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Volumn 21, Issue 11, 2017, Pages 3317-3328

Hepatic Dysfunction Caused by Consumption of a High-Fat Diet

Author keywords

computational biology; high fat diet; insulin resistance; integrative modeling; obesity; omic data; systems biology

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; CYTOARCHITECTURE; DISEASE COURSE; EPIGENETICS; FAT INTAKE; GENE EXPRESSION; HEPATITIS; HIGH THROUGHPUT SCREENING; HISTOLOGY; IMAGE ANALYSIS; IMMUNOBLOTTING; INSULIN RESISTANCE; LIPID DIET; LIVER CELL; LIVER DYSFUNCTION; LIVER FUNCTION; LIVER TISSUE; MALE; METABOLIC SYNDROME X; METABOLISM; METABOLOMICS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEOMICS; RNA SEQUENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; LIVER; METABOLOME; PATHOLOGY; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; ULTRASTRUCTURE;

EID: 85037820239     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.11.059     Document Type: Article
Times cited : (62)

References (66)
  • 1
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • Anders, S., Huber, W., Differential expression analysis for sequence count data. Genome Biol., 11, 2010, R106.
    • (2010) Genome Biol. , vol.11 , pp. R106
    • Anders, S.1    Huber, W.2
  • 2
    • 84919690585 scopus 로고    scopus 로고
    • Cell-type-resolved quantitative proteomics of murine liver
    • Azimifar, S.B., Nagaraj, N., Cox, J., Mann, M., Cell-type-resolved quantitative proteomics of murine liver. Cell Metab. 20 (2014), 1076–1087.
    • (2014) Cell Metab. , vol.20 , pp. 1076-1087
    • Azimifar, S.B.1    Nagaraj, N.2    Cox, J.3    Mann, M.4
  • 4
    • 38649116056 scopus 로고    scopus 로고
    • Selective versus total insulin resistance: a pathogenic paradox
    • Brown, M.S., Goldstein, J.L., Selective versus total insulin resistance: a pathogenic paradox. Cell Metab. 7 (2008), 95–96.
    • (2008) Cell Metab. , vol.7 , pp. 95-96
    • Brown, M.S.1    Goldstein, J.L.2
  • 7
    • 2442710044 scopus 로고    scopus 로고
    • Genetic vulnerability to diet-induced obesity in the C57BL/6J mouse: physiological and molecular characteristics
    • Collins, S., Martin, T.L., Surwit, R.S., Robidoux, J., Genetic vulnerability to diet-induced obesity in the C57BL/6J mouse: physiological and molecular characteristics. Physiol. Behav. 81 (2004), 243–248.
    • (2004) Physiol. Behav. , vol.81 , pp. 243-248
    • Collins, S.1    Martin, T.L.2    Surwit, R.S.3    Robidoux, J.4
  • 10
    • 0021994683 scopus 로고
    • Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
    • DeFronzo, R.A., Gunnarsson, R., Björkman, O., Olsson, M., Wahren, J., Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J. Clin. Invest. 76 (1985), 149–155.
    • (1985) J. Clin. Invest. , vol.76 , pp. 149-155
    • DeFronzo, R.A.1    Gunnarsson, R.2    Björkman, O.3    Olsson, M.4    Wahren, J.5
  • 11
    • 78650315006 scopus 로고    scopus 로고
    • Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
    • Dunn, W.B., Broadhurst, D.I., Atherton, H.J., Goodacre, R., Griffin, J.L., Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem. Soc. Rev. 40 (2011), 387–426.
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 387-426
    • Dunn, W.B.1    Broadhurst, D.I.2    Atherton, H.J.3    Goodacre, R.4    Griffin, J.L.5
  • 13
    • 84871784819 scopus 로고    scopus 로고
    • Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis
    • Flegal, K.M., Kit, B.K., Orpana, H., Graubard, B.I., Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 309 (2013), 71–82.
    • (2013) JAMA , vol.309 , pp. 71-82
    • Flegal, K.M.1    Kit, B.K.2    Orpana, H.3    Graubard, B.I.4
  • 14
    • 21044445452 scopus 로고    scopus 로고
