcher, J.E., Carlson, B.A., Hatfield, D.L., Driscoll, D.M., A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs. EMBO J. 19:2 (2000), 306–314.
-
(2000)
EMBO J.
, vol.19
, Issue.2
, pp. 306-314
-
-
Copeland, P.R.1
Fletcher, J.E.2
Carlson, B.A.3
Hatfield, D.L.4
Driscoll, D.M.5
-
7
-
-
0034252526
-
Decoding apparatus for eukaryotic selenocysteine insertion
-
Tujebajeva, R.M., Copeland, P.R., Xu, X.M., Carlson, B.A., Harney, J.W., Driscoll, D.M., Hatfield, D.L., Berry, M.J., Decoding apparatus for eukaryotic selenocysteine insertion. EMBO Rep. 1:2 (2000), 158–163.
-
(2000)
EMBO Rep.
, vol.1
, Issue.2
, pp. 158-163
-
-
Tujebajeva, R.M.1
Copeland, P.R.2
Xu, X.M.3
Carlson, B.A.4
Harney, J.W.5
Driscoll, D.M.6
Hatfield, D.L.7
Berry, M.J.8
-
8
-
-
0024390412
-
Identification of a selenocysteyl-tRNA(Ser) in mammalian cells that recognizes the nonsense codon, UGA
-
Lee, B.J., Worland, P.J., Davis, J.N., Stadtman, T.C., Hatfield, D.L., Identification of a selenocysteyl-tRNA(Ser) in mammalian cells that recognizes the nonsense codon, UGA. J. Biol. Chem. 264:17 (1989), 9724–9727.
-
(1989)
J. Biol. Chem.
, vol.264
, Issue.17
, pp. 9724-9727
-
-
Lee, B.J.1
Worland, P.J.2
Davis, J.N.3
Stadtman, T.C.4
Hatfield, D.L.5
-
9
-
-
0000301355
-
Fetal mouse selenophosphate synthetase 2 (SPS2): characterization of the cysteine mutant form overproduced in a baculovirus-insect cell system
-
Kim, I.Y., Guimaraes, M.J., Zlotnik, A., Bazan, J.F., Stadtman, T.C., Fetal mouse selenophosphate synthetase 2 (SPS2): characterization of the cysteine mutant form overproduced in a baculovirus-insect cell system. Proc. Natl. Acad. Sci. USA 94:2 (1997), 418–421.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, Issue.2
, pp. 418-421
-
-
Kim, I.Y.1
Guimaraes, M.J.2
Zlotnik, A.3
Bazan, J.F.4
Stadtman, T.C.5
-
10
-
-
33846343236
-
Biosynthesis of selenocysteine on its tRNA in eukaryotes
-
Xu, X.M., Carlson, B.A., Mix, H., Zhang, Y., Saira, K., Glass, R.S., Berry, M.J., Gladyshev, V.N., Hatfield, D.L., Biosynthesis of selenocysteine on its tRNA in eukaryotes. PLoS Biol., 5(1), 2007, e4.
-
(2007)
PLoS Biol.
, vol.5
, Issue.1
, pp. e4
-
-
Xu, X.M.1
Carlson, B.A.2
Mix, H.3
Zhang, Y.4
Saira, K.5
Glass, R.S.6
Berry, M.J.7
Gladyshev, V.N.8
Hatfield, D.L.9
-
11
-
-
78650724971
-
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery
-
Xu, X.M., Turanov, A.A., Carlson, B.A., Yoo, M.H., Everley, R.A., Nandakumar, R., Sorokina, I., Gygi, S.P., Gladyshev, V.N., Hatfield, D.L., Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery. Proc. Natl. Acad. Sci. USA 107:50 (2010), 21430–21434.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, Issue.50
, pp. 21430-21434
-
-
Xu, X.M.1
Turanov, A.A.2
Carlson, B.A.3
Yoo, M.H.4
Everley, R.A.5
Nandakumar, R.6
Sorokina, I.7
Gygi, S.P.8
Gladyshev, V.N.9
Hatfield, D.L.10
-
12
-
-
68849087760
-
Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver
-
Lu, J., Zhong, L., Lonn, M.E., Burk, R.F., Hill, K.E., Holmgren, A., Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver. FASEB J. 23:8 (2009), 2394–2402.
-
(2009)
FASEB J.
, vol.23
, Issue.8
, pp. 2394-2402
-
-
Lu, J.1
Zhong, L.2
Lonn, M.E.3
Burk, R.F.4
Hill, K.E.5
Holmgren, A.6
-
13
-
-
33751098548
-
Selenocysteine incorporation machinery and the role of selenoproteins in development and health
-
Hatfield, D.L., Carlson, B.A., Xu, X.M., Mix, H., Gladyshev, V.N., Selenocysteine incorporation machinery and the role of selenoproteins in development and health. Prog. Nucleic Acid. Res. Mol. Biol. 81 (2006), 97–142.
-
(2006)
Prog. Nucleic Acid. Res. Mol. Biol.
, vol.81
, pp. 97-142
-
-
Hatfield, D.L.1
Carlson, B.A.2
Xu, X.M.3
Mix, H.4
Gladyshev, V.N.5
-
14
-
-
34247143425
-
Selenium geochemistry and health
-
Fordyce, F., Selenium geochemistry and health. Ambio 36:1 (2007), 94–97.
-
(2007)
Ambio
, vol.36
, Issue.1
, pp. 94-97
-
-
Fordyce, F.1
-
15
-
-
0000616802
-
Factor 3 activity of selenium compounds
-
Schwarz, K., Foltz, C.M., Factor 3 activity of selenium compounds. J. Biol. Chem. 233:1 (1958), 245–251.
-
(1958)
J. Biol. Chem.
, vol.233
, Issue.1
, pp. 245-251
-
-
Schwarz, K.1
Foltz, C.M.2
-
16
-
-
0015918166
-
Selenium: biochemical role as a component of glutathione peroxidase
-
Rotruck, J.T., Pope, A.L., Ganther, H.E., Swanson, A.B., Hafeman, D.G., Hoekstra, W.G., Selenium: biochemical role as a component of glutathione peroxidase. Science 179:73 (1973), 588–590.
-
(1973)
Science
, vol.179
, Issue.73
, pp. 588-590
-
-
Rotruck, J.T.1
Pope, A.L.2
Ganther, H.E.3
Swanson, A.B.4
Hafeman, D.G.5
Hoekstra, W.G.6
-
17
-
-
0015880169
-
Glutathione peroxidase: a selenoenzyme
-
Flohe, L., Gunzler, W.A., Schock, H.H., Glutathione peroxidase: a selenoenzyme. FEBS Lett. 32:1 (1973), 132–134.
-
(1973)
FEBS Lett.
, vol.32
, Issue.1
, pp. 132-134
-
-
Flohe, L.1
Gunzler, W.A.2
Schock, H.H.3
-
18
-
-
0038442808
-
Characterization of mammalian selenoproteomes
-
Kryukov, G.V., Castellano, S., Novoselov, S.V., Lobanov, A.V., Zehtab, O., Guigo, R., Gladyshev, V.N., Characterization of mammalian selenoproteomes. Science 300:5624 (2003), 1439–1443.
