Signaling steps in the induction of genomic damage by insulin in colon and kidney cells

Free Radical Biology and Medicine

Volumn 68, Issue , 2014, Pages 247-257

  Othman, Eman Maher ^a,b   Hintzsche, Henning ^a   Stopper, Helga ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Minia University   (Egypt)

Author keywords

Diabetes; Free radicals; Genotoxicity; Insulin; Mitochondria; NADPH oxidase

Indexed keywords

DNA; INSULIN; INSULIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SOMATOMEDIN C RECEPTOR;

ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC PATIENT; DNA DAMAGE; ENZYME ACTIVATION; GENOTOXICITY; HUMAN; HUMAN CELL; HYPERINSULINEMIA; INTESTINE CELL; KIDNEY CELL; MITOCHONDRION; MOLECULAR MECHANICS; OXIDATIVE STRESS; PHOSPHORYLATION; PRIORITY JOURNAL; RISK FACTOR; SIGNAL TRANSDUCTION;

DIABETES; FREE RADICALS; GENOTOXICITY; INSULIN; MITOCHONDRIA; NADPH OXIDASE;

COLON; DIABETES MELLITUS; DNA DAMAGE; FREE RADICALS; GENE EXPRESSION REGULATION; HT29 CELLS; HUMANS; INSULIN; KIDNEY; NADPH OXIDASE; OXIDATIVE STRESS; PHOSPHORYLATION; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION;

EID: 84892662825     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.12.010     Document Type: Article

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