Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes

Cell

Volumn 172, Issue 3, 2018, Pages 549-563.e16

  Gee, Marvin H ^a   Han, Arnold ^a   Lofgren, Shane M ^a   Beausang, John F ^a   Mendoza, Juan L ^a   Birnbaum, Michael E ^a   Bethune, Michael T ^b   Fischer, Suzanne ^a   Yang, Xinbo ^a   Gomez Eerland, Raquel ^c   Bingham, David B ^a   Sibener, Leah V ^a   Fernandes, Ricardo A ^a   Velasco, Andrew ^a   Baltimore, David ^b   Schumacher, Ton N ^c   Khatri, Purvesh ^a   Quake, Stephen R ^a,d   Davis, Mark M ^a   Garcia, K Christopher ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b California Institute of Technology   (United States)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d CHAN ZUCKERBERG BIOHUB   (United States)

Author keywords

antigens; cancer; combinatorial biology; human leukocyte antigen; ligand identification; peptide library; peptides; single cell sequencing; T cell; T cell receptor

Indexed keywords

HLA ANTIGEN CLASS 1; PROTEOME; RNA; SPLICING FACTOR U2AF; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN; U2AF2 PROTEIN; UNCLASSIFIED DRUG; HLA A ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AGED; ALGORITHM; AMINO ACID SEQUENCE; ANTIGEN DETECTION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ANTIGENIC VARIATION; ARTICLE; BINDING AFFINITY; CELL STIMULATION; CELLULAR IMMUNITY; CLINICAL ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; EXOME; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MIDDLE AGED; MOLECULAR LIBRARY; PEPTIDE ANALYSIS; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS; SKW-3 CELL LINE; SURFACE PLASMON RESONANCE; TUMOR ASSOCIATED LEUKOCYTE; VALIDATION PROCESS; ADENOCARCINOMA; ANIMAL; CELL CULTURE; CHEMISTRY; COLORECTAL TUMOR; HEK293 CELL LINE; IMMUNOLOGY; PEPTIDE LIBRARY; SF9 CELL LINE; SPODOPTERA; TUMOR CELL LINE;

ADENOCARCINOMA; AGED; ANIMALS; ANTIGENS, NEOPLASM; CELL LINE, TUMOR; CELLS, CULTURED; COLORECTAL NEOPLASMS; HEK293 CELLS; HLA-A ANTIGENS; HUMANS; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; PEPTIDE LIBRARY; RECEPTORS, ANTIGEN, T-CELL; SF9 CELLS; SPODOPTERA;

EID: 85038814927     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.11.043     Document Type: Article

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