-
(2003)
Science
, vol.300
, Issue.5624
, pp. 1439-1443
-
-
Kryukov, G.V.1
Castellano, S.2
Novoselov, S.V.3
Lobanov, A.V.4
Zehtab, O.5
Guigo, R.6
Gladyshev, V.N.7
-
19
-
-
17944367320
-
Mutations in SEPN1 cause congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome
-
Moghadaszadeh, B., Petit, N., Jaillard, C., Brockington, M., Quijano Roy, S., Merlini, L., Romero, N., Estournet, B., Desguerre, I., Chaigne, D., Muntoni, F., Topaloglu, H., Guicheney, P., Mutations in SEPN1 cause congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Nat. Genet. 29:1 (2001), 17–18.
-
(2001)
Nat. Genet.
, vol.29
, Issue.1
, pp. 17-18
-
-
Moghadaszadeh, B.1
Petit, N.2
Jaillard, C.3
Brockington, M.4
Quijano Roy, S.5
Merlini, L.6
Romero, N.7
Estournet, B.8
Desguerre, I.9
Chaigne, D.10
Muntoni, F.11
Topaloglu, H.12
Guicheney, P.13
-
20
-
-
84995487883
-
Selenoprotein gene nomenclature
-
Gladyshev, V.N., Arner, E.S., Berry, M.J., Brigelius-Flohe, R., Bruford, E.A., Burk, R.F., Carlson, B.A., Castellano, S., Chavatte, L., Conrad, M., Copeland, P.R., Diamond, A.M., Driscoll, D.M., Ferreiro, A., Flohe, L., Green, F.R., Guigo, R., Handy, D.E., Hatfield, D.L., Hesketh, J., Hoffmann, P.R., Holmgren, A., Hondal, R.J., Howard, M.T., Huang, K., Kim, H.Y., Kim, I.Y., Kohrle, J., Krol, A., Kryukov, G.V., Lee, B.J., Lee, B.C., Lei, X.G., Liu, Q., Lescure, A., Lobanov, A.V., Loscalzo, J., Maiorino, M., Mariotti, M., Sandeep Prabhu, K., Rayman, M.P., Rozovsky, S., Salinas, G., Schmidt, E.E., Schomburg, L., Schweizer, U., Simonovic, M., Sunde, R.A., Tsuji, P.A., Tweedie, S., Ursini, F., Whanger, P.D., Zhang, Y., Selenoprotein gene nomenclature. J. Biol. Chem. 291:46 (2016), 24036–24040.
-
(2016)
J. Biol. Chem.
, vol.291
, Issue.46
, pp. 24036-24040
-
-
Gladyshev, V.N.1
Arner, E.S.2
Berry, M.J.3
Brigelius-Flohe, R.4
Bruford, E.A.5
Burk, R.F.6
Carlson, B.A.7
Castellano, S.8
Chavatte, L.9
Conrad, M.10
Copeland, P.R.11
Diamond, A.M.12
Driscoll, D.M.13
Ferreiro, A.14
Flohe, L.15
Green, F.R.16
Guigo, R.17
Handy, D.E.18
Hatfield, D.L.19
Hesketh, J.20
Hoffmann, P.R.21
Holmgren, A.22
Hondal, R.J.23
Howard, M.T.24
Huang, K.25
Kim, H.Y.26
Kim, I.Y.27
Kohrle, J.28
Krol, A.29
Kryukov, G.V.30
Lee, B.J.31
Lee, B.C.32
Lei, X.G.33
Liu, Q.34
Lescure, A.35
Lobanov, A.V.36
Loscalzo, J.37
Maiorino, M.38
Mariotti, M.39
Sandeep Prabhu, K.40
Rayman, M.P.41
Rozovsky, S.42
Salinas, G.43
Schmidt, E.E.44
Schomburg, L.45
Schweizer, U.46
Simonovic, M.47
Sunde, R.A.48
Tsuji, P.A.49
Tweedie, S.50
Ursini, F.51
Whanger, P.D.52
Zhang, Y.53
more..
-
21
-
-
84942790786
-
Membrane-bound selenoproteins
-
Liu, J., Rozovsky, S., Membrane-bound selenoproteins. Antioxid. Redox Signal. 23:10 (2015), 795–813.
-
(2015)
Antioxid. Redox Signal.
, vol.23
, Issue.10
, pp. 795-813
-
-
Liu, J.1
Rozovsky, S.2
-
22
-
-
79961179963
-
Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy
-
Rederstorff, M., Castets, P., Arbogast, S., Laine, J., Vassilopoulos, S., Beuvin, M., Dubourg, O., Vignaud, A., Ferry, A., Krol, A., Allamand, V., Guicheney, P., Ferreiro, A., Lescure, A., Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy. PLoS One, 6(8), 2011, e23094.
-
(2011)
PLoS One
, vol.6
, Issue.8
, pp. e23094
-
-
Rederstorff, M.1
Castets, P.2
Arbogast, S.3
Laine, J.4
Vassilopoulos, S.5
Beuvin, M.6
Dubourg, O.7
Vignaud, A.8
Ferry, A.9
Krol, A.10
Allamand, V.11
Guicheney, P.12
Ferreiro, A.13
Lescure, A.14
-
23
-
-
78649878385
-
Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans
-
Schoenmakers, E., Agostini, M., Mitchell, C., Schoenmakers, N., Papp, L., Rajanayagam, O., Padidela, R., Ceron-Gutierrez, L., Doffinger, R., Prevosto, C., Luan, J., Montano, S., Lu, J., Castanet, M., Clemons, N., Groeneveld, M., Castets, P., Karbaschi, M., Aitken, S., Dixon, A., Williams, J., Campi, I., Blount, M., Burton, H., Muntoni, F., O'Donovan, D., Dean, A., Warren, A., Brierley, C., Baguley, D., Guicheney, P., Fitzgerald, R., Coles, A., Gaston, H., Todd, P., Holmgren, A., Khanna, K.K., Cooke, M., Semple, R., Halsall, D., Wareham, N., Schwabe, J., Grasso, L., Beck-Peccoz, P., Ogunko, A., Dattani, M., Gurnell, M., Chatterjee, K., Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J. Clin. Invest. 120:12 (2010), 4220–4235.
-
(2010)
J. Clin. Invest.
, vol.120
, Issue.12
, pp. 4220-4235
-
-
Schoenmakers, E.1
Agostini, M.2
Mitchell, C.3
Schoenmakers, N.4
Papp, L.5
Rajanayagam, O.6
Padidela, R.7
Ceron-Gutierrez, L.8
Doffinger, R.9
Prevosto, C.10
Luan, J.11
Montano, S.12
Lu, J.13
Castanet, M.14
Clemons, N.15
Groeneveld, M.16
Castets, P.17
Karbaschi, M.18
Aitken, S.19
Dixon, A.20
Williams, J.21
Campi, I.22
Blount, M.23
Burton, H.24
Muntoni, F.25
O'Donovan, D.26
Dean, A.27
Warren, A.28
Brierley, C.29
Baguley, D.30
Guicheney, P.31
Fitzgerald, R.32
Coles, A.33
Gaston, H.34
Todd, P.35
Holmgren, A.36
Khanna, K.K.37
Cooke, M.38
Semple, R.39
Halsall, D.40
Wareham, N.41
Schwabe, J.42
Grasso, L.43
Beck-Peccoz, P.44
Ogunko, A.45
Dattani, M.46
Gurnell, M.47
Chatterjee, K.48
more..
