Genetic architecture: The shape of the genetic contribution to human traits and disease

Nature Reviews Genetics

Volumn 19, Issue 2, 2018, Pages 110-124

  Timpson, Nicholas J ^a   Greenwood, Celia M T ^b,c   Soranzo, Nicole ^d,e   Lawson, Daniel J ^a   Richards, J Brent ^b,c,f  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL ASSESSMENT; DECANALIZATION; DRUG DEVELOPMENT; ENVIRONMENTAL IMPACT; GENE INTERACTION; GENE STRUCTURE; GENERAL ASPECTS OF DISEASE; GENETIC ANALYSIS; GENETIC SCREENING; GENETIC TRAIT; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMAN; HUMAN GENETICS; MENDELIAN RANDOMIZATION ANALYSIS; MOLECULAR DIAGNOSIS; NEXT GENERATION SEQUENCING; PHENOTYPIC VARIATION; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; QUANTITATIVE GENETICS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; GENETIC DISORDER; GENETICS; MULTIFACTORIAL INHERITANCE; QUANTITATIVE TRAIT; SINGLE NUCLEOTIDE POLYMORPHISM;

GENETIC DISEASES, INBORN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MULTIFACTORIAL INHERITANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE;

EID: 85040785336     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg.2017.101     Document Type: Review

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