VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation

FASEB Journal

Volumn 29, Issue 1, 2015, Pages 227-238

  Huang, Hua ^a   Langenkamp, Elise ^a   Georganaki, Maria ^a   Loskog, Angelica ^a   Fuchs, Peder Fredlund ^b   Dieterich, Lothar C ^a,c   Kreuger, Johan ^b   Dimberg, Anna ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c ETH ZURICH   (Switzerland)

Author keywords

Adhesion molecule; Leukocyte recruitment

Indexed keywords

B LYMPHOCYTE RECEPTOR; CXCL11 CHEMOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON REGULATORY FACTOR 1; MESSENGER RNA; STAT PROTEIN; SUNITINIB; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CD3+ T LYMPHOCYTE; CELL ADHESION; CONTROLLED STUDY; DERMAL MICROVASCULAR ENDOTHELIAL CELL; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; JURKAT CELL LINE; LEUKOCYTE; LEUKOCYTE ADHERENCE; LYMPHOCYTIC INFILTRATION; MALE; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR MICROENVIRONMENT; UPREGULATION; ANIMAL; C57BL MOUSE; ENDOTHELIUM CELL; EXPERIMENTAL MELANOMA; METABOLISM; MICROFLUIDIC ANALYSIS; PATHOLOGY; PHYSIOLOGY; TUMOR ASSOCIATED LEUKOCYTE; UMBILICAL VEIN ENDOTHELIAL CELL;

MUS;

ANIMALS; CELL ADHESION; CHEMOKINE CXCL10; CHEMOKINE CXCL11; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; JURKAT CELLS; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICROFLUIDIC ANALYTICAL TECHNIQUES; NF-KAPPA B; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR MICROENVIRONMENT; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84928705533     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-250985     Document Type: Article

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