-
24
-
-
70349512259
-
Reactive oxygen species enhance insulin sensitivity
-
Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B.J., Skiba, B., Ooms, L.M., Stepto, N., Wu, B., Mitchell, C.A., Tonks, N.K., Watt, M.J., Febbraio, M.A., Crack, P.J., Andrikopoulos, S., Tiganis, T., Reactive oxygen species enhance insulin sensitivity. Cell Metab. 10:4 (2009), 260–272.
-
(2009)
Cell Metab.
, vol.10
, Issue.4
, pp. 260-272
-
-
Loh, K.1
Deng, H.2
Fukushima, A.3
Cai, X.4
Boivin, B.5
Galic, S.6
Bruce, C.7
Shields, B.J.8
Skiba, B.9
Ooms, L.M.10
Stepto, N.11
Wu, B.12
Mitchell, C.A.13
Tonks, N.K.14
Watt, M.J.15
Febbraio, M.A.16
Crack, P.J.17
Andrikopoulos, S.18
Tiganis, T.19
-
25
-
-
84877584509
-
The syndromes of reduced sensitivity to thyroid hormone
-
Dumitrescu, A.M., Refetoff, S., The syndromes of reduced sensitivity to thyroid hormone. Biochim. Biophys. Acta 1830:7 (2013), 3987–4003.
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, Issue.7
, pp. 3987-4003
-
-
Dumitrescu, A.M.1
Refetoff, S.2
-
26
-
-
84904602887
-
Secisbp2 is essential for embryonic development and enhances selenoprotein expression
-
Seeher, S., Atassi, T., Mahdi, Y., Carlson, B.A., Braun, D., Wirth, E.K., Klein, M.O., Reix, N., Miniard, A.C., Schomburg, L., Hatfield, D.L., Driscoll, D.M., Schweizer, U., Secisbp2 is essential for embryonic development and enhances selenoprotein expression. Antioxid. Redox Signal. 21:6 (2014), 835–849.
-
(2014)
Antioxid. Redox Signal.
, vol.21
, Issue.6
, pp. 835-849
-
-
Seeher, S.1
Atassi, T.2
Mahdi, Y.3
Carlson, B.A.4
Braun, D.5
Wirth, E.K.6
Klein, M.O.7
Reix, N.8
Miniard, A.C.9
Schomburg, L.10
Hatfield, D.L.11
Driscoll, D.M.12
Schweizer, U.13
-
27
-
-
77957731889
-
Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy
-
Agamy, O., Ben Zeev, B., Lev, D., Marcus, B., Fine, D., Su, D., Narkis, G., Ofir, R., Hoffmann, C., Leshinsky-Silver, E., Flusser, H., Sivan, S., Soll, D., Lerman-Sagie, T., Birk, O.S., Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy. Am. J. Hum. Genet. 87:4 (2010), 538–544.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, Issue.4
, pp. 538-544
-
-
Agamy, O.1
Ben Zeev, B.2
Lev, D.3
Marcus, B.4
Fine, D.5
Su, D.6
Narkis, G.7
Ofir, R.8
Hoffmann, C.9
Leshinsky-Silver, E.10
Flusser, H.11
Sivan, S.12
Soll, D.13
Lerman-Sagie, T.14
Birk, O.S.15
-
28
-
-
0142186729
-
Progressive cerebellocerebral atrophy: a new syndrome with microcephaly, mental retardation, and spastic quadriplegia
-
Ben-Zeev, B., Hoffman, C., Lev, D., Watemberg, N., Malinger, G., Brand, N., Lerman-Sagie, T., Progressive cerebellocerebral atrophy: a new syndrome with microcephaly, mental retardation, and spastic quadriplegia. J. Med. Genet., 40(8), 2003, e96.
-
(2003)
J. Med. Genet.
, vol.40
, Issue.8
, pp. e96
-
-
Ben-Zeev, B.1
Hoffman, C.2
Lev, D.3
Watemberg, N.4
Malinger, G.5
Brand, N.6
Lerman-Sagie, T.7
-
29
-
-
84946894024
-
Selenoprotein biosynthesis defect causes progressive encephalopathy with elevated lactate
-
Anttonen, A.K., Hilander, T., Linnankivi, T., Isohanni, P., French, R.L., Liu, Y., Simonovic, M., Soll, D., Somer, M., Muth-Pawlak, D., Corthals, G.L., Laari, A., Ylikallio, E., Lahde, M., Valanne, L., Lonnqvist, T., Pihko, H., Paetau, A., Lehesjoki, A.E., Suomalainen, A., Tyynismaa, H., Selenoprotein biosynthesis defect causes progressive encephalopathy with elevated lactate. Neurology 85:4 (2015), 306–315.
-
(2015)
Neurology
, vol.85
, Issue.4
, pp. 306-315
-
-
Anttonen, A.K.1
Hilander, T.2
Linnankivi, T.3
Isohanni, P.4
French, R.L.5
Liu, Y.6
Simonovic, M.7
Soll, D.8
Somer, M.9
Muth-Pawlak, D.10
Corthals, G.L.11
Laari, A.12
Ylikallio, E.13
Lahde, M.14
Valanne, L.15
Lonnqvist, T.16
Pihko, H.17
Paetau, A.18
Lehesjoki, A.E.19
Suomalainen, A.20
Tyynismaa, H.21
more..
-
30
-
-
84959893617
-
Mutation in human selenocysteine transfer RNA selectively disrupts selenoprotein synthesis
-
Schoenmakers, E., Carlson, B., Agostini, M., Moran, C., Rajanayagam, O., Bochukova, E., Tobe, R., Peat, R., Gevers, E., Muntoni, F., Guicheney, P., Schoenmakers, N., Farooqi, S., Lyons, G., Hatfield, D., Chatterjee, K., Mutation in human selenocysteine transfer RNA selectively disrupts selenoprotein synthesis. J. Clin. Invest. 126:3 (2016), 992–996.
-
(2016)
J. Clin. Invest.
, vol.126
, Issue.3
, pp. 992-996
-
-
Schoenmakers, E.1
Carlson, B.2
Agostini, M.3
Moran, C.4
Rajanayagam, O.5
Bochukova, E.6
Tobe, R.7
Peat, R.8
Gevers, E.9
Muntoni, F.10
Guicheney, P.11
Schoenmakers, N.12
Farooqi, S.13
Lyons, G.14
Hatfield, D.15
Chatterjee, K.16
-
31
-
-
20044378664
-
Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development
-
Jakupoglu, C., Przemeck, G.K., Schneider, M., Moreno, S.G., Mayr, N., Hatzopoulos, A.K., de Angelis, M.H., Wurst, W., Bornkamm, G.W., Brielmeier, M., Conrad, M., Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development. Mol. Cell. Biol. 25:5 (2005), 1980–1988.
-
(2005)
Mol. Cell. Biol.
, vol.25
, Issue.5
, pp. 1980-1988
-
-
Jakupoglu, C.1
Przemeck, G.K.2
Schneider, M.3
Moreno, S.G.4
Mayr, N.5
Hatzopoulos, A.K.6
de Angelis, M.H.7
Wurst, W.8
Bornkamm, G.W.9
Brielmeier, M.10
Conrad, M.11
-
32
-
-
34547766637
-
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome
-
Bondareva, A.A., Capecchi, M.R., Iverson, S.V., Li, Y., Lopez, N.I., Lucas, O., Merrill, G.F., Prigge, J.R., Siders, A.M., Wakamiya, M., Wallin, S.L., Schmidt, E.E., Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic. Biol. Med. 43:6 (2007), 911–923.
