Identification of a novel ACE-inhibitory peptide from casein and evaluation of the inhibitory mechanisms

Food Chemistry

Volumn 256, Issue , 2018, Pages 98-104

  Tu, Maolin ^a,c   Wang, Cong ^b   Chen, Cheng ^a   Zhang, Ruyi ^a   Liu, Hanxiong ^a   Lu, Weihong ^c   Jiang, Lianzhou ^b   Du, Ming ^a  

^a DALIAN POLYTECHNIC UNIVERSITY   (China)

^b NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^c HARBIN INSTITUTE OF TECHNOLOGY   (China)

Author keywords

ACE inhibitory activity; Casein peptide; Identification; Molecular docking; UPLC ESI Q TOF MS MS

Indexed keywords

CASEIN; DICHROISM; IDENTIFICATION (CONTROL SYSTEMS); INDUCTIVELY COUPLED PLASMA; MOLECULAR MODELING;

ACE INHIBITORY PEPTIDES; ACE-INHIBITORY ACTIVITY; ANGIOTENSIN I-CONVERTING ENZYME; CASEIN PEPTIDES; LINEWEAVER-BURK PLOTS; MOLECULAR DOCKING; PHYSICOCHEMICAL CHARACTERISTICS; UPLC-ESI-Q-TOF-MS/MS;

PEPTIDES;

CASEIN; CASEIN HYDROLYSATE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PEPTIDE FRAGMENT; POLYPEPTIDE; DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; CIRCULAR DICHROISM; COMPUTER PREDICTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; ELECTROSPRAY MASS SPECTROMETRY; ENZYME DEGRADATION; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC50; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MOLECULAR DOCKING; PHYSICAL CHEMISTRY; PROTEIN SECONDARY STRUCTURE; SOFTWARE; TIME OF FLIGHT MASS SPECTROMETRY; ANIMAL; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CASEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MOLECULAR DOCKING SIMULATION; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; PROTEIN CONFORMATION;

EID: 85042430150     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2018.02.107     Document Type: Article

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