Increased content of zinc and iron in human cataractous lenses

Biological Trace Element Research

Volumn 90, Issue 1-3, 2002, Pages 15-23

  Dawczynski, J ^a   Blum, M ^b   Winnefeld, K ^c   Strobel, J ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b HELIOS KLINIKUM ERFURT   (Germany)

^c NONE

Author keywords

Atomic absorption spectroscopy; Cataract; Diabetes; Human lenses; Iron; Zinc

Indexed keywords

IRON; ZINC;

ADULT; AGED; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CATARACT; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE;

EID: 12244262242     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1385/BTER:90:1-3:15     Document Type: Article

References (28)

1. C. Kupfer, B. Underwood, and T. Gillen, Leading causes of visual impairment worlwide, in Principles and Practice of Ophthalmology Basic Science (D. M. Albert and F. A. Jakobiec, eds.), W.B. Saunders, Philadelphia (1984).
2. A. J. Bron, J. Sparrow, N. A. P. Brown, J. J. Harding, and R. Blakytny, The lens in diabetes, Eye 7, 260-275 (1993).
3. J. J. Harding, Cataract, Biochemistry, Epidemiology and Pharmacology, Chapman & Hall, London (1991).
4. M. H. Garner and A. Spector, Selective oxidation of cysteine and methioneine in normal and senile cataractous lenses, Proc. Natl. Acad. Sci. USA 77, 1274-1277 (1980).
5. S. Fu, R. T. Dean, M. Southan, and R. J. W. Truscott, The hydroxyl radical in lens nuclear cataractogenesis, J. Biol. Chem. 273, 28,603-28,609 (1998).
6. B. Garner, M. J. Davies, and R. J. W. Truscott, Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract, Exp. Eye Res. 70, 81-88 (2000).
7. D. Garland, Role of site specific, metal-catalyzed oxidation in lens ageing and cataract, Exp. Eye Res. 50, 677-682 (1990).
8. B. Vallee and D. Auld, Zinc coordination, function and structure of zinc enzymes and other proteins, J. Am. Chem. Soc. 29, 5647-5659 (1990).
9. A. S. Prasad, Clinical and biochemical manifestation of zinc deficiency in human subjects, J. Am. Coll. Nutr. 4, 591-598 (1985).
10. B. Garner, K. Roberg, M. Qian, J. W. Eaton, and R. J. W. Truscott, Distribution of ferritin and redox-active transition metals in normal and cataractous human lenses, Exp. Eye Res. 71, 599-607 (2000).
11. G. Duncan and R. Bushell, Ion analysis of human cataractous lenses, Exp. Eye Res. 20, 223-230 (1975).
12. C. D. Eckhert, Elemental concentrations in ocular tissues of various species, Exp. Eye Res. 37, 639-647 (1983).
13. V. K. Srivastava, N. Varshney, and D. C. Padney, Role of trace elements in senile cataract, Acta Ophthalmol. 70, 839-841 (1992).
14. B. Garner, K. Roberg, M. Qian, U. T. Brunk, J. W. Eaton, and R. J. W. Truscott, Redox availability of lens iron and copper implications for hydroxyl radical generation in cataract, Redox Rep. 4, 313-315 (1999).
15. D. J. Rhee and M. F. Pyfer, The Wills Eye Manual, 3rd ed., Lippincott Williams & Wilkins, Philadelphia (1999).
16. T. Nabekura, T. Minami, R. Hirunuma, S. Enomoto, R. Hori, and Y. Ito, Comparative uptake behavior of trace elements in adult and suckling rat lenses, Toxicology 163, 101-105 (2001).
17. O. Cekic, Y. Bardak, Y. Totan, S. Kavakli, O. Akyol, O. Ozdemir, et al., Nickel, chromium, manganese, iron and aluminium levels in human cataractous and normal lenses, Ophthalmic Res. 31, 332-336 (1999).
18. J. S. Fabe, B. H. Grahn, and P. G. Paterson, Zinc concentration of selected ocular tissues in zinc-deficient rats, Biol. Trace Element Res. 75, 43-52 (2000).
19. V. Rasi, S. Costantini, R. Moramarco, R. Giordano, R. Giustolisi, and C. B. Gabrieli, Inorganic element concentrations in cataractous human lenses, Ann. Ophthalmol. 24, 459-464 (1992).
20. V. K. Srivastava, N. Vashney, and D. C. Padney, Role of trace elements in senile cataract, Acta Ophthalmol. 70, 839-841 (1992).
21. V. K. Srivastava, N. Chaturvedi, M. Garg, Z. Maq, and D. C. Padney, Copper and zinc in human senile cataract, Curr. Sci. 57, 1288 (1988).
22. J. H. Kinoshita, Mechanism initiating cataract formation, Invest. Ophthalmol. 13, 713-724 (1974).
23. S. S. Ahmad, K. C. Tsou, S. I. Ahmad, M. A. Rahmann, and T. H. Kirmani, Studies on cataractogenesis in humans and in rats with alloxan-induced diabetes, Ophthalmic Res. 17, 1-11 (1985).
24. G. N. Pierce, N. Afzal, E. A. Kroeger, M. K. Lockwood, M. J. B. Kutryk, C. D. Eckhert, et al., Cataract formation is prevented by administration of verapamil to diabetic rats, Endocrinology 125, 730-735 (1989).
25. O. Cekic and Y. Bardak, Lenticular calcium, magnesium and iron levels in diabetic rats and verapamil effect, Ophthalmic Res. 30, 107-112 (1998).
26. A. S. Duhaiman, N. Rabbani, and E. Cotlier, Camel lens crystallin glycosylation and high molecular weight aggregate formation in the presence of ferrous ions and glucose, Biochem. Biophys. Res. Commun. 173, 823-832 (1990).
27. P. Saxena, A. Saxena, X. Cui, M. Obrenovich, K. Gudipaty, and V. M. Monnier, Transition metal-catalyzed oxidation of ascorbate in human cataract extracts: possible role of advanced glycation end products, Invest. Ophthalmol. Vis. Sci. 41, 1473-1481 (2000).
28. S. Franke, J. Dawczynski, M. Blum, J. Strobel, and G. Stein, Levels of advanced glycation end-products (AGEs) in human cataractous lenses, Exp. Clin. Endocrinol. Diabetes 108, A2-A3 (2000).