-
(2007)
Free Radic. Biol. Med.
, vol.43
, Issue.6
, pp. 911-923
-
-
Bondareva, A.A.1
Capecchi, M.R.2
Iverson, S.V.3
Li, Y.4
Lopez, N.I.5
Lucas, O.6
Merrill, G.F.7
Prigge, J.R.8
Siders, A.M.9
Wakamiya, M.10
Wallin, S.L.11
Schmidt, E.E.12
-
33
-
-
85013765053
-
Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy
-
Kudin, A.P., Baron, G., Zsurka, G., Hampel, K.G., Elger, C.E., Grote, A., Weber, Y., Lerche, H., Thiele, H., Nurnberg, P., Schulz, H., Ruppert, A.K., Sander, T., Cheng, Q., Arner, E.S., Schomburg, L., Seeher, S., Fradejas-Villar, N., Schweizer, U., Kunz, W.S., Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy. Free Radic. Biol. Med. 106 (2017), 270–277.
-
(2017)
Free Radic. Biol. Med.
, vol.106
, pp. 270-277
-
-
Kudin, A.P.1
Baron, G.2
Zsurka, G.3
Hampel, K.G.4
Elger, C.E.5
Grote, A.6
Weber, Y.7
Lerche, H.8
Thiele, H.9
Nurnberg, P.10
Schulz, H.11
Ruppert, A.K.12
Sander, T.13
Cheng, Q.14
Arner, E.S.15
Schomburg, L.16
Seeher, S.17
Fradejas-Villar, N.18
Schweizer, U.19
Kunz, W.S.20
more..
-
34
-
-
79960844507
-
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy
-
Sibbing, D., Pfeufer, A., Perisic, T., Mannes, A.M., Fritz-Wolf, K., Unwin, S., Sinner, M.F., Gieger, C., Gloeckner, C.J., Wichmann, H.E., Kremmer, E., Schafer, Z., Walch, A., Hinterseer, M., Nabauer, M., Kaab, S., Kastrati, A., Schomig, A., Meitinger, T., Bornkamm, G.W., Conrad, M., von Beckerath, N., Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy. Eur. Heart J. 32:9 (2011), 1121–1133.
-
(2011)
Eur. Heart J.
, vol.32
, Issue.9
, pp. 1121-1133
-
-
Sibbing, D.1
Pfeufer, A.2
Perisic, T.3
Mannes, A.M.4
Fritz-Wolf, K.5
Unwin, S.6
Sinner, M.F.7
Gieger, C.8
Gloeckner, C.J.9
Wichmann, H.E.10
Kremmer, E.11
Schafer, Z.12
Walch, A.13
Hinterseer, M.14
Nabauer, M.15
Kaab, S.16
Kastrati, A.17
Schomig, A.18
Meitinger, T.19
Bornkamm, G.W.20
Conrad, M.21
von Beckerath, N.22
more..
-
35
-
-
6344277918
-
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function
-
Conrad, M., Jakupoglu, C., Moreno, S.G., Lippl, S., Banjac, A., Schneider, M., Beck, H., Hatzopoulos, A.K., Just, U., Sinowatz, F., Schmahl, W., Chien, K.R., Wurst, W., Bornkamm, G.W., Brielmeier, M., Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function. Mol. Cell. Biol. 24:21 (2004), 9414–9423.
-
(2004)
Mol. Cell. Biol.
, vol.24
, Issue.21
, pp. 9414-9423
-
-
Conrad, M.1
Jakupoglu, C.2
Moreno, S.G.3
Lippl, S.4
Banjac, A.5
Schneider, M.6
Beck, H.7
Hatzopoulos, A.K.8
Just, U.9
Sinowatz, F.10
Schmahl, W.11
Chien, K.R.12
Wurst, W.13
Bornkamm, G.W.14
Brielmeier, M.15
-
36
-
-
84905819540
-
Thioredoxin reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD)
-
Prasad, R., Chan, L.F., Hughes, C.R., Kaski, J.P., Kowalczyk, J.C., Savage, M.O., Peters, C.J., Nathwani, N., Clark, A.J., Storr, H.L., Metherell, L.A., Thioredoxin reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD). J. Clin. Endocrinol. Metab. 99:8 (2014), E1556–E1563.
-
(2014)
J. Clin. Endocrinol. Metab.
, vol.99
, Issue.8
, pp. E1556-E1563
-
-
Prasad, R.1
Chan, L.F.2
Hughes, C.R.3
Kaski, J.P.4
Kowalczyk, J.C.5
Savage, M.O.6
Peters, C.J.7
Nathwani, N.8
Clark, A.J.9
Storr, H.L.10
Metherell, L.A.11
-
37
-
-
84902545867
-
Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia
-
Smith, A.C., Mears, A.J., Bunker, R., Ahmed, A., MacKenzie, M., Schwartzentruber, J.A., Beaulieu, C.L., Ferretti, E., Consortium, F.C., Majewski, J., Bulman, D.E., Celik, F.C., Boycott, K.M., Graham, G.E., Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia. J. Med. Genet. 51:7 (2014), 470–474.
-
(2014)
J. Med. Genet.
, vol.51
, Issue.7
, pp. 470-474
-
-
Smith, A.C.1
Mears, A.J.2
Bunker, R.3
Ahmed, A.4
MacKenzie, M.5
Schwartzentruber, J.A.6
Beaulieu, C.L.7
Ferretti, E.8
Consortium, F.C.9
Majewski, J.10
Bulman, D.E.11
Celik, F.C.12
Boycott, K.M.13
Graham, G.E.14
-
38
-
-
0037441379
-
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults
-
Yant, L.J., Ran, Q., Rao, L., Van Remmen, H., Shibatani, T., Belter, J.G., Motta, L., Richardson, A., Prolla, T.A., The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults. Free Radic. Biol. Med. 34:4 (2003), 496–502.
-
(2003)
Free Radic. Biol. Med.
, vol.34
, Issue.4
, pp. 496-502
-
-
Yant, L.J.1
Ran, Q.2
Rao, L.3
Van Remmen, H.4
Shibatani, T.5
Belter, J.G.6
Motta, L.7
Richardson, A.8
Prolla, T.A.9
-
39
-
-
0038706048
-
Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene
-
Imai, H., Hirao, F., Sakamoto, T., Sekine, K., Mizukura, Y., Saito, M., Kitamoto, T., Hayasaka, M., Hanaoka, K., Nakagawa, Y., Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene. Biochem. Biophys. Res. Commun. 305:2 (2003), 278–286.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.305
, Issue.2
, pp. 278-286
-
-
Imai, H.1
Hirao, F.2
Sakamoto, T.3
Sekine, K.4
Mizukura, Y.5
Saito, M.6
Kitamoto, T.7
Hayasaka, M.8
Hanaoka, K.9
Nakagawa, Y.10
-
40
-
-
85041924851
-
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis
-
Ingold, I., Berndt, C., Schmitt, S., Doll, S., Poschmann, G., Buday, K., Roveri, A., Peng, X., Porto Freitas, F., Seibt, T., Mehr, L., Aichler, M., Walch, A., Lamp, D., Jastroch, M., Miyamoto, S., Wurst, W., Ursini, F., Arner, E.S.J., Fradejas-Villar, N., Schweizer, U., Zischka, H., Friedmann Angeli, J.P., Conrad, M., Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis. Cell 172:3 (2018), 409–422e21.
