Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

Nature Chemistry

Volumn 9, Issue 11, 2017, Pages 1140-1149

  Könst, Zef A ^a   Szklarski, Anne R ^a   Pellegrino, Simone ^b   Michalak, Sharon E ^a   Meyer, Mélanie ^b   Zanette, Camila ^a   Cencic, Regina ^c   Nam, Sangkil ^d   Voora, Vamsee K ^a   Horne, David A ^d   Pelletier, Jerry ^c   Mobley, David L ^a   Yusupova, Gulnara ^b   Yusupov, Marat ^b   Vanderwal, Christopher D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c MCGILL UNIVERSITY   (Canada)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BIOLOGICAL PRODUCT; CHLOROLISSOCLIMIDE; CYCLOPEPTIDE; DITERPENE; INITIATION FACTOR; LISSOCLINAMIDE 7; LISSOCLINAMIDE 8; SUCCINIMIDE DERIVATIVE;

ANIMAL; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMISTRY; CONFORMATION; DRUG EFFECT; DRUG SCREENING; HUMAN; METABOLISM; MOLECULAR MODEL; MOUSE; PROTEIN SYNTHESIS; SYNTHESIS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; EUKARYOTIC INITIATION FACTORS; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES, CYCLIC; PROTEIN BIOSYNTHESIS; SUCCINIMIDES;

EID: 85042883912     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/NCHEM.2800     Document Type: Article

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