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Volumn 2, Issue 10, 2016, Pages

Serine one-carbon catabolism with formate overflow

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELLS; CYTOLOGY; DISEASES; FIBROBLASTS; MAMMALS; METABOLISM;

EID: 85041012891     PISSN: None     EISSN: 23752548     Source Type: Journal    
DOI: 10.1126/sciadv.1601273     Document Type: Article
Times cited : (124)

References (31)
  • 1
    • 77955616558 scopus 로고    scopus 로고
    • Compartmentalization of mammalian folate-mediated onecarbon metabolism
    • A. S. Tibbetts, D. R. Appling, Compartmentalization of mammalian folate-mediated onecarbon metabolism. Annu. Rev. Nutr. 30, 57-81 (2010).
    • (2010) Annu. Rev. Nutr. , vol.30 , pp. 57-81
    • Tibbetts, A.S.1    Appling, D.R.2
  • 2
    • 84881177291 scopus 로고    scopus 로고
    • Serine, glycine and one-carbon units: Cancer metabolism in full circle
    • J. W. Locasale, Serine, glycine and one-carbon units: Cancer metabolism in full circle. Nat. Rev. Cancer 13, 572-583 (2013).
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 572-583
    • Locasale, J.W.1
  • 3
    • 0018137465 scopus 로고
    • Arrest of cell growth in G1 phase of cell cycle by serine deprivation
    • R. W. Allen, M. Moskowitz, Arrest of cell growth in G1 phase of cell cycle by serine deprivation. Exp. Cell Res. 116, 127-137 (1978).
    • (1978) Exp. Cell Res. , vol.116 , pp. 127-137
    • Allen, R.W.1    Moskowitz, M.2
  • 7
  • 8
    • 80355129300 scopus 로고    scopus 로고
    • Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation
    • A. Vazquez, E. K. Markert, Z. N. Oltvai, Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation. PLOS ONE 6, e25881 (2011).
    • (2011) PLOS ONE , vol.6 , pp. e25881
    • Vazquez, A.1    Markert, E.K.2    Oltvai, Z.N.3
  • 9
    • 0027160524 scopus 로고
    • Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine
    • L. F. Garcia-Martinez, D. R. Appling, Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine. Biochemistry 32, 4671-4676 (1993).
    • (1993) Biochemistry , vol.32 , pp. 4671-4676
    • Garcia-Martinez, L.F.1    Appling, D.R.2
  • 11
    • 84955456527 scopus 로고    scopus 로고
    • Division of labour: How does folate metabolism partition between one-carbon metabolism and amino acid oxidation?
    • M. E. Brosnan, L. MacMillan, J. R. Stevens, J. T. Brosnan, Division of labour: How does folate metabolism partition between one-carbon metabolism and amino acid oxidation? Biochem. J. 472, 135-146 (2015).
    • (2015) Biochem. J. , vol.472 , pp. 135-146
    • Brosnan, M.E.1    MacMillan, L.2    Stevens, J.R.3    Brosnan, J.T.4
  • 12
    • 84858782079 scopus 로고    scopus 로고
    • AMPK: A nutrient and energy sensor that maintains energy homeostasis
    • D. G. Hardie, F. A. Ross, S. A. Hawley, AMPK: A nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13, 251-262 (2012).
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 13
    • 0026457218 scopus 로고
    • Nonviability of cells with oxidative defects in galactose medium: A screening test for affected patient fibroblasts
    • B. H. Robinson, R. Petrova-Benedict, J. R. Buncic, D. C. Wallace, Nonviability of cells with oxidative defects in galactose medium: A screening test for affected patient fibroblasts. Biochem. Med. Metab. Biol. 48, 122-126 (1992).
    • (1992) Biochem. Med. Metab. Biol. , vol.48 , pp. 122-126