-
(2018)
Cell
, vol.172
, Issue.3
, pp. 409-422e21
-
-
Ingold, I.1
Berndt, C.2
Schmitt, S.3
Doll, S.4
Poschmann, G.5
Buday, K.6
Roveri, A.7
Peng, X.8
Porto Freitas, F.9
Seibt, T.10
Mehr, L.11
Aichler, M.12
Walch, A.13
Lamp, D.14
Jastroch, M.15
Miyamoto, S.16
Wurst, W.17
Ursini, F.18
Arner, E.S.J.19
Fradejas-Villar, N.20
Schweizer, U.21
Zischka, H.22
Friedmann Angeli, J.P.23
Conrad, M.24
more..
-
41
-
-
85041931951
-
An element of life
-
Green, D.R., An element of life. Cell 172:3 (2018), 389–390.
-
(2018)
Cell
, vol.172
, Issue.3
, pp. 389-390
-
-
Green, D.R.1
-
42
-
-
84879825604
-
A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities
-
Ronchi, J.A., Figueira, T.R., Ravagnani, F.G., Oliveira, H.C., Vercesi, A.E., Castilho, R.F., A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities. Free Radic. Biol. Med. 63 (2013), 446–456.
-
(2013)
Free Radic. Biol. Med.
, vol.63
, pp. 446-456
-
-
Ronchi, J.A.1
Figueira, T.R.2
Ravagnani, F.G.3
Oliveira, H.C.4
Vercesi, A.E.5
Castilho, R.F.6
-
43
-
-
0030978102
-
Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp)
-
Bosl, M.R., Takaku, K., Oshima, M., Nishimura, S., Taketo, M.M., Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp). Proc. Natl. Acad. Sci. USA 94:11 (1997), 5531–5534.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, Issue.11
, pp. 5531-5534
-
-
Bosl, M.R.1
Takaku, K.2
Oshima, M.3
Nishimura, S.4
Taketo, M.M.5
-
44
-
-
0037372748
-
Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium
-
Kumaraswamy, E., Carlson, B.A., Morgan, F., Miyoshi, K., Robinson, G.W., Su, D., Wang, S., Southon, E., Tessarollo, L., Lee, B.J., Gladyshev, V.N., Hennighausen, L., Hatfield, D.L., Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium. Mol. Cell. Biol. 23:5 (2003), 1477–1488.
-
(2003)
Mol. Cell. Biol.
, vol.23
, Issue.5
, pp. 1477-1488
-
-
Kumaraswamy, E.1
Carlson, B.A.2
Morgan, F.3
Miyoshi, K.4
Robinson, G.W.5
Su, D.6
Wang, S.7
Southon, E.8
Tessarollo, L.9
Lee, B.J.10
Gladyshev, V.N.11
Hennighausen, L.12
Hatfield, D.L.13
-
45
-
-
46249087887
-
A functional link between housekeeping selenoproteins and phase II enzymes
-
Sengupta, A., Carlson, B.A., Weaver, J.A., Novoselov, S.V., Fomenko, D.E., Gladyshev, V.N., Hatfield, D.L., A functional link between housekeeping selenoproteins and phase II enzymes. Biochem. J. 413:1 (2008), 151–161.
-
(2008)
Biochem. J.
, vol.413
, Issue.1
, pp. 151-161
-
-
Sengupta, A.1
Carlson, B.A.2
Weaver, J.A.3
Novoselov, S.V.4
Fomenko, D.E.5
Gladyshev, V.N.6
Hatfield, D.L.7
-
46
-
-
1542289718
-
Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function
-
Carlson, B.A., Novoselov, S.V., Kumaraswamy, E., Lee, B.J., Anver, M.R., Gladyshev, V.N., Hatfield, D.L., Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function. J. Biol. Chem. 279:9 (2004), 8011–8017.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.9
, pp. 8011-8017
-
-
Carlson, B.A.1
Novoselov, S.V.2
Kumaraswamy, E.3
Lee, B.J.4
Anver, M.R.5
Gladyshev, V.N.6
Hatfield, D.L.7
-
47
-
-
84958012664
-
Selenoprotein expression in macrophages is critical for optimal clearance of parasitic helminth Nippostrongylus brasiliensis
-
Nelson, S.M., Shay, A.E., James, J.L., Carlson, B.A., Urban, J.F. Jr., Prabhu, K.S., Selenoprotein expression in macrophages is critical for optimal clearance of parasitic helminth Nippostrongylus brasiliensis. J. Biol. Chem. 291:6 (2016), 2787–2798.
-
(2016)
J. Biol. Chem.
, vol.291
, Issue.6
, pp. 2787-2798
-
-
Nelson, S.M.1
Shay, A.E.2
James, J.L.3
Carlson, B.A.4
Urban, J.F.5
Prabhu, K.S.6
-
48
-
-
84894215578
-
Prostate epithelium-specific deletion of the selenocysteine tRNA gene Trsp leads to early onset intraepithelial neoplasia
-
Luchman, H.A., Villemaire, M.L., Bismar, T.A., Carlson, B.A., Jirik, F.R., Prostate epithelium-specific deletion of the selenocysteine tRNA gene Trsp leads to early onset intraepithelial neoplasia. Am. J. Pathol. 184:3 (2014), 871–877.
-
(2014)
Am. J. Pathol.
, vol.184
, Issue.3
, pp. 871-877
-
-
Luchman, H.A.1
Villemaire, M.L.2
Bismar, T.A.3
Carlson, B.A.4
Jirik, F.R.5
-
49
-
-
38349190048
-
Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2
-
Suzuki, T., Kelly, V.P., Motohashi, H., Nakajima, O., Takahashi, S., Nishimura, S., Yamamoto, M., Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2. J. Biol. Chem. 283:4 (2008), 2021–2030.
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.4
, pp. 2021-2030
-
-
Suzuki, T.1
Kelly, V.P.2
Motohashi, H.3
Nakajima, O.4
Takahashi, S.5
Nishimura, S.6
Yamamoto, M.7
-
50
-
-
78751691722
-
Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia
-
Kawatani, Y., Suzuki, T., Shimizu, R., Kelly, V.P., Yamamoto, M., Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia. Blood 117:3 (2011), 986–996.
-
(2011)
Blood
, vol.117
, Issue.3
, pp. 986-996
-
-
Kawatani, Y.1
Suzuki, T.2
Shimizu, R.3
Kelly, V.P.4
Yamamoto, M.5
-
51
-
-
77649267654
-
Unveiling the molecular mechanisms behind selenium-related diseases through knockout mouse studies
-
Conrad, M., Schweizer, U., Unveiling the molecular mechanisms behind selenium-related diseases through knockout mouse studies. Antioxid. Redox Signal. 12:7 (2010), 851–865.
-
(2010)
Antioxid. Redox Signal.
