Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice

Cell Death and Differentiation

Volumn 24, Issue 9, 2017, Pages 1598-1608

  Arakawa, Satoko ^a   Tsujioka, Masatsune ^a   Yoshida, Tatsushi ^a   Tajima Sakurai, Hajime ^a   Nishida, Yuya ^a   Matsuoka, Yosuke ^b   Yoshino, Ikuyo ^a   Tsujimoto, Yoshihide ^b   Shimizu, Shigeomi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY RELATED PROTEIN 5; PROTEIN BAK; PROTEIN BAX;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN MALFORMATION; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FIBROBLAST; GENETIC BACKGROUND; IN VIVO STUDY; KNOCKOUT MOUSE; MORPHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; WILD TYPE; ANIMAL; BRAIN; C57BL MOUSE; CELL SURVIVAL; CYTOLOGY; GENETICS; METABOLISM; PHYSIOLOGY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; BRAIN; CELL SURVIVAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 85042207457     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2017.84     Document Type: Article

References (31)

1. Clarke PG. Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol 1990; 181: 195-213.
2. Tsujimoto Y. Cell death regulation by the Bcl-2 protein family in the mitochondria. J Cell Physiol 2003; 195: 158-167.
3. Baehrecke EH. How death shapes life during development. Nat Rev Mol Cell Biol 2002; 3: 779-787.
4. Das G, Shravage BV, Baehrecke EH. Regulation and function of autophagy during cell survival and cell death. Cold Spring Harb Perspect Biol 2012; 4: a008813.
5. Xie Z, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9: 1102-1109.
6. Mizushima N, Yoshimori T, Ohsumi Y. The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol 2011; 27: 107-132.
7. Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T et al. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature 2009; 461: 654-658.
8. Levine B, Yuan J. Autophagy in cell death: an innocent convict? J Clin Invest 2005; 115: 2679-2688.
9. Shen HM, Codogno P. Autophagic cell death: Loch Ness monster or endangered species? Autophagy 2011; 7: 457-465.
10. Denton D, Nicolson S, Kumar S. Cell death by autophagy: facts and apparent artifacts. Cell Death Differ 2012; 19: 87-95.
11. Tracy K, Baehrecke EH. The role of autophagy in Drosophila metamorphosis. Curr Top Dev Biol 2013; 103: 101-125.
12. Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004; 6: 1221-1228.
13. Eisenberg-Lerner A, Bialik S, Simon HU, Kimchi A. Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ 2009; 16: 966-975.
14. Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T et al. The role of autophagy during the early neonatal starvation period. Nature 2004; 432: 1032-1036.
15. Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005; 1: 112-119.
16. Liu Y, Shoji-Kawata S, Sumpter RM Jr, Wei Y, Ginet V, Zhang L et al. Autosis is a Na+, K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. Proc Natl Acad Sci USA 2013; 110: 20364-20371.
17. Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005; 434: 652-658.
18. Zong WX, Ditsworth D, Bauer DE, Wang Z-Q, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004; 18: 1272-1282.
19. Boya P, Kroemer G. Lysosomal membrane permeabilization in cell death. Oncogene 2008; 27: 6434-6451.
20. Kaufmann SH. Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res 1989; 49: 5870-5878.
21. Rathmell JC, Lindsten T, Zong W-X, Cinalli RM, Thompson CB. Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. Nat Immunol 2002; 3: 932-939.
22. Houde C, Banks KG, Coulombe N, Rasper D, Grimm E, Roy S et al. Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase- 3-null mice. J Neurosci 2004; 24: 9977-9984.
23. Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA et al. The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Mol Cell 2000; 6: 1389-1399.
24. Miyanishi M, Tada K, Koike M, Uchiyama Y, Kitamura T, Nagata S. Identification of Tim4 as a phosphatidylserine receptor. Nature 2007; 450: 435-439.
25. Yamaguchi Y, Shinotsuka N, Nonomura K, Takemoto K, Kuida K, Yosida H et al. Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure. J Cell Biol 2011; 195: 1047-1060.
26. Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R et al. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 1998; 94: 739-750.
27. Harris MJ, Juriloff DM. Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects. Birth Defects Res A Clin Mol Teratol 2007; 79: 187-210.
28. Nagasaka A, Kawane K, Yoshida H, Nagata S. Apaf-1-independent programmed cell death in mouse development. Cell Death Differ 2010; 17: 931-941.
29. Newton K, Sun X, Dixit VM. Kinase RIP3 is dispensable for normal NF-κBs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and toll-like receptors 2 and 4. Mol Cell Biol 2004; 24: 1464-1469.
30. Wu J, Huang Z, Ren J, Zhang Z, He P, Li Y et al. Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 2013; 23: 994-1006.
31. Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19: 5720-5728.