Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy

Laboratory Investigation

Volumn 95, Issue 11, 2015, Pages 1291-1304

  Okumura, Naoki ^a,b   Minamiyama, Ryuki ^a   Ho, Leona T Y ^a   Kay, Eunduck P ^a   Kawasaki, Satoshi ^b   Tourtas, Theofilos ^c   Schlötzer Schrehardt, Ursula ^c   Kruse, Friedrich E ^c   Young, Robert D ^d   Quantock, Andrew J ^d   Kinoshita, Shigeru ^b   Koizumi, Noriko ^a  

^a DOSHISHA UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; COLLAGEN TYPE 1; FIBRONECTIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL1; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; ZEB1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CORNEA DYSTROPHY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIUM CELL; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FUCHS ENDOTHELIAL CORNEAL DYSTROPHY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; MOLECULAR PATHOLOGY; PERIODIC ACID SCHIFF STAIN; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; CONGENITAL CORNEA DYSTROPHY; GENETICS; METABOLISM; PHYSIOLOGY; TRANSFORMED CELL LINE;

CELL LINE, TRANSFORMED; EXTRACELLULAR MATRIX; FUCHS' ENDOTHELIAL DYSTROPHY; GENE KNOCKDOWN TECHNIQUES; HOMEODOMAIN PROTEINS; HUMANS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84945895032     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2015.111     Document Type: Article

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