, vol.12
, Issue.7
, pp. 851-865
-
-
Conrad, M.1
Schweizer, U.2
-
52
-
-
84864311568
-
Understanding selenoprotein function and regulation through the use of rodent models
-
Kasaikina, M.V., Hatfield, D.L., Gladyshev, V.N., Understanding selenoprotein function and regulation through the use of rodent models. Biochim. Biophys. Acta 1823:9 (2012), 1633–1642.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, Issue.9
, pp. 1633-1642
-
-
Kasaikina, M.V.1
Hatfield, D.L.2
Gladyshev, V.N.3
-
53
-
-
85018593400
-
Mouse models that target individual selenoproteins
-
D.L. Hatfield U. Schweizer P.A. Tsuji V.N. Gladyshev Springer International Publishing Cham
-
Conrad, M., Schweizer, U., Mouse models that target individual selenoproteins. Hatfield, D.L., Schweizer, U., Tsuji, P.A., Gladyshev, V.N., (eds.) Selenium: Its Molecular Biology and Role in Human Health, 2016, Springer International Publishing, Cham, 567–578.
-
(2016)
Selenium: Its Molecular Biology and Role in Human Health
, pp. 567-578
-
-
Conrad, M.1
Schweizer, U.2
-
54
-
-
84964804537
-
Selenoprotein T. exerts an essential oxidoreductase activity that protects dopaminergic neurons in mouse models of Parkinson's disease
-
Boukhzar, L., Hamieh, A., Cartier, D., Tanguy, Y., Alsharif, I., Castex, M., Arabo, A., El Hajji, S., Bonnet, J.J., Errami, M., Falluel-Morel, A., Chagraoui, A., Lihrmann, I., Anouar, Y., Selenoprotein T. exerts an essential oxidoreductase activity that protects dopaminergic neurons in mouse models of Parkinson's disease. Antioxid. Redox Signal. 24:11 (2016), 557–574.
-
(2016)
Antioxid. Redox Signal.
, vol.24
, Issue.11
, pp. 557-574
-
-
Boukhzar, L.1
Hamieh, A.2
Cartier, D.3
Tanguy, Y.4
Alsharif, I.5
Castex, M.6
Arabo, A.7
El Hajji, S.8
Bonnet, J.J.9
Errami, M.10
Falluel-Morel, A.11
Chagraoui, A.12
Lihrmann, I.13
Anouar, Y.14
-
55
-
-
85018554656
-
Glutathione peroxidase 4 and ferroptosis
-
D.L. Hatfield U. Schweizer P.A. Tsuji V.N. Gladyshev Springer International Publishing New York
-
Friedmann Angeli, J.P., Proneth, B., Conrad, M., Glutathione peroxidase 4 and ferroptosis. Hatfield, D.L., Schweizer, U., Tsuji, P.A., Gladyshev, V.N., (eds.) Selenium: Its Molecular Biology and Role in Human Health, 2016, Springer International Publishing, New York, 511–521.
-
(2016)
Selenium: Its Molecular Biology and Role in Human Health
, pp. 511-521
-
-
Friedmann Angeli, J.P.1
Proneth, B.2
Conrad, M.3
-
56
-
-
77952294953
-
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration
-
Wirth, E.K., Conrad, M., Winterer, J., Wozny, C., Carlson, B.A., Roth, S., Schmitz, D., Bornkamm, G.W., Coppola, V., Tessarollo, L., Schomburg, L., Kohrle, J., Hatfield, D.L., Schweizer, U., Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration. FASEB J. 24:3 (2010), 844–852.
-
(2010)
FASEB J.
, vol.24
, Issue.3
, pp. 844-852
-
-
Wirth, E.K.1
Conrad, M.2
Winterer, J.3
Wozny, C.4
Carlson, B.A.5
Roth, S.6
Schmitz, D.7
Bornkamm, G.W.8
Coppola, V.9
Tessarollo, L.10
Schomburg, L.11
Kohrle, J.12
Hatfield, D.L.13
Schweizer, U.14
-
57
-
-
84899654597
-
Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons
-
Wirth, E.K., Bharathi, B.S., Hatfield, D., Conrad, M., Brielmeier, M., Schweizer, U., Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons. Biol. Trace Elem. Res. 158:2 (2014), 203–210.
-
(2014)
Biol. Trace Elem. Res.
, vol.158
, Issue.2
, pp. 203-210
-
-
Wirth, E.K.1
Bharathi, B.S.2
Hatfield, D.3
Conrad, M.4
Brielmeier, M.5
Schweizer, U.6
-
58
-
-
84973334339
-
Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration
-
Carlson, B.A., Tobe, R., Yefremova, E., Tsuji, P.A., Hoffmann, V.J., Schweizer, U., Gladyshev, V.N., Hatfield, D.L., Conrad, M., Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration. Redox Biol. 9 (2016), 22–31.
-
(2016)
Redox Biol.
, vol.9
, pp. 22-31
-
-
Carlson, B.A.1
Tobe, R.2
Yefremova, E.3
Tsuji, P.A.4
Hoffmann, V.J.5
Schweizer, U.6
Gladyshev, V.N.7
Hatfield, D.L.8
Conrad, M.9
-
59
-
-
84928238774
-
T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
-
Matsushita, M., Freigang, S., Schneider, C., Conrad, M., Bornkamm, G.W., Kopf, M., T cell lipid peroxidation induces ferroptosis and prevents immunity to infection. J. Exp. Med. 212:4 (2015), 555–568.
-
(2015)
J. Exp. Med.
, vol.212
, Issue.4
, pp. 555-568
-
-
Matsushita, M.1
Freigang, S.2
Schneider, C.3
Conrad, M.4
Bornkamm, G.W.5
Kopf, M.6
-
60
-
-
50649123014
-
Selenoproteins mediate T cell immunity through an antioxidant mechanism
-
Shrimali, R.K., Irons, R.D., Carlson, B.A., Sano, Y., Gladyshev, V.N., Park, J.M., Hatfield, D.L., Selenoproteins mediate T cell immunity through an antioxidant mechanism. J. Biol. Chem. 283:29 (2008), 20181–20185.
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.29
, pp. 20181-20185
-
-
Shrimali, R.K.1
Irons, R.D.2
Carlson, B.A.3
Sano, Y.4
Gladyshev, V.N.5
Park, J.M.6
Hatfield, D.L.7
-
61
-
-
77957892026
-
Selenoproteins are essential for proper keratinocyte function and skin development
-
Sengupta, A., Lichti, U.F., Carlson, B.A., Ryscavage, A.O., Gladyshev, V.N., Yuspa, S.H., Hatfield, D.L., Selenoproteins are essential for proper keratinocyte function and skin development. PLoS One, 5(8), 2010, e12249.
-
(2010)
PLoS One
, vol.5
, Issue.8
, pp. e12249
-
-
Sengupta, A.1
Lichti, U.F.2
Carlson, B.A.3
Ryscavage, A.O.4
Gladyshev, V.N.5
Yuspa, S.H.6
Hatfield, D.L.7
-
62
-
-
84879414710
-
Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2
-
Sengupta, A., Lichti, U.F., Carlson, B.A., Cataisson, C., Ryscavage, A.O., Mikulec, C., Conrad, M., Fischer, S.M., Hatfield, D.L., Yuspa, S.H., Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2. J. Invest. Dermatol. 133:7 (2013), 1731–1741.
-
(2013)
J. Invest. Dermatol.
, vol.133
, Issue.7
, pp. 1731-1741
-
-
Sengupta, A.1
Lichti, U.F.2
Carlson, B.A.3
Cataisson, C.4
Ryscavage, A.O.5
Mikulec, C.6
Conrad, M.7
Fischer, S.M.8
Hatfield, D.L.9
Yuspa, S.H.10
-
63
-
-
84955476379
-
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
-
Canli, O., Alankus, Y.B., Grootjans, S., Vegi, N., Hultner, L., Hoppe, P.S., Schroeder, T., Vandenabeele, P., Bornkamm, G.W., Greten, F.R., Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors. Blood 127:1 (2016), 139–148.
