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Volumn 1, Issue 14, 2017, Pages 947-960

Novel GM-CSF signals via IFN-gR/IRF-1 and AKT/mTOR license monocytes for suppressor function

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EID: 85040076860     PISSN: 24739529     EISSN: 24739537     Source Type: Journal    
DOI: 10.1182/bloodadvances.2017006858     Document Type: Article
Times cited : (73)

References (56)
  • 2
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009;9(3):162-174.
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 4
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by L-arginine metabolism
    • Bronte V, Zanovello P. Regulation of immune responses by L-arginine metabolism. Nat Rev Immunol. 2005;5(8):641-654.
    • (2005) Nat Rev Immunol , vol.5 , Issue.8 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 5
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. Nitric oxide and the immune response. Nat Immunol. 2001;2(10):907-916.
    • (2001) Nat Immunol , vol.2 , Issue.10 , pp. 907-916
    • Bogdan, C.1
  • 6
    • 70350536358 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell activation by combined LPS and IFN-gamma treatment impairs DC development
    • Greifenberg V, Ribechini E, Rössner S, Lutz MB. Myeloid-derived suppressor cell activation by combined LPS and IFN-gamma treatment impairs DC development. Eur J Immunol. 2009;39(10):2865-2876.
    • (2009) Eur J Immunol , vol.39 , Issue.10 , pp. 2865-2876
    • Greifenberg, V.1    Ribechini, E.2    Rössner, S.3    Lutz, M.B.4
  • 7
    • 33749425534 scopus 로고    scopus 로고
    • Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD81 T cells
    • Gallina G, Dolcetti L, Serafini P, et al. Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD81 T cells. J Clin Invest. 2006;116(10):2777-2790.
    • (2006) J Clin Invest , vol.116 , Issue.10 , pp. 2777-2790
    • Gallina, G.1    Dolcetti, L.2    Serafini, P.3
  • 8
    • 0029957071 scopus 로고    scopus 로고
    • Interferon-gamma confers resistance to experimental allergic encephalomyelitis
    • Krakowski M, Owens T. Interferon-gamma confers resistance to experimental allergic encephalomyelitis. Eur J Immunol. 1996;26(7):1641-1646.
    • (1996) Eur J Immunol , vol.26 , Issue.7 , pp. 1641-1646
    • Krakowski, M.1    Owens, T.2
  • 9
    • 84937572658 scopus 로고    scopus 로고
    • DC-SIGN: The strange case of Dr. Jekyll and Mr. Hyde
    • Garcia-Vallejo JJ, van Kooyk Y. DC-SIGN: the strange case of Dr. Jekyll and Mr. Hyde. Immunity. 2015;42(6):983-985.
    • (2015) Immunity , vol.42 , Issue.6 , pp. 983-985
    • Garcia-Vallejo, J.J.1    van Kooyk, Y.2
  • 10
    • 84862104611 scopus 로고    scopus 로고
    • Defining GM-CSF- And macrophage-CSF-dependent macrophage responses by in vitro models
    • Lacey DC, Achuthan A, Fleetwood AJ, et al. Defining GM-CSF- and macrophage-CSF-dependent macrophage responses by in vitro models. J Immunol. 2012;188(11):5752-5765.
    • (2012) J Immunol , vol.188 , Issue.11 , pp. 5752-5765
    • Lacey, D.C.1    Achuthan, A.2    Fleetwood, A.J.3
  • 11
    • 0025877717 scopus 로고
    • Immunosuppression induced by attenuated Salmonella. Evidence for mediation by macrophage precursors
    • al-Ramadi BK, Brodkin MA, Mosser DM, Eisenstein TK. Immunosuppression induced by attenuated Salmonella. Evidence for mediation by macrophage precursors. J Immunol. 1991;146(8):2737-2746.
    • (1991) J Immunol , vol.146 , Issue.8 , pp. 2737-2746
    • al-Ramadi, B.K.1    Brodkin, M.A.2    Mosser, D.M.3    Eisenstein, T.K.4
  • 12
    • 30044434256 scopus 로고    scopus 로고
    • The mononuclear phagocyte system
    • Hume DA. The mononuclear phagocyte system. Curr Opin Immunol. 2006;18(1):49-53.
