Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression

Scientific Reports

Volumn 8, Issue 1, 2018, Pages

  Chaudhary, Kapil ^a   Promsote, Wanwisa ^b   Ananth, Sudha ^c   Veeranan Karmegam, Rajalakshmi ^c   Tawfik, Amany ^d   Arjunan, Pachiappan ^d   Martin, Pamela ^c   Smith, Sylvia B ^c   Thangaraju, Muthusamy ^c   Kisselev, Oleg ^f   Ganapathy, Vadivel ^e   Gnana Prakasam, Jaya P ^f  

^a WASHINGTON UNIVERSITY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d AUGUSTA UNIVERSITY   (United States)

^e TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^f SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GPR91 PROTEIN, MOUSE; IRON; RENIN; STREPTOZOCIN;

ANIMAL; C57BL MOUSE; DIABETIC RETINOPATHY; DISEASE EXACERBATION; DISEASE MODEL; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; IRON OVERLOAD; KNOCKOUT MOUSE; METABOLISM; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOLOGY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RETINA;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; IRON; IRON OVERLOAD; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED; RENIN; RENIN-ANGIOTENSIN SYSTEM; RETINA; STREPTOZOCIN;

EID: 85042114202     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-018-21276-2     Document Type: Article

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