-
(2016)
Blood
, vol.127
, Issue.1
, pp. 139-148
-
-
Canli, O.1
Alankus, Y.B.2
Grootjans, S.3
Vegi, N.4
Hultner, L.5
Hoppe, P.S.6
Schroeder, T.7
Vandenabeele, P.8
Bornkamm, G.W.9
Greten, F.R.10
-
64
-
-
50049133588
-
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death
-
Seiler, A., Schneider, M., Forster, H., Roth, S., Wirth, E.K., Culmsee, C., Plesnila, N., Kremmer, E., Radmark, O., Wurst, W., Bornkamm, G.W., Schweizer, U., Conrad, M., Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death. Cell Metab. 8:3 (2008), 237–248.
-
(2008)
Cell Metab.
, vol.8
, Issue.3
, pp. 237-248
-
-
Seiler, A.1
Schneider, M.2
Forster, H.3
Roth, S.4
Wirth, E.K.5
Culmsee, C.6
Plesnila, N.7
Kremmer, E.8
Radmark, O.9
Wurst, W.10
Bornkamm, G.W.11
Schweizer, U.12
Conrad, M.13
-
65
-
-
84925286831
-
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
-
Friedmann Angeli, J.P., Schneider, M., Proneth, B., Tyurina, Y.Y., Tyurin, V.A., Hammond, V.J., Herbach, N., Aichler, M., Walch, A., Eggenhofer, E., Basavarajappa, D., Radmark, O., Kobayashi, S., Seibt, T., Beck, H., Neff, F., Esposito, I., Wanke, R., Forster, H., Yefremova, O., Heinrichmeyer, M., Bornkamm, G.W., Geissler, E.K., Thomas, S.B., Stockwell, B.R., O'Donnell, V.B., Kagan, V.E., Schick, J.A., Conrad, M., Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat. Cell Biol. 16:12 (2014), 1180–1191.
-
(2014)
Nat. Cell Biol.
, vol.16
, Issue.12
, pp. 1180-1191
-
-
Friedmann Angeli, J.P.1
Schneider, M.2
Proneth, B.3
Tyurina, Y.Y.4
Tyurin, V.A.5
Hammond, V.J.6
Herbach, N.7
Aichler, M.8
Walch, A.9
Eggenhofer, E.10
Basavarajappa, D.11
Radmark, O.12
Kobayashi, S.13
Seibt, T.14
Beck, H.15
Neff, F.16
Esposito, I.17
Wanke, R.18
Forster, H.19
Yefremova, O.20
Heinrichmeyer, M.21
Bornkamm, G.W.22
Geissler, E.K.23
Thomas, S.B.24
Stockwell, B.R.25
O'Donnell, V.B.26
Kagan, V.E.27
Schick, J.A.28
Conrad, M.29
more..
-
66
-
-
84954484374
-
Regulated necrosis: disease relevance and therapeutic opportunities
-
Conrad, M., Angeli, J.P., Vandenabeele, P., Stockwell, B.R., Regulated necrosis: disease relevance and therapeutic opportunities. Nat. Rev. Drug Discov. 15:5 (2016), 348–366.
-
(2016)
Nat. Rev. Drug Discov.
, vol.15
, Issue.5
, pp. 348-366
-
-
Conrad, M.1
Angeli, J.P.2
Vandenabeele, P.3
Stockwell, B.R.4
-
67
-
-
84995468814
-
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
-
Doll, S., Proneth, B., Tyurina, Y.Y., Panzilius, E., Kobayashi, S., Ingold, I., Irmler, M., Beckers, J., Aichler, M., Walch, A., Prokisch, H., Trumbach, D., Mao, G., Qu, F., Bayir, H., Fullekrug, J., Scheel, C.H., Wurst, W., Schick, J.A., Kagan, V.E., Angeli, J.P., Conrad, M., ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat. Chem. Biol. 13:1 (2017), 91–98.
-
(2017)
Nat. Chem. Biol.
, vol.13
, Issue.1
, pp. 91-98
-
-
Doll, S.1
Proneth, B.2
Tyurina, Y.Y.3
Panzilius, E.4
Kobayashi, S.5
Ingold, I.6
Irmler, M.7
Beckers, J.8
Aichler, M.9
Walch, A.10
Prokisch, H.11
Trumbach, D.12
Mao, G.13
Qu, F.14
Bayir, H.15
Fullekrug, J.16
Scheel, C.H.17
Wurst, W.18
Schick, J.A.19
Kagan, V.E.20
Angeli, J.P.21
Conrad, M.22
more..
-
68
-
-
84995452435
-
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
-
Kagan, V.E., Mao, G., Qu, F., Angeli, J.P., Doll, S., Croix, C.S., Dar, H.H., Liu, B., Tyurin, V.A., Ritov, V.B., Kapralov, A.A., Amoscato, A.A., Jiang, J., Anthonymuthu, T., Mohammadyani, D., Yang, Q., Proneth, B., Klein-Seetharaman, J., Watkins, S., Bahar, I., Greenberger, J., Mallampalli, R.K., Stockwell, B.R., Tyurina, Y.Y., Conrad, M., Bayir, H., Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nat. Chem. Biol. 13:1 (2017), 81–90.
-
(2017)
Nat. Chem. Biol.
, vol.13
, Issue.1
, pp. 81-90
-
-
Kagan, V.E.1
Mao, G.2
Qu, F.3
Angeli, J.P.4
Doll, S.5
Croix, C.S.6
Dar, H.H.7
Liu, B.8
Tyurin, V.A.9
Ritov, V.B.10
Kapralov, A.A.11
Amoscato, A.A.12
Jiang, J.13
Anthonymuthu, T.14
Mohammadyani, D.15
Yang, Q.16
Proneth, B.17
Klein-Seetharaman, J.18
Watkins, S.19
Bahar, I.20
Greenberger, J.21
Mallampalli, R.K.22
Stockwell, B.R.23
Tyurina, Y.Y.24
Conrad, M.25
Bayir, H.26
more..
-
69
-
-
85031785818
-
PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals
-
Wenzel, S.E., Tyurina, Y.Y., Zhao, J., St. Croix, C.M., Dar, H.H., Mao, G., Tyurin, V.A., Anthonymuthu, T.S., Kapralov, A.A., Amoscato, A.A., Mikulska-Ruminska, K., Shrivastava, I.H., Kenny, E.M., Yang, Q., Rosenbaum, J.C., Sparvero, L.J., Emlet, D.R., Wen, X., Minami, Y., Qu, F., Watkins, S.C., Holman, T.R., VanDemark, A.P., Kellum, J.A., Bahar, I., Bayir, H., Kagan, V.E., PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals. Cell 171:3 (2017), 628–641 e26.