    • Robinson, B.H.1    Petrova-Benedict, R.2    Buncic, J.R.3    Wallace, D.C.4
  • 15
    • 84964612429 scopus 로고    scopus 로고
    • Give it or take it: The flux of one-carbon in cancer cells
    • J. Meiser, A. Vazquez, Give it or take it: The flux of one-carbon in cancer cells. Febs J., 10.1111/febs.13731 (2016).
    • (2016) Febs J.
    • Meiser, J.1    Vazquez, A.2
  • 16
    • 0025676019 scopus 로고
    • Activity of an NAD-dependent 5, 10-methylenetetrahydrofolate dehydrogenase in normal tissue, neoplastic cells, and oncogene-transformed cells
    • G. K. Smith, S. D. Banks, T. J. Monaco, R. Rigual, D. S. Duch, R. J. Mullin, B. E. Huber, Activity of an NAD-dependent 5, 10-methylenetetrahydrofolate dehydrogenase in normal tissue, neoplastic cells, and oncogene-transformed cells. Arch. Biochem. Biophys. 283, 367-371 (1990).
    • (1990) Arch. Biochem. Biophys. , vol.283 , pp. 367-371
    • Smith, G.K.1    Banks, S.D.2    Monaco, T.J.3    Rigual, R.4    Duch, D.S.5    Mullin, R.J.6    Huber, B.E.7
  • 19
    • 84981329866 scopus 로고    scopus 로고
    • Suppression of MTHFD2 in MCF-7 breast cancer cells increases glycolysis, dependency on exogenous glycine, and sensitivity to folate depletion
    • C. Koufaris, S. Gallage, T. Yang, C. H. Lau, G. N. Valbuena, H. C. Keun, Suppression of MTHFD2 in MCF-7 breast cancer cells increases glycolysis, dependency on exogenous glycine, and sensitivity to folate depletion. J. Proteome Res. 15, 2618-2625 (2016).
    • (2016) J. Proteome Res. , vol.15 , pp. 2618-2625
    • Koufaris, C.1    Gallage, S.2    Yang, T.3    Lau, C.H.4    Valbuena, G.N.5    Keun, H.C.6
  • 20
    • 84890209181 scopus 로고    scopus 로고
    • Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
    • J. Fan, J. J. Kamphorst, R. Mathew, M. K. Chung, E. White, T. Shlomi, J. D. Rabinowitz, Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia. Mol. Syst. Biol. 9, 712 (2013).
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 712
    • Fan, J.1    Kamphorst, J.J.2    Mathew, R.3    Chung, M.K.4    White, E.5    Shlomi, T.6    Rabinowitz, J.D.7
  • 23
    • 84907370814 scopus 로고    scopus 로고
    • Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
    • H. R. Bridges, A. J. Y. Jones, M. N. Pollak, J. Hirst, Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria. Biochem. J. 462, 475-487 (2014).
    • (2014) Biochem. J. , vol.462 , pp. 475-487
    • Bridges, H.R.1    Jones, A.J.Y.2    Pollak, M.N.3    Hirst, J.4
  • 25
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • O. Warburg, On the origin of cancer cells. Science 123, 309-314 (1956).
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 26
    • 77951803596 scopus 로고    scopus 로고
    • Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited
    • A. Vazquez, J. Liu, Y. Zhou, Z. N. Oltvai, Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited. BMC Syst. Biol. 4, 58 (2010).
    • (2010) BMC Syst. Biol. , vol.4 , pp. 58
    • Vazquez, A.1    Liu, J.2    Zhou, Y.3    Oltvai, Z.N.4
  • 28
    • 0035496104 scopus 로고    scopus 로고
    • APC, signal transduction and genetic instability in colorectal cancer
    • R. Fodde, R. Smits, H. Clevers, APC, signal transduction and genetic instability in colorectal cancer. Nat. Rev. Cancer 1, 55-67 (2001).
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 55-67
    • Fodde, R.1    Smits, R.2    Clevers, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.