    • Apoptosis: a mechanism of acute and chronic liver injury
    • Guicciardi, M.E., Gores, G.J., Apoptosis: a mechanism of acute and chronic liver injury. Gut 54 (2005), 1024–1033.
    • (2005) Gut , vol.54 , pp. 1024-1033
    • Guicciardi, M.E.1    Gores, G.J.2
  • 15
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn, S.E., Hull, R.L., Utzschneider, K.M., Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444 (2006), 840–846.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 17
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: a brief overview
    • Kitano, H., Systems biology: a brief overview. Science 295 (2002), 1662–1664.
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 19
    • 79953177468 scopus 로고    scopus 로고
    • Aligning short sequencing reads with Bowtie
    • Unit 11.7
    • Langmead, B., Aligning short sequencing reads with Bowtie. Curr. Protoc. Bioinformatics, Chapter 11, 2010 Unit 11.7.
    • (2010) Curr. Protoc. Bioinformatics , vol.Chapter 11
    • Langmead, B.1
  • 20
    • 33846195875 scopus 로고    scopus 로고
    • Apoptosis in the pathophysiology of diabetes mellitus
    • Lee, S.C., Pervaiz, S., Apoptosis in the pathophysiology of diabetes mellitus. Int. J. Biochem. Cell Biol. 39 (2007), 497–504.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 497-504
    • Lee, S.C.1    Pervaiz, S.2
  • 22
    • 84924629414 scopus 로고    scopus 로고
    • Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
    • Love, M.I., Huber, W., Anders, S., Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol., 15, 2014, 550.
    • (2014) Genome Biol. , vol.15 , pp. 550
    • Love, M.I.1    Huber, W.2    Anders, S.3
  • 24
    • 54249156545 scopus 로고    scopus 로고
    • Metabolic syndrome: from epidemiology to systems biology
    • Lusis, A.J., Attie, A.D., Reue, K., Metabolic syndrome: from epidemiology to systems biology. Nat. Rev. Genet. 9 (2008), 819–830.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 819-830
    • Lusis, A.J.1    Attie, A.D.2    Reue, K.3
  • 25
    • 72849144434 scopus 로고    scopus 로고
    • Sequencing technologies – the next generation
    • Metzker, M.L., Sequencing technologies – the next generation. Nat. Rev. Genet. 11 (2010), 31–46.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 31-46
    • Metzker, M.L.1
  • 26
    • 0033636523 scopus 로고    scopus 로고
    • Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
    • Michael, M.D., Kulkarni, R.N., Postic, C., Previs, S.F., Shulman, G.I., Magnuson, M.A., Kahn, C.R., Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Mol. Cell 6 (2000), 87–97.
    • (2000) Mol. Cell , vol.6 , pp. 87-97
    • Michael, M.D.1    Kulkarni, R.N.2    Postic, C.3    Previs, S.F.4    Shulman, G.I.5    Magnuson, M.A.6    Kahn, C.R.7
  • 29
    • 80053921608 scopus 로고    scopus 로고
    • Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes
    • Oberbach, A., Blüher, M., Wirth, H., Till, H., Kovacs, P., Kullnick, Y., Schlichting, N., Tomm, J.M., Rolle-Kampczyk, U., Murugaiyan, J., et al. Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes. J. Proteome Res. 10 (2011), 4769–4788.
    • (2011) J. Proteome Res. , vol.10 , pp. 4769-4788
    • Oberbach, A.1    Blüher, M.2    Wirth, H.3    Till, H.4    Kovacs, P.5    Kullnick, Y.6    Schlichting, N.7    Tomm, J.M.8    Rolle-Kampczyk, U.9    Murugaiyan, J.10
  • 30
    • 84884403849 scopus 로고    scopus 로고
    • Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE)
    • Paull, E.O., Carlin, D.E., Niepel, M., Sorger, P.K., Haussler, D., Stuart, J.M., Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE). Bioinformatics 29 (2013), 2757–2764.
    • (2013) Bioinformatics , vol.29 , pp. 2757-2764
    • Paull, E.O.1    Carlin, D.E.2    Niepel, M.3    Sorger, P.K.4    Haussler, D.5    Stuart, J.M.6
