High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization

Immunity

Volumn 47, Issue 6, 2017, Pages 1037-1050.e6

  Alcántara Hernández, Marcela ^a   Leylek, Rebecca ^a   Wagar, Lisa E ^a   Engleman, Edgar G ^a   Keler, Tibor ^b   Marinkovich, M Peter ^a,c   Davis, Mark M ^a   Nolan, Garry P ^a   Idoyaga, Juliana ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Celldex Therapeutics Inc   (United Kingdom)

^c VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

antibody targeting; Axl+ dendritic cells; C type lectins; CyTOF; dendritic cells; human; interindividual variation; plasmacytoid dendritic cells; subsets; tissue specialization

Indexed keywords

MONOCLONAL ANTIBODY; AXL RECEPTOR TYROSINE KINASE; BIOLOGICAL MARKER; CANCER VACCINE; DIFFERENTIATION ANTIGEN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; SIRPA PROTEIN, HUMAN;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BLOOD; CELL HETEROGENEITY; CELL SUBPOPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOID TISSUE; MOUSE; NONHUMAN; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; SPLEEN; TISSUE SPECIFICITY; TONSIL; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL VARIATION; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; CYTOLOGY; CYTOPHOTOMETRY; DEFICIENCY; GENE EXPRESSION; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; IMMUNOTHERAPY; LYMPH NODE; METABOLISM; MOLECULARLY TARGETED THERAPY; NEOPLASM; PALATINE TONSIL; PATHOLOGY; PROCEDURES;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; BIOLOGICAL VARIATION, INDIVIDUAL; BIOMARKERS; CANCER VACCINES; CYTOPHOTOMETRY; DENDRITIC CELLS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOPHENOTYPING; IMMUNOTHERAPY; LYMPH NODES; MICE; MICE, INBRED C57BL; MOLECULAR TARGETED THERAPY; NEOPLASMS; ORGAN SPECIFICITY; PALATINE TONSIL; PHENOTYPE; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, IMMUNOLOGIC; SKIN; SPLEEN;

EID: 85037058841     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.11.001     Document Type: Article

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