A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells

Journal of Cell Communication and Signaling

Volumn 12, Issue 1, 2018, Pages 157-170

  Kaur, Sukhbir ^a   Elkahloun, Abdel G ^b   Singh, Satya P ^c   Arakelyan, Anush ^d   Roberts, David D ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Angiogenesis; CD47; Endothelial mesenchymal transition; Extracellular vesicles; Tumor microenvironment; Tumor necrosis factor

Indexed keywords

ANTIBODY; B6H12 ANTIBODY; CD47 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; MESSENGER RNA; PROTEIN TYROSINE PHOSPHATASE SHP 2; THROMBOSPONDIN 1; TRANSCRIPTION FACTOR ZEB1; TUMOR NECROSIS FACTOR; TYROSINE; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ARTICLE; BREAST CARCINOMA; CANCER STEM CELL; CELL COMMUNICATION; CELL TRANSFORMATION; CELL TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIAL MESENCHYMAL TRANSITION; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; EXOSOME; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; HUVEC CELL LINE; IMMUNOMODULATION; LYMPHANGIOGENESIS; MCF-7 CELL LINE; MDA-MB-231 CELL LINE; METASTATIC BREAST CANCER; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN EXPRESSION LEVEL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STROMA; T-47D CELL LINE; THP-1 CELL LINE; TRANSCRIPTION REGULATION; TUMOR CELL; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR PROMOTION; UPREGULATION;

EID: 85035358923     PISSN: 18739601     EISSN: 1873961X     Source Type: Journal    
DOI: 10.1007/s12079-017-0428-0     Document Type: Article

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