A fast and straightforward route towards the synthesis of the lissoclimide class of anti-tumour agents

Tetrahedron

Volumn 66, Issue 47, 2010, Pages 9270-9276

  Nguyen, Tuan Minh ^a   Vu, Nguyen Quang ^a   Youte, Jean Jacques ^a   Lau, Jacelyn ^a   Cheong, Angie ^a   San Ho, Ying ^a   Tan, Benjamin S W ^a   Yoganathan, Kanagasundaram ^b   Butler, Mark S ^b   Chai, Christina L L ^a,c  

^a INSTITUTE OF CHEMICAL AND ENGINEERING SCIENCES   (Singapore)

^b MerLion Pharmaceuticals Pte Ltd   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Aldol reaction; Anti Tumour agents; Lissoclimides; Natural products; Terpenoids

Indexed keywords

3 [1 HYDROXY 2 (5,5,8A TRIMETHYL 2 METHYLENEDECAHYDRONAPHTHALEN 1 YL)ETHYL]PYRROLIDINE 2,5 DIONE; ALCOHOL DERIVATIVE; ANTINEOPLASTIC AGENT; BORON; EXOCYCLIC DOUBLE BOND; IMIDE; LISSOCLIMIDE DERIVATIVE; METHANOL; UNCLASSIFIED DRUG;

ALDOL REACTION; AMIDATION; ARTICLE; CHIRALITY; DRUG SYNTHESIS; LACTONIZATION; MICROWAVE RADIATION; PRIORITY JOURNAL;

EID: 78049238949     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.09.031     Document Type: Article

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