  • 32
    • 0026520193 scopus 로고
    • Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
    • Pilkis, S.J., Granner, D.K., Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu. Rev. Physiol. 54 (1992), 885–909.
    • (1992) Annu. Rev. Physiol. , vol.54 , pp. 885-909
    • Pilkis, S.J.1    Granner, D.K.2
  • 34
    • 20144381544 scopus 로고    scopus 로고
    • Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death
    • Pyo, J.O., Jang, M.H., Kwon, Y.K., Lee, H.J., Jun, J.I., Woo, H.N., Cho, D.H., Choi, B., Lee, H., Kim, J.H., et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J. Biol. Chem. 280 (2005), 20722–20729.
    • (2005) J. Biol. Chem. , vol.280 , pp. 20722-20729
    • Pyo, J.O.1    Jang, M.H.2    Kwon, Y.K.3    Lee, H.J.4    Jun, J.I.5    Woo, H.N.6    Cho, D.H.7    Choi, B.8    Lee, H.9    Kim, J.H.10
  • 35
    • 84996538540 scopus 로고    scopus 로고
    • Antifibrotics in chronic liver disease: tractable targets and translational challenges
    • Ramachandran, P., Henderson, N.C., Antifibrotics in chronic liver disease: tractable targets and translational challenges. Lancet Gastroenterol. Hepatol. 1 (2016), 328–340.
    • (2016) Lancet Gastroenterol. Hepatol. , vol.1 , pp. 328-340
    • Ramachandran, P.1    Henderson, N.C.2
  • 37
    • 54949127160 scopus 로고    scopus 로고
    • iRefIndex: a consolidated protein interaction database with provenance
    • Razick, S., Magklaras, G., Donaldson, I.M., iRefIndex: a consolidated protein interaction database with provenance. BMC Bioinformatics, 9, 2008, 405.
    • (2008) BMC Bioinformatics , vol.9 , pp. 405
    • Razick, S.1    Magklaras, G.2    Donaldson, I.M.3
  • 38
    • 57349101675 scopus 로고    scopus 로고
    • A stress signaling pathway in adipose tissue regulates hepatic insulin resistance
    • Sabio, G., Das, M., Mora, A., Zhang, Z., Jun, J.Y., Ko, H.J., Barrett, T., Kim, J.K., Davis, R.J., A stress signaling pathway in adipose tissue regulates hepatic insulin resistance. Science 322 (2008), 1539–1543.
    • (2008) Science , vol.322 , pp. 1539-1543
    • Sabio, G.1    Das, M.2    Mora, A.3    Zhang, Z.4    Jun, J.Y.5    Ko, H.J.6    Barrett, T.7    Kim, J.K.8    Davis, R.J.9
  • 40
    • 70449119226 scopus 로고    scopus 로고
    • Diabetes and apoptosis: liver
    • Schattenberg, J.M., Schuchmann, M., Diabetes and apoptosis: liver. Apoptosis 14 (2009), 1459–1471.
    • (2009) Apoptosis , vol.14 , pp. 1459-1471
    • Schattenberg, J.M.1    Schuchmann, M.2
  • 41
    • 0036200587 scopus 로고    scopus 로고
    • Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression
    • Schrem, H., Klempnauer, J., Borlak, J., Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression. Pharmacol. Rev. 54 (2002), 129–158.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 129-158
    • Schrem, H.1    Klempnauer, J.2    Borlak, J.3
  • 42
    • 2642549921 scopus 로고    scopus 로고
    • Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation
    • Schrem, H., Klempnauer, J., Borlak, J., Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation. Pharmacol. Rev. 56 (2004), 291–330.
    • (2004) Pharmacol. Rev. , vol.56 , pp. 291-330
    • Schrem, H.1    Klempnauer, J.2    Borlak, J.3
  • 45
    • 0033636780 scopus 로고    scopus 로고
    • Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
    • Shimomura, I., Matsuda, M., Hammer, R.E., Bashmakov, Y., Brown, M.S., Goldstein, J.L., Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol. Cell 6 (2000), 77–86.
    • (2000) Mol. Cell , vol.6 , pp. 77-86
    • Shimomura, I.1    Matsuda, M.2    Hammer, R.E.3    Bashmakov, Y.4    Brown, M.S.5    Goldstein, J.L.6
  • 47
    • 84929148324 scopus 로고    scopus 로고
    • Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo
    • Titchenell, P.M., Chu, Q., Monks, B.R., Birnbaum, M.J., Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo. Nat. Commun., 6, 2015, 7078.
    • (2015) Nat. Commun. , vol.6 , pp. 7078
    • Titchenell, P.M.1    Chu, Q.2    Monks, B.R.3    Birnbaum, M.J.4
  • 49
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell, C., Pachter, L., Salzberg, S.L., TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25 (2009), 1105–1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 51
    • 84964720815 scopus 로고    scopus 로고
    • Network-based interpretation of diverse high-throughput datasets through the Omics Integrator software package
    • Tuncbag, N., Gosline, S.J., Kedaigle, A., Soltis, A.R., Gitter, A., Fraenkel, E., Network-based interpretation of diverse high-throughput datasets through the Omics Integrator software package. PLoS Comput. Biol., 12, 2016, e1004879.
    • (2016) PLoS Comput. Biol. , vol.12 , pp. e1004879
    • Tuncbag, N.1    Gosline, S.J.2    Kedaigle, A.3    Soltis, A.R.4    Gitter, A.5    Fraenkel, E.6
  • 53
    • 84877626901 scopus 로고    scopus 로고
    • Revisiting the mechanisms of metformin action in the liver
    • Viollet, B., Foretz, M., Revisiting the mechanisms of metformin action in the liver. Ann. Endocrinol. (Paris) 74 (2013), 123–129.
    • (2013) Ann. Endocrinol. (Paris) , vol.74 , pp. 123-129
    • Viollet, B.1    Foretz, M.2
  • 55
    • 84891789980 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatic apoptosis
    • Wang, K., Molecular mechanisms of hepatic apoptosis. Cell Death Dis., 5, 2014, e996.
    • (2014) Cell Death Dis. , vol.5 , pp. e996
    • Wang, K.1
  • 57
    • 84864464496 scopus 로고    scopus 로고
    • The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models
    • Wang, Z., Shah, O.J., Hunter, T., The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models. PLoS ONE, 7, 2012, e36961.
    • (2012) PLoS ONE , vol.7 , pp. e36961
    • Wang, Z.1    Shah, O.J.2    Hunter, T.3
  • 59
    • 84924891345 scopus 로고    scopus 로고
    • Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance
    • Williams, A.S., Kang, L., Zheng, J., Grueter, C., Bracy, D.P., James, F.D., Pozzi, A., Wasserman, D.H., Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance. J. Biol. Chem. 290 (2015), 6546–6557.
    • (2015) J. Biol. Chem. , vol.290 , pp. 6546-6557
    • Williams, A.S.1    Kang, L.2    Zheng, J.3    Grueter, C.4    Bracy, D.P.5    James, F.D.6    Pozzi, A.7    Wasserman, D.H.8
  • 60
    • 0029960055 scopus 로고    scopus 로고
    • TRANSFAC: a database on transcription factors and their DNA binding sites
    • Wingender, E., Dietze, P., Karas, H., Knüppel, R., TRANSFAC: a database on transcription factors and their DNA binding sites. Nucleic Acids Res. 24 (1996), 238–241.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 238-241
    • Wingender, E.1    Dietze, P.2    Karas, H.3    Knüppel, R.4
  • 63
    • 77954197778 scopus 로고    scopus 로고
    • Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model
    • Yizhak, K., Benyamini, T., Liebermeister, W., Ruppin, E., Shlomi, T., Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model. Bioinformatics 26 (2010), i255–i260.
    • (2010) Bioinformatics , vol.26 , pp. i255-i260
    • Yizhak, K.1    Benyamini, T.2    Liebermeister, W.3    Ruppin, E.4    Shlomi, T.5
  • 65
    • 84938086595 scopus 로고    scopus 로고
    • Nutritional systems biology of type 2 diabetes
    • Zhao, Y., Barrere-Cain, R.E., Yang, X., Nutritional systems biology of type 2 diabetes. Genes Nutr., 10, 2015, 481.
    • (2015) Genes Nutr. , vol.10 , pp. 481
    • Zhao, Y.1    Barrere-Cain, R.E.2    Yang, X.3


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