    • (2006) Curr Opin Immunol , vol.18 , Issue.1 , pp. 49-53
    • Hume, D.A.1
  • 13
    • 29744454134 scopus 로고    scopus 로고
    • Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro
    • Rössner S, Voigtländer C, Wiethe C, Hänig J, Seifarth C, Lutz MB. Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro. Eur J Immunol. 2005;35(12):3533-3544.
    • (2005) Eur J Immunol , vol.35 , Issue.12 , pp. 3533-3544
    • Rössner, S.1    Voigtländer, C.2    Wiethe, C.3    Hänig, J.4    Seifarth, C.5    Lutz, M.B.6
  • 14
    • 0033562982 scopus 로고    scopus 로고
    • Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD81 T cell responses by dysregulating antigen-presenting cell maturation
    • Bronte V, Chappell DB, Apolloni E, et al. Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD81 T cell responses by dysregulating antigen-presenting cell maturation. J Immunol. 1999;162(10):5728-5737.
    • (1999) J Immunol , vol.162 , Issue.10 , pp. 5728-5737
    • Bronte, V.1    Chappell, D.B.2    Apolloni, E.3
  • 15
    • 48449102092 scopus 로고    scopus 로고
    • The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation
    • Hansen G, Hercus TR, McClure BJ, et al. The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell. 2008;134(3):496-507.
    • (2008) Cell , vol.134 , Issue.3 , pp. 496-507
    • Hansen, G.1    Hercus, T.R.2    McClure, B.J.3
  • 16
    • 33749611445 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells
    • Lee AW, States DJ. Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells. Cell Death Differ. 2006;13(11):1900-1914.
    • (2006) Cell Death Differ , vol.13 , Issue.11 , pp. 1900-1914
    • Lee, A.W.1    States, D.J.2
  • 17
    • 84857618521 scopus 로고    scopus 로고
    • Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling
    • Hume DA, MacDonald KP. Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling. Blood. 2012;119(8):1810-1820.
    • (2012) Blood , vol.119 , Issue.8 , pp. 1810-1820
    • Hume, D.A.1    MacDonald, K.P.2
  • 18
    • 84996523368 scopus 로고    scopus 로고
    • PI3Kg is a molecular switch that controls immune suppression
    • Kaneda MM, Messer KS, Ralainirina N, et al. PI3Kg is a molecular switch that controls immune suppression. Nature. 2016;539(7629):437-442.
    • (2016) Nature , vol.539 , Issue.7629 , pp. 437-442
    • Kaneda, M.M.1    Messer, K.S.2    Ralainirina, N.3
  • 19
    • 84956606229 scopus 로고    scopus 로고
    • MTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors
    • Wu T, Zhao Y, Wang H, et al. mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors. Sci Rep. 2016;6:20250.
    • (2016) Sci Rep , vol.6 , pp. 20250
    • Wu, T.1    Zhao, Y.2    Wang, H.3
  • 21
    • 29744454134 scopus 로고    scopus 로고
    • Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro
    • Rössner S, Voigtländer C, Wiethe C, Hänig J, Seifarth C, Lutz MB. Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro. Eur J Immunol. 2005;35(12):3533-3544.
    • (2005) Eur J Immunol , vol.35 , Issue.12 , pp. 3533-3544
    • Rössner, S.1    Voigtländer, C.2    Wiethe, C.3    Hänig, J.4    Seifarth, C.5    Lutz, M.B.6
  • 22
    • 0031048823 scopus 로고    scopus 로고
    • Reduced incidence and severity of antigen-induced autoimmune diseases in mice lacking interferon regulatory factor-1
    • Tada Y, Ho A, Matsuyama T, Mak TW. Reduced incidence and severity of antigen-induced autoimmune diseases in mice lacking interferon regulatory factor-1. J Exp Med. 1997;185(2):231-238.
    • (1997) J Exp Med , vol.185 , Issue.2 , pp. 231-238
    • Tada, Y.1    Ho, A.2    Matsuyama, T.3    Mak, T.W.4
  • 23
    • 0027464928 scopus 로고
    • Immune response in mice that lack the interferon-gamma receptor
    • Huang S, Hendriks W, Althage A, et al. Immune response in mice that lack the interferon-gamma receptor. Science. 1993;259(5102):1742-1745.
