Pre-clinical development of a humanized anti-CD47 antibody with anti-cancer therapeutic potential

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Liu, Jie ^a   Wang, Lijuan ^a   Zhao, Feifei ^a   Tseng, Serena ^a   Narayanan, Cyndhavi ^a   Shura, Lei ^a   Willingham, Stephen ^a   Howard, Maureen ^a   Prohaska, Susan ^a   Volkmer, Jens ^a   Chao, Mark ^a   Weissman, Irving L ^a   Majeti, Ravindra ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5F9; ANTINEOPLASTIC AGENT; HUMANIZED 5F9 G4; IMMUNOGLOBULIN G4; RITUXIMAB; UNCLASSIFIED DRUG; CD47 ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ANTIGEN BINDING; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER SURVIVAL; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG SAFETY; DRUG SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR MODEL; MOUSE; NONHODGKIN LYMPHOMA; NONHUMAN; PHAGOCYTOSIS; TOXICITY TESTING; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; FEMALE; HAPLORHINI; IMMUNOLOGY; LEUKEMIA, MYELOID, ACUTE; MACACA FASCICULARIS; PATHOLOGY; TUMOR CELL CULTURE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIBODY AFFINITY; ANTIGENS, CD47; ANTINEOPLASTIC AGENTS; FEMALE; HAPLORHINI; HUMANS; LEUKEMIA, MYELOID, ACUTE; MACACA FASCICULARIS; MICE; MICE, INBRED BALB C; PHAGOCYTOSIS; RITUXIMAB; TUMOR CELLS, CULTURED;

EID: 84946615733     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137345     Document Type: Article

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