-
(2017)
Cell
, vol.171
, Issue.3
, pp. 628-641 e26
-
-
Wenzel, S.E.1
Tyurina, Y.Y.2
Zhao, J.3
St. Croix, C.M.4
Dar, H.H.5
Mao, G.6
Tyurin, V.A.7
Anthonymuthu, T.S.8
Kapralov, A.A.9
Amoscato, A.A.10
Mikulska-Ruminska, K.11
Shrivastava, I.H.12
Kenny, E.M.13
Yang, Q.14
Rosenbaum, J.C.15
Sparvero, L.J.16
Emlet, D.R.17
Wen, X.18
Minami, Y.19
Qu, F.20
Watkins, S.C.21
Holman, T.R.22
VanDemark, A.P.23
Kellum, J.A.24
Bahar, I.25
Bayir, H.26
Kagan, V.E.27
more..
-
70
-
-
85041395401
-
Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis
-
Jelinek, A., Heyder, L., Daude, M., Plessner, M., Krippner, S., Grosse, R., Diederich, W.E., Culmsee, C., Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis. Free Radic. Biol. Med. 117 (2018), 45–57.
-
(2018)
Free Radic. Biol. Med.
, vol.117
, pp. 45-57
-
-
Jelinek, A.1
Heyder, L.2
Daude, M.3
Plessner, M.4
Krippner, S.5
Grosse, R.6
Diederich, W.E.7
Culmsee, C.8
-
71
-
-
84983666736
-
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
-
Yang, W.S., Kim, K.J., Gaschler, M.M., Patel, M., Shchepinov, M.S., Stockwell, B.R., Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proc. Natl. Acad. Sci. USA 113:34 (2016), E4966–E4975.
-
(2016)
Proc. Natl. Acad. Sci. USA
, vol.113
, Issue.34
, pp. E4966-E4975
-
-
Yang, W.S.1
Kim, K.J.2
Gaschler, M.M.3
Patel, M.4
Shchepinov, M.S.5
Stockwell, B.R.6
-
72
-
-
3242785011
-
Isoprenoids: remarkable diversity of form and function
-
Holstein, S.A., Hohl, R.J., Isoprenoids: remarkable diversity of form and function. Lipids 39:4 (2004), 293–309.
-
(2004)
Lipids
, vol.39
, Issue.4
, pp. 293-309
-
-
Holstein, S.A.1
Hohl, R.J.2
-
73
-
-
85015695719
-
The modified base isopentenyladenosine and its derivatives in tRNA
-
Schweizer, U., Bohleber, S., Fradejas-Villar, N., The modified base isopentenyladenosine and its derivatives in tRNA. RNA Biol. 14:9 (2017), 1197–1208.
-
(2017)
RNA Biol.
, vol.14
, Issue.9
, pp. 1197-1208
-
-
Schweizer, U.1
Bohleber, S.2
Fradejas-Villar, N.3
-
74
-
-
8144225513
-
Selenoproteins, cholesterol-lowering drugs, and the consequences: revisiting of the mevalonate pathway
-
Moosmann, B., Behl, C., Selenoproteins, cholesterol-lowering drugs, and the consequences: revisiting of the mevalonate pathway. Trends Cardiovasc. Med. 14:7 (2004), 273–281.
-
(2004)
Trends Cardiovasc. Med.
, vol.14
, Issue.7
, pp. 273-281
-
-
Moosmann, B.1
Behl, C.2
-
75
-
-
1642373224
-
Selenoprotein synthesis and side-effects of statins
-
Moosmann, B., Behl, C., Selenoprotein synthesis and side-effects of statins. Lancet 363:9412 (2004), 892–894.
-
(2004)
Lancet
, vol.363
, Issue.9412
, pp. 892-894
-
-
Moosmann, B.1
Behl, C.2
-
76
-
-
84904698842
-
Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network
-
Russo, M.W., Hoofnagle, J.H., Gu, J., Fontana, R.J., Barnhart, H., Kleiner, D.E., Chalasani, N., Bonkovsky, H.L., Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network. Hepatology 60:2 (2014), 679–686.
-
(2014)
Hepatology
, vol.60
, Issue.2
, pp. 679-686
-
-
Russo, M.W.1
Hoofnagle, J.H.2
Gu, J.3
Fontana, R.J.4
Barnhart, H.5
Kleiner, D.E.6
Chalasani, N.7
Bonkovsky, H.L.8
-
77
-
-
84965000436
-
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
-
Shimada, K., Skouta, R., Kaplan, A., Yang, W.S., Hayano, M., Dixon, S.J., Brown, L.M., Valenzuela, C.A., Wolpaw, A.J., Stockwell, B.R., Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat. Chem. Biol. 12:7 (2016), 497–503.
-
(2016)
Nat. Chem. Biol.
, vol.12
, Issue.7
, pp. 497-503
-
-
Shimada, K.1
Skouta, R.2
Kaplan, A.3
Yang, W.S.4
Hayano, M.5
Dixon, S.J.6
Brown, L.M.7
Valenzuela, C.A.8
Wolpaw, A.J.9
Stockwell, B.R.10
-
78
-
-
77958196854
-
Coenzyme Q(10) and statin myalgia: what is the evidence?
-
Mas, E., Mori, T.A., Coenzyme Q(10) and statin myalgia: what is the evidence?. Curr. Atheroscler. Rep. 12:6 (2010), 407–413.
-
(2010)
Curr. Atheroscler. Rep.
, vol.12
, Issue.6
, pp. 407-413
-
-
Mas, E.1
Mori, T.A.2
-
79
-
-
85026414383
-
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
-
(mouse mammary tumor virus)
-
Viswanathan, V.S., Ryan, M.J., Dhruv, H.D., Gill, S., Eichhoff, O.M., Seashore-Ludlow, B., Kaffenberger, S.D., Eaton, J.K., Shimada, K., Aguirre, A.J., Viswanathan, S.R., Chattopadhyay, S., Tamayo, P., Yang, W.S., Rees, M.G., Chen, S., Boskovic, Z.V., Javaid, S., Huang, C., Wu, X., Tseng, Y.Y., Roider, E.M., Gao, D., Cleary, J.M., Wolpin, B.M., Mesirov, J.P., Haber, D.A., Engelman, J.A., Boehm, J.S., Kotz, J.D., Hon, C.S., Chen, Y., Hahn, W.C., Levesque, M.P., Doench, J.G., Berens, M.E., Shamji, A.F., Clemons, P.A., Stockwell, B.R., Schreiber, S.L., Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature 547:7664 (2017), 453–457 (mouse mammary tumor virus).
-
(2017)
Nature
, vol.547
, Issue.7664
, pp. 453-457
-
-
Viswanathan, V.S.1
Ryan, M.J.2
Dhruv, H.D.3
Gill, S.4
Eichhoff, O.M.5
Seashore-Ludlow, B.6
Kaffenberger, S.D.7
Eaton, J.K.8
Shimada, K.9
Aguirre, A.J.10
Viswanathan, S.R.11
Chattopadhyay, S.12
Tamayo, P.13
Yang, W.S.14
Rees, M.G.15
Chen, S.16
Boskovic, Z.V.17
Javaid, S.18
Huang, C.19
Wu, X.20
Tseng, Y.Y.21
Roider, E.M.22
Gao, D.23
Cleary, J.M.24
Wolpin, B.M.25
Mesirov, J.P.26
Haber, D.A.27
Engelman, J.A.28
Boehm, J.S.29
Kotz, J.D.30
Hon, C.S.31
Chen, Y.32
Hahn, W.C.33
Levesque, M.P.34
Doench, J.G.35
Berens, M.E.36
Shamji, A.F.37
Clemons, P.A.38
Stockwell, B.R.39
Schreiber, S.L.40
more..
|