Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 44, 2009, Pages 18728-18733

  Longbottom, Rebecca ^a   Fruttiger, Marcus ^a   Douglas, Ron H ^b   Martinez Barbera, Juan Pedro ^c   Greenwood, John ^a   Moss, Stephen E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CITY UNIVERSITY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cell death; Pigment; Retina

Indexed keywords

CRE RECOMBINASE; DIPHTHERIA TOXIN; MONOCARBOXYLATE TRANSPORTER 3; RHODOPSIN;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL POPULATION; CELL SIZE; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTRORETINOGRAPHY; ENZYME ACTIVITY; GENETIC ANALYSIS; HISTOLOGY; MOUSE; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA; SEQUENCE ANALYSIS; ULTRASTRUCTURE; VISION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELL SHAPE; CELL SURVIVAL; DIPHTHERIA TOXIN; ELECTROPHYSIOLOGICAL PHENOMENA; EPITHELIAL CELLS; GENE DELETION; INTEGRASES; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PHOTORECEPTOR CELLS, VERTEBRATE; RECOMBINATION, GENETIC; RETINAL PIGMENT EPITHELIUM; RHODOPSIN; STRESS, PHYSIOLOGICAL; VISION, OCULAR;

MUS; MUS MUSCULUS;

EID: 73249152430     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902593106     Document Type: Article

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