Enantioselective divergent syntheses of several polyhalogenated plocamium monoterpenes and evaluation of their selectivity for solid tumors

Angewandte Chemie - International Edition

Volumn 53, Issue 45, 2014, Pages 12205-12209

  Vogel, Carl V ^a   Pietraszkiewicz, Halina ^b   Sabry, Omar M ^d,e   Gerwick, William H ^c   Valeriote, Frederick A ^b   Vanderwal, Christopher D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HENRY FORD HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d OREGON STATE UNIVERSITY   (United States)

^e CAIRO UNIVERSITY   (Egypt)

Author keywords

antitumor agents; chlorination; olefination; stereocontrol; total synthesis

Indexed keywords

ALGAE; CELL CULTURE; CELLS; CHLORINATION; CYTOLOGY; CYTOTOXICITY; ENANTIOSELECTIVITY; TUMORS;

ANTI-TUMOR AGENTS; DIVERGENT SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; GLYCERALDEHYDE ACETONIDE; OLEFINATION; POLYHALOGENATED MONOTERPENES; STEREOCONTROL; TOTAL SYNTHESIS;

MONOTERPENES;

TERPENE;

CHEMISTRY; HCT116 CELL LINE; HUMAN; NEOPLASMS; PLOCAMIUM; STEREOISOMERISM; SYNTHESIS;

HCT116 CELLS; HUMANS; MONOTERPENES; NEOPLASMS; PLOCAMIUM; STEREOISOMERISM;

EID: 84911463836     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201407726     Document Type: Article

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