TNFα induces inflammatory stress response in microvascular endothelial cells via Akt- and P38 MAP kinase-mediated thrombospondin-1 expression

Molecular and Cellular Biochemistry

Volumn 406, Issue 1-2, 2015, Pages 227-236

  Fairaq, Arwa ^a   Goc, Anna ^a   Artham, Sandeep ^a   Sabbineni, Harika ^a   Somanath, Payaningal R ^a,b  

^a UNIVERSITY OF GEORGIA   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Akt; Endothelium; Inflammation; P38 MAPK; TNF ; TSP 1

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; THROMBOSPONDIN 1; TUMOR NECROSIS FACTOR ALPHA; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR;

APOPTOSIS; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CAPILLARY PERMEABILITY; CELL PROLIFERATION; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME PHOSPHORYLATION; GENE; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN GENE; IN VITRO STUDY; INFLAMMATION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; ENDOTHELIUM CELL; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; MICROVASCULATURE; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PHYSIOLOGY; PROTEIN PROCESSING; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; VASCULAR ENDOTHELIUM;

APOPTOSIS; CAPILLARY PERMEABILITY; CELL PROLIFERATION; CELL SURVIVAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; HUMANS; MAP KINASE SIGNALING SYSTEM; MICROVESSELS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; STRESS, PHYSIOLOGICAL; THROMBOSPONDIN 1; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84945937477     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2440-0     Document Type: Article

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