    • (1993) Science , vol.259 , Issue.5102 , pp. 1742-1745
    • Huang, S.1    Hendriks, W.2    Althage, A.3
  • 24
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
    • Dalton DK, Pitts-Meek S, Keshav S, Figari IS, Bradley A, Stewart TA. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science. 1993;259(5102):1739-1742.
    • (1993) Science , vol.259 , Issue.5102 , pp. 1739-1742
    • Dalton, D.K.1    Pitts-Meek, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 25
    • 84999779395 scopus 로고    scopus 로고
    • GM-CSF: From growth factor to central mediator of tissue inflammation
    • Becher B, Tugues S, Greter M. GM-CSF: from growth factor to central mediator of tissue inflammation. Immunity. 2016;45(5):963-973.
    • (2016) Immunity , vol.45 , Issue.5 , pp. 963-973
    • Becher, B.1    Tugues, S.2    Greter, M.3
  • 26
    • 80052650727 scopus 로고    scopus 로고
    • Cutting edge: Immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients
    • Hutchinson JA, Riquelme P, Sawitzki B, et al. Cutting edge: immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients. J Immunol. 2011;187(5):2072-2078.
    • (2011) J Immunol , vol.187 , Issue.5 , pp. 2072-2078
    • Hutchinson, J.A.1    Riquelme, P.2    Sawitzki, B.3
  • 27
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29(9):e45.
    • (2001) Nucleic Acids Res , vol.29 , Issue.9 , pp. e45
    • Pfaffl, M.W.1
  • 29
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    • Menges M, Rössner S, Voigtländer C, et al. Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med. 2002;195(1):15-21.
    • (2002) J Exp Med , vol.195 , Issue.1 , pp. 15-21
    • Menges, M.1    Rössner, S.2    Voigtländer, C.3
  • 30
    • 46249090513 scopus 로고    scopus 로고
    • Colony-stimulating factors in inflammation and autoimmunity
    • Hamilton JA. Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol. 2008;8(7):533-544.
    • (2008) Nat Rev Immunol , vol.8 , Issue.7 , pp. 533-544
    • Hamilton, J.A.1
  • 31
    • 74249101123 scopus 로고    scopus 로고
    • Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF
    • Dolcetti L, Peranzoni E, Ugel S, et al. Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF. Eur J Immunol. 2010;40(1):22-35.
    • (2010) Eur J Immunol , vol.40 , Issue.1 , pp. 22-35
    • Dolcetti, L.1    Peranzoni, E.2    Ugel, S.3
  • 32
    • 43249130187 scopus 로고    scopus 로고
    • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
    • Movahedi K, Guilliams M, Van den Bossche J, et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood. 2008;111(8):4233-4244.
    • (2008) Blood , vol.111 , Issue.8 , pp. 4233-4244
    • Movahedi, K.1    Guilliams, M.2    van den Bossche, J.3
  • 33
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol. 2008;181(8):5791-5802.
    • (2008) J Immunol , vol.181 , Issue.8 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 34
    • 70349336496 scopus 로고    scopus 로고
    • The granulocyte-macrophage colony-stimulating factor receptor: Linking its structure to cell signaling and its role in disease
    • Hercus TR, Thomas D, Guthridge MA, et al. The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease. Blood. 2009;114(7):1289-1298.
    • (2009) Blood , vol.114 , Issue.7 , pp. 1289-1298
    • Hercus, T.R.1    Thomas, D.2    Guthridge, M.A.3
  • 35
    • 77958185103 scopus 로고    scopus 로고
    • Nomenclature of monocytes and dendritic cells in blood
    • Ziegler-Heitbrock L, Ancuta P, Crowe S, et al. Nomenclature of monocytes and dendritic cells in blood. Blood. 2010;116(16):e74-e80.
    • (2010) Blood , vol.116 , Issue.16 , pp. e74-e80
    • Ziegler-Heitbrock, L.1    Ancuta, P.2    Crowe, S.3
  • 36
    • 77950516104 scopus 로고    scopus 로고
    • MTOR signaling and drug development in cancer
    • Dancey J. mTOR signaling and drug development in cancer. Nat Rev Clin Oncol. 2010;7(4):209-219.
