Site-Selective Aliphatic C-H Chlorination Using N-Chloroamides Enables a Synthesis of Chlorolissoclimide

Journal of the American Chemical Society

Volumn 138, Issue 2, 2016, Pages 696-702

  Quinn, Ryan K ^a   Könst, Zef A ^b   Michalak, Sharon E ^b   Schmidt, Yvonne ^b   Szklarski, Anne R ^b   Flores, Alex R ^a   Nam, Sangkil ^c   Horne, David A ^c   Vanderwal, Christopher D ^b   Alexanian, Erik J ^a  

^a The University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CHLORINATION; CHLORINE COMPOUNDS; DISEASES; EXCITONS; FREE RADICALS; PARAFFINS;

C-H FUNCTIONALIZATION; FINE CHEMICAL SYNTHESIS; FUNCTIONALIZATIONS; HYDROXYSUCCINIMIDE; INDUSTRIAL PROCESSS; ORGANIC SYNTHESIS; PROSTATE CANCER CELLS; SITE SELECTIVITY;

SYNTHESIS (CHEMICAL);

ALKANE; AMIDE; CHLORIDE; CYCLOHEXANE; HYDROCARBON; CARBON; CHLORINE; CHLOROLISSOCLIMIDE; DITERPENE; HYDROGEN; SUCCINIMIDE DERIVATIVE;

ARTICLE; CHLORINATION; HYDROGEN BOND; IC50; SYNTHESIS;

CARBON; CHLORINE; DITERPENES; HYDROGEN; SUCCINIMIDES;

EID: 84955439482     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b12308     Document Type: Article

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