Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance

Journal of Biological Chemistry

Volumn 290, Issue 10, 2015, Pages 6546-6557

  Williams, Ashley S ^a   Kang, Li ^a   Zheng, Jenny ^a   Grueter, Carrie ^b   Bracy, Deanna P ^a   James, Freyja D ^a   Pozzi, Ambra ^a,b,c   Wasserman, David H ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c Division of Nephrology Department of Medicine Vanderbilt University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; FATTY ACIDS; GLUCOSE; INSULIN; METABOLISM; NUTRITION; PHYSIOLOGY;

GLUCOSE METABOLISM; GLUCOSE PRODUCTION; HEPATIC INSULIN RESISTANCE; HEPATIC STEATOSIS; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN SIGNALING; LIPID ACCUMULATIONS;

MAMMALS;

ALPHA1 INTEGRIN; COLLAGEN; FATTY ACID; GLUCOSE; INSULIN; VERY LATE ACTIVATION ANTIGEN 1; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET THERAPY; DISEASE SEVERITY; FATTY ACID METABOLISM; FATTY LIVER; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPID STORAGE; LIVER CELL; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; WILD TYPE; ANIMAL; BIOSYNTHESIS; GENETICS; HUMAN; KNOCKOUT MOUSE; LIVER; METABOLISM; PATHOLOGY;

MUS;

ANIMALS; DIET, HIGH-FAT; FATTY LIVER; GLUCOSE; HEPATOCYTES; HUMANS; INSULIN; INSULIN RESISTANCE; INTEGRIN ALPHA1; LIVER; MICE; MICE, KNOCKOUT; TRIGLYCERIDES;

EID: 84924891345     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.615716     Document Type: Article

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