    • (2010) Nat Rev Clin Oncol , vol.7 , Issue.4 , pp. 209-219
    • Dancey, J.1
  • 37
    • 53349099219 scopus 로고    scopus 로고
    • Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
    • Cheng P, Corzo CA, Luetteke N, et al. Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J Exp Med. 2008;205(10):2235-2249.
    • (2008) J Exp Med , vol.205 , Issue.10 , pp. 2235-2249
    • Cheng, P.1    Corzo, C.A.2    Luetteke, N.3
  • 38
    • 80053224991 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis
    • Wu L, Du H, Li Y, Qu P, Yan C. Signal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis. Am J Pathol. 2011;179(4):2131-2141.
    • (2011) Am J Pathol , vol.179 , Issue.4 , pp. 2131-2141
    • Wu, L.1    Du, H.2    Li, Y.3    Qu, P.4    Yan, C.5
  • 39
    • 79952200691 scopus 로고    scopus 로고
    • Regulation of lymphocytes by nitric oxide
    • Bogdan C. Regulation of lymphocytes by nitric oxide. Methods Mol Biol. 2011;677:375-393.
    • (2011) Methods Mol Biol , vol.677 , pp. 375-393
    • Bogdan, C.1
  • 40
    • 0028348307 scopus 로고
    • Requirement for transcription factor IRF-1 in NO synthase induction in macrophages
    • Kamijo R, Harada H, Matsuyama T, et al. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science. 1994; 263(5153):1612-1615.
    • (1994) Science , vol.263 , Issue.5153 , pp. 1612-1615
    • Kamijo, R.1    Harada, H.2    Matsuyama, T.3
  • 41
    • 0028106830 scopus 로고
    • Role of interferon regulatory factor 1 in induction of nitric oxide synthase
    • Martin E, Nathan C, Xie QW. Role of interferon regulatory factor 1 in induction of nitric oxide synthase. J Exp Med. 1994;180(3):977-984.
    • (1994) J Exp Med , vol.180 , Issue.3 , pp. 977-984
    • Martin, E.1    Nathan, C.2    Xie, Q.W.3
  • 42
    • 33750064259 scopus 로고    scopus 로고
    • Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program
    • Negishi H, Fujita Y, Yanai H, et al. Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program. Proc Natl Acad Sci USA. 2006;103(41):15136-15141.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.41 , pp. 15136-15141
    • Negishi, H.1    Fujita, Y.2    Yanai, H.3
  • 44
    • 79956116032 scopus 로고    scopus 로고
    • RORgt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
    • Codarri L, Gyülvészi G, Tosevski V, et al. RORgt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat Immunol. 2011;12(6):560-567.
    • (2011) Nat Immunol , vol.12 , Issue.6 , pp. 560-567
    • Codarri, L.1    Gyülvészi, G.2    Tosevski, V.3
  • 45
    • 79956152607 scopus 로고    scopus 로고
    • The encephalitogenicity of T(H)17 cells is dependent on IL-1- And IL-23-induced production of the cytokine GM-CSF
    • El-Behi M, Ciric B, Dai H, et al. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat Immunol. 2011;12(6):568-575.
    • (2011) Nat Immunol , vol.12 , Issue.6 , pp. 568-575
    • El-Behi, M.1    Ciric, B.2    Dai, H.3
  • 46
    • 33847258205 scopus 로고    scopus 로고
    • Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
    • Parmiani G, Castelli C, Pilla L, Santinami M, Colombo MP, Rivoltini L. Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann Oncol. 2007;18(2):226-232.
    • (2007) Ann Oncol , vol.18 , Issue.2 , pp. 226-232
    • Parmiani, G.1    Castelli, C.2    Pilla, L.3    Santinami, M.4    Colombo, M.P.5    Rivoltini, L.6
  • 47
    • 0028247216 scopus 로고
    • Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis
    • Lechner AJ, Lamprech KE, Potthoff LH, Tredway TL, Matuschak GM. Recombinant GM-CSF reduces lung injury and mortality during neutropenic Candida sepsis. Am J Physiol. 1994;266(5 Pt 1):L561-L568.
