Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability

Molecular and Cellular Proteomics

Volumn 14, Issue 3, 2015, Pages 621-634

  Patella, Francesca ^a   Schug, Zachary T ^a   Persi, Erez ^b   Neilson, Lisa J ^a   Erami, Zahra ^a   Avanzato, Daniele ^c   Maione, Federica ^c,d   Hernandez Fernaud, Juan R ^a   Mackay, Gillian ^a   Zheng, Liang ^a   Reid, Steven ^a   Frezza, Christian ^e   Giraudo, Enrico ^c,d   Pla, Alessandra Fiorio ^c   Anderson, Kurt ^a   Ruppin, Eytan ^b   Gottlieb, Eyal ^a   Zanivan, Sara ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b TEL AVIV UNIVERSITY   (Israel)

^c UNIVERSITY OF TURIN   (Italy)

^d Candiolo Cancer Institute   (Italy)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ETOMOXIR; OXFENICINE; PLAKOGLOBIN; TYROSINE KINASE RECEPTOR; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A, HUMAN; EPOXIDE; FATTY ACID;

ANGIOGENESIS ASSAY; ARTICLE; BLOOD VESSEL PERMEABILITY; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CELL ADHESION; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL METABOLISM; CELL PROLIFERATION; CITRIC ACID CYCLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENERGY YIELD; FATTY ACID OXIDATION; GLUCOSE INTAKE; GLUCOSE METABOLISM; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRION; MORPHOGENESIS; OSCILLATION; OXIDATION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; REGULATORY MECHANISM; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; CYTOLOGY; IN VITRO STUDY; METABOLISM; METABOLOME; MOUSE; OXIDATION REDUCTION REACTION; PERMEABILITY; PROCEDURES;

ADENOSINE TRIPHOSPHATE; ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; ENDOTHELIAL CELLS; EPOXY COMPOUNDS; FATTY ACIDS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IN VITRO TECHNIQUES; METABOLOME; MICE; MODELS, BIOLOGICAL; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PERMEABILITY; PROTEOMICS;

EID: 84924287407     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M114.045575     Document Type: Article

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