Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants

Nature Communications

Volumn 5, Issue , 2014, Pages

  Panoutsopoulou, Kalliope ^a   Hatzikotoulas, Konstantinos ^a   Xifara, Dionysia Kiara ^b,c   Colonna, Vincenza ^d   Farmaki, Aliki Eleni ^e   Ritchie, Graham R S ^a,f   Southam, Lorraine ^a,b   Gilly, Arthur ^a   Tachmazidou, Ioanna ^a   Fatumo, Segun ^a,g,h   Matchan, Angela ^a   Rayner, Nigel W ^a,b,i   Ntalla, Ioanna ^e,j   Mezzavilla, Massimo ^a,k   Chen, Yuan ^a   Kiagiadaki, Chrysoula ^l   Zengini, Eleni ^m,n   Mamakou, Vasiliki ^m,o   Athanasiadis, Antonis ^p   Giannakopoulou, Margarita ^q   Kariakli, Vassiliki Eirini ^e   Nsubuga, Rebecca N ^r   Karabarinde, Alex ^r   Sandhu, Manjinder ^a,h   McVean, Gil ^b   Tyler Smith, Chris ^a   Tsafantakis, Emmanouil ^l   Karaleftheri, Maria ^p   Xue, Yali ^a   Dedoussis, George ^e   Zeggini, Eleftheria ^a   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^e HAROKOPIO UNIVERSITY   (Greece)

^f EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Italy)

^g Federal Ministry of Science and Technology   (Nigeria)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁱ UNIVERSITY OF OXFORD   (United Kingdom)

^j UNIVERSITY OF LEICESTER   (United Kingdom)

^k UNIVERSITY OF TRIESTE   (Italy)

^l Anogia Medical Centre   (Greece)

^m Psychiatric Hospital of Athens (Dromokaiteio)   (Greece)

ⁿ UNIVERSITY OF SHEFFIELD   (United Kingdom)

^o UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^p Echinos Medical Centre   (Greece)

^q NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^r UGANDA VIRUS RESEARCH INSTITUTE   (Uganda)

more..

Author keywords

[No Author keywords available]

Indexed keywords

GENETIC DRIFT; GENOMICS; PHENOTYPE; SAMPLING; VOLUME;

ARTICLE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DRIFT; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE; GREECE; HAPLOTYPE; HUMAN; INBREEDING DEPRESSION; MAJOR CLINICAL STUDY; MEAN CORPUSCULAR VOLUME; MISSENSE MUTATION; POPULATION GENETICS; RELATIVE DENSITY; ADOLESCENT; BLOOD CELL; CELL SIZE; COHORT ANALYSIS; COMPARATIVE STUDY; CYTOLOGY; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; PHENOTYPE; POPULATION; SOCIAL ISOLATION;

GREECE;

ADOLESCENT; BLOOD CELLS; CELL SIZE; COHORT STUDIES; GENE FREQUENCY; GENETIC DRIFT; GENETIC VARIATION; GENETICS, POPULATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GREECE; HAPLOTYPES; HUMANS; MUTATION, MISSENSE; PHENOTYPE; POPULATION; SOCIAL ISOLATION;

EID: 84923354302     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6345     Document Type: Article

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