    • (1994) Am J Physiol , vol.266 , Issue.5 , pp. L561-L568
    • Lechner, A.J.1    Lamprech, K.E.2    Potthoff, L.H.3    Tredway, T.L.4    Matuschak, G.M.5
  • 48
    • 84941735780 scopus 로고    scopus 로고
    • The cytokine GM-CSF drives the inflammatory signature of CCR21 monocytes and licenses autoimmunity
    • Croxford AL, Lanzinger M, Hartmann FJ, et al. The cytokine GM-CSF drives the inflammatory signature of CCR21 monocytes and licenses autoimmunity. Immunity. 2015;43(3):502-514.
    • (2015) Immunity , vol.43 , Issue.3 , pp. 502-514
    • Croxford, A.L.1    Lanzinger, M.2    Hartmann, F.J.3
  • 49
    • 85028452339 scopus 로고    scopus 로고
    • GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro
    • Gargett T, Christo SN, Hercus TR, et al. GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro. Clin Transl Immunology. 2016;5(12):e119.
    • (2016) Clin Transl Immunology , vol.5 , Issue.12 , pp. e119
    • Gargett, T.1    Christo, S.N.2    Hercus, T.R.3
  • 50
    • 84885696103 scopus 로고    scopus 로고
    • Tumor-induced myeloid-derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD81 T-cell activation events
    • Schouppe E, Mommer C, Movahedi K, et al. Tumor-induced myeloid-derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD81 T-cell activation events. Eur J Immunol. 2013;43(11):2930-2942.
    • (2013) Eur J Immunol , vol.43 , Issue.11 , pp. 2930-2942
    • Schouppe, E.1    Mommer, C.2    Movahedi, K.3
  • 51
    • 0035061538 scopus 로고    scopus 로고
    • IRF family of transcription factors as regulators of host defense
    • Taniguchi T, Ogasawara K, Takaoka A, Tanaka N. IRF family of transcription factors as regulators of host defense. Annu Rev Immunol. 2001;19:623-655.
    • (2001) Annu Rev Immunol , vol.19 , pp. 623-655
    • Taniguchi, T.1    Ogasawara, K.2    Takaoka, A.3    Tanaka, N.4
  • 52
    • 4644275692 scopus 로고    scopus 로고
    • Characterization of a dipeptide motif regulating IFN-gamma receptor 2 plasma membrane accumulation and IFN-gamma responsiveness
    • Rosenzweig SD, Schwartz OM, Brown MR, Leto TL, Holland SM. Characterization of a dipeptide motif regulating IFN-gamma receptor 2 plasma membrane accumulation and IFN-gamma responsiveness. J Immunol. 2004;173(6):3991-3999.
    • (2004) J Immunol , vol.173 , Issue.6 , pp. 3991-3999
    • Rosenzweig, S.D.1    Schwartz, O.M.2    Brown, M.R.3    Leto, T.L.4    Holland, S.M.5
  • 54
    • 84924228289 scopus 로고    scopus 로고
    • Nitric oxide synthase in innate and adaptive immunity: An update
    • Bogdan C. Nitric oxide synthase in innate and adaptive immunity: an update. Trends Immunol. 2015;36(3):161-178.
    • (2015) Trends Immunol , vol.36 , Issue.3 , pp. 161-178
    • Bogdan, C.1
  • 55
    • 34249003035 scopus 로고    scopus 로고
    • Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase
    • Keskin DB, Marshall B, Munn D, Mellor AL, Gearhart DA. Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase. Cell Mol Biol Lett. 2007;12(1):82-102.
    • (2007) Cell Mol Biol Lett , vol.12 , Issue.1 , pp. 82-102
    • Keskin, D.B.1    Marshall, B.2    Munn, D.3    Mellor, A.L.4    Gearhart, D.A.5
  • 56
    • 84875261622 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase and metabolic control of immune responses
    • Munn DH, Mellor AL. Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol. 2013;34(3):137-143.
    • (2013) Trends Immunol , vol.34 , Issue.3 , pp. 137-143
    • Munn, D.H.1    